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Aliases for TEX43 Gene

Aliases for TEX43 Gene

  • Testis Expressed 43 2 3 5
  • Testis Specific Expressed Gene 7 2 3
  • C5orf48 3 4
  • Testis-Expressed Sequence 43 Protein 3
  • Chromosome 5 Open Reading Frame 48 2
  • Testis-Expressed Protein 43 3
  • Tseg7 3

External Ids for TEX43 Gene

Previous HGNC Symbols for TEX43 Gene

  • C5orf48

Previous GeneCards Identifiers for TEX43 Gene

  • GC05P125969

Summaries for TEX43 Gene

GeneCards Summary for TEX43 Gene

TEX43 (Testis Expressed 43) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX43 Gene

Genomics for TEX43 Gene

Regulatory Elements for TEX43 Gene

Enhancers for TEX43 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH05G126367 1.8 FANTOM5 Ensembl ENCODE dbSUPER 51.6 -260.5 -260507 7.7 HNRNPUL1 PKNOX1 FOXA2 ATF1 MLX ARID4B DMAP1 ZNF48 YY1 SP5 TEX43 ENSG00000250602 GRAMD2B LOC101927514
GH05G126592 1.1 ENCODE 12.7 -37.4 -37351 3.1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 FOS ZNF263 SP3 ALDH7A1 RPLP1P7 TEX43 ENSG00000250602 GRAMD2B RNU6-290P
GH05G126543 1 ENCODE dbSUPER 11.2 -87.8 -87824 0.9 CTCF MXI1 FOXA2 SAP130 MLX MAX RAD21 NCOR1 ZNF143 HNF4G ALDH7A1 PHAX RPLP1P7 TEX43 ENSG00000250602 GRAMD2B GC05M126556 ENSG00000279118
GH05G126664 0.9 ENCODE 12.4 +33.2 33192 1.5 PKNOX1 ARNT FEZF1 ZNF2 ZNF121 TSHZ1 MYNN GLIS1 WT1 PRDM4 ALDH7A1 TEX43 RPLP1P7 PHAX BOLA3P3 LOC105379162
GH05G126591 0.5 ENCODE 12.1 -40.0 -39979 0.3 ZNF664 HDAC2 KDM1A TEX43 RPLP1P7 ENSG00000250602 GRAMD2B ALDH7A1 RNU6-290P
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TEX43 on UCSC Golden Path with GeneCards custom track

Genomic Location for TEX43 Gene

Chromosome:
5
Start:
126,631,722 bp from pter
End:
126,636,287 bp from pter
Size:
4,566 bases
Orientation:
Plus strand

Genomic View for TEX43 Gene

Genes around TEX43 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX43 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX43 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX43 Gene

Proteins for TEX43 Gene

  • Protein details for TEX43 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6ZNM6-TEX43_HUMAN
    Recommended name:
    Testis-expressed protein 43
    Protein Accession:
    Q6ZNM6

    Protein attributes for TEX43 Gene

    Size:
    134 amino acids
    Molecular mass:
    15452 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX43 Gene

Post-translational modifications for TEX43 Gene

No Post-translational modifications

Other Protein References for TEX43 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX43 Gene

Domains & Families for TEX43 Gene

Protein Domains for TEX43 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX43: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TEX43 Gene

Function for TEX43 Gene

genes like me logo Genes that share phenotypes with TEX43: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TEX43 Gene

Localization for TEX43 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX43 gene
Compartment Confidence
nucleus 2
cytosol 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TEX43 Gene

Pathways & Interactions for TEX43 Gene

SuperPathways for TEX43 Gene

No Data Available

Interacting Proteins for TEX43 Gene

Selected Interacting proteins: Q6ZNM6-TEX43_HUMAN for TEX43 Gene via IID

Gene Ontology (GO) - Biological Process for TEX43 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX43 Gene

Transcripts for TEX43 Gene

mRNA/cDNA for TEX43 Gene

(1) REFSEQ mRNAs :
(10) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX43 Gene

No ASD Table

Relevant External Links for TEX43 Gene

GeneLoc Exon Structure for
TEX43
ECgene alternative splicing isoforms for
TEX43

Expression for TEX43 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TEX43 Gene

mRNA differential expression in normal tissues according to GTEx for TEX43 Gene

This gene is overexpressed in Testis (x46.7).

NURSA nuclear receptor signaling pathways regulating expression of TEX43 Gene:

TEX43
genes like me logo Genes that share expression patterns with TEX43: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX43 Gene

Orthologs for TEX43 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEX43 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C5orf48 35
  • 100 (a)
OneToOne
TEX43 34
  • 99.75 (n)
cow
(Bos Taurus)
Mammalia TEX43 34
  • 90.23 (n)
C7H5orf48 35
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TEX43 34
  • 90.05 (n)
C5orf48 35
  • 77 (a)
OneToOne
mouse
(Mus musculus)
Mammalia 1700065I17Rik 34 35
  • 78.61 (n)
Tex43 16
rat
(Rattus norvegicus)
Mammalia RGD1561039 34
  • 78.46 (n)
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 55 (a)
OneToMany
-- 35
  • 52 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia C5orf48 35
  • 45 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 35 (a)
OneToOne
Species where no ortholog for TEX43 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX43 Gene

ENSEMBL:
Gene Tree for TEX43 (if available)
TreeFam:
Gene Tree for TEX43 (if available)

Paralogs for TEX43 Gene

No data available for Paralogs for TEX43 Gene

Variants for TEX43 Gene

Sequence variations from dbSNP and Humsavar for TEX43 Gene

SNP ID Clin Chr 05 pos Sequence Context AA Info Type
rs1000171953 -- 126,629,729(+) GTAAT(C/T)CCAGC upstream-variant-2KB
rs1000374163 -- 126,635,194(+) TATAT(A/G)TATGA intron-variant
rs1000596633 -- 126,632,276(+) AAAAA(A/C)AAAAA intron-variant
rs1000745299 -- 126,635,566(+) TCTTT(A/C)TGGTA intron-variant
rs1001294696 -- 126,630,551(+) GGTGG(A/C)ATACG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TEX43 Gene

Variant ID Type Subtype PubMed ID
esv3606679 CNV gain 21293372
esv3606685 CNV gain 21293372
nsv1030016 CNV gain 25217958
nsv462442 CNV gain 19166990
nsv599662 CNV gain 21841781

Variation tolerance for TEX43 Gene

Residual Variation Intolerance Score: 53.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.35; 7.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX43 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX43

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX43 Gene

Disorders for TEX43 Gene

Relevant External Links for TEX43

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX43

No disorders were found for TEX43 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX43 Gene

Publications for TEX43 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4 64
  2. The DNA sequence and comparative analysis of human chromosome 5. (PMID: 15372022) Schmutz J. … Rubin E.M. (Nature 2004) 4 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for TEX43 Gene

Sources for TEX43 Gene

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