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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TFCP2 Gene

protein-coding   GIFtS: 59
GCID: GC12M051488

transcription factor CP2

 Explore 13 diseases affiliated with
TFCP2 via our new
 Human Malady Compendium 
Biological research products
for TFCP2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Transcription Factor CP21 2     LBP-1C1
LSF1 2 3     LBP1C2
TFCP2C1 2     LSF1D2
SEF2 3     Alpha-Globin Transcription Factor CP22
SAA3 Enhancer Factor2 3     Transcription Factor LSF3
CP21     

External Ids:    HGNC: 117481   Entrez Gene: 70242   Ensembl: ENSG000001354577   OMIM: 1898895   UniProtKB: Q128003   

Export aliases for TFCP2 gene to outside databases

Previous GC identifers: GC12M051655 GC12P051583 GC12M051205 GC12M049774 GC12M048519


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TFCP2:
This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the
alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch
of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts
with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of
Alzheimer's disease. (provided by RefSeq, Mar 2010)

UniProtKB/Swiss-Prot: TFCP2_HUMAN, Q12800
Function: Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters.
Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity).
Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes
with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the
stage selector element (SSE) in the proximal gamma-globin promoter

Gene Wiki entry for TFCP2


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TFCP2 gene promoter:
         E2F-3a   CREB   E2F-1   E2F   deltaCREB   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTFCP2 promoter sequence
   Search SABiosciences Chromatin IP Primers for TFCP2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TFCP2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13   Ensembl cytogenetic band:  12q13.13   HGNC cytogenetic band: 12q13

TFCP2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TFCP2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M051488:  view genomic region     (about GC identifiers)

Start:
51,487,446 bp from pter      End:
51,566,926 bp from pter
Size:
79,481 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TFCP2_HUMAN, Q12800 (See protein sequence)
Recommended Name: Alpha-globin transcription factor CP2  
Size: 502 amino acids; 57256 Da
Subunit: Binds to DNA as a dimer, isoform 3 does not bind to DNA or affect the binding of isoform 1 to DNA. Interacts
with UBP1 and PIAS1, and is probably part of a complex containing TFCP2, UBP1 and PIAS1 (By similarity). Component of
the SSP (stage selector protein) complex, which appears to be a heteromer of TFCP2 and 2 copies of NFE4
Subcellular location: Nucleus
Developmental stage: Expressed in fetal erythroid tissue
Miscellaneous: In PubMed:8114710 authors noted that a 10-fold molar excess of isoform 3 over isoform 1 inhibited
DNA-binding
Secondary accessions: A8K5E9 Q12801 Q9UD75 Q9UD77
Alternative splicing: 4 isoforms:  Q12800-1   Q12800-2   Q12800-3   Q12800-4   

Explore the universe of human proteins at neXtProt for TFCP2: NX_Q12800

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q12800

  • TFCP2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (3 alternative transcripts): 
    NP_001166923.1  NP_001166924.1  NP_005644.2  

    ENSEMBL proteins: 
     ENSP00000257915   ENSP00000449742   ENSP00000447991   ENSP00000449280   ENSP00000304411  

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    Uscn Proteins for TFCP2

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005634nucleus IEA--


    TFCP2 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TFCP2 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR007604 CP2
     IPR013761 SAM/pointed

    Graphical View of Domain Structure for InterPro Entry Q12800

    ProtoNet protein and cluster: Q12800

    UniProtKB/Swiss-Prot: TFCP2_HUMAN, Q12800
    Similarity: Belongs to the grh/CP2 family. CP2 subfamily


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: TFCP2_HUMAN, Q12800
    Function: Binds a variety of cellular and viral promoters including fibrinogen, alpha-globin, SV40 and HIV-1 promoters.
    Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with UBP1 (By similarity).
    Functions as part of the SSP (stage selector protein) complex. Facilitates the interaction of the gamma-globin genes
    with enhancer elements contained in the locus control region in fetal erythroid cells. Interacts by binding to the
    stage selector element (SSE) in the proximal gamma-globin promoter

         Genatlas biochemistry entry for TFCP2:
    alpha-globin transcription factor,CP2,with homology to Drosophila transcription factor Elf-1/NTF-1,dimerizing with NFE2
    to form the stage selector protein complex

    10/342 SABiosciences Target genes for TFCP2 (see all 342):
    ACRBP ADH1A ADH1B ADPGK AKR7A2 ALDH16A1 AMDHD1 AMPD2 AMZ1 ANKRD31

    miRNA
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    hsa-miR-3163 hsa-miR-320a hsa-miR-136 hsa-miR-323b-3p hsa-miR-499-3p hsa-miR-320d hsa-miR-105 hsa-miR-320b
    SwitchGear 3'UTR luciferase reporter plasmidTFCP2 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity TAS8157699


    TFCP2 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for TFCP2:
     Decreased viability 

    Animal Models:
         Mouse knock-out Tfcp2tm1Jmc for TFCP2
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Tfcp2):
     normal 

    TFCP2 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Dichloroethylene metabolism
    Dichloroethylene metabolism1.00
    Dichloroethylene metabolism1.00
    2Signaling events mediated by HDAC Class I
    Signaling events mediated by HDAC Class I1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for TFCP2
        Dichloroethylene metabolism


    1 GeneGo (Thomson Reuters) Pathway for TFCP2
        Dichloroethylene metabolism

    1 BioSystems Pathway for TFCP2 
        Signaling events mediated by HDAC Class I



    TFCP2 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TFCP2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 16)

    5/49 Interacting proteins for TFCP2 (Q128002, 3 ENSP000002579154) via UniProtKB, MINT, STRING, and/or I2D (see all 49)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CASP8Q147902, 3, ENSP000003512734MINT-64085 I2D: score=5 STRING: ENSP00000351273
    COILP384322, 3, ENSP000002403164MINT-2863537 I2D: score=3 STRING: ENSP00000240316
    CALM1P621583I2D: score=1 
    CALM2P621583I2D: score=1 
    CALM3P621583I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS8157699


    TFCP2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    TFCP2 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TFCP2
    1 Novoseek chemical compound relationship for TFCP2 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    glycogen 16.6 2 16705182 (1), 16645641 (1)

    Search CenterWatch for drugs/clinical trials and news about TFCP2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TFCP2 gene (3 alternative transcripts): 
    NM_001173452.1  NM_001173453.1  NM_005653.4  

    Unigene Cluster for TFCP2:

    Transcription factor CP2
    Hs.48849  [show with all ESTs]
    Unigene Representative Sequence: NM_005653
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000257915(uc009zly.1) ENST00000549867 ENST00000546822 ENST00000548115
    ENST00000548108 ENST00000307660(uc001rxw.3 uc001rxv.2 uc009zlx.2)


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    hsa-miR-3163 hsa-miR-320a hsa-miR-136 hsa-miR-323b-3p hsa-miR-499-3p hsa-miR-320d hsa-miR-105 hsa-miR-320b
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    Additional cDNA sequence: 

    AK291264.1 AK308087.1 BC003634.2 M84810.1 U03494.1 U03495.1 

    14 DOTS entries:

    DT.91646720  DT.453604  DT.100786025  DT.100786026  DT.95213710  DT.121125035  DT.95284597  DT.95284581 
    DT.95339757  DT.91802026  DT.92436044  DT.92436047  DT.95284580  DT.95284593 

    24/382 AceView cDNA sequences (see all 382):

    AA488618 AK001839 BM982348 NM_020467 BI061015 CB129703 BG491644 BI089401 
    CB216415 BQ050904 BF772763 CR619854 AA742185 NM_005653 AU077315 AL548190 
    BG023887 AI017025 AI921453 CB160696 AI753013 BG678644 AI377053 CB147881 

    GeneLoc Exon Structure

    5/6 Alternative Splicing Database (ASD) splice patterns (SP) for TFCP2 (see all 6)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b
    SP1:                          -                                                                           
    SP2:                          -                                                                           
    SP3:                                                                                                      
    SP4:                                                                                                      
    SP5:                                                                                                      


    ECgene alternative splicing isoforms for TFCP2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TFCP2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTTATTCTG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See TFCP2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TFCP2

    SOURCE GeneReport for Unigene cluster: Hs.48849

    UniProtKB/Swiss-Prot: TFCP2_HUMAN, Q12800
    Tissue specificity: Ubiquitous. Expressed in brain, ovary, kidney, thymus, spleen, liver, adrenal, heart and lung (at
    protein level)

        SABiosciences Expression via Pathway-Focused PCR Array including TFCP2: 
              HIV Host Response in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TFCP2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TFCP2 gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves TFCP21 transcription factor CP2 79.66(n)
    95.35(a)
      378900  NM_204384.1  NP_989715.1 
    lizard
    (Anolis carolinensis)
    Reptilia TFCP26
    --
    92(a)
    1 ↔ 1
    2(67460039-67502718)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.48682 Xenopus laevis transcription factor LSF (lsf) mRNA, more 80.8(n)    AY323528.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufc10e042 Transcribed sequence with strong similarity to protein more 80.78(n)    BM776108.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta gem1 gemini 52.18(n)
    45.43(a)
      36064  NM_136712.3  NP_610556.1 


    ENSEMBL Gene Tree for TFCP2 (if available)
    TreeFam Gene Tree for TFCP2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TFCP2 gene
    UBP12  GRHL32  GRHL12  GRHL22  TFCP2L12  
    3 SIMAP similar genes for TFCP2 using alignment to 3 protein entries:     TFCP2_HUMAN (see all proteins):
    DKFZp564C0164    TFCP2L1    UBP1

    TFCP2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1430 NCBI SNPs in TFCP2 are shown (see all 1430    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs672029281,2
    C--48519486(+) ATATT-/TAAAAA 3 -- ds50010--------
    rs1996502811,2
    C--48519503(-) TTTTTC/TTTTTT 3 -- ds50010--------
    rs782645081,2
    C,F,--48519669(+) AGACAC/TCTGGT 3 -- ds50014Minor allele frequency- T:0.10WA CSA NA 242
    rs590577761,2
    C,--48519969(+) TTCTAG/AATAAA 3 -- ut311Minor allele frequency- A:0.50WA 2
    rs583093791,2
    C,F,--48520004(+) CCATGA/TTGTTA 3 -- ut314Minor allele frequency- T:0.11WA CSA NA 242
    rs733019421,2
    C,F,--48520520(+) AAGGAG/AGGCCA 3 -- ut312Minor allele frequency- A:0.50WA CSA 4
    rs748585421,2
    C,F,--48520632(+) GTCACT/CATAGC 3 -- ut311Minor allele frequency- C:0.03WA 118
    rs1117344131,2
    F--48521206(+) ATTCAC/TATCCC 3 -- ut312Minor allele frequency- T:0.50CSA 4
    rs1124227591,2
    C,--48521799(+) GAGCCG/AAGATC 3 -- int11Minor allele frequency- A:0.50WA 2
    rs783825301,2
    F,--48521892(+) AGGAAC/TAATCT 3 -- int11Minor allele frequency- T:0.04NA 120

    HapMap Linkage Disequilibrium report for TFCP2 (51487446 - 51566926 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for TFCP2
         1 CNV: 47982
    Human Gene Mutation Database (HGMD): TFCP2

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TFCP2 for disorders           About GeneDecksing

    OMIM gene information: 189889    OMIM disorders: --

    13 diseases for TFCP2:    About MalaCards
    alzheimer's disease    hearing loss    alzheimer disease familial    neuroendocrine tumor
    down syndrome    hepatocellular carcinoma    neurodegeneration    atherosclerosis
    ataxia    cerebritis    cholesterol    immunodeficiency
    carcinoma

    1 Novoseek disease relationship for TFCP2 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    alzheimers disease 32.5 2 16710089 (1), 15860461 (1)

    Genetic Association Database (GAD): TFCP2
    Human Genome Epidemiology (HuGE) Navigator: TFCP2 (7 documents)

    Export disorders for TFCP2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TFCP2 gene, integrated from 9 sources (see all 71):
    (articles sorted by number of sources associating them with TFCP2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of the genomic structure, chromosomal location, promoter, and development expression of the alpha-globin transcription factor CP2. (PubMed id 8157699)1, 2, 3, 9 Swendeman S.L.... Sheffery M. (1994)
    2. Purification and characterization of the serum amyloid A3 enhancer factor. (PubMed id 10455131)1, 2, 9 Bing Z.... Liao W.S.-L. (1999)
    3. Molecular cloning of the alpha-globin transcription factor CP2. (PubMed id 1732747)1, 2, 9 Lim L.C.... Sheffery M. (1992)
    4. Induction of human fetal globin gene expression by a novel erythroid factor, NF-E4. (PubMed id 11003662)1, 2, 9 Zhou W....Jane S.M. (2000)
    5. One exon of the human LSF gene includes conserved regions involved in novel DNA-binding and dimerization motifs. (PubMed id 8035790)1, 2, 9 Shirra M.K.... Hansen U. (1994)
    6. Hemoglobin switching in man and chicken is mediated by a heteromeric complex between the ubiquitous transcription factor CP2 and a developmentally specific protein. (PubMed id 7828600)1, 2, 9 Jane S.M.... Cunningham J.M. (1995)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Association of the 3' UTR transcription factor LBP-1c/CP2/LSF polymorphism with late-onset Alzheimer's disease. (PubMed id 12555245)1, 4 Luedecking-Zimmer E....Kamboh M.I. (2003)
    9. Genetic association of an LBP-1c/CP2/LSF gene polymorphism with late onset Alzheimer's disease. (PubMed id 11283204)1, 4 Taylor A.E....Rubinsztein D.C. (2001)
    10. Characterization of a family of related cellular transcription factors which can modulate human immunodeficiency virus type 1 transcription in vitro. (PubMed id 8114710)1, 2 Yoon J.-B.... Roeder R.G. (1994)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7024 HGNC: 11748 AceView: TFCP2 Ensembl:ENSG00000135457 euGenes: HUgn7024
    ECgene: TFCP2 H-InvDB: TFCP2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TFCP2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TFCP2 gene:
    Search GeneIP for patents involving TFCP2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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