TEX15 Gene
protein-coding GIFtS: 44
GCID: GC08M030689
|
|
testis expressed 15(Previous name: testis expressed sequence 15 )
| |
Aliases
for TEX15 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Testis Expressed 151 2 | | CT421 2 3 | | Cancer/Testis Antigen 422 3 | | Testis Expressed Sequence 151 | | Testis-Expressed Sequence 15 Protein2 |
Export aliases for TEX15 gene to outside databasesPrevious GC identifers: GC08M030510 GC08M031141 GC08M030545 GC08M030746 GC08M030808 GC08M029235 |
Summaries
for TEX15 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TEX15 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000008.10 NC_018919.1 NT_167187.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TEX15 gene promoter:
AML1a IRF-2 POU2F1 POU2F1b POU2F1a IRF-7A POU2F1c NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for TEX15
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX15 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 8p12 Ensembl cytogenetic band: 8p12 HGNC cytogenetic band: 8p22TEX15 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 8 GeneLoc Exon Structure GeneLoc location for GC08M030689: view genomic region
(about GC identifiers)
Start:
|
30,689,060 bp from pter |
End:
|
30,748,122 bp from pter |
Size:
|
59,063 bases |
Orientation:
|
minus strand |
|
Proteins
for TEX15 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TEX15_HUMAN, Q9BXT5 (See
protein sequence)Recommended Name: Testis-expressed sequence 15 protein Size: 2789 amino acids; 315336 DaExplore the universe of human proteins at neXtProt for TEX15: NX_Q9BXT5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BXT5
TEX15 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_112561.2
ENSEMBL proteins: ENSP00000256246
Human Recombinant Protein Products:
TEX15 Antibody Products:
Assay Products for TEX15: |
Protein
Domains /
Families
for TEX15 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TEX15 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9BXT5ProtoNet protein and cluster: Q9BXT5 |
Function
for TEX15 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX15 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX15
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TEX15 (NM_031271) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX15 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TEX15 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX15 |
1 GenomeRNAi human phenotype for TEX15:
Animal Models:
4 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Tex15):
TEX15 for phenotypes About GeneDecksing
|
Pathways & Interactions
for TEX15 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEX15
STRING Interaction
Network Preview (showing 5 interactants - click image to see 12)
5/12 Interacting proteins for TEX15 (ENSP000002562464) via UniProtKB, MINT, STRING, and/or I2D (see all 12)About this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
TEX15 for ontologies About GeneDecksing
|
Drugs & Compounds
for TEX15 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TEX15
Search CenterWatch for drugs/clinical trials and news about TEX15
|
Transcripts
for TEX15 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TEX15 gene: NM_031271.3 Unigene Clusters for TEX15: Testis expressed 15 Hs.458316 [show with all ESTs], Hs.571446 [show with all ESTs]Unigene Representative Sequences: NM_031271, BC1418413 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000256246(uc003xil.3) ENST00000523186(uc011lbc.2) ENST00000518257
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX15 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX15
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TEX15 (NM_031271) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX15 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TEX15 |
Additional cDNA sequence: BC141841.1 4 DOTS entries: DT.75167697 DT.121480171 DT.121480169 DT.121480170 16 AceView cDNA sequences: AI798060 AL133653 BX503105 NM_031271 BX280519 AF285605 AL705527 BQ432876 AL703692 BX492383 AL704625 AL705557 AA432326 BG493629 AW303407 BQ438658
GeneLoc Exon Structure
|
Expression
for TEX15 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TEX15 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATTCAGACAT
About this image
See TEX15 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TEX15
SOURCE GeneReport for Unigene clusters: Hs.458316 Hs.571446
UniProtKB/Swiss-Prot: TEX15_HUMAN, Q9BXT5Tissue specificity: Testis-specific. Also expressed in several cancers
SABiosciences Custom PCR Arrays for TEX15
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX15
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TEX15 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX15 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX15 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX15 |
Orthologs
for TEX15 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TEX15 gene from 2/8 species (see all 8) About this table
ENSEMBL Gene Tree for TEX15 (if available)
TreeFam Gene Tree for TEX15 (if available) |
Paralogs
for TEX15 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TEX15 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 8 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TEX15 (30689060 - 30748122 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TEX15: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX15 |
|
Disorders
/ Diseases
for TEX15 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TEX15 for disorders About GeneDecksing
OMIM gene information: 605795
OMIM disorders: --
1  disease for TEX15: About MalaCardsazoospermia
1 disease from the University of Copenhagen DISEASES database for TEX15:Azoospermia Human Genome Epidemiology (HuGE) Navigator: TEX15 (1 document)
Export disorders for TEX15 gene to outside databases
|
Publications
for TEX15 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TEX15 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TEX15) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- An abundance of X-linked genes expressed in spermatogonia. (PubMed id 11279525)1, 2, 3 Wang P.J.... Page D.C. (2001)
- Five new human cancer-germline genes identified among 12 genes expressed in spermatogonia. (PubMed id 12704671)1, 2 Loriot A.... De Smet C. (2003)
- Evaluation of 172 candidate polymorphisms for associa tion with oligozoospermia or azoospermia in a large cohort of men of European d escent. (PubMed id 20378615)1 Aston K.I....Carrell D.T. (2010)
- DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for TEX15 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TEX15 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TEX15 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TEX15 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TEX15 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TEX15 gene:
Search GeneIP for patents involving TEX15
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TEX15 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TEX15 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TEX15 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX15 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TEX15 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX15 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX15 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TEX15 | | OriGene Custom Protein Services for TEX15 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TEX15 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX15 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX15 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEX15 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX15 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX15 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for TEX15 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | TEX15 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX15 |
|  |  |  | | | | Search ThermoFisher Antibodies for TEX15 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TEX15 |
|
|
|
|
