Aliases for TFAP2D Gene
External Ids for TFAP2D Gene
Previous HGNC Symbols for TFAP2D Gene
Previous GeneCards Identifiers for TFAP2D Gene
GeneCards Summary for TFAP2D Gene
TFAP2D (Transcription Factor AP-2 Delta (Activating Enhancer Binding Protein 2 Delta)) is a Protein Coding gene. GO annotations related to this gene include sequence-specific DNA binding RNA polymerase II transcription factor activity and RNA polymerase II regulatory region sequence-specific DNA binding. An important paralog of this gene is TFAP2E.
UniProtKB/Swiss-Prot for TFAP2D Gene
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5-GCCNNNGGC-3 and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC (By similarity).