TEX28 Gene
protein-coding GIFtS: 49
GCID: GC0XM153498
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testis expressed 28(Previous name: chromosome X open reading frame 2 )
(Previous symbol: CXorf2)
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Aliases
for TEX28 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Testis Expressed 281 2 | | TEX28P12 | | CXorf21 2 3 | | TEX28P22 | | FTEX1 | | Testis-Specific Protein TEX282 | | Chromosome X Open Reading Frame 21 | | |
Export aliases for TEX28 gene to outside databasesPrevious GC identifers: GC0XM153154 GC0XM142075 |
Summaries
for TEX28 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TEX28 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NT_167198.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TEX28 gene promoter:
HFH-3 AhR AML1a Arnt FOXI1 MZF-1 FOXJ2 (long isoform) Cart-1 Msx-1 FOXJ2
Other transcription factors
Search SABiosciences Chromatin IP Primers for TEX28
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX28 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq28 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xq28TEX28 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM153498: view genomic region
(about GC identifiers)
Start:
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153,498,930 bp from pter |
End:
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153,523,796 bp from pter |
Size:
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24,867 bases |
Orientation:
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minus strand |
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Proteins
for TEX28 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TEX28_HUMAN, O15482 (See
protein sequence)Recommended Name: Testis-specific protein TEX28 Size: 410 amino acids; 46131 Da
Subcellular location: Membrane; Single-pass membrane protein (Potential)
Secondary accessions: B1B1E8 D3DWW5Explore the universe of human proteins at neXtProt for TEX28: NX_O15482
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O15482
TEX28 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001192130.1 NP_001577.1
ENSEMBL proteins: ENSP00000358942 ENSP00000355323 ENSP00000406419
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
NAS | -- |
TEX28 for ontologies About GeneDecksing
TEX28 Antibody Products:
Assay Products for TEX28: |
Protein
Domains /
Families
for TEX28 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TEX28 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O15482ProtoNet protein and cluster: O15482 UniProtKB/Swiss-Prot: TEX28_HUMAN, O15482Similarity: Belongs to the TEX28 family |
Function
for TEX28 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX28 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX28
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TEX28 (NM_001586) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX28 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX28 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX28 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
TEX28 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for TEX28:
|
Pathways & Interactions
for TEX28 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEX28
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for TEX28 (O154822, 3 ENSP000003553234) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
TEX28 for ontologies About GeneDecksing
|
Drugs & Compounds
for TEX28 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TEX28
Search CenterWatch for drugs/clinical trials and news about TEX28
|
Transcripts
for TEX28 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TEX28 gene (2 alternative transcripts): NM_001205201.1 NM_001586.2 Unigene Cluster for TEX28: Testis expressed 28 Hs.672606 [show with all ESTs]Unigene Representative Sequence: BC0261833 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000369926(uc004fkf.3 uc010nut.1) ENST00000361930(uc004fke.3)
ENST00000428625
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX28 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX28
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): TEX28 (NM_001586) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX28 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX28 |
Additional cDNA sequence: BC026183.1 U93720.1 2 DOTS entries: DT.304154 DT.95288742 10 AceView cDNA sequences: BX280786 BI826964 BI825689 BC026183 U93720 BM728212 NM_001586 BI459565 BM681381 AW629285
GeneLoc Exon Structure
|
Expression
for TEX28 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TEX28 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTGATGCTGA
About this image
See TEX28 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TEX28
SOURCE GeneReport for Unigene cluster: Hs.672606
UniProtKB/Swiss-Prot: TEX28_HUMAN, O15482Tissue specificity: Testis specific
SABiosciences Custom PCR Arrays for TEX28
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX28
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TEX28 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX28 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX28 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX28 |
Orthologs
for TEX28 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TEX28 gene from 3/14 species (see all 14) About this table
ENSEMBL Gene Tree for TEX28 (if available)
TreeFam Gene Tree for TEX28 (if available) |
Paralogs
for TEX28 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TEX28 gene
- TEX28P12 TMCC12 TEX28P22 TMCC32 TMCC22
5 SIMAP similar genes for TEX28 using alignment to 2 protein entries: TEX28_HUMAN (see all proteins):TEX28P1 TEX28P2 TMCC3 TMCC1 TMCC2
TEX28 for paralogs About GeneDecksing
|
Genomic Variants
for TEX28 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TEX28 (153498930 - 153523796 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for TEX28
4 CNVs: 97108 83868 37014 74085 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX28 |
|
Disorders
/ Diseases
for TEX28 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TEX28 for disorders About GeneDecksing
OMIM gene information: 300092
OMIM disorders: --
7  diseases for TEX28: About MalaCardsblue cone monochromacy color vision deficiency color blindness achromatopsia
endometritis myopia blindness
3 diseases from the University of Copenhagen DISEASES database for TEX28:Blue cone monochromacy Color blindness Achromatopsia Export disorders for TEX28 gene to outside databases
|
Publications
for TEX28 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TEX28 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TEX28) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of a gene within the tandem array of red and green color pigment genes. (PubMed id 9268643)1, 2, 3 Hanna M.C.... Kirkness E.F. (1997)
- An insertion/deletion TEX28 polymorphism and its appl ication to analysis of red/green visual pigment gene arrays. (PubMed id 15378397)1, 3, 9 Ueyama H....Yamade S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Evaluation of the X-linked high-grade myopia locus (MYP1) with cone dysfunction and color vision deficiencies. (PubMed id 19098318)1, 9 Metlapally R....Young T.L. (2009)
- Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions. (PubMed id 17567994)1 Denoeud F....Reymond A. (2007)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for TEX28 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TEX28 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TEX28 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TEX28 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TEX28 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TEX28 gene:
Search GeneIP for patents involving TEX28
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TEX28 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TEX28 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TEX28 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX28 | | | OriGene Protein Over-expression Lysate for TEX28 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TEX28 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX28 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX28 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TEX28 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TEX28 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX28 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX28 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEX28 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX28 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX28 |
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 |  |  |  | |
| | | | Search Tocris compounds for TEX28 |
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 | | | TEX28 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX28 |
|  |  |  | | | | ThermoFisher Antibody for TEX28 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX28 |
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