Aliases for TFG Gene
External Ids for TFG Gene
Previous GeneCards Identifiers for TFG Gene
There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
GeneCards Summary for TFG Gene
TFG (TRK-Fused Gene) is a Protein Coding gene. Diseases associated with TFG include Hereditary Motor And Sensory Neuropathy, Okinawa Type and Spastic Paraplegia 57, Autosomal Recessive. Among its related pathways are Vesicle-mediated transport and Transport to the Golgi and subsequent modification. GO annotations related to this gene include identical protein binding and signal transducer activity.
UniProtKB/Swiss-Prot for TFG Gene
Plays a role in the normal dynamic function of the endoplasmic reticulum (ER) and its associated microtubules (PubMed:23479643, PubMed:27813252).