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Aliases for TEX40 Gene

Aliases for TEX40 Gene

  • Testis Expressed 40 2 3 5
  • C11orf20 3 4
  • Testis-Expressed Sequence 40 Protein 3
  • Chromosome 11 Open Reading Frame 20 2

External Ids for TEX40 Gene

Previous HGNC Symbols for TEX40 Gene

  • C11orf20

Previous GeneCards Identifiers for TEX40 Gene

  • GC11P064069

Summaries for TEX40 Gene

GeneCards Summary for TEX40 Gene

TEX40 (Testis Expressed 40) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TEX40 Gene

  • May be involved in late spermatogenesis.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX40 Gene

Genomics for TEX40 Gene

Regulatory Elements for TEX40 Gene

Enhancers for TEX40 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11F064320 0.5 ENCODE 12.2 +22.7 22729 5.3 HDAC1 KLF17 NFXL1 RAD21 ZNF366 SCRT2 EGR2 ZNF263 ZBTB2 CEBPB PLCB3 LOC102723878 TEX40 ENSG00000207024 KCNK4 KCNK4-TEX40 BAD GPR137 ENSG00000257086 TRMT112
GH11F064347 0.6 ENCODE 11.5 +48.0 47991 1.9 BCOR KLF1 JUN CHD4 ZMYM3 MAX CEBPG ZNF366 POLR2A PATZ1 LOC102723878 MIR1237 PRDX5 TRMT112 ESRRA TEX40 ENSG00000207024 KCNK4 KCNK4-TEX40 BAD
GH11F064205 0.4 ENCODE 11.5 -92.8 -92796 4.4 HDGF PKNOX1 ARNT CREB3L1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF766 TRPT1 PLCB3 TRMT112 ZFPL1 ENSG00000257086 GPR137 BAD KCNK4 KCNK4-TEX40 ENSG00000207024
GH11F064299 0.4 ENCODE 0.8 -1.0 -1008 0.2 SUZ12 ENSG00000207024 TEX40
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TEX40 on UCSC Golden Path with GeneCards custom track

Promoters for TEX40 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001570763 909 601 HDAC1 ATF1 ARID4B SIN3A DMAP1 RAD21 RFX5 SLC30A9 ZNF143 CREM

Genomic Location for TEX40 Gene

64,300,391 bp from pter
64,304,770 bp from pter
4,380 bases
Plus strand

Genomic View for TEX40 Gene

Genes around TEX40 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX40 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX40 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX40 Gene

Proteins for TEX40 Gene

  • Protein details for TEX40 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Testis-expressed sequence 40 protein
    Protein Accession:

    Protein attributes for TEX40 Gene

    200 amino acids
    Molecular mass:
    22839 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX40 Gene

Post-translational modifications for TEX40 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX40 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX40 Gene

Domains & Families for TEX40 Gene

Protein Domains for TEX40 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX40: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TEX40 Gene

Function for TEX40 Gene

Molecular function for TEX40 Gene

UniProtKB/Swiss-Prot Function:
May be involved in late spermatogenesis.

Phenotypes for TEX40 Gene

MGI mutant phenotypes for TEX40:
inferred from 1 alleles
genes like me logo Genes that share phenotypes with TEX40: view

Animal Models for TEX40 Gene

MGI Knock Outs for TEX40:

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for TEX40 Gene

Localization for TEX40 Gene

Gene Ontology (GO) - Cellular Components for TEX40 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with TEX40: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for TEX40 Gene

Pathways & Interactions for TEX40 Gene

SuperPathways for TEX40 Gene

No Data Available

Interacting Proteins for TEX40 Gene

Gene Ontology (GO) - Biological Process for TEX40 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007140 male meiosis ISS --
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
genes like me logo Genes that share ontologies with TEX40: view

No data available for Pathways by source and SIGNOR curated interactions for TEX40 Gene

Transcripts for TEX40 Gene

mRNA/cDNA for TEX40 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TEX40 Gene

Testis expressed 40:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX40 Gene

No ASD Table

Relevant External Links for TEX40 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TEX40 Gene

mRNA expression in normal human tissues for TEX40 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TEX40 Gene

This gene is overexpressed in Testis (x47.3).

NURSA nuclear receptor signaling pathways regulating expression of TEX40 Gene:


SOURCE GeneReport for Unigene cluster for TEX40 Gene:

genes like me logo Genes that share expression patterns with TEX40: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TEX40 Gene

Orthologs for TEX40 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TEX40 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TEX40 34 35
  • 99.5 (n)
(Canis familiaris)
Mammalia TEX40 34
  • 77.15 (n)
(Bos Taurus)
Mammalia TEX40 34
  • 71.6 (n)
(Mus musculus)
Mammalia Tex40 34 16 35
  • 65.43 (n)
Species where no ortholog for TEX40 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX40 Gene

Gene Tree for TEX40 (if available)
Gene Tree for TEX40 (if available)

Paralogs for TEX40 Gene

No data available for Paralogs for TEX40 Gene

Variants for TEX40 Gene

Sequence variations from dbSNP and Humsavar for TEX40 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs111486531 -- 64,303,837(+) CCTCC(A/G)GAGTA nc-transcript-variant, upstream-variant-2KB, reference, missense
rs111651235 -- 64,300,515(+) TTACT(C/G)AGCCT intron-variant, downstream-variant-500B
rs111868559 -- 64,303,141(+) TGATC(C/T)GCCCA intron-variant
rs11231746 -- 64,303,468(+) CTTTT(C/T)TCTCT intron-variant
rs112784059 -- 64,303,384(+) TCTCT(A/G)AAGGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TEX40 Gene

Variant ID Type Subtype PubMed ID
dgv1963n54 CNV loss 21841781
nsv357 CNV insertion 18451855
nsv469961 CNV loss 18288195
nsv832186 CNV loss 17160897
nsv951010 CNV deletion 24416366

Variation tolerance for TEX40 Gene

Gene Damage Index Score: 3.96; 59.85% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX40 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX40 Gene

Disorders for TEX40 Gene

Relevant External Links for TEX40

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TEX40 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX40 Gene

Publications for TEX40 Gene

  1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 3 4 64
  2. Low frequency of ESRRA-C11orf20 fusion gene in ovarian carcinomas. (PMID: 24504521) Micci F. … Heim S. (PLoS Biol. 2014) 3 64
  3. ESRRA-C11orf20 is a recurrent gene fusion in serous ovarian carcinoma. (PMID: 21949640) Salzman J. … Brown P.O. (PLoS Biol. 2011) 3 64
  4. A strategy for precise and large scale identification of core fucosylated glycoproteins. (PMID: 19139490) Jia W. … Qian X.H. (Mol. Cell. Proteomics 2009) 4 64
  5. The LIFEdb database in 2006. (PMID: 16381901) Mehrle A. … Wiemann S. (Nucleic Acids Res. 2006) 3 64

Products for TEX40 Gene

Sources for TEX40 Gene

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