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Aliases for TEX2 Gene

Aliases for TEX2 Gene

  • Testis Expressed 2 2 3 5
  • Transmembrane Protein 96 2 3 4
  • Testis Expressed Sequence 2 2 3
  • TMEM96 3 4
  • KIAA1738 4
  • HT008 3

External Ids for TEX2 Gene

Previous GeneCards Identifiers for TEX2 Gene

  • GC17M059579
  • GC17M062224
  • GC17M057594

Summaries for TEX2 Gene

GeneCards Summary for TEX2 Gene

TEX2 (Testis Expressed 2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX2 Gene

Genomics for TEX2 Gene

Regulatory Elements for TEX2 Gene

Enhancers for TEX2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TEX2 on UCSC Golden Path with GeneCards custom track

Promoters for TEX2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TEX2 on UCSC Golden Path with GeneCards custom track

Genomic Location for TEX2 Gene

Chromosome:
17
Start:
64,147,227 bp from pter
End:
64,263,323 bp from pter
Size:
116,097 bases
Orientation:
Minus strand

Genomic View for TEX2 Gene

Genes around TEX2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX2 Gene

Proteins for TEX2 Gene

  • Protein details for TEX2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8IWB9-TEX2_HUMAN
    Recommended name:
    Testis-expressed sequence 2 protein
    Protein Accession:
    Q8IWB9
    Secondary Accessions:
    • Q6AHZ5
    • Q8N3L0
    • Q9C0C5

    Protein attributes for TEX2 Gene

    Size:
    1127 amino acids
    Molecular mass:
    125303 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TEX2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TEX2 Gene

Proteomics data for TEX2 Gene at MOPED

Post-translational modifications for TEX2 Gene

  • Glycosylation at Asn 330
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for TEX2 Gene

Domains & Families for TEX2 Gene

Protein Domains for TEX2 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX2: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEX2 Gene

Function for TEX2 Gene

genes like me logo Genes that share phenotypes with TEX2: view

Animal Model Products

miRNA for TEX2 Gene

miRTarBase miRNAs that target TEX2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TEX2 Gene

Localization for TEX2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEX2 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TEX2 Gene COMPARTMENTS Subcellular localization image for TEX2 gene
Compartment Confidence
nucleus 3
plasma membrane 3
cytosol 1

No data available for Gene Ontology (GO) - Cellular Components for TEX2 Gene

Pathways & Interactions for TEX2 Gene

SuperPathways for TEX2 Gene

No Data Available

Interacting Proteins for TEX2 Gene

Gene Ontology (GO) - Biological Process for TEX2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007165 signal transduction NAS 16449791
genes like me logo Genes that share ontologies with TEX2: view

No data available for Pathways by source and SIGNOR curated interactions for TEX2 Gene

Drugs & Compounds for TEX2 Gene

No Compound Related Data Available

Transcripts for TEX2 Gene

Unigene Clusters for TEX2 Gene

Testis expressed 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TEX2 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15 ^ 16 ^ 17 ^ 18a · 18b
SP1: - -
SP2: -
SP3:
SP4:
SP5: - -
SP6: -
SP7: - - - -
SP8: - - -
SP9:

Relevant External Links for TEX2 Gene

GeneLoc Exon Structure for
TEX2
ECgene alternative splicing isoforms for
TEX2

Expression for TEX2 Gene

mRNA expression in normal human tissues for TEX2 Gene

Protein differential expression in normal tissues from HIPED for TEX2 Gene

This gene is overexpressed in Pancreas (19.0), Plasma (12.5), Breast (8.9), and Lung (8.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for TEX2 Gene



SOURCE GeneReport for Unigene cluster for TEX2 Gene Hs.175414

genes like me logo Genes that share expression patterns with TEX2: view

Protein tissue co-expression partners for TEX2 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TEX2 Gene

Orthologs for TEX2 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for TEX2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TEX2 35
  • 89.12 (n)
  • 90.12 (a)
TEX2 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TEX2 35
  • 91.47 (n)
  • 92.96 (a)
TEX2 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tex2 35
  • 87.28 (n)
  • 90.39 (a)
Tex2 16
Tex2 36
  • 90 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TEX2 35
  • 99.53 (n)
  • 99.65 (a)
TEX2 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tex2 35
  • 87.62 (n)
  • 89.7 (a)
oppossum
(Monodelphis domestica)
Mammalia TEX2 36
  • 82 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 73 (a)
OneToMany
-- 36
  • 81 (a)
OneToMany
chicken
(Gallus gallus)
Aves TEX2 35
  • 74.11 (n)
  • 75.5 (a)
TEX2 36
  • 75 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TEX2 36
  • 74 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tex2.2 35
  • 67.47 (n)
  • 69.13 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.24580 35
zebrafish
(Danio rerio)
Actinopterygii tex2 35
  • 63.24 (n)
  • 64.13 (a)
tex2 36
  • 59 (a)
OneToOne
fruit fly
(Drosophila melanogaster)
Insecta CG43783 36
  • 21 (a)
OneToOne
worm
(Caenorhabditis elegans)
Secernentea F55C12.5 36
  • 26 (a)
OneToOne
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes NVJ2 38
sea squirt
(Ciona savignyi)
Ascidiacea CSA.7607 36
  • 40 (a)
OneToOne
Species with no ortholog for TEX2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TEX2 Gene

ENSEMBL:
Gene Tree for TEX2 (if available)
TreeFam:
Gene Tree for TEX2 (if available)

Paralogs for TEX2 Gene

(1) SIMAP similar genes for TEX2 Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with TEX2: view

No data available for Paralogs for TEX2 Gene

Variants for TEX2 Gene

Sequence variations from dbSNP and Humsavar for TEX2 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs28605685 - 64,213,745(+) AACTG(A/C/G)TTTTC reference, missense
rs923912 -- 64,165,318(+) GCCTT(A/G)TCTAC intron-variant
rs935315 -- 64,203,217(-) AGTGC(C/T)TGAAT intron-variant
rs940742 -- 64,204,216(-) TATAA(A/C)TTATA intron-variant
rs940744 -- 64,215,762(-) GATTG(C/T)GGTAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TEX2 Gene

Variant ID Type Subtype PubMed ID
nsv483108 CNV Loss 15286789
nsv2117 CNV Loss 18451855
nsv524852 CNV Gain 19592680
esv2716103 CNV Deletion 23290073

Variation tolerance for TEX2 Gene

Residual Variation Intolerance Score: 19.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.66; 65.83% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TEX2 Gene

Disorders for TEX2 Gene

Relevant External Links for TEX2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX2

No disorders were found for TEX2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX2 Gene

Publications for TEX2 Gene

  1. Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PMID: 11214970) Nagase T. … Ohara O. (DNA Res. 2000) 2 3 4 67
  2. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3
  3. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3
  4. Diverse membrane-associated proteins contain a novel SMP domain. (PMID: 16449791) Lee I. … Hong W. (FASEB J. 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for TEX2 Gene

Sources for TEX2 Gene

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