Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TEX45 Gene

Aliases for TEX45 Gene

  • Testis Expressed 45 2 3
  • C19orf45 3 4 5
  • Chromosome 19 Open Reading Frame 45 2 5
  • Uncharacterized Protein C19orf45 3

External Ids for TEX45 Gene

Previous HGNC Symbols for TEX45 Gene

  • C19orf45

Summaries for TEX45 Gene

GeneCards Summary for TEX45 Gene

TEX45 (Testis Expressed 45) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX45 Gene

Genomics for TEX45 Gene

Regulatory Elements for TEX45 Gene

Enhancers for TEX45 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G007498 0.3 FANTOM5 79.7 +5.8 5849 0.1 TEX45 PCP2 PNPLA6 EVI5L PEX11G ENSG00000267952
GH19G007424 0.9 ENCODE 17.5 -66.9 -66949 3.3 ELF3 ATF1 CREB3L1 SREBF2 RARA ZNF121 FOS CREM EGR2 SP3 ARHGEF18 TEX45 PEX11G CAMSAP3 GC19P007434 ENSG00000267852
GH19G007397 1.2 Ensembl ENCODE 11.2 -94.2 -94247 2.7 FOXA2 ARID4B SIN3A ZNF48 ZNF121 PPARG TBX21 KAT8 MIER3 GLIS1 TEX45 PEX11G NDUFA7 ENSG00000267852 GC19P007434
GH19G007188 1.2 Ensembl ENCODE dbSUPER 10.2 -303.9 -303944 1.6 CTCF SOX13 KLF1 CEBPG ZBTB40 ZNF121 ZFHX2 GATA2 FOS EGR2 ARHGEF18 PEX11G TEX45 CAMSAP3 RETN GC19P007214 GC19P007151
GH19G007394 1 ENCODE 11.2 -97.4 -97411 2.8 HNRNPUL1 PKNOX1 ARID4B SIN3A ZNF48 ETS1 ZNF121 GLIS2 ELK1 ZNF143 TEX45 PEX11G NDUFA7 ENSG00000267852 GC19P007434
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TEX45 on UCSC Golden Path with GeneCards custom track

Genomic Location for TEX45 Gene

Chromosome:
19
Start:
7,492,976 bp from pter
End:
7,515,233 bp from pter
Size:
22,258 bases
Orientation:
Plus strand

Genomic View for TEX45 Gene

Genes around TEX45 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX45 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX45 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX45 Gene

Proteins for TEX45 Gene

  • Protein details for TEX45 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NA69-CS045_HUMAN
    Recommended name:
    Uncharacterized protein C19orf45
    Protein Accession:
    Q8NA69
    Secondary Accessions:
    • Q8N115

    Protein attributes for TEX45 Gene

    Size:
    505 amino acids
    Molecular mass:
    57331 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH29824.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAH34779.1; Type=Erroneous initiation; Evidence={ECO:0000305};

neXtProt entry for TEX45 Gene

Post-translational modifications for TEX45 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TEX45 Gene

Domains & Families for TEX45 Gene

Protein Domains for TEX45 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX45: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TEX45 Gene

Function for TEX45 Gene

genes like me logo Genes that share phenotypes with TEX45: view

Animal Model Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TEX45 Gene

Localization for TEX45 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX45 gene
Compartment Confidence
mitochondrion 1
peroxisome 1
nucleus 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TEX45 Gene

Pathways & Interactions for TEX45 Gene

SuperPathways for TEX45 Gene

No Data Available

Interacting Proteins for TEX45 Gene

Gene Ontology (GO) - Biological Process for TEX45 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX45 Gene

Drugs & Compounds for TEX45 Gene

No Compound Related Data Available

Transcripts for TEX45 Gene

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX45 Gene

No ASD Table

Relevant External Links for TEX45 Gene

GeneLoc Exon Structure for
TEX45
ECgene alternative splicing isoforms for
TEX45

Expression for TEX45 Gene

NURSA nuclear receptor signaling pathways regulating expression of TEX45 Gene:

TEX45
No Expression Related Data Available

Primer Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX45 Gene

Orthologs for TEX45 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEX45 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf45 34
  • 99.21 (n)
C19orf45 35
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia C7H19orf45 34
  • 79 (n)
C19orf45 35
  • 67 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700019B03Rik 34 35
  • 69.38 (n)
Tex45 16
rat
(Rattus norvegicus)
Mammalia RGD1563425 34
  • 69.05 (n)
dog
(Canis familiaris)
Mammalia C19orf45 35
  • 59 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia C19orf45 35
  • 32 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia C19orf45 35
  • 28 (a)
OneToOne
chicken
(Gallus gallus)
Aves C28H19orf45 34
  • 48.56 (n)
C19orf45 35
  • 30 (a)
OneToOne
Species where no ortholog for TEX45 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX45 Gene

ENSEMBL:
Gene Tree for TEX45 (if available)
TreeFam:
Gene Tree for TEX45 (if available)

Paralogs for TEX45 Gene

No data available for Paralogs for TEX45 Gene

Variants for TEX45 Gene

Sequence variations from dbSNP and Humsavar for TEX45 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000103707 -- 7,499,189(+) TACCT(A/G)TTATC intron-variant
rs1000485092 -- 7,505,908(+) CCCCC(A/C/G)CGGGC intron-variant
rs1000545164 -- 7,499,960(+) TGTGT(A/G)TGTGT intron-variant
rs1000638630 -- 7,500,332(+) AGTCT(C/T)GCTCT intron-variant
rs1000836036 -- 7,505,553(+) GGAGT(C/G)GCACA nc-transcript-variant, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for TEX45 Gene

Variant ID Type Subtype PubMed ID
esv2751809 CNV gain 17911159
esv3367657 CNV insertion 20981092
esv3643587 CNV loss 21293372
nsv1060887 CNV gain 25217958
nsv2400 CNV insertion 18451855
nsv828416 CNV loss 20364138

Variation tolerance for TEX45 Gene

Residual Variation Intolerance Score: 91.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 19.57; 98.90% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX45 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX45

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX45 Gene

Disorders for TEX45 Gene

Relevant External Links for TEX45

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX45

No disorders were found for TEX45 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX45 Gene

Publications for TEX45 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 64
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64

Products for TEX45 Gene

Sources for TEX45 Gene

Content
Loading form....