Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TEX2 Gene

Aliases for TEX2 Gene

  • Testis Expressed 2 2 3
  • Transmembrane Protein 96 2 3 4
  • Testis Expressed Sequence 2 2 3
  • TMEM96 3 4
  • Testis-Expressed Sequence 2 Protein 3
  • KIAA1738 4
  • HT008 3
  • TEX28 6

External Ids for TEX2 Gene

Summaries for TEX2 Gene

GeneCards Summary for TEX2 Gene

TEX2 (Testis Expressed 2) is a Protein Coding gene. GO annotations related to this gene include phospholipid binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX2 Gene

Genomics for TEX2 Gene

Genomic Location for TEX2 Gene

Start:
64,147,227 bp from pter
End:
64,263,323 bp from pter
Size:
116,097 bases
Orientation:
Minus strand

Genomic View for TEX2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TEX2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX2 Gene

Regulatory Elements for TEX2 Gene

Proteins for TEX2 Gene

  • Protein details for TEX2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IWB9-TEX2_HUMAN
    Recommended name:
    Testis-expressed sequence 2 protein
    Protein Accession:
    Q8IWB9
    Secondary Accessions:
    • Q6AHZ5
    • Q8N3L0
    • Q9C0C5

    Protein attributes for TEX2 Gene

    Size:
    1127 amino acids
    Molecular mass:
    125303 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TEX2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TEX2 Gene

Proteomics data for TEX2 Gene at MOPED

Post-translational modifications for TEX2 Gene

  • Modification sites at PhosphoSitePlus
  • Glycosylation at Asn330

No data available for DME Specific Peptides for TEX2 Gene

Domains for TEX2 Gene

Protein Domains for TEX2 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX2: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEX2 Gene

Function for TEX2 Gene

Gene Ontology (GO) - Molecular Function for TEX2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with TEX2: view

Phenotypes for TEX2 Gene

genes like me logo Genes that share phenotypes with TEX2: view

miRNA for TEX2 Gene

miRTarBase miRNAs that target TEX2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TEX2 Gene

Localization for TEX2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEX2 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TEX2 Gene COMPARTMENTS Subcellular localization image for TEX2 gene
Compartment Confidence
plasma membrane 3
nucleus 2
cytosol 1

Gene Ontology (GO) - Cellular Components for TEX2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane NAS 16449791
genes like me logo Genes that share ontologies with TEX2: view

Pathways for TEX2 Gene

SuperPathways for TEX2 Gene

No Data Available

Interacting Proteins for TEX2 Gene

Gene Ontology (GO) - Biological Process for TEX2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006665 sphingolipid metabolic process NAS 16449791
GO:0007165 signal transduction NAS 16449791
genes like me logo Genes that share ontologies with TEX2: view

No data available for Pathways by source for TEX2 Gene

Transcripts for TEX2 Gene

Unigene Clusters for TEX2 Gene

Testis expressed 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TEX2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b
SP1: - -
SP2: -
SP3:
SP4:
SP5: - -
SP6: -
SP7: - - - -
SP8: - - -
SP9:

Relevant External Links for TEX2 Gene

GeneLoc Exon Structure for
TEX2
ECgene alternative splicing isoforms for
TEX2

Expression for TEX2 Gene

mRNA expression in normal human tissues for TEX2 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TEX2 Gene

SOURCE GeneReport for Unigene cluster for TEX2 Gene Hs.175414

genes like me logo Genes that share expressions with TEX2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TEX2 Gene

Orthologs for TEX2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TEX2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TEX2 35
  • 99.53 (n)
  • 99.65 (a)
TEX2 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TEX2 35
  • 89.12 (n)
  • 90.12 (a)
TEX2 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TEX2 35
  • 91.47 (n)
  • 92.96 (a)
TEX2 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tex2 35
  • 87.28 (n)
  • 90.39 (a)
Tex2 16
Tex2 36
  • 90 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TEX2 36
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 73 (a)
OneToMany
-- 36
  • 81 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Tex2 35
  • 87.62 (n)
  • 89.7 (a)
chicken
(Gallus gallus)
Aves TEX2 35
  • 74.11 (n)
  • 75.5 (a)
TEX2 36
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TEX2 36
  • 74 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.24580 35
tropical clawed frog
(Silurana tropicalis)
Amphibia tex2.2 35
  • 67.47 (n)
  • 69.13 (a)
zebrafish
(Danio rerio)
Actinopterygii tex2 35
  • 63.24 (n)
  • 64.13 (a)
tex2 36
  • 59 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG43783 36
  • 21 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F55C12.5 36
  • 26 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes -- 38
sea squirt
(Ciona savignyi)
Ascidiacea CSA.7607 36
  • 40 (a)
OneToOne
Species with no ortholog for TEX2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TEX2 Gene

ENSEMBL:
Gene Tree for TEX2 (if available)
TreeFam:
Gene Tree for TEX2 (if available)

Paralogs for TEX2 Gene

Selected SIMAP similar genes for TEX2 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with TEX2: view

No data available for Paralogs for TEX2 Gene

Variants for TEX2 Gene

Sequence variations from dbSNP and Humsavar for TEX2 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs756277 -- 64,265,203(-) CATCC(A/G)TCAGA upstream-variant-2KB
rs880406 -- 64,173,595(+) TGTTC(A/G)AAGGC intron-variant
rs903284 -- 64,160,140(+) GCAGT(A/C)ATTTT intron-variant
rs903285 -- 64,174,435(+) TGCCC(A/G)TCTAT intron-variant
rs903286 -- 64,174,638(+) CCCTC(C/T)GGAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TEX2 Gene

Variant ID Type Subtype PubMed ID
nsv483108 CNV Loss 15286789
nsv2117 CNV Loss 18451855
nsv524852 CNV Gain 19592680
esv2716103 CNV Deletion 23290073

Relevant External Links for TEX2 Gene

HapMap Linkage Disequilibrium report
TEX2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX2 Gene

Disorders for TEX2 Gene

No disorders were found for TEX2 Gene.

No data available for UniProtKB/Swiss-Prot for TEX2 Gene

Publications for TEX2 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11214970) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Diverse membrane-associated proteins contain a novel SMP domain. (PMID: 16449791) Lee I. … Hong W. (FASEB J. 2006) 3
  4. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  5. The full-ORF clone resource of the German cDNA consortium. (PMID: 17974005) Bechtel S. … Schupp I. (BMC Genomics 2007) 4

Products for TEX2 Gene

Sources for TEX2 Gene

Back to Top

Content