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Aliases for TEX35 Gene

Aliases for TEX35 Gene

  • Testis Expressed 35 2 3
  • Testis-Specific Conserved Gene 24kDa 2 3
  • C1orf49 3 4
  • Chromosome 1 Open Reading Frame 49 2
  • TSC24 3
  • Tex35 4

External Ids for TEX35 Gene

Previous HGNC Symbols for TEX35 Gene

  • C1orf49

Previous GeneCards Identifiers for TEX35 Gene

  • GC01P178484

Summaries for TEX35 Gene

GeneCards Summary for TEX35 Gene

TEX35 (Testis Expressed 35) is a Protein Coding gene.

Gene Wiki entry for TEX35 Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX35 Gene

Genomics for TEX35 Gene

Genomic Location for TEX35 Gene

Chromosome:
1
Start:
178,513,077 bp from pter
End:
178,548,602 bp from pter
Size:
35,526 bases
Orientation:
Plus strand

Genomic View for TEX35 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TEX35 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX35 Gene

No data available for Regulatory Elements for TEX35 Gene

Proteins for TEX35 Gene

  • Protein details for TEX35 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T0J7-TEX35_HUMAN
    Recommended name:
    Testis-expressed sequence 35 protein
    Protein Accession:
    Q5T0J7
    Secondary Accessions:
    • Q5T0J8
    • Q5T0J9
    • Q8IYU6
    • Q8N7Z1
    • Q8NA15
    • Q9H0Q7

    Protein attributes for TEX35 Gene

    Size:
    233 amino acids
    Molecular mass:
    26518 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TEX35 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TEX35 Gene

Proteomics data for TEX35 Gene at MOPED

Post-translational modifications for TEX35 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TEX35 Gene

Domains & Families for TEX35 Gene

Protein Domains for TEX35 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX35 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX35: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEX35 Gene

Function for TEX35 Gene

Phenotypes for TEX35 Gene

genes like me logo Genes that share phenotypes with TEX35: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TEX35

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targets and HOMER Transcription for TEX35 Gene

Localization for TEX35 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TEX35 Gene COMPARTMENTS Subcellular localization image for TEX35 gene
Compartment Confidence
cytoskeleton 4
nucleus 4
cytosol 3
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TEX35 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus ISS --
GO:0015630 microtubule cytoskeleton IDA --
genes like me logo Genes that share ontologies with TEX35: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TEX35 Gene

Pathways & Interactions for TEX35 Gene

SuperPathways for TEX35 Gene

No Data Available

Interacting Proteins for TEX35 Gene

Gene Ontology (GO) - Biological Process for TEX35 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX35 Gene

Drugs & Compounds for TEX35 Gene

No Compound Related Data Available

Transcripts for TEX35 Gene

Unigene Clusters for TEX35 Gene

Testis expressed 35:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TEX35

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX35 Gene

No ASD Table

Relevant External Links for TEX35 Gene

GeneLoc Exon Structure for
TEX35
ECgene alternative splicing isoforms for
TEX35

Expression for TEX35 Gene

mRNA expression in normal human tissues for TEX35 Gene

mRNA differential expression in normal tissues according to GTEx for TEX35 Gene

This gene is overexpressed in Testis (x50.6).

Protein differential expression in normal tissues from HIPED for TEX35 Gene

This gene is overexpressed in Plasma (54.5) and Frontal cortex (14.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TEX35 Gene



SOURCE GeneReport for Unigene cluster for TEX35 Gene Hs.534501

mRNA Expression by UniProt/SwissProt for TEX35 Gene

Q5T0J7-TEX35_HUMAN
Tissue specificity: Testis-specific.
genes like me logo Genes that share expression patterns with TEX35: view

Protein tissue co-expression partners for TEX35 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for TEX35 Gene

Orthologs for TEX35 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TEX35 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TEX35 35
  • 81.67 (n)
  • 70.14 (a)
TEX35 36
  • 71 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC610944 35
  • 85.07 (n)
  • 77.08 (a)
TEX35 36
  • 65 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tex35 35
  • 74.79 (n)
  • 60.41 (a)
Tex35 16
Tex35 36
  • 57 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TEX35 35
  • 98.64 (n)
  • 97.45 (a)
TEX35 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tex35 35
  • 77.24 (n)
  • 62.9 (a)
oppossum
(Monodelphis domestica)
Mammalia TEX35 36
  • 44 (a)
OneToOne
Species with no ortholog for TEX35:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX35 Gene

ENSEMBL:
Gene Tree for TEX35 (if available)
TreeFam:
Gene Tree for TEX35 (if available)

Paralogs for TEX35 Gene

(1) SIMAP similar genes for TEX35 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with TEX35: view

No data available for Paralogs for TEX35 Gene

Variants for TEX35 Gene

Sequence variations from dbSNP and Humsavar for TEX35 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs3813636 -- 178,520,843(+) CTCAC(C/G/T)GGATC missense, reference
rs3813637 -- 178,522,545(+) AAGGA(C/G)GAGGA intron-variant, utr-variant-3-prime
rs4387136 -- 178,519,459(+) TTTTG(A/G)CTCTG intron-variant
rs7527160 -- 178,523,312(+) tacgc(A/T)gcagt synonymous-codon, reference
rs7527363 -- 178,523,500(+) ATAAA(C/T)ATTTA utr-variant-3-prime

Variation tolerance for TEX35 Gene

Residual Variation Intolerance Score: 88.63% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.63; 65.56% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX35 Gene

HapMap Linkage Disequilibrium report
TEX35

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TEX35 Gene

Disorders for TEX35 Gene

Relevant External Links for TEX35

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX35
genes like me logo Genes that share disorders with TEX35: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX35 Gene

Publications for TEX35 Gene

  1. Identification and characteristics of a novel testis-specific gene, Tsc24, in human and mice. (PMID: 17077512) Tang A. … Cai Z. (Biol. Pharm. Bull. 2006) 2 67
  2. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PMID: 11230166) Wiemann S. … Poustka A. (Genome Res. 2001) 2 67
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  4. A Y2H-seq approach defines the human protein methyltransferase interactome. (PMID: 23455924) Weimann M. … Stelzl U. (Nat. Methods 2013) 67
  5. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 67

Products for TEX35 Gene

Sources for TEX35 Gene

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