TFEB Gene
protein-coding GIFtS: 53
GCID: GC06M041651
|
|
transcription factor EB
| |
Aliases
for TFEB gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Transcription Factor EB1 2 | | BHLHE352 3 | | TCFEB1 2 5 | | ALPHATFEB2 | | BHLHe351 | | T-Cell Transcription Factor EB2 | | Class E Basic Helix-Loop-Helix Protein 352 3 | | |
Export aliases for TFEB gene to outside databasesPrevious GC identifers: GC06M041698 GC06M041759 GC06M041370 |
Summaries
for TFEB gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: TFEB_HUMAN, P19484Function: Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). EfficientDNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. Inassociation with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependentantibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes andbinds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading toactivate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizesthe gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signaltransduction processes required for normal vascularization of the placenta
Gene Wiki entry for TFEB
|
Genomic Views
for TFEB gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TFEB gene promoter:
USF1 C/EBPbeta Brachyury SREBP-1c FOXD1 SREBP-1b CREB SREBP-1a USF-1 deltaCREB
Other transcription factors
Search SABiosciences Chromatin IP Primers for TFEB
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TFEB |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p21TFEB Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06M041651: view genomic region
(about GC identifiers)
Start:
|
41,651,716 bp from pter |
End:
|
41,703,997 bp from pter |
Size:
|
52,282 bases |
Orientation:
|
minus strand |
|
Proteins
for TFEB gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TFEB_HUMAN, P19484 (See
protein sequence)Recommended Name: Transcription factor EB Size: 476 amino acids; 52865 Da
Subunit: Homodimer and heterodimer; with TFE3 or MITF
Subcellular location: Cytoplasm. Nucleus. Note=Mainly present in the cytoplasm. Under aberrant lysosomal storageconditions, it translocates from the cytoplasm to the nucleus
Sequence caution: Sequence=AAA36730.1; Type=Erroneous initiation; Sequence=CAE77681.1; Type=Erroneous initiation;
Secondary accessions: Q709B3 Q7Z6P9 Q9BRJ5 Q9UJD8Alternative splicing: 2 isoforms: P19484-1 P19484-2 Explore the universe of human proteins at neXtProt for TFEB: NX_P19484
Post-translational modifications:
Sumoylated; does not affect dimerization with MITF1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P19484
TFEB Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (5 alternative transcripts):
NP_001161299.2 NP_001258872.1 NP_001258873.1 NP_001258874.1 NP_009093.1
ENSEMBL proteins: ENSP00000383998 ENSP00000343948 ENSP00000230323 ENSP00000351742 ENSP00000362124 ENSP00000377824 ENSP00000410391 ENSP00000406491 ENSP00000400276 ENSP00000396168 ENSP00000393874 ENSP00000389468 ENSP00000415035 ENSP00000395208 ENSP00000415946 ENSP00000384203 ENSP00000412551
Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
TFEB for ontologies About GeneDecksing
TFEB Antibody Products:
Assay Products for TFEB: |
Protein
Domains /
Families
for TFEB gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TFEB for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P19484ProtoNet protein and cluster: P19484 1 Blocks protein family: IPB001092 Basic helix-loop-helix dimerization domain bHLH
UniProtKB/Swiss-Prot: TFEB_HUMAN, P19484Domain: The leucin zipper region is essential for homo- or heterodimerization and high-affinity DNA binding. DNAbinding is mediated by the basic regionSimilarity: Belongs to the MiT/TFE familySimilarity: Contains 1 bHLH (basic helix-loop-helix) domain |
Function
for TFEB gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: TFEB_HUMAN, P19484Function: Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). EfficientDNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. Inassociation with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependentantibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes andbinds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading toactivate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizesthe gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signaltransduction processes required for normal vascularization of the placenta Genatlas biochemistry entry for TFEB:transcription factor EB,highly recognizing the EB box sequences in the heavy chain immunoglobulin enhancer,murine Tcfebortholog
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TFEB (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TFEB (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TFEB (NM_007162) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TFEB | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TFEB |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TFEB |
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view): About this table
TFEB for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Tfebtm1Est for TFEB
8 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Tfeb):
TFEB for phenotypes About GeneDecksing
|
Pathways & Interactions
for TFEB gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Apoptosis and Autophagy | | | 2 | Translational Control | |
Pathway sources
See GeneCards unified pathways
Show all pathways
2 
Cell Signaling Technology (CST) Pathways for TFEB
TFEB for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TFEB
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/7 Interacting proteins for TFEB (P194843 ENSP000002303234) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 5/6 biological process terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0001892 | embryonic placenta development |
ISS | -- | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
NAS | 2115126 | | GO:0006959 | humoral immune response |
ISS | -- | | GO:0045893 | positive regulation of transcription, DNA-dependent |
-- | -- |
TFEB for ontologies About GeneDecksing
|
Drugs & Compounds
for TFEB gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TFEB for compounds About GeneDecksing
 Browse Tocris compounds for TFEB
1 Novoseek chemical compound relationship for TFEB gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| leucine |
54.8 |
5 |
7727380 (3), 15118077 (1), 1748288 (1) |
Search CenterWatch for drugs/clinical trials and news about TFEB
|
Transcripts
for TFEB gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TFEB gene (5 alternative transcripts): NM_001167827.2 NM_001271943.1 NM_001271944.1 NM_001271945.1 NM_007162.2 Unigene Cluster for TFEB: Transcription factor EB Hs.485360 [show with all ESTs]Unigene Representative Sequence: AK09506118 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000406563 ENST00000343317(uc021yzl.1) ENST00000230323(uc003oqs.1)
ENST00000358871(uc003oqr.1 uc003oqu.1) ENST00000373033(uc003oqt.1)
ENST00000394283(uc003oqv.1 uc010jxo.1 uc003oqx.1 uc003oqz.1)
ENST00000494822 ENST00000419396 ENST00000416140(uc003oqy.1) ENST00000419574(uc003oqw.1)
ENST00000424495 ENST00000445214(uc010jxp.1) ENST00000419788 ENST00000425401
ENST00000445700 ENST00000433032 ENST00000403298 ENST00000420312(uc010jxq.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TFEB (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TFEB (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): TFEB (NM_007162) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TFEB | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TFEB |
Additional cDNA sequence: AJ608786.1 AJ608787.1 AJ608788.1 AJ608789.1 AJ608790.1 AJ608791.2 AJ608793.1 AJ608794.1 AK095061.1 AK298390.1 AK310063.1 BC006225.2 BC032448.1 M33782.1 16 DOTS entries: DT.112337 DT.91856791 DT.86841555 DT.100778646 DT.40109916 DT.102830665 DT.100778644 DT.102830666 DT.102830661 DT.100000651 DT.121304195 DT.97845067 DT.100808882 DT.121304237 DT.121645419 DT.121645387 24/154 AceView cDNA sequences (see all 154): AJ608792 AI475796 BM504682 AW403857 BE264787 BQ049410 AA814469 AJ608789 R22427 BE253794 CR595362 AA235980 BX108797 BU540780 AJ608787 BF513669 CK822476 CR614783 BM714352 AJ608791 BQ932979 NM_007162 AW516948 AL134660
GeneLoc Exon Structure
|
Expression
for TFEB gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TFEB expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTTGAGGGGT
About this image
See TFEB Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TFEB
SOURCE GeneReport for Unigene cluster: Hs.485360
SABiosciences Custom PCR Arrays for TFEB
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TFEB
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TFEB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TFEB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TFEB | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TFEB |
Orthologs
for TFEB gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TFEB gene from 5/18 species (see all 18) About this table
ENSEMBL Gene Tree for TFEB (if available)
TreeFam Gene Tree for TFEB (if available) |
Paralogs
for TFEB gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TFEB gene
- MITF2 TFE32 TFEC2
4 SIMAP similar genes for TFEB using alignment to 13 protein entries: TFEB_HUMAN (see all proteins):AlphaTFEB TFEC TFE3 MITF
TFEB for paralogs About GeneDecksing
|
Genomic Variants
for TFEB gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TFEB (41651716 - 41703997 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for TFEB
3 CNVs: 69497 31286 3609 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TFEB |
|
Disorders
/ Diseases
for TFEB gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TFEB for disorders About GeneDecksing
OMIM gene information: 600744
OMIM disorders: --
11  diseases for TFEB: About MalaCardsalveolar soft part sarcoma pycnodysostosis microphthalmia angiomyolipoma
osteopetrosis renal cell carcinoma adhd renal carcinoma
carcinoma sarcoma leukemia
2 diseases from the University of Copenhagen DISEASES database for TFEB:Microphthalmia Renal cell carcinoma 6 Novoseek disease relationships for TFEB gene About this table
Export disorders for TFEB gene to outside databases
|
Publications
for TFEB gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TFEB gene, integrated from 9 sources (see all 50):
(articles sorted by number of sources associating them with TFEB) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A helix-loop-helix protein related to the immunoglobulin E box- binding proteins. (PubMed id 2115126)1, 2, 3, 9 Carr C.S. and Sharp P.A. (1990)
- A gene network regulating lysosomal biogenesis and function. (PubMed id 19556463)1, 2, 9 Sardiello M.... Ballabio A. (2009)
- Regulation of the MiTF/TFE bHLH-LZ transcription factors through restricted spatial expression and alternative splicing of functional domains. (PubMed id 15118077)1, 2, 9 Kuiper R.P....Geurts van Kessel A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
- Renal carcinomas with the t(6;11)(p21;q12): clinicopathologic features and demonstration of the specific alpha-TFEB gene fusion by immunohistochemistry, RT-PCR, and DNA PCR. (PubMed id 15644781)1, 9 Argani P....Ladanyi M. (2005)
- Upregulation of the transcription factor TFEB in t(6;11)(p21;q13)- positive renal cell carcinomas due to promoter substitution. (PubMed id 12837690)1, 9 Kuiper R.P....Geurts van Kessel A. (2003)
- TFEB has DNA-binding and oligomerization properties of a unique helix-loop-helix/leucine-zipper family. (PubMed id 1748288)2, 9 Fisher D.E.... Sharp P.A. (1991)
- Cloning of an Alpha-TFEB fusion in renal tumors harbo ring the t(6;11)(p21;q13) chromosome translocation. (PubMed id 12719541)1, 9 Davis I.J....Fisher D.E. (2003)
- TFE3, a transcription factor homologous to microphthalmia, is a potential transcriptional activator of tyrosinase and TyrpI genes. (PubMed id 10707962)1, 9 Verastegui C....Ballotti R. (2000)
|
External Searches for TFEB gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TFEB gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TFEB gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TFEB gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for TFEB gene:
Search GeneIP for patents involving TFEB
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TFEB gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for TFEB | | OriGene shRNA RFP for TFEB | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TFEB | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TFEB | | | OriGene Protein Over-expression Lysate for TFEB | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TFEB | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TFEB | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TFEB | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TFEB | | OriGene Custom Protein Services for TFEB | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TFEB | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TFEB | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TFEB | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TFEB | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TFEB | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TFEB |
| |
 |  |  |  | |
| | Antibodies & Assays for TFEB |
| | | | Search Tocris compounds for TFEB |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | TFEB Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TFEB |
|  |  |  | | | | ThermoFisher Antibodies for TFEB |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TFEB |
|
|
|
|
