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Aliases for TEX28 Gene

Aliases for TEX28 Gene

  • Testis Expressed 28 2 3
  • CXorf2 3 4
  • Chromosome X Open Reading Frame 2 2
  • TEX28 TEX28P1 TEX28P2 4
  • TEX28P1 3
  • TEX28P2 3
  • MRX99 3
  • FTEX 3

External Ids for TEX28 Gene

Previous HGNC Symbols for TEX28 Gene

  • CXorf2

Previous GeneCards Identifiers for TEX28 Gene

  • GC0XM153154
  • GC0XM153498
  • GC0XM142075

Summaries for TEX28 Gene

GeneCards Summary for TEX28 Gene

TEX28 (Testis Expressed 28) is a Protein Coding gene. Diseases associated with TEX28 include mental retardation, x-linked 99 and red color blindness.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX28 Gene

Genomics for TEX28 Gene

Regulatory Elements for TEX28 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TEX28 Gene

Chromosome:
X
Start:
154,271,265 bp from pter
End:
154,295,853 bp from pter
Size:
24,589 bases
Orientation:
Minus strand

Genomic View for TEX28 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TEX28 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX28 Gene

Proteins for TEX28 Gene

  • Protein details for TEX28 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    O15482-TEX28_HUMAN
    Recommended name:
    Testis-specific protein TEX28
    Protein Accession:
    O15482
    Secondary Accessions:
    • B1B1E8
    • D3DWW5

    Protein attributes for TEX28 Gene

    Size:
    410 amino acids
    Molecular mass:
    46131 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX28 Gene

Proteomics data for TEX28 Gene at MOPED

Post-translational modifications for TEX28 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX28 Gene

No data available for DME Specific Peptides for TEX28 Gene

Domains & Families for TEX28 Gene

Protein Domains for TEX28 Gene

Suggested Antigen Peptide Sequences for TEX28 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

O15482

UniProtKB/Swiss-Prot:

TEX28_HUMAN :
  • Belongs to the TEX28 family.
Family:
  • Belongs to the TEX28 family.
genes like me logo Genes that share domains with TEX28: view

No data available for Gene Families for TEX28 Gene

Function for TEX28 Gene

Gene Ontology (GO) - Molecular Function for TEX28 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with TEX28: view
genes like me logo Genes that share phenotypes with TEX28: view

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TEX28

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TEX28 Gene

Localization for TEX28 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEX28 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TEX28 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TEX28: view

No data available for Subcellular locations from COMPARTMENTS for TEX28 Gene

Pathways & Interactions for TEX28 Gene

SuperPathways for TEX28 Gene

No Data Available

Interacting Proteins for TEX28 Gene

Selected Interacting proteins: O15482-TEX28_HUMAN for TEX28 Gene via MINT I2D

Symbol External ID(s) Details
EPS8

Gene Ontology (GO) - Biological Process for TEX28 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with TEX28: view

No data available for Pathways by source and SIGNOR curated interactions for TEX28 Gene

Drugs & Compounds for TEX28 Gene

No Compound Related Data Available

Transcripts for TEX28 Gene

mRNA/cDNA for TEX28 Gene

(7) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TEX28 Gene

Testis expressed 28:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TEX28

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX28 Gene

No ASD Table

Relevant External Links for TEX28 Gene

GeneLoc Exon Structure for
TEX28
ECgene alternative splicing isoforms for
TEX28

Expression for TEX28 Gene

mRNA expression in normal human tissues for TEX28 Gene

mRNA differential expression in normal tissues according to GTEx for TEX28 Gene

This gene is overexpressed in Testis (x53.0).

Protein differential expression in normal tissues from HIPED for TEX28 Gene

This gene is overexpressed in Serum (46.1), Amniocyte (13.6), and Plasma (8.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TEX28 Gene



SOURCE GeneReport for Unigene cluster for TEX28 Gene Hs.672606

mRNA Expression by UniProt/SwissProt for TEX28 Gene

O15482-TEX28_HUMAN
Tissue specificity: Testis specific
genes like me logo Genes that share expression patterns with TEX28: view

Protein tissue co-expression partners for TEX28 Gene

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for TEX28 Gene

Orthologs for TEX28 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TEX28 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TEX28 35
  • 74.77 (n)
  • 62.65 (a)
dog
(Canis familiaris)
Mammalia TEX28 35
  • 76.94 (n)
  • 64.55 (a)
mouse
(Mus musculus)
Mammalia Tex28 35
  • 72.99 (n)
  • 59.61 (a)
Tex28 16
chimpanzee
(Pan troglodytes)
Mammalia TEX28 35
  • 99.51 (n)
  • 99.76 (a)
rat
(Rattus norvegicus)
Mammalia Tex28 35
  • 72.11 (n)
  • 58.91 (a)
Species with no ortholog for TEX28:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX28 Gene

ENSEMBL:
Gene Tree for TEX28 (if available)
TreeFam:
Gene Tree for TEX28 (if available)

Paralogs for TEX28 Gene

(5) SIMAP similar genes for TEX28 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with TEX28: view

No data available for Paralogs for TEX28 Gene

Variants for TEX28 Gene

Sequence variations from dbSNP and Humsavar for TEX28 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs3021120 -- 154,293,615(+) ctgcc(A/G)tgatc intron-variant, upstream-variant-2KB
rs6643837 -- 154,293,039(+) tttga(A/G)accat intron-variant
rs6643838 -- 154,293,093(+) aatta(C/G)ccggg intron-variant
rs6643839 -- 154,293,149(+) cagga(A/G)aattg intron-variant, upstream-variant-2KB
rs6643840 -- 154,293,190(+) gccga(A/G)actgc intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TEX28 Gene

Variant ID Type Subtype PubMed ID
esv33199 CNV Gain+Loss 17666407
esv33784 CNV Gain+Loss 17666407
nsv519042 CNV Gain 19592680
nsv7161 CNV Loss 18451855
esv27518 CNV Gain+Loss 19812545

Relevant External Links for TEX28 Gene

HapMap Linkage Disequilibrium report
TEX28

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TEX28 Gene

Disorders for TEX28 Gene

MalaCards: The human disease database

(5) MalaCards diseases for TEX28 Gene - From: OMIM and DISEASES

Disorder Aliases PubMed IDs
mental retardation, x-linked 99
  • mrx99
red color blindness
  • protanopia
blue cone monochromacy
  • blue cone monochromatism
red-green color blindness
  • deuteranopia
achromatopsia
  • achm
- elite association
Search TEX28 in MalaCards View complete list of genes associated with diseases

Relevant External Links for TEX28

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX28
genes like me logo Genes that share disorders with TEX28: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TEX28 Gene

Publications for TEX28 Gene

  1. An insertion/deletion TEX28 polymorphism and its application to analysis of red/green visual pigment gene arrays. (PMID: 15378397) Ueyama H. … Yamade S. (J. Hum. Genet. 2004) 2 23 67
  2. Evaluation of the X-linked high-grade myopia locus (MYP1) with cone dysfunction and color vision deficiencies. (PMID: 19098318) Metlapally R. … Young T.L. (Invest. Ophthalmol. Vis. Sci. 2009) 23 67
  3. Identification of a gene within the tandem array of red and green color pigment genes. (PMID: 9268643) Hanna M.C. … Kirkness E.F. (Genomics 1997) 2 67
  4. Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions. (PMID: 17567994) Denoeud F. … Reymond A. (Genome Res. 2007) 67
  5. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 67

Products for TEX28 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate TEX28
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TEX28
    • Block miRNA regulation of TEX28 using miScript Target Protectors

    Sources for TEX28 Gene

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