TEX35 Gene
protein-coding GIFtS: 35
GCID: GC01P178484
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testis expressed 35(Previous name: chromosome 1 open reading frame 49 )
(Previous symbol: C1orf49)
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Aliases
for TEX35 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Testis Expressed 351 2 | | Chromosome 1 Open Reading Frame 491 | | C1orf491 2 3 | | Testis-Expressed Sequence 35 Protein2 | | TSC241 2 | | Testis-Specific Conserved Gene 24kDa2 | | DKFZP564J0471 | | |
Export aliases for TEX35 gene to outside databases |
Summaries
for TEX35 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Gene Wiki entry for TEX35 (C1orf49)
|
Genomic Views
for TEX35 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 Search SABiosciences Regulatory transcription factor binding sites for TEX35
Other transcription factors
Search SABiosciences Chromatin IP Primers for TEX35
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX35 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q25.2 Ensembl cytogenetic band: 1q25.2 HGNC cytogenetic band: 1q25.2TEX35 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P178484: view genomic region
(about GC identifiers)
Start:
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178,482,212 bp from pter |
End:
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178,517,734 bp from pter |
Size:
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35,523 bases |
Orientation:
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plus strand |
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Proteins
for TEX35 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TEX35_HUMAN, Q5T0J7 (See
protein sequence)Recommended Name: Testis-expressed sequence 35 protein Size: 233 amino acids; 26518 Da
Secondary accessions: Q5T0J8 Q5T0J9 Q8IYU6 Q8N7Z1 Q8NA15 Q9H0Q7Alternative splicing: 5 isoforms: Q5T0J7-1 Q5T0J7-2 Q5T0J7-3 Q5T0J7-4 Q5T0J7-5 Explore the universe of human proteins at neXtProt for TEX35: NX_Q5T0J7
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5T0J7
TEX35 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001164193.1 NP_001164194.1 NP_001164195.1 NP_115502.2
ENSEMBL proteins: ENSP00000323795 ENSP00000356615 ENSP00000356614 ENSP00000356613 ENSP00000430720 ENSP00000356611 ENSP00000413991 ENSP00000258298
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
ISS | -- | | GO:0015630 | microtubule cytoskeleton |
IDA | -- |
TEX35 for ontologies About GeneDecksing
TEX35 Antibody Products:
Assay Products for TEX35: |
Protein
Domains /
Families
for TEX35 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q5T0J7 |
Function
for TEX35 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX35 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX35 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript Custom all cDNA clones Services for TEX35 | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX35 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX35 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX35 |
|
Pathways & Interactions
for TEX35 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEX35
|
Drugs & Compounds
for TEX35 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TEX35
Search CenterWatch for drugs/clinical trials and news about TEX35
|
Transcripts
for TEX35 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TEX35 gene (4 alternative transcripts): NM_001170722.1 NM_001170723.1 NM_001170724.1 NM_032126.4 Unigene Cluster for TEX35: Testis expressed 35 Hs.534501 [show with all ESTs]Unigene Representative Sequence: BM5637198 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000319416(uc001glt.2) ENST00000367643(uc021pfd.1) ENST00000367642
ENST00000367641(uc001glu.1) ENST00000419909(uc001glv.1) ENST00000367639(uc021pfe.1 uc001glw.2)
ENST00000442872 ENST00000258298
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX35 (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX35 (see all 5)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript Custom all cDNA clones Services for TEX35 | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX35 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX35 |
Additional cDNA sequence: AL136694.1 BC034972.2 7 DOTS entries: DT.100749676 DT.100749677 DT.95160899 DT.40205058 DT.95160902 DT.70101845 DT.100021195 24/34 AceView cDNA sequences (see all 34): AK093269 AX748023 AI240606 CK902294 BX359643 BM563719 AK092849 NM_207467 NM_032126 BQ778206 AI692881 BG719876 BG772571 AI762835 BI464425 AX747765 BI825610 BI825350 BG773295 AW340027 AL136694 BE041517 BC034972 AA383469
GeneLoc Exon Structure
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Expression
for TEX35 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| See probesets specificity/sensitivity at GeneAnnot
CGAP TAG: --
See TEX35 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TEX35
SOURCE GeneReport for Unigene cluster: Hs.534501
UniProtKB/Swiss-Prot: TEX35_HUMAN, Q5T0J7Tissue specificity: Testis-specific
SABiosciences Custom PCR Arrays for TEX35
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX35
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TEX35 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX35 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX35 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX35 |
Orthologs
for TEX35 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for TEX35 gene from 1/6 species (see all 6) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Tex351 , 5 |
RIKEN cDNA 1700057K13 gene5
testis expressed 351 |
74.24(n)1
60.61(a)1 |
|
1 (67.97 cM)5
734351 NM_028540.21 NP_082816.11
1570991485 |
ENSEMBL Gene Tree for TEX35 (if available)
TreeFam Gene Tree for TEX35 (if available) |
Paralogs
for TEX35 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TEX35 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TEX35 (178482212 - 178517734 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TEX35: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for TEX35 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for TEX35 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TEX35 gene, integrated from 9 sources (see all 11):
(articles sorted by number of sources associating them with TEX35) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification and characteristics of a novel testis-specific gene, Tsc24, in human and mice. (PubMed id 17077512)1, 2, 3 Tang A....Cai Z. (2006)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
- The LIFEdb database in 2006. (PubMed id 16381901)1 Mehrle A....Wiemann S. (2006)
- From ORFeome to biology: a functional genomics pipeline. (PubMed id 15489336)1 Wiemann S....Poustka A. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. (PubMed id 11256614)1 Simpson J.C.... Wiemann S. (2000)
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External Searches for TEX35 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TEX35 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TEX35 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TEX35 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TEX35 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TEX35 gene:
Search GeneIP for patents involving TEX35
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TEX35 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TEX35 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TEX35 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX35 | | | OriGene Protein Over-expression Lysate for TEX35 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TEX35 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX35 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX35 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TEX35 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TEX35 | | OriGene Custom Protein Services for TEX35 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TEX35 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX35 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX35 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEX35 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX35 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX35 |
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| | | | Search Tocris compounds for TEX35 |
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 | | | TEX35 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX35 |
|  |  |  | | | | ThermoFisher Antibody for TEX35 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX35 |
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