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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TFCP2 Gene

protein-coding   GIFtS: 60
GCID: GC12M051488

Transcription Factor CP2

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transcription Factor CP21 2     LSF1D2
LSF2 3     TFCP2C2
SEF2 3     Alpha-Globin Transcription Factor CP22
SAA3 Enhancer Factor2 3     Transcription Factor LSF3
LBP1C2     

External Ids:    HGNC: 117481   Entrez Gene: 70242   Ensembl: ENSG000001354577   OMIM: 1898895   UniProtKB: Q128003   

Export aliases for TFCP2 gene to outside databases

Previous GC identifers: GC12M051655 GC12P051583 GC12M051205 GC12M049774 GC12M048519


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TFCP2 Gene:
This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the
alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional
switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product
interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the
pathogenesis of Alzheimer's disease. (provided by RefSeq, Mar 2010)

GeneCards Summary for TFCP2 Gene: 
TFCP2 (transcription factor CP2) is a protein-coding gene. Diseases associated with TFCP2 include alzheimer's disease, and neuroendocrine tumor, and among its related super-pathways are Dichloroethylene metabolism. GO annotations related to this gene include DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is UBP1.

UniProtKB/Swiss-Prot: TFCP2_HUMAN, Q12800
Function: Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1
promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1
(By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of
the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells.
Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter

Gene Wiki entry for TFCP2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_029419.12  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TFCP2 gene promoter:
         E2F-3a   CREB   E2F-1   E2F   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTFCP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for TFCP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TFCP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q13

TFCP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TFCP2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M051488:  view genomic region     (about GC identifiers)

Start:
51,487,446 bp from pter      End:
51,566,926 bp from pter
Size:
79,481 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TFCP2_HUMAN, Q12800 (See protein sequence)
Recommended Name: Alpha-globin transcription factor CP2  
Size: 502 amino acids; 57256 Da
Subunit: Binds to DNA as a dimer, isoform 3 does not bind to DNA or affect the binding of isoform 1 to DNA.
Interacts with UBP1 and PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1 (By
similarity). Component of the SSP (stage selector protein) complex, which appears to be a heteromer of TFCP2 and
2 copies of NFE4
Subcellular location: Nucleus
Developmental stage: Expressed in fetal erythroid tissue
Miscellaneous: In PubMed:8114710 authors noted that a 10-fold molar excess of isoform 3 over isoform 1 inhibited
DNA-binding
Secondary accessions: A8K5E9 Q12801 Q9UD75 Q9UD77
Alternative splicing: 4 isoforms:  Q12800-1   Q12800-2   Q12800-3   Q12800-4   

Explore the universe of human proteins at neXtProt for TFCP2: NX_Q12800

Explore proteomics data for TFCP2 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q12800

  • TFCP2 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TFCP2 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001166923.1  NP_001166924.1  NP_005644.2  

    ENSEMBL proteins: 
     ENSP00000257915   ENSP00000449742   ENSP00000447991   ENSP00000449280   ENSP00000304411  

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    Cloud-Clone Corp. Proteins for TFCP2 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005634nucleus IEA--

    TFCP2 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR007604 CP2
     IPR013761 SAM/pointed

    Graphical View of Domain Structure for InterPro Entry Q12800

    ProtoNet protein and cluster: Q12800

    UniProtKB/Swiss-Prot: TFCP2_HUMAN, Q12800
    Similarity: Belongs to the grh/CP2 family. CP2 subfamily


    TFCP2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TFCP2_HUMAN, Q12800
    Function: Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1
    promoters. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1
    (By similarity). Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of
    the gamma-globin genes with enhancer elements contained in the locus control region in fetal erythroid cells.
    Interacts by binding to the stage selector element (SSE) in the proximal gamma-globin promoter

         Genatlas biochemistry entry for TFCP2:
    alpha-globin transcription factor,CP2,with homology to Drosophila transcription factor Elf-1/NTF-1,dimerizing with
    NFE2 to form the stage selector protein complex

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity TAS8157699
         
    TFCP2 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TFCP2:
     Decreased viability 

         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Tfcp2):
     normal 

    TFCP2 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tfcp2tm1Jmc for TFCP2

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TFCP2 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TFCP2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TFCP2 
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    SwitchGear 3'UTR luciferase reporter plasmidTFCP2 3' UTR sequence
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TFCP2 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Dichloroethylene metabolism
    Dichloroethylene metabolism1.00
    2Signaling events mediated by HDAC Class I
    Signaling events mediated by HDAC Class I

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for TFCP2
        Dichloroethylene metabolism


    1 GeneGo (Thomson Reuters) Pathway for TFCP2
        Dichloroethylene metabolism

    1 BioSystems Pathway for TFCP2
        Signaling events mediated by HDAC Class I



    TFCP2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TFCP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/50 Interacting proteins for TFCP2 (Q128002, 3 ENSP000002579154) via UniProtKB, MINT, STRING, and/or I2D (see all 50)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CASP8Q147902, 3, ENSP000003512734MINT-64085 I2D: score=5 STRING: ENSP00000351273
    COILP384322, 3, ENSP000002403164MINT-2863537 I2D: score=3 STRING: ENSP00000240316
    CALM1P621583I2D: score=1 
    CALM2P621583I2D: score=1 
    CALM3P621583I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS8157699

    TFCP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TFCP2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TFCP2

    1 Novoseek inferred chemical compound relationship for TFCP2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glycogen 16.6 2 16705182 (1), 16645641 (1)

    Search CenterWatch for drugs/clinical trials and news about TFCP2

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TFCP2 gene (3 alternative transcripts): 
    NM_001173452.1  NM_001173453.1  NM_005653.4  

    Unigene Cluster for TFCP2:

    Transcription factor CP2
    Hs.48849  [show with all ESTs]
    Unigene Representative Sequence: NM_005653
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000257915(uc009zly.1) ENST00000549867 ENST00000546822 ENST00000548115
    ENST00000548108 ENST00000307660(uc001rxw.3 uc001rxv.2 uc009zlx.2)

    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

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    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate TFCP2 (see all 15):
    hsa-miR-3163 hsa-miR-320a hsa-miR-136 hsa-miR-323b-3p hsa-miR-499-3p hsa-miR-320d hsa-miR-105 hsa-miR-320b
    SwitchGear 3'UTR luciferase reporter plasmidTFCP2 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK291264.1 AK308087.1 BC003634.2 M84810.1 U03494.1 U03495.1 

    14 DOTS entries:

    DT.91646720  DT.453604  DT.100786025  DT.100786026  DT.95213710  DT.121125035  DT.95284597  DT.95284581 
    DT.95339757  DT.91802026  DT.92436044  DT.92436047  DT.95284580  DT.95284593 

    24/382 AceView cDNA sequences (see all 382):

    R20718 BM803795 CR602520 AA742185 BM670643 AL548190 BC003379 AW069846 
    CA439769 CR597407 CR599664 AU077315 CR607073 AV650596 AI017025 CB147881 
    CB129703 AA333877 BM831904 AW955757 BC008712 NM_020467 CA430247 AI142906 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for TFCP2 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b
    SP1:                          -                                                                           
    SP2:                          -                                                                           
    SP3:                                                                                                      
    SP4:                                                                                                      
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for TFCP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TFCP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTTATTCTG
    TFCP2 Expression
    About this image


    See TFCP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TFCP2

    SOURCE GeneReport for Unigene cluster: Hs.48849

    UniProtKB/Swiss-Prot: TFCP2_HUMAN, Q12800
    Tissue specificity: Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung
    (at protein level)

        SABiosciences Expression via Pathway-Focused PCR Array including TFCP2: 
              HIV Host Response in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TFCP2 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tfcp21 , 5 transcription factor CP21, 5 88.38(n)1
    96.61(a)1
      15 (56.33 cM)5
    214221  NM_033476.21  NP_258437.11 
     1005027965 
    chicken
    (Gallus gallus)
    Aves TFCP21 transcription factor CP2 79.66(n)
    95.35(a)
      378900  NM_204384.1  NP_989715.1 
    lizard
    (Anolis carolinensis)
    Reptilia TFCP26
    Uncharacterized protein
    95(a)
    1 ↔ 1
    2(67456290-67504887)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.48682 Xenopus laevis transcription factor LSF (lsf) mRNA, more 80.8(n)    AY323528.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc10e042 Transcribed sequence with strong similarity to protein more 80.78(n)    BM776108.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta gem1 gemini 52.18(n)
    45.43(a)
      36064  NM_136712.3  NP_610556.1 


    ENSEMBL Gene Tree for TFCP2 (if available)
    TreeFam Gene Tree for TFCP2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TFCP2 gene
    UBP12  GRHL32  GRHL12  GRHL22  TFCP2L12  
    3 SIMAP similar genes for TFCP2 using alignment to 3 protein entries:     TFCP2_HUMAN (see all proteins):
    DKFZp564C0164    TFCP2L1    UBP1

    TFCP2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1765 SNPs in TFCP2 are shown (see all 1765)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs114481531,2
    C--48522989(+) AATAA-/TTTTTT 3 -- int10--------
    rs74885831,2
    C--48524514(+) aaaaaA/Ttagcc 3 -- int10--------
    rs674883561,2
    C--48525528(+) AAAAA-/A/AA  
            
    GAATG
    3 -- int11NA 2
    rs113080411,2
    C--48537054(+) CTTTGT/-TTTTT 3 -- int1 trp31Minor allele frequency- -:0.50CSA 2
    rs352994761,2
    C--48538807(+) GTCTC-/AAAAAA 3 -- int10--------
    rs38399871,2
    C--48544807(-) TCCAA-/AGCATT 3 -- int11Minor allele frequency- A:0.00CSA 2
    rs2005307961,2
    C--48544809(-) TTTCCA/CAAGCA 3 -- int10--------
    rs340312151,2
    C--48547422(+) AGTGA-/TTTTTT 3 -- int10--------
    rs1125229841,2
    C--48555787(+) TGGGGA/-GAAAA 3 -- int11Minor allele frequency- -:0.00CSA 2
    rs50197651,2
    C,A,H--48555788(+) TGGGGA/GAAAAA 3 -- int1 trp34Minor allele frequency- G:0.00NA CSA 9

    HapMap Linkage Disequilibrium report for TFCP2 (51487446 - 51566926 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TFCP2:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv703CNV Insertion18451855
    esv34039CNV Loss18971310


    Human Gene Mutation Database (HGMD): TFCP2
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TFCP2
    DNA2.0 Custom Variant and Variant Library Synthesis for TFCP2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 189889    OMIM disorders: --

    6 diseases for TFCP2:    About MalaCards
    alzheimer's disease    neuroendocrine tumor    down syndrome    atherosclerosis
    cerebritis    hepatocellular carcinoma


    TFCP2 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    1 Novoseek inferred disease relationship for TFCP2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    alzheimers disease 32.5 2 16710089 (1), 15860461 (1)

    Genetic Association Database (GAD): TFCP2
    Human Genome Epidemiology (HuGE) Navigator: TFCP2 (7 documents)

    Export disorders for TFCP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TFCP2 gene, integrated from 9 sources (see all 73):
    (articles sorted by number of sources associating them with TFCP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the genomic structure, chromosomal location, promoter, and development expression of the alpha-globin transcription factor CP2. (PubMed id 8157699)1, 2, 3, 9 Swendeman S.L.... Sheffery M. (1994)
    2. Purification and characterization of the serum amyloid A3 enhancer factor. (PubMed id 10455131)1, 2, 9 Bing Z.... Liao W.S.-L. (1999)
    3. Molecular cloning of the alpha-globin transcription factor CP2. (PubMed id 1732747)1, 2, 9 Lim L.C.... Sheffery M. (1992)
    4. Association of polymorphism in the transcription factor LBP-1c/CP2/LSF gene with Alzheimer's disease and major depression. (PubMed id 16710089)1, 4, 9 Schahab S....Kolsch H. (2006)
    5. Induction of human fetal globin gene expression by a novel erythroid factor, NF-E4. (PubMed id 11003662)1, 2, 9 Zhou W....Jane S.M. (2000)
    6. One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs. (PubMed id 8035790)1, 2, 9 Shirra M.K.... Hansen U. (1994)
    7. Further evidence for LBP-1c/CP2/LSF association in Alzheimer's disease families. (PubMed id 16272261)1, 4, 9 Bertram L....Tanzi R.E. (2005)
    8. Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein. (PubMed id 7828600)1, 2, 9 Jane S.M.... Cunningham J.M. (1995)
    9. No replication of genetic association between candida te polymorphisms and Alzheimer's disease. (PubMed id 19889475)1, 4 Cousin E....Campion D. (2009)
    10. Cluster Analysis of Risk Factor Genetic Polymorphisms in Alzheimer's Disease. (PubMed id 18307033)1, 4 Randall C.N....Poduslo S.E. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7024 HGNC: 11748 AceView: TFCP2 Ensembl:ENSG00000135457 euGenes: HUgn7024
    ECgene: TFCP2 H-InvDB: TFCP2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TFCP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TFCP2 gene:
    Search GeneIP for patents involving TFCP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

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