Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TEX37 Gene

Aliases for TEX37 Gene

  • Testis Expressed 37 2 3 5
  • Testis-Specific Conserved Protein Of 21 KDa 3 4
  • Testis-Specific Conserved Gene 21kDa 2 3
  • C2orf51 3 4
  • TSC21 3 4
  • Testis Tissue Sperm-Binding Protein Li 93mP 3
  • Testis-Expressed Sequence 37 Protein 3
  • Chromosome 2 Open Reading Frame 51 2
  • Protein TSC21 3

External Ids for TEX37 Gene

Previous HGNC Symbols for TEX37 Gene

  • C2orf51

Previous GeneCards Identifiers for TEX37 Gene

  • GC02P088825

Summaries for TEX37 Gene

GeneCards Summary for TEX37 Gene

TEX37 (Testis Expressed 37) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX37 Gene

Genomics for TEX37 Gene

Regulatory Elements for TEX37 Gene

Enhancers for TEX37 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F088549 0.8 Ensembl ENCODE 33.9 +25.7 25652 1.0 ZNF263 GATA3 KDM1A EZH2 TEX37 ANKRD36BP2 GC02P088558 LOC101928371
GH02F088291 0.3 FANTOM5 47.8 -233.1 -233109 0.3 TEX37 GC02P088321 RNY4P15 GC02M088230
GH02F088442 0.6 ENCODE 18.2 -80.8 -80765 2.3 ZNF316 MAFG POU5F1 NFE2 EMSY MAFK TEX37 RNU6-1007P LOC101928403 FOXI3 ENSG00000224291
GH02F088626 1.2 ENCODE 8.6 +103.5 103486 3.7 HDGF PKNOX1 ARNT CREB3L1 WRNIP1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 LOC101928403 LOC730268 RPIA TEX37 ANKRD36BP2 EIF2AK3 GC02M088650
GH02F088503 0.6 FANTOM5 12.9 -20.6 -20561 0.4 POLR2H PKNOX1 NFYB GTF2A2 TEX37 EIF2AK3 FOXI3 PIR49195 GC02M088487
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TEX37 on UCSC Golden Path with GeneCards custom track

Genomic Location for TEX37 Gene

Chromosome:
2
Start:
88,524,317 bp from pter
End:
88,529,585 bp from pter
Size:
5,269 bases
Orientation:
Plus strand

Genomic View for TEX37 Gene

Genes around TEX37 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX37 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX37 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX37 Gene

Proteins for TEX37 Gene

  • Protein details for TEX37 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96LM6-TEX37_HUMAN
    Recommended name:
    Testis-expressed sequence 37 protein
    Protein Accession:
    Q96LM6

    Protein attributes for TEX37 Gene

    Size:
    180 amino acids
    Molecular mass:
    20615 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX37 Gene

Post-translational modifications for TEX37 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX37 Gene

No data available for DME Specific Peptides for TEX37 Gene

Domains & Families for TEX37 Gene

Protein Domains for TEX37 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX37 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX37: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEX37 Gene

Function for TEX37 Gene

Gene Ontology (GO) - Molecular Function for TEX37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 16189514
genes like me logo Genes that share ontologies with TEX37: view
genes like me logo Genes that share phenotypes with TEX37: view

Animal Models for TEX37 Gene

MGI Knock Outs for TEX37:

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for TEX37 Gene

Localization for TEX37 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEX37 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX37 gene
Compartment Confidence
nucleus 4
extracellular 2
mitochondrion 1
cytosol 1

Gene Ontology (GO) - Cellular Components for TEX37 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
genes like me logo Genes that share ontologies with TEX37: view

Pathways & Interactions for TEX37 Gene

SuperPathways for TEX37 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TEX37 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX37 Gene

Transcripts for TEX37 Gene

mRNA/cDNA for TEX37 Gene

(4) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(22) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TEX37 Gene

Testis expressed 37:
Representative Sequences:

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX37 Gene

No ASD Table

Relevant External Links for TEX37 Gene

GeneLoc Exon Structure for
TEX37
ECgene alternative splicing isoforms for
TEX37

Expression for TEX37 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TEX37 Gene

mRNA differential expression in normal tissues according to GTEx for TEX37 Gene

This gene is overexpressed in Testis (x52.7).

NURSA nuclear receptor signaling pathways regulating expression of TEX37 Gene:

TEX37

SOURCE GeneReport for Unigene cluster for TEX37 Gene:

Hs.132104

mRNA Expression by UniProt/SwissProt for TEX37 Gene:

Q96LM6-TEX37_HUMAN
Tissue specificity: Testis-specific.
genes like me logo Genes that share expression patterns with TEX37: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for TEX37 Gene

Orthologs for TEX37 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TEX37 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TEX37 34 35
  • 98.89 (n)
dog
(Canis familiaris)
Mammalia TEX37 34 35
  • 81.48 (n)
cow
(Bos Taurus)
Mammalia TEX37 34 35
  • 78.52 (n)
mouse
(Mus musculus)
Mammalia Tex37 34 16 35
  • 77.41 (n)
rat
(Rattus norvegicus)
Mammalia Tex37 34
  • 76.54 (n)
Species where no ortholog for TEX37 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX37 Gene

ENSEMBL:
Gene Tree for TEX37 (if available)
TreeFam:
Gene Tree for TEX37 (if available)

Paralogs for TEX37 Gene

No data available for Paralogs for TEX37 Gene

Variants for TEX37 Gene

Sequence variations from dbSNP and Humsavar for TEX37 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10451633 -- 88,523,676(+) tgacc(A/G)gctta upstream-variant-2KB
rs10451634 -- 88,523,927(+) caccc(A/G)gctaa upstream-variant-2KB
rs10451635 -- 88,524,176(+) tgttg(C/T)gaacg upstream-variant-2KB
rs10451670 -- 88,523,720(+) aggtt(C/T)atcca upstream-variant-2KB
rs10451671 -- 88,523,991(+) gaact(C/T)ctgac upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TEX37 Gene

Variant ID Type Subtype PubMed ID
nsv582387 CNV gain 21841781
nsv582386 CNV loss 21841781
nsv582384 CNV loss 21841781
nsv582383 CNV gain 21841781
nsv470476 CNV gain 18288195
nsv458596 CNV gain 19166990
nsv1148611 CNV deletion 26484159
nsv1130752 CNV deletion 24896259
nsv1072005 CNV deletion 25765185
esv3591592 CNV gain 21293372
esv3591591 CNV loss 21293372
esv24191 CNV gain 19812545
dgv6947n54 CNV gain 21841781
dgv61n16 CNV deletion 17901297

Variation tolerance for TEX37 Gene

Residual Variation Intolerance Score: 84.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.28; 62.63% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX37 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX37

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX37 Gene

Disorders for TEX37 Gene

Relevant External Links for TEX37

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX37

No disorders were found for TEX37 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX37 Gene

Publications for TEX37 Gene

  1. Identification and characteristics of a novel testis-specific gene, Tsc21, in mice and human. (PMID: 17091336) Yu Z. … Cai Z. (Mol. Biol. Rep. 2007) 2 3 4 64
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3 64
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3 64
  4. Towards a proteome-scale map of the human protein-protein interaction network. (PMID: 16189514) Rual J.F. … Vidal M. (Nature 2005) 3 64
  5. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 4 64

Products for TEX37 Gene

Sources for TEX37 Gene

Content
Loading form....