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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TEX13A Gene

protein-coding   GIFtS: 40
GCID: GC0XM104463

testis expressed 13A

(Previous name: testis expressed sequence 13A )
  Search for TEX13A
in
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TEX13A    

Aliases
for TEX13A gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Testis Expressed 13A1 2
Testis Expressed Sequence 13A1 2
Testis-Expressed Sequence 13A Protein2

External Ids:    HGNC: 117351   Entrez Gene: 561572   Ensembl: ENSG000001331497   OMIM: 3003125   UniProtKB: Q9BXU33   

Export aliases for TEX13A gene to outside databases

Previous GC identifers: GC0XM099775 GC0XM101382 GC0XM102496 GC0XM103235 GC0XM104269 GC0XM094089


Summaries
for TEX13A gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TEX13A:
This gene is similar to a mouse gene that is expressed in the testis. (provided by RefSeq, Jul 2008)




Genomic Views
for TEX13A gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_011651.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TEX13A gene promoter:
         Sox5   LCR-F1   GATA-1   HNF-1A   MEF-2A   CP2   HNF-1   Cart-1   aMEF-2   Msx-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TEX13A promoter sequence
   Search SABiosciences Chromatin IP Primers for TEX13A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX13A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq22.3   Ensembl cytogenetic band:  Xq22.3   HGNC cytogenetic band: Xq28

TEX13A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TEX13A gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM104463:  view genomic region     (about GC identifiers)

Start:
 104,463,611 bp from pter      End:
 104,465,358 bp from pter
Size:
 1,748 bases      Orientation:
 minus strand

Proteins
for TEX13A gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TX13A_HUMAN, Q9BXU3 (See protein sequence)
Recommended Name: Testis-expressed sequence 13A protein  
Size: 409 amino acids; 45583 Da
Sequence caution: Sequence=CAI41996.1; Type=Erroneous gene model prediction;
Secondary accessions: B1B1G8 Q32NB6

Explore the universe of human proteins at neXtProt for TEX13A: NX_Q9BXU3

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BXU3

    • TEX13A Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_112564.1  
    ENSEMBL proteins: 
     ENSP00000361659   ENSP00000361656   ENSP00000399753  

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    Uscn Proteins for TEX13A

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IEA--


    TEX13A for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for TEX13A gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TEX13A for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR001876 Znf_RanBP2

    Graphical View of Domain Structure for InterPro Entry Q9BXU3

    ProtoNet protein and cluster: Q9BXU3

    1 Blocks protein family: IPB001876 Zn-finger

    UniProtKB/Swiss-Prot: TX13A_HUMAN, Q9BXU3
    Similarity: Contains 1 RanBP2-type zinc finger


    Function
    for TEX13A gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TEX13A
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    Inhib. RNA
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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008270zinc ion binding IEA--


    TEX13A for ontologies           About GeneDecksing



    Pathways & Interactions
    for TEX13A gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEX13A

    Drugs & Compounds
    for TEX13A gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TEX13A
    Search CenterWatch for drugs/clinical trials and news about TEX13A / TX13A 

    Transcripts
    for TEX13A gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TEX13A gene: 
    NM_031274.3  

    Unigene Cluster for TEX13A:

    Testis expressed 13A
    Hs.567543  [show with all ESTs]
    Unigene Representative Sequence: BC042547
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000372578(uc004ema.3 uc004emb.3) ENST00000372575 ENST00000413579


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    Clone
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    Primer
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    Additional cDNA sequence: 

    AF285597.1 BC042547.1 BC108734.1 

    3 DOTS entries:

    DT.95142259  DT.95094757  DT.404650 

    10 AceView cDNA sequences:

    BX281602 AA406159 BC042547 AF285597 AW451397 BI825424 NM_031274 AI918728 
    AA406158 BM560315 

    GeneLoc Exon Structure


    Expression
    for TEX13A gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TEX13A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TEX13A expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    TestisSeminiferous TubulesSpermatidGerm Cells, Male Gametocytes
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TEX13A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TEX13A

    SOURCE GeneReport for Unigene cluster: Hs.567543

    UniProtKB/Swiss-Prot: TX13A_HUMAN, Q9BXU3
    Tissue specificity: Testis specific

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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX13A

    Orthologs
    for TEX13A gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    		   --

    ENSEMBL Gene Tree for TEX13A (if available)
    TreeFam Gene Tree for TEX13A (if available) 

    Paralogs
    for TEX13A gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TEX13A gene
    TEX13B2  
    1 SIMAP similar gene for TEX13A using alignment to 2 protein entries:     TX13A_HUMAN (see all proteins):
    TEX13B

    TEX13A for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for TEX13A
    PGOHUM00000260979 PGOHUM00000260980


    Genomic Variants
    for TEX13A gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    Locus Specific Mutation Databases (LSDB): TEX13A
    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX13A
    DNA2.0 Custom Variant and Variant Library Synthesis for TEX13A

    Disorders / Diseases
    for TEX13A gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TEX13A for disorders           About MalaCards

    TEX13A for disorders           About GeneDecksing

    OMIM gene information: 300312    OMIM disorders: --


    Export disorders for TEX13A gene to outside databases

    Publications
    for TEX13A gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TEX13A gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TEX13A)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. An abundance of X-linked genes expressed in spermatogonia. (PubMed id 11279525)1, 2, 3 Wang P.J.... Page D.C. (2001)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
    4. Molecular and cytogenetic characterization of two azoospermic patients with X-autosome translocation. (PubMed id 14531651)1 Lee S....Cha K.Y. (2003)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    External Searches for TEX13A gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing TEX13A gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56157 HGNC: 11735 AceView: TEX13A Ensembl:ENSG00000133149 euGenes: HUgn56157
    ECgene: TEX13A H-InvDB: TEX13A

    Other Databases showing TEX13A gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TEX13A gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TEX13A Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TEX13A gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TEX13A gene:
    Search GeneIP for patents involving TEX13A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for TEX13A gene

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    About This Section

     
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    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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