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Aliases for TEX37 Gene

Aliases for TEX37 Gene

  • Testis Expressed 37 2 3 5
  • Testis-Specific Conserved Protein Of 21 KDa 3 4
  • Testis-Specific Conserved Gene 21kDa 2 3
  • C2orf51 3 4
  • TSC21 3 4
  • Testis Tissue Sperm-Binding Protein Li 93mP 3
  • Testis-Expressed Sequence 37 Protein 3
  • Chromosome 2 Open Reading Frame 51 2
  • Protein TSC21 3

External Ids for TEX37 Gene

Previous HGNC Symbols for TEX37 Gene

  • C2orf51

Previous GeneCards Identifiers for TEX37 Gene

  • GC02P088825

Summaries for TEX37 Gene

GeneCards Summary for TEX37 Gene

TEX37 (Testis Expressed 37) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX37 Gene

Genomics for TEX37 Gene

Regulatory Elements for TEX37 Gene

Enhancers for TEX37 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around TEX37 on UCSC Golden Path with GeneCards custom track

Genomic Location for TEX37 Gene

Chromosome:
2
Start:
88,524,317 bp from pter
End:
88,529,585 bp from pter
Size:
5,269 bases
Orientation:
Plus strand

Genomic View for TEX37 Gene

Genes around TEX37 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX37 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX37 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX37 Gene

Proteins for TEX37 Gene

  • Protein details for TEX37 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96LM6-TEX37_HUMAN
    Recommended name:
    Testis-expressed sequence 37 protein
    Protein Accession:
    Q96LM6

    Protein attributes for TEX37 Gene

    Size:
    180 amino acids
    Molecular mass:
    20615 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX37 Gene

Post-translational modifications for TEX37 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX37 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX37 Gene

Domains & Families for TEX37 Gene

Protein Domains for TEX37 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX37 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX37: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEX37 Gene

Function for TEX37 Gene

Gene Ontology (GO) - Molecular Function for TEX37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with TEX37: view
genes like me logo Genes that share phenotypes with TEX37: view

Animal Models for TEX37 Gene

MGI Knock Outs for TEX37:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for TEX37 Gene

Localization for TEX37 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEX37 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TEX37 Gene COMPARTMENTS Subcellular localization image for TEX37 gene
Compartment Confidence
nucleus 4
extracellular 2
cytosol 1
mitochondrion 1

Gene Ontology (GO) - Cellular Components for TEX37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with TEX37: view

Pathways & Interactions for TEX37 Gene

SuperPathways for TEX37 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TEX37 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX37 Gene

Drugs & Compounds for TEX37 Gene

No Compound Related Data Available

Transcripts for TEX37 Gene

mRNA/cDNA for TEX37 Gene

(4) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(22) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TEX37 Gene

Testis expressed 37:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX37 Gene

No ASD Table

Relevant External Links for TEX37 Gene

GeneLoc Exon Structure for
TEX37
ECgene alternative splicing isoforms for
TEX37

Expression for TEX37 Gene

mRNA expression in normal human tissues for TEX37 Gene

mRNA differential expression in normal tissues according to GTEx for TEX37 Gene

This gene is overexpressed in Testis (x52.7).

NURSA nuclear receptor signaling pathways regulating expression of TEX37 Gene:

TEX37

SOURCE GeneReport for Unigene cluster for TEX37 Gene:

Hs.132104

mRNA Expression by UniProt/SwissProt for TEX37 Gene:

Q96LM6-TEX37_HUMAN
Tissue specificity: Testis-specific.
genes like me logo Genes that share expression patterns with TEX37: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for TEX37 Gene

Orthologs for TEX37 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TEX37 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TEX37 34
  • 78.52 (n)
  • 72.78 (a)
TEX37 35
  • 73 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TEX37 34
  • 81.48 (n)
  • 71.67 (a)
TEX37 35
  • 72 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tex37 34
  • 77.41 (n)
  • 70 (a)
Tex37 16
Tex37 35
  • 70 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TEX37 34
  • 98.89 (n)
  • 97.22 (a)
TEX37 35
  • 97 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tex37 34
  • 76.54 (n)
  • 69.27 (a)
Species where no ortholog for TEX37 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX37 Gene

ENSEMBL:
Gene Tree for TEX37 (if available)
TreeFam:
Gene Tree for TEX37 (if available)

Paralogs for TEX37 Gene

No data available for Paralogs for TEX37 Gene

Variants for TEX37 Gene

Sequence variations from dbSNP and Humsavar for TEX37 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs35750657 - 88,526,447(-) ATAGT(C/T)GACCA reference, missense
rs6709903 -- 88,522,386(+) ggagg(C/T)tagga upstream-variant-2KB
rs6711356 -- 88,526,677(+) ttttt(C/T)ttttt intron-variant
rs6720599 -- 88,530,063(+) TACTG(C/T)TTTAA downstream-variant-500B
rs7598916 -- 88,527,080(+) CAGAC(A/C/T)GCTTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TEX37 Gene

Variant ID Type Subtype PubMed ID
dgv61n16 CNV deletion 17901297
dgv6947n54 CNV gain 21841781
esv24191 CNV gain 19812545
esv3591591 CNV loss 21293372
esv3591592 CNV gain 21293372
nsv1072005 CNV deletion 25765185
nsv1130752 CNV deletion 24896259
nsv1148611 CNV deletion 26484159
nsv458596 CNV gain 19166990
nsv470476 CNV gain 18288195
nsv582383 CNV gain 21841781
nsv582384 CNV loss 21841781
nsv582386 CNV loss 21841781
nsv582387 CNV gain 21841781

Variation tolerance for TEX37 Gene

Residual Variation Intolerance Score: 84.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.28; 62.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX37 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX37

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX37 Gene

Disorders for TEX37 Gene

Relevant External Links for TEX37

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX37

No disorders were found for TEX37 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX37 Gene

Publications for TEX37 Gene

  1. Identification and characteristics of a novel testis-specific gene, Tsc21, in mice and human. (PMID: 17091336) Yu Z. … Cai Z. (Mol. Biol. Rep. 2007) 2 3 4 65
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 65
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 65
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3 65
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 65

Products for TEX37 Gene

Sources for TEX37 Gene

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