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Aliases for TEX22 Gene

Aliases for TEX22 Gene

  • Testis Expressed 22 2 3 5

External Ids for TEX22 Gene

Previous GeneCards Identifiers for TEX22 Gene

  • GC14P105865

Summaries for TEX22 Gene

GeneCards Summary for TEX22 Gene

TEX22 (Testis Expressed 22) is a Protein Coding gene.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX22 Gene

Genomics for TEX22 Gene

Regulatory Elements for TEX22 Gene

Enhancers for TEX22 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G105312 1.2 ENCODE dbSUPER 11.5 -83.1 -83142 5.4 PKNOX1 ARID4B SIN3A ZNF48 ZNF766 GLIS2 ELK1 SP3 GLIS1 KDM1A ENSG00000225200 ENSG00000257270 TEX22 NUDT14 JAG2 MTA1 BRF1 GC14M105304
GH14G105447 1 ENCODE dbSUPER 11.8 +49.7 49650 1.3 CTCF RB1 SAP130 ZIC2 RAD21 ZEB1 GLIS2 PATZ1 ZNF143 SMC3 TEX22 ENSG00000257270 GC14M105345 MTA1
GH14G105451 0.7 ENCODE dbSUPER 11.8 +53.0 52980 0.2 ZNF600 ZBTB8A TEX22 GC14M105345 MTA1
GH14G105859 1.8 FANTOM5 Ensembl ENCODE dbSUPER 1.7 +461.9 461876 8.6 TBP PKNOX1 TBL1XR1 NFIB WRNIP1 SIN3A BMI1 NFXL1 ELK1 CBX5 TEX22 IGHJ6 MIR4537
GH14G105396 1.1 ENCODE 0.7 -0.3 -278 3.1 CREB3L1 ARID4B SIN3A DMAP1 ZBTB7B ZNF143 ZNF207 SP3 SP5 ZHX2 TEX22 GC14P105395
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TEX22 on UCSC Golden Path with GeneCards custom track

Promoters for TEX22 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000073815 17 1201 CREB3L1 ARID4B SIN3A DMAP1 ZBTB7B SLC30A9 ZNF143 ZNF207 SP3 SP5

Genomic Location for TEX22 Gene

Chromosome:
14
Start:
105,398,579 bp from pter
End:
105,450,106 bp from pter
Size:
51,528 bases
Orientation:
Plus strand

Genomic View for TEX22 Gene

Genes around TEX22 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX22 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX22 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX22 Gene

Proteins for TEX22 Gene

  • Protein details for TEX22 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    C9J3V5-TEX22_HUMAN
    Recommended name:
    Testis-expressed protein 22
    Protein Accession:
    C9J3V5

    Protein attributes for TEX22 Gene

    Size:
    150 amino acids
    Molecular mass:
    16880 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX22 Gene

Post-translational modifications for TEX22 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX22 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX22 Gene

Domains & Families for TEX22 Gene

Protein Domains for TEX22 Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TEX22 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX22: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEX22 Gene

Function for TEX22 Gene

Phenotypes for TEX22 Gene

GenomeRNAi human phenotypes for TEX22:
genes like me logo Genes that share phenotypes with TEX22: view

Animal Model Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TEX22 Gene

Localization for TEX22 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEX22 Gene

Cytoplasm. Cytoplasmic vesicle, secretory vesicle, acrosome.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX22 gene
Compartment Confidence
nucleus 3
cytosol 1

Gene Ontology (GO) - Cellular Components for TEX22 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001669 acrosomal vesicle IEA --
GO:0005737 cytoplasm IEA --
GO:0031410 cytoplasmic vesicle IEA --
genes like me logo Genes that share ontologies with TEX22: view

Pathways & Interactions for TEX22 Gene

SuperPathways for TEX22 Gene

No Data Available

Interacting Proteins for TEX22 Gene

Gene Ontology (GO) - Biological Process for TEX22 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEX22 Gene

Transcripts for TEX22 Gene

mRNA/cDNA for TEX22 Gene

(2) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TEX22 Gene

Testis expressed 22:
Representative Sequences:

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX22 Gene

No ASD Table

Relevant External Links for TEX22 Gene

GeneLoc Exon Structure for
TEX22
ECgene alternative splicing isoforms for
TEX22

Expression for TEX22 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TEX22 Gene

mRNA differential expression in normal tissues according to GTEx for TEX22 Gene

This gene is overexpressed in Testis (x15.1).

NURSA nuclear receptor signaling pathways regulating expression of TEX22 Gene:

TEX22

SOURCE GeneReport for Unigene cluster for TEX22 Gene:

Hs.729499
genes like me logo Genes that share expression patterns with TEX22: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX22 Gene

Orthologs for TEX22 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TEX22 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TEX22 35
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC100855864 34
  • 79.68 (n)
TEX22 35
  • 67 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TEX22 34
  • 76.51 (n)
rat
(Rattus norvegicus)
Mammalia Tex22 34
  • 69.63 (n)
mouse
(Mus musculus)
Mammalia Tex22 34 16 35
  • 68.93 (n)
Species where no ortholog for TEX22 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX22 Gene

ENSEMBL:
Gene Tree for TEX22 (if available)
TreeFam:
Gene Tree for TEX22 (if available)

Paralogs for TEX22 Gene

Pseudogenes.org Pseudogenes for TEX22 Gene

genes like me logo Genes that share paralogs with TEX22: view

No data available for Paralogs for TEX22 Gene

Variants for TEX22 Gene

Sequence variations from dbSNP and Humsavar for TEX22 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs1000879303 -- 105,396,807(+) CTGCT(C/T)TTCCT upstream-variant-2KB, utr-variant-3-prime
rs1000908816 -- 105,396,561(+) AGTGG(C/T)ATGAT upstream-variant-2KB, utr-variant-3-prime
rs1001029210 -- 105,405,208(+) TCACT(G/T)GTGTC intron-variant
rs1001290981 -- 105,401,560(+) GGGAA(C/T)ATCAC intron-variant
rs1001727493 -- 105,402,145(+) TCCGC(A/C)ACCAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TEX22 Gene

Variant ID Type Subtype PubMed ID
dgv3986n54 CNV loss 21841781
esv2760014 CNV loss 17122850
nsv1054190 CNV gain 25217958
nsv1160204 CNV duplication 26073780
nsv470679 CNV loss 18288195
nsv517055 CNV gain+loss 19592680
nsv566189 CNV gain 21841781
nsv566204 CNV gain 21841781
nsv566205 CNV loss 21841781
nsv817647 CNV gain 17921354
nsv832889 CNV loss 17160897
nsv832890 CNV loss 17160897
nsv952282 CNV deletion 24416366

Variation tolerance for TEX22 Gene

Gene Damage Index Score: 2.45; 43.10% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX22 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEX22

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX22 Gene

Disorders for TEX22 Gene

Relevant External Links for TEX22

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX22

No disorders were found for TEX22 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX22 Gene

Publications for TEX22 Gene

  1. The DNA sequence and analysis of human chromosome 14. (PMID: 12508121) Heilig R. … Weissenbach J. (Nature 2003) 4 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for TEX22 Gene

Sources for TEX22 Gene

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