Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TEX19 Gene

Aliases for TEX19 Gene

  • Testis Expressed 19 2 3

External Ids for TEX19 Gene

Previous GeneCards Identifiers for TEX19 Gene

  • GC17P077911
  • GC17P080317
  • GC17P075715

Summaries for TEX19 Gene

GeneCards Summary for TEX19 Gene

TEX19 (Testis Expressed 19) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TEX19 Gene

  • Required during spermatogenesis and placenta development, probably by participating to the repression of retrotransposable elements and prevent their mobilization.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX19 Gene

Genomics for TEX19 Gene

Regulatory Elements for TEX19 Gene

Genomic Location for TEX19 Gene

Chromosome:
17
Start:
82,359,247 bp from pter
End:
82,363,776 bp from pter
Size:
4,530 bases
Orientation:
Plus strand

Genomic View for TEX19 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TEX19 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX19 Gene

Proteins for TEX19 Gene

  • Protein details for TEX19 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NA77-TEX19_HUMAN
    Recommended name:
    Testis-expressed sequence 19 protein
    Protein Accession:
    Q8NA77

    Protein attributes for TEX19 Gene

    Size:
    164 amino acids
    Molecular mass:
    18469 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX19 Gene

Proteomics data for TEX19 Gene at MOPED

Post-translational modifications for TEX19 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX19 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX19 Gene

Domains & Families for TEX19 Gene

Protein Domains for TEX19 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX19 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX19: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEX19 Gene

Function for TEX19 Gene

Molecular function for TEX19 Gene

UniProtKB/Swiss-Prot Function:
Required during spermatogenesis and placenta development, probably by participating to the repression of retrotransposable elements and prevent their mobilization.
UniProtKB/Swiss-Prot Induction:
Down-regulated by gonadotropin suppression sufficient to cause marked suppression of spermatogenesis and additionally progestogen treatment.
genes like me logo Genes that share phenotypes with TEX19: view

Animal Model Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TEX19 Gene

Localization for TEX19 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEX19 Gene

Cytoplasm. Note=Cytoplasmic localization is distinct from the meiotic nuage, also named P granule, a germ-cell-specific organelle required to repress transposon activity during meiosis. {ECO:0000250}.

Gene Ontology (GO) - Cellular Components for TEX19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with TEX19: view

No data available for Subcellular locations from COMPARTMENTS for TEX19 Gene

Pathways & Interactions for TEX19 Gene

SuperPathways for TEX19 Gene

No Data Available

Interacting Proteins for TEX19 Gene

Gene Ontology (GO) - Biological Process for TEX19 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007283 spermatogenesis IEA --
GO:0030154 cell differentiation IEA --
GO:0051321 meiotic cell cycle IEA --
genes like me logo Genes that share ontologies with TEX19: view

No data available for Pathways by source and SIGNOR curated interactions for TEX19 Gene

Drugs & Compounds for TEX19 Gene

No Compound Related Data Available

Transcripts for TEX19 Gene

mRNA/cDNA for TEX19 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(31) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TEX19 Gene

Testis expressed 19:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TEX19 Gene

No ASD Table

Relevant External Links for TEX19 Gene

GeneLoc Exon Structure for
TEX19
ECgene alternative splicing isoforms for
TEX19

Expression for TEX19 Gene

mRNA expression in normal human tissues for TEX19 Gene

mRNA differential expression in normal tissues according to GTEx for TEX19 Gene

This gene is overexpressed in Testis (x50.3).

SOURCE GeneReport for Unigene cluster for TEX19 Gene Hs.231897

mRNA Expression by UniProt/SwissProt for TEX19 Gene

Q8NA77-TEX19_HUMAN
Tissue specificity: Expressed in testis. Expressed in undifferentiated embryonic stem cells.
genes like me logo Genes that share expression patterns with TEX19: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for TEX19 Gene

Orthologs for TEX19 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TEX19 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC100299732 35
  • 79.14 (n)
  • 70.55 (a)
-- 36
  • 32 (a)
OneToMany
-- 36
  • 34 (a)
OneToMany
-- 36
  • 33 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Tex19.2 35
  • 70.14 (n)
  • 59.03 (a)
Tex19.1 36
  • 24 (a)
OneToMany
Tex19.2 36
  • 27 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia TEX19 35
  • 99.59 (n)
  • 100 (a)
TEX19 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tex19.2 35
  • 70.3 (n)
  • 58.33 (a)
Species with no ortholog for TEX19:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX19 Gene

ENSEMBL:
Gene Tree for TEX19 (if available)
TreeFam:
Gene Tree for TEX19 (if available)

Paralogs for TEX19 Gene

No data available for Paralogs for TEX19 Gene

Variants for TEX19 Gene

Sequence variations from dbSNP and Humsavar for TEX19 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs7212418 -- 82,358,420(+) gctct(A/G)tgaca upstream-variant-2KB
rs7502620 -- 82,362,685(+) AGCCC(A/G)TGGTG utr-variant-3-prime
rs11077988 -- 82,359,291(+) GTGAG(A/G)TCTCC intron-variant
rs11557867 -- 82,362,201(+) TACCT(C/G)TACGC reference, synonymous-codon
rs11651514 -- 82,362,127(+) CACCC(A/C/G/T)GGCAG utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for TEX19 Gene

Variant ID Type Subtype PubMed ID
nsv909052 CNV Loss 21882294
nsv428351 CNV Gain 18775914
dgv3332n71 CNV Loss 21882294
nsv909134 CNV Loss 21882294
esv21913 CNV Gain+Loss 19812545
dgv3341n71 CNV Loss 21882294
dgv3353n71 CNV Loss 21882294
dgv3354n71 CNV Loss 21882294
nsv833572 CNV Loss 17160897
dgv3355n71 CNV Loss 21882294
nsv909208 CNV Loss 21882294
nsv469561 CNV Complex 16826518
dgv3356n71 CNV Loss 21882294
nsv909217 CNV Loss 21882294
nsv833573 CNV Loss 17160897
dgv3357n71 CNV Loss 21882294
nsv909220 CNV Loss 21882294
dgv3358n71 CNV Loss 21882294
nsv909223 CNV Loss 21882294
dgv3359n71 CNV Loss 21882294
nsv821135 CNV Deletion 20802225
esv2716489 CNV Deletion 23290073
esv2716490 CNV Deletion 23290073
esv2162612 CNV Deletion 18987734
esv1367803 CNV Insertion 17803354
nsv112382 CNV Loss 16902084

Variation tolerance for TEX19 Gene

Residual Variation Intolerance Score: 74.46% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.14; 38.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX19 Gene

HapMap Linkage Disequilibrium report
TEX19

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX19 Gene

Disorders for TEX19 Gene

Relevant External Links for TEX19

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX19
genes like me logo Genes that share disorders with TEX19: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX19 Gene

Publications for TEX19 Gene

  1. The BTB and CNC homology 1 (BACH1) target genes are involved in the oxidative stress response and in control of the cell cycle. (PMID: 21555518) Warnatz H.J. … Yaspo M.L. (J. Biol. Chem. 2011) 67
  2. Tex19, a mammalian-specific protein with a restricted expression in pluripotent stem cells and germ line. (PMID: 18096721) Kuntz S. … Viville S. (Stem Cells 2008) 67
  3. Molecular profiling of the human testis reveals stringent pathway- specific regulation of RNA expression following gonadotropin suppression and progestogen treatment. (PMID: 18160741) Bayne R.A. … Anderson R.A. (J. Androl. 2008) 67
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for TEX19 Gene

Sources for TEX19 Gene

Back to Top

Content