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Aliases for TEX35 Gene

Aliases for TEX35 Gene

  • Testis Expressed 35 2 3 5
  • Testis-Specific Conserved Gene 24kDa 2 3
  • C1orf49 3 4
  • Testis-Expressed Sequence 35 Protein 3
  • Chromosome 1 Open Reading Frame 49 2
  • Testis-Expressed Protein 35 3
  • TSC24 3

External Ids for TEX35 Gene

Previous HGNC Symbols for TEX35 Gene

  • C1orf49

Previous GeneCards Identifiers for TEX35 Gene

  • GC01P178484

Summaries for TEX35 Gene

GeneCards Summary for TEX35 Gene

TEX35 (Testis Expressed 35) is a Protein Coding gene.

Gene Wiki entry for TEX35 Gene

Additional gene information for TEX35 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX35 Gene

Genomics for TEX35 Gene

Regulatory Elements for TEX35 Gene

Enhancers for TEX35 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H178540 1.6 FANTOM5 ENCODE dbSUPER 16.4 +29.9 29922 5 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 FOS DEK TEX35 C1orf220 RALGPS2 GC01P178561
GH01H178603 1.7 FANTOM5 Ensembl ENCODE dbSUPER 14.6 +96.2 96166 10 PKNOX1 NFIB BATF RAD21 RFX5 ZNF207 ATF7 FOS RUNX3 IKZF2 RALGPS2 TEX35 C1orf220 TOR3A GC01P178598 GC01M178650
GH01H178530 1.2 Ensembl ENCODE 14.9 +17.2 17170 1 PKNOX1 FOXA2 ARID4B YY1 GLIS2 FOS DEK SP3 MXD4 TSHZ1 TEX35 ENSG00000201791 LOC105371631
GH01H178580 1.2 FANTOM5 ENCODE dbSUPER 14.7 +68.4 68411 1 NFIB EBF1 RELA SP1 LCORL NFIC POLR2A EED RUNX3 IKZF2 TEX35 C1orf220 RALGPS2 LOC105371632 GC01P178598
GH01H178536 1.2 Ensembl ENCODE 14.1 +24.9 24886 3 TBP PKNOX1 FOXA2 KLF17 SIN3A THRB RAD21 RARA RFX5 YY1 TEX35 C1orf220 GC01M178539 LOC105371631
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TEX35 on UCSC Golden Path with GeneCards custom track

Genomic Location for TEX35 Gene

Chromosome:
1
Start:
178,513,077 bp from pter
End:
178,548,602 bp from pter
Size:
35,526 bases
Orientation:
Plus strand

Genomic View for TEX35 Gene

Genes around TEX35 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX35 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX35 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX35 Gene

Proteins for TEX35 Gene

  • Protein details for TEX35 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T0J7-TEX35_HUMAN
    Recommended name:
    Testis-expressed protein 35
    Protein Accession:
    Q5T0J7
    Secondary Accessions:
    • Q5T0J8
    • Q5T0J9
    • Q8IYU6
    • Q8N7Z1
    • Q8NA15
    • Q9H0Q7

    Protein attributes for TEX35 Gene

    Size:
    233 amino acids
    Molecular mass:
    26518 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TEX35 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TEX35 Gene

Post-translational modifications for TEX35 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TEX35 Gene

Domains & Families for TEX35 Gene

Gene Families for TEX35 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for TEX35 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX35 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX35: view

No data available for UniProtKB/Swiss-Prot for TEX35 Gene

Function for TEX35 Gene

Phenotypes From GWAS Catalog for TEX35 Gene

genes like me logo Genes that share phenotypes with TEX35: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TEX35 Gene

Localization for TEX35 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX35 gene
Compartment Confidence
nucleus 5
cytoskeleton 4
plasma membrane 3
cytosol 3

Gene Ontology (GO) - Cellular Components for TEX35 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus ISS --
GO:0015630 microtubule cytoskeleton IDA --
genes like me logo Genes that share ontologies with TEX35: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for TEX35 Gene

Pathways & Interactions for TEX35 Gene

SuperPathways for TEX35 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TEX35 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX35 Gene

Drugs & Compounds for TEX35 Gene

No Compound Related Data Available

Transcripts for TEX35 Gene

Unigene Clusters for TEX35 Gene

Testis expressed 35:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX35 Gene

No ASD Table

Relevant External Links for TEX35 Gene

GeneLoc Exon Structure for
TEX35
ECgene alternative splicing isoforms for
TEX35

Expression for TEX35 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TEX35 Gene

mRNA differential expression in normal tissues according to GTEx for TEX35 Gene

This gene is overexpressed in Testis (x50.6).

Protein differential expression in normal tissues from HIPED for TEX35 Gene

This gene is overexpressed in Plasma (54.5) and Frontal cortex (14.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TEX35 Gene



Protein tissue co-expression partners for TEX35 Gene

NURSA nuclear receptor signaling pathways regulating expression of TEX35 Gene:

TEX35

SOURCE GeneReport for Unigene cluster for TEX35 Gene:

Hs.534501

mRNA Expression by UniProt/SwissProt for TEX35 Gene:

Q5T0J7-TEX35_HUMAN
Tissue specificity: Testis-specific.

Evidence on tissue expression from TISSUES for TEX35 Gene

  • Nervous system(4.2)
genes like me logo Genes that share expression patterns with TEX35: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX35 Gene

Orthologs for TEX35 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TEX35 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TEX35 33 34
  • 98.64 (n)
dog
(Canis familiaris)
Mammalia LOC610944 33
  • 85.07 (n)
TEX35 34
  • 65 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TEX35 33 34
  • 81.67 (n)
rat
(Rattus norvegicus)
Mammalia Tex35 33
  • 77.24 (n)
mouse
(Mus musculus)
Mammalia Tex35 33 16 34
  • 74.79 (n)
oppossum
(Monodelphis domestica)
Mammalia TEX35 34
  • 44 (a)
OneToOne
Species where no ortholog for TEX35 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX35 Gene

ENSEMBL:
Gene Tree for TEX35 (if available)
TreeFam:
Gene Tree for TEX35 (if available)

Paralogs for TEX35 Gene

(1) SIMAP similar genes for TEX35 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with TEX35: view

No data available for Paralogs for TEX35 Gene

Variants for TEX35 Gene

Sequence variations from dbSNP and Humsavar for TEX35 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000231806 -- 178,518,916(+) AGTCA(C/T)GAAGT intron-variant
rs1000271538 -- 178,520,680(+) CCCTT(A/T)GAAGA reference, stop-gained
rs1000281580 -- 178,520,850(+) GATCC(C/T)CTTCA reference, synonymous-codon
rs1000708178 -- 178,518,720(+) TCTGT(A/G)CTGTC intron-variant
rs1001302625 -- 178,511,540(+) CCAAA(G/T)GATAA intron-variant, downstream-variant-500B, upstream-variant-2KB

Variation tolerance for TEX35 Gene

Residual Variation Intolerance Score: 88.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.63; 65.56% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX35 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX35

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TEX35 Gene

Disorders for TEX35 Gene

Relevant External Links for TEX35

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX35

No disorders were found for TEX35 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX35 Gene

Publications for TEX35 Gene

  1. Identification and characteristics of a novel testis-specific gene, Tsc24, in human and mice. (PMID: 17077512) Tang A … Cai Z (Biological & pharmaceutical bulletin 2006) 2 3 4 60
  2. Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S … Poustka A (Genome research 2001) 2 3 4 60
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 60
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60

Products for TEX35 Gene

Sources for TEX35 Gene

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