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TFCP2L1 Gene

protein-coding   GIFtS: 51
GCID: GC02M121974

Transcription Factor CP2-Like 1

  Search for TFCP2L1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transcription Factor CP2-Like 11 2     CRTR-12 3
CRTR12 3 5     CP2-Related Transcriptional Repressor 12 3
LBP92 3 5     LBP-92
Transcription Factor LBP-92 3     Transcription Factor CP2-Like Protein 12

External Ids:    HGNC: 179251   Entrez Gene: 298422   Ensembl: ENSG000001151127   OMIM: 6097855   UniProtKB: Q9NZI63   

Export aliases for TFCP2L1 gene to outside databases

Previous GC identifers: GC02M122073 GC02M121694 GC02M114296


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TFCP2L1 Gene:
TFCP2L1 (transcription factor CP2-like 1) is a protein-coding gene. GO annotations related to this gene include transcription corepressor activity and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is UBP1.

UniProtKB/Swiss-Prot: TF2L1_HUMAN, Q9NZI6
Function: Transcriptional suppressor. May suppress UBP1-mediated transcriptional activation. Required for normal
duct development in the salivary gland and kidney (By similarity). Modulates the placental expression of CYP11A1




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TFCP2L1 gene promoter:
         c-Fos   E2F-1   E2F   AP-1   ATF-2   E2F-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTFCP2L1 promoter sequence
   Search Chromatin IP Primers for TFCP2L1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TFCP2L1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q14   Ensembl cytogenetic band:  2q14.2   HGNC cytogenetic band: 2q14

TFCP2L1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TFCP2L1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M121974:  view genomic region     (about GC identifiers)

Start:
121,974,163 bp from pter      End:
122,042,783 bp from pter
Size:
68,621 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TF2L1_HUMAN, Q9NZI6 (See protein sequence)
Recommended Name: Transcription factor CP2-like protein 1  
Size: 479 amino acids; 54627 Da
Secondary accessions: Q4ZG43

Explore the universe of human proteins at neXtProt for TFCP2L1: NX_Q9NZI6

Explore proteomics data for TFCP2L1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TFCP2L1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055368.1  
    ENSEMBL proteins: 
     ENSP00000263707  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR007604 CP2
     IPR013761 SAM/pointed

    Graphical View of Domain Structure for InterPro Entry Q9NZI6

    ProtoNet protein and cluster: Q9NZI6

    UniProtKB/Swiss-Prot: TF2L1_HUMAN, Q9NZI6
    Similarity: Belongs to the grh/CP2 family. CP2 subfamily


    Find genes that share domains with TFCP2L1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TF2L1_HUMAN, Q9NZI6
    Function: Transcriptional suppressor. May suppress UBP1-mediated transcriptional activation. Required for normal
    duct development in the salivary gland and kidney (By similarity). Modulates the placental expression of CYP11A1

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity TAS10644752
    GO:0003714transcription corepressor activity TAS10644752
    GO:0005515protein binding ----
         
    Find genes that share ontologies with TFCP2L1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TFCP2L1:
     Synthetic lethal with Ras 

         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Tfcp2l1):
     digestive/alimentary  endocrine/exocrine gland  growth/size/body  homeostasis/metabolism  mortality/aging 
     renal/urinary system 

    Find genes that share phenotypes with TFCP2L1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Tfcp2l1tm1.1Sjt for TFCP2L1

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TFCP2L1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TFCP2L1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TFCP2L1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TFCP2L1

    Transcription Factor Targeting: 
    Targeting motifs: HOMER Transcription Factor Regulatory Elements motif viewer 
                                          Consensus sequence:  NAAACCGGTTCAAACCGGTT 

    miRNA
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    miRTarBase miRNAs that target TFCP2L1:
    hsa-mir-215-5p (MIRT024786), hsa-mir-192-5p (MIRT026438)

    Block miRNA regulation of human, mouse, rat TFCP2L1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TFCP2L1 (see all 81):
    hsa-miR-642a hsa-miR-3194-5p hsa-miR-15a hsa-miR-519a hsa-miR-3916 hsa-miR-10b* hsa-miR-890 hsa-miR-510
    SwitchGear 3'UTR luciferase reporter plasmidTFCP2L1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TFCP2L1
    Predesigned siRNA for gene silencing in human, mouse, rat TFCP2L1

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector: TFCP2L1 (NM_014553)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TFCP2L1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TFCP2L1

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TFCP2L1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TF2L1_HUMAN, Q9NZI6: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    mitochondrion4
    cytoskeleton3
    cytosol1
    extracellular1
    lysosome1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005730nucleolus ----
    GO:0005737cytoplasm IEA--
    GO:0005739mitochondrion ----
    GO:0016020membrane IEA--

    Find genes that share ontologies with TFCP2L1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Array including TFCP2L1: 
              Embryonic Stem Cells in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for TFCP2L1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for TFCP2L1 (Q9NZI63 ENSP000002637074) via UniProtKB, MINT, STRING, and/or I2D (see all 89)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000206454Q018603I2D: score=1 
    ENSG00000229094Q018603I2D: score=1 
    ENSG00000230336Q018603I2D: score=1 
    ENSG00000233911Q018603I2D: score=1 
    ENSG00000235068Q018603I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0000902cell morphogenesis IEA--
    GO:0002070epithelial cell maturation IEA--
    GO:0006351transcription, DNA-templated IEA--
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS10644752

    Find genes that share ontologies with TFCP2L1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TFCP2L1 (TF2L1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TFCP2L1 gene: 
    NM_014553.2  

    Unigene Cluster for TFCP2L1:

    Transcription factor CP2-like 1
    Hs.156471  [show with all ESTs]
    Unigene Representative Sequence: NM_014553
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263707(uc010flq.3 uc002tmx.3 uc010flr.3) ENST00000464621

    miRNA
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    Block miRNA regulation of human, mouse, rat TFCP2L1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TFCP2L1 (see all 81):
    hsa-miR-642a hsa-miR-3194-5p hsa-miR-15a hsa-miR-519a hsa-miR-3916 hsa-miR-10b* hsa-miR-890 hsa-miR-510
    SwitchGear 3'UTR luciferase reporter plasmidTFCP2L1 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TFCP2L1
    Predesigned siRNA for gene silencing in human, mouse, rat TFCP2L1
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    OriGene clones in human, mouse for TFCP2L1 (see all 5)
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TFCP2L1 (NM_014553)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TFCP2L1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TFCP2L1
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TFCP2L1
      QuantiTect SYBR Green Assays in human, mouse, rat TFCP2L1
      QuantiFast Probe-based Assays in human, mouse, rat TFCP2L1

    Additional mRNA sequence: 

    AF198488.1 AK311692.1 AL137740.1 BC020554.1 BC064698.1 

    5 DOTS entries:

    DT.91862522  DT.422508  DT.120955316  DT.95145561  DT.75103289 

    Selected AceView cDNA sequences (see all 114):

    AI075110 AW772315 BC020554 BE328851 BE674454 AA677440 CK429551 AA865554 
    AI189643 BQ012939 CA944724 AI151375 AW271767 AI973244 AI241361 AW169738 
    BE138747 AI245431 CB242367 BU753934 AI985135 BE327117 BQ045123 AI453406 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TFCP2L1    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c ^ 15 ^ 16 ^ 17a · 17b · 17c
    SP1:              -     -                                                           -                                             
    SP2:                                                                                                                              
    SP3:                                                                                                  -                           
    SP4:                                                                                                                              


    ECgene alternative splicing isoforms for TFCP2L1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TFCP2L1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTTTGTACC
    TFCP2L1 Expression
    About this image


    TFCP2L1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 4 entries
             Inner Cell Mass Cells Inner Cell Mass
             B6 mouse embryonic stem cells
     
     Kidney (Urinary System)    fully expand to see all 3 entries
             Ureteric Bud Cells Ureteric Bud
             Ureteric Bud
     
     Gonad
             Primordial Germ Cells Allantois
     
     Placenta (Extraembryonic Tissues)
             Primordial Germ Cells Allantois
     
     Colon (Gastrointestinal Tract)
    TFCP2L1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TFCP2L1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.156471

    UniProtKB/Swiss-Prot: TF2L1_HUMAN, Q9NZI6
    Tissue specificity: Highly expressed in placental JEG-3 cells and very low levels of expression in
    non-steroidogenic cells. No expression was seen in adrenal NCI-H295A cells or in adrenal tissue

        Pathway & Disease-focused RT2 Profiler PCR Array including TFCP2L1: 
              Embryonic Stem Cells in human mouse rat

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    QuantiFast Probe-based Assays in human, mouse, rat TFCP2L1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TFCP2L1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TFCP2L1 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tfcp2l11 , 5 transcription factor CP2-like 11, 5 88.45(n)1
    93.53(a)1
      1 (52.14 cM)5
    818791  NM_023755.21  NP_076244.21 
     1186279455 
    chicken
    (Gallus gallus)
    Aves TFCP2L11 transcription factor CP2-like 1 79.23(n)
    89.05(a)
      424238  XM_004942906.1  XP_004942963.1 
    lizard
    (Anolis carolinensis)
    Reptilia TFCP2L16
    transcription factor CP2-like 1
    90(a)
    1 ↔ 1
    1(84261008-84305089)
    African clawed frog
    (Xenopus laevis)
    Amphibia lbp-9-prov2 LBP protein; likely ortholog of mouse CRTR-1 78.5(n)    BC044100.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tfcp2l16
    transcription factor CP2-like 1
    67(a)
    1 ↔ 1
    9(39345228-39364059) ENSDARG00000029497


    ENSEMBL Gene Tree for TFCP2L1 (if available)
    TreeFam Gene Tree for TFCP2L1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TFCP2L1 gene
    UBP12  GRHL32  GRHL12  TFCP22  GRHL22  
    3 SIMAP similar genes for TFCP2L1 using alignment to 1 protein entry:     TF2L1_HUMAN:
    DKFZp564C0164    TFCP2    UBP1

    Find genes that share paralogs with TFCP2L1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TFCP2L1 (see all 1566)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1914697211,2
    --121973892(+) TAGGAG/TAATCA 1 -- int10--------
    rs1112567541,2
    C--121974033(+) CAACAA/C/GTGTGA 1 -- int13CSA WA EA 240
    rs1828205881,2
    --121974082(+) GAAGAC/TGGTAA 1 -- int10--------
    rs1164409461,2
    C,F--121974372(+) CCCCGA/GCAGAT 1 -- ut311Minor allele frequency- G:0.03WA 118
    rs1861602241,2
    --121974398(+) AGAAAA/GGAGTC 1 -- ut310--------
    rs1906880541,2
    C--121974629(+) CCAGCA/GCTGTG 1 -- ut310--------
    rs1841786231,2
    --121974671(+) ATGAGA/GTCTGC 1 -- ut310--------
    rs43359501,2
    F,H--121974699(+) GACACC/TAGGAA 1 -- ut314Minor allele frequency- T:0.00NS EA 418
    rs745067741,2
    C,F--121974718(+) TGGCTC/TGGGCC 1 -- ut312Minor allele frequency- T:0.09CSA WA 120
    rs779378361,2
    C--121974747(+) CTGGCC/TCCCAT 1 -- ut312Minor allele frequency- T:0.09CSA WA 120

    HapMap Linkage Disequilibrium report for TFCP2L1 (121974163 - 122042783 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for TFCP2L1:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2658840CNV Deletion23128226
    nsv874974CNV Loss21882294
    nsv874975CNV Loss21882294
    nsv525727CNV Gain19592680

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609785    OMIM disorders: --


    Find genes that share disorders with TFCP2L1           About GenesLikeMe


    Export disorders for TFCP2L1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TFCP2L1 gene, integrated from 10 sources (see all 15):
    (articles sorted by number of sources associating them with TFCP2L1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc. (PubMed id 10644752)1, 2, 3, 9 Huang N. and Miller W.L. (J. Biol. Chem. 2000)
    2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. CRTR-1, a developmentally regulated transcriptional repressor related to the CP2 family of transcription factors. (PubMed id 11073954)1, 3 Rodda S....Rathjen P. (J. Biol. Chem. 2001)
    5. LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells. (PubMed id 15471945)1, 9 Huang N. and Miller W.L. (Mol. Endocrinol. 2005)
    6. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    7. Identification of a susceptibility locus in STAT4 for BehAset's disease in Han Chinese in a genome-wide association study. (PubMed id 23001997)1 Hou S....Yang P. (Arthritis Rheum. 2012)
    8. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)
    9. Modulation of CP2 family transcriptional activity by CRTR-1 and sumoylation. (PubMed id 20661472)1 To S....Keough R.A. (PLoS ONE 2010)
    10. Complementary quantitative proteomics reveals that transcription factor AP-4 mediates E-box-dependent complex formation for transcriptional repression of HDM2. (PubMed id 19505873)1 Ku W.C....Chen Y.J. (amp 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 29842 HGNC: 17925 AceView: TFCP2L1 Ensembl:ENSG00000115112 euGenes: HUgn29842
    ECgene: TFCP2L1 H-InvDB: TFCP2L1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TFCP2L1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TFCP2L1 gene:
    Search GeneIP for patents involving TFCP2L1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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