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TEX29 Gene

protein-coding   GIFtS: 36
GCID: GC13P111969

Testis Expressed 29

(Previous name: chromosome 13 open reading frame 16)
(Previous symbol: C13orf16)
  Search for TEX29
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Testis Expressed 291 2     CIRH1A5
C13orf161 2 3     KIAA19885
Chromosome 13 Open Reading Frame 161     NAIC5
bA474D23.12     TEX2925
Testis-Expressed Sequence 29 Protein2     

External Ids:    HGNC: 203701   Entrez Gene: 1217932   Ensembl: ENSG000001534957   OMIM: 6074565   UniProtKB: Q8N6K03   

Export aliases for TEX29 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TEX29 Gene:
TEX29 (testis expressed 29) is a protein-coding gene.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000013.11  NC_018924.2  NT_009952.15  
Regulatory elements:
   Search for regulatory transcription factor binding sites for TEX29
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTEX29 promoter sequence
   Search Chromatin IP Primers for TEX29

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TEX29


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q34   Ensembl cytogenetic band:  13q34   HGNC cytogenetic band: 13q34

TEX29 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TEX29 gene location

GeneLoc information about chromosome 13         GeneLoc Exon Structure

GeneLoc location for GC13P111969:  view genomic region     (about GC identifiers)

Start:
111,968,531 bp from pter      End:
111,996,596 bp from pter
Size:
28,066 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TEX29_HUMAN, Q8N6K0 (See protein sequence)
Recommended Name: Testis-expressed sequence 29 protein  
Size: 151 amino acids; 16649 Da

Explore the universe of human proteins at neXtProt for TEX29: NX_Q8N6K0

Explore proteomics data for TEX29 at MOPED


See TEX29 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_689537.1  
ENSEMBL proteins: 
 ENSP00000431661   ENSP00000283547  

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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ProtoNet protein and cluster: Q8N6K0

1 Blocks protein domain: IPB000519 P-type trefoil domain


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Phenotypes:
     1 GenomeRNAi human phenotype for TEX29:
 Decreased viability with pacli 

Animal Models:
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
TEX29_HUMAN, Q8N6K0: Membrane; Single-pass membrane protein (Potential)

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016021integral component of membrane IEA--

TEX29 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TEX29
Interactions:

    Search GeneGlobe Interaction Network for TEX29

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for TEX29



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for TEX29 gene: 
NM_152324.1  

Unigene Cluster for TEX29:

Testis expressed 29
Hs.210677  [show with all ESTs]
Unigene Representative Sequence: BI830521
2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000497241 ENST00000283547(uc001vsa.3)
miRNA
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Additional mRNA sequence: BC029889.1 

3 DOTS entries:

DT.308693  DT.40121817  DT.95107628 

17 AceView cDNA sequences:

AW028719 AW665078 BX103295 BF509929 BU627480 AA470135 NM_152324 AW070313 
AA586374 BI828648 BC029889 AI004422 AA369807 AI810037 BE327369 AA369808 
AW957098 

GeneLoc Exon Structure

2 Alternative Splicing Database (ASD) splice patterns (SP) for TEX29    About this scheme

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7
SP1:                    -                     
SP2:                                          


ECgene alternative splicing isoforms for TEX29

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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TEX29 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AAGAAGTGGA
TEX29 Expression
About this image

TEX29 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

TEX29 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.210677
    Custom PCR Arrays for TEX29
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In Situ
Assay Products:
 

 
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(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of human and mouse.

Orthologs for TEX29 gene from Selected species (see all 6)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Tex295 RIKEN cDNA 1700018L24 gene   --   8 (5.73 cM) 11840474 


ENSEMBL Gene Tree for TEX29 (if available)
TreeFam Gene Tree for TEX29 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for TEX29 (see all 629)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 13 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs23919311,2
C,F--92569942(-) GCTTCT/CCTCTC 1 -- us2k1 trp37Minor allele frequency- C:0.19NA WA EA 478
rs1113798371,2
F--92569989(+) GGGAAC/TGTGAA 1 -- us2k12Minor allele frequency- T:0.05CSA WA 120
rs1410169941,2
--92570031(+) AGGTCC/TTCAGA 1 -- us2k10--------
rs1442414241,2
--92570144(+) TGGGGA/GCTGGA 1 -- us2k10--------
rs24774651,2
C,F--92570186(+) TCCTCC/TGAAGT 1 -- us2k16Minor allele frequency- T:0.12CSA WA NA EA 364
rs1843217481,2
--92570211(+) ATATCC/TGGCGC 1 -- us2k10--------
rs1452438951,2
--92570214(+) TCCGGC/TGCCTT 1 -- us2k10--------
rs1882007471,2
--92570285(+) GGCACA/GATTCC 1 -- us2k10--------
rs24799661,2
C,F,A--92570296(+) cattcG/Atgagg 1 -- us2k111Minor allele frequency- A:0.45NA CSA WA EA 494
rs1810419261,2
--92570415(+) CTTCCA/CAGCGT 1 -- us2k10--------

HapMap Linkage Disequilibrium report for TEX29 (111968531 - 111996596 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for TEX29: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing TEX29
DNA2.0 Custom Variant and Variant Library Synthesis for TEX29

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 607456   
OMIM disorders: 604901  

TEX29 for disorders           About GeneDecksing


Export disorders for TEX29 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for TEX29 gene integrated from 10 sources:
(articles sorted by number of sources associating them with TEX29)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The DNA sequence and analysis of human chromosome 13. (PubMed id 15057823)1, 2 Dunham A.... Ross M.T. (Nature 2004)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. (PubMed id 19240061)1 Trynka G....Wijmenga C. (Gut 2009)
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 121793 HGNC: 20370 AceView: MGC35169 Ensembl:ENSG00000153495 euGenes: HUgn121793
ECgene: TEX29 H-InvDB: TEX29

(According to HUGE)
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HUGE: KIAA1988

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for TEX29 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for TEX29 gene:
Search GeneIP for patents involving TEX29

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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