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Aliases for TEX33 Gene

Aliases for TEX33 Gene

  • Testis Expressed 33 2 3 5
  • C22orf33 3 4
  • EAN57 3 4
  • Testis-Expressed Sequence 33 Protein 3
  • Chromosome 22 Open Reading Frame 33 2
  • Testis-Expressed Protein 33 3
  • Protein EAN57 3
  • CE81G9.2 3

External Ids for TEX33 Gene

Previous HGNC Symbols for TEX33 Gene

  • C22orf33

Previous GeneCards Identifiers for TEX33 Gene

  • GC22M037388

Summaries for TEX33 Gene

GeneCards Summary for TEX33 Gene

TEX33 (Testis Expressed 33) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX33 Gene

Genomics for TEX33 Gene

Regulatory Elements for TEX33 Gene

Enhancers for TEX33 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22G037030 1.9 FANTOM5 Ensembl ENCODE dbSUPER 12.3 -25.7 -25700 5.4 FOXA2 MLX ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 SLC30A9 TMPRSS6 MPST TEX33 ENSG00000231467 NCF4-AS1 NCF4 IL2RB ENSG00000229971 TST CARD10
GH22G037430 1.4 Ensembl ENCODE dbSUPER 9.4 -424.3 -424321 2.5 SIN3A FEZF1 BRCA1 GLIS2 ZNF143 FOS SP3 JUNB TSHZ1 ZNF518A ELFN2 MFNG IL2RB TEX33 GC22P037457
GH22G036883 1.3 FANTOM5 ENCODE dbSUPER 9.8 +122.9 122851 2.1 BCOR JUN ZMYM3 CEBPG ZNF664 ZNF316 RBAK GATA2 SCRT2 FOS CSF2RB NCF4 TEX33 CYTH4 LOC105373022 NCF4-AS1
GH22G036853 1.2 Ensembl ENCODE dbSUPER 10.4 +154.2 154168 1.1 CTCF CBX3 PKNOX1 ETV1 BMI1 RAD21 YY1 ZNF121 POLR2A ZNF143 PVALB ENSG00000234979 IFT27 TEX33 NCF4
GH22G037204 0.9 dbSUPER 10.1 -197.9 -197930 3.1 TBP FOXA2 PKNOX1 INSM2 ZNF48 YY1 ZEB1 ZNF121 SCRT2 THAP11 C1QTNF6 ENSG00000235237 IL2RB TMPRSS6 ENSG00000231467 TEX33 ENSG00000226233
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TEX33 on UCSC Golden Path with GeneCards custom track

Genomic Location for TEX33 Gene

Chromosome:
22
Start:
36,991,119 bp from pter
End:
37,007,863 bp from pter
Size:
16,745 bases
Orientation:
Minus strand

Genomic View for TEX33 Gene

Genes around TEX33 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX33 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX33 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX33 Gene

Proteins for TEX33 Gene

  • Protein details for TEX33 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O43247-TEX33_HUMAN
    Recommended name:
    Testis-expressed protein 33
    Protein Accession:
    O43247
    Secondary Accessions:
    • B1AH46
    • Q6ICF2
    • Q8IVQ2
    • Q9Y4V8

    Protein attributes for TEX33 Gene

    Size:
    280 amino acids
    Molecular mass:
    30725 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAA72029.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for TEX33 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TEX33 Gene

Post-translational modifications for TEX33 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX33 Gene

No data available for DME Specific Peptides for TEX33 Gene

Domains & Families for TEX33 Gene

Protein Domains for TEX33 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX33 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX33: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEX33 Gene

Function for TEX33 Gene

genes like me logo Genes that share phenotypes with TEX33: view

Animal Model Products

CRISPR Products

miRNA for TEX33 Gene

miRTarBase miRNAs that target TEX33

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TEX33 Gene

Localization for TEX33 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX33 gene
Compartment Confidence
nucleus 3
mitochondrion 1
peroxisome 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TEX33 Gene

Pathways & Interactions for TEX33 Gene

SuperPathways for TEX33 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TEX33 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX33 Gene

Drugs & Compounds for TEX33 Gene

No Compound Related Data Available

Transcripts for TEX33 Gene

mRNA/cDNA for TEX33 Gene

Unigene Clusters for TEX33 Gene

Testis expressed 33:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX33 Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b
SP1:
SP2: -

Relevant External Links for TEX33 Gene

GeneLoc Exon Structure for
TEX33
ECgene alternative splicing isoforms for
TEX33

Expression for TEX33 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TEX33 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TEX33 Gene

This gene is overexpressed in Testis (x52.4).

Protein differential expression in normal tissues from HIPED for TEX33 Gene

This gene is overexpressed in Testis (65.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TEX33 Gene



Protein tissue co-expression partners for TEX33 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TEX33 Gene:

TEX33

SOURCE GeneReport for Unigene cluster for TEX33 Gene:

Hs.124502
genes like me logo Genes that share expression patterns with TEX33: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX33 Gene

Orthologs for TEX33 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEX33 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TEX33 34 35
  • 99.4 (n)
cow
(Bos Taurus)
Mammalia TEX33 34
  • 81.21 (n)
MGC133880 35
  • 72 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TEX33 34 35
  • 80.15 (n)
mouse
(Mus musculus)
Mammalia Tex33 34 16 35
  • 77.11 (n)
rat
(Rattus norvegicus)
Mammalia Tex33 34
  • 75.76 (n)
oppossum
(Monodelphis domestica)
Mammalia TEX33 35
  • 44 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TEX33 35
  • 44 (a)
OneToOne
chicken
(Gallus gallus)
Aves TEX33 35
  • 46 (a)
OneToOne
Species where no ortholog for TEX33 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX33 Gene

ENSEMBL:
Gene Tree for TEX33 (if available)
TreeFam:
Gene Tree for TEX33 (if available)

Paralogs for TEX33 Gene

No data available for Paralogs for TEX33 Gene

Variants for TEX33 Gene

Sequence variations from dbSNP and Humsavar for TEX33 Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs1000008858 -- 36,999,015(+) GGTCA(C/T)ACCCA intron-variant
rs1000145244 -- 37,002,498(+) GAAAT(C/T)AGGAG intron-variant
rs1000468931 -- 37,000,525(+) TGAGT(C/T)CCAGT intron-variant
rs1000636296 -- 37,004,490(+) AGGAT(C/T)GTATC intron-variant
rs1000920715 -- 36,994,713(+) GCAAG(C/T)TCCGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TEX33 Gene

Variant ID Type Subtype PubMed ID
esv34015 CNV loss 18971310
nsv1057409 CNV gain 25217958
nsv459882 CNV gain 19166990
nsv588984 CNV gain 21841781
nsv829203 CNV loss 20364138
nsv834187 CNV loss 17160897
nsv955154 CNV deletion 24416366

Variation tolerance for TEX33 Gene

Residual Variation Intolerance Score: 89% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 6.66; 78.43% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX33 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX33

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX33 Gene

Disorders for TEX33 Gene

Relevant External Links for TEX33

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX33

No disorders were found for TEX33 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX33 Gene

Publications for TEX33 Gene

  1. Identification of testis 14-3-3 binding proteins by tandem affinity purification. (PMID: 22332119) Puri P. … Vijayaraghavan S. (Spermatogenesis 2011) 2 3 64
  2. A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins J.E. … Dunham I. (Genome Biol. 2004) 3 4 64
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 64
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4 64
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for TEX33 Gene

Sources for TEX33 Gene

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