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Aliases for TEX12 Gene

Aliases for TEX12 Gene

  • Testis Expressed 12 2 3 5
  • Testis Expressed Sequence 12 2

External Ids for TEX12 Gene

Previous GeneCards Identifiers for TEX12 Gene

  • GC11U990274
  • GC11P113550
  • GC11P112071
  • GC11P111575
  • GC11P111543
  • GC11P112038
  • GC11P107962

Summaries for TEX12 Gene

Entrez Gene Summary for TEX12 Gene

  • This gene is similar to a mouse gene that is expressed in the testis. [provided by RefSeq, Jul 2008]

GeneCards Summary for TEX12 Gene

TEX12 (Testis Expressed 12) is a Protein Coding gene. Among its related pathways are Cell Cycle, Mitotic and Packaging Of Telomere Ends.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX12 Gene

Genomics for TEX12 Gene

Regulatory Elements for TEX12 Gene

Genomic Location for TEX12 Gene

Chromosome:
11
Start:
112,167,372 bp from pter
End:
112,172,559 bp from pter
Size:
5,188 bases
Orientation:
Plus strand

Genomic View for TEX12 Gene

Genes around TEX12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX12 Gene

Proteins for TEX12 Gene

  • Protein details for TEX12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BXU0-TEX12_HUMAN
    Recommended name:
    Testis-expressed sequence 12 protein
    Protein Accession:
    Q9BXU0
    Secondary Accessions:
    • A6NDL9
    • B0YIX3

    Protein attributes for TEX12 Gene

    Size:
    123 amino acids
    Molecular mass:
    14107 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX12 Gene

Proteomics data for TEX12 Gene at MOPED

Post-translational modifications for TEX12 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX12 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX12 Gene

Domains & Families for TEX12 Gene

Protein Domains for TEX12 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX12 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX12: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEX12 Gene

Function for TEX12 Gene

Phenotypes for TEX12 Gene

genes like me logo Genes that share phenotypes with TEX12: view

Animal Models for TEX12 Gene

MGI Knock Outs for TEX12:

Animal Model Products

miRNA for TEX12 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TEX12 Gene

Localization for TEX12 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TEX12 Gene COMPARTMENTS Subcellular localization image for TEX12 gene
Compartment Confidence
nucleus 4

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for TEX12 Gene

Pathways & Interactions for TEX12 Gene

SuperPathways for TEX12 Gene

genes like me logo Genes that share pathways with TEX12: view

Pathways by source for TEX12 Gene

3 Reactome pathways for TEX12 Gene

Interacting Proteins for TEX12 Gene

Gene Ontology (GO) - Biological Process for TEX12 Gene

None

No data available for SIGNOR curated interactions for TEX12 Gene

Drugs & Compounds for TEX12 Gene

No Compound Related Data Available

Transcripts for TEX12 Gene

mRNA/cDNA for TEX12 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1371) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TEX12 Gene

Testis expressed 12:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TEX12 Gene

No ASD Table

Relevant External Links for TEX12 Gene

GeneLoc Exon Structure for
TEX12
ECgene alternative splicing isoforms for
TEX12

Expression for TEX12 Gene

mRNA expression in normal human tissues for TEX12 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TEX12 Gene

This gene is overexpressed in Testis (x21.7).

Protein differential expression in normal tissues from HIPED for TEX12 Gene

This gene is overexpressed in Fetal ovary (49.1) and Ovary (19.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TEX12 Gene



SOURCE GeneReport for Unigene cluster for TEX12 Gene Hs.524039

mRNA Expression by UniProt/SwissProt for TEX12 Gene

Q9BXU0-TEX12_HUMAN
Tissue specificity: Testis specific.
genes like me logo Genes that share expression patterns with TEX12: view

Protein tissue co-expression partners for TEX12 Gene

- Elite partner

Primer Products

In Situ Assay Products

Orthologs for TEX12 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEX12 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TEX12 35
  • 89.97 (n)
  • 88.62 (a)
TEX12 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TEX12 35
  • 91.33 (n)
  • 89.43 (a)
TEX12 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tex12 35
  • 86.45 (n)
  • 84.55 (a)
Tex12 16
Tex12 36
  • 85 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TEX12 35
  • 100 (n)
  • 100 (a)
TEX12 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tex12 35
  • 85.91 (n)
  • 83.74 (a)
oppossum
(Monodelphis domestica)
Mammalia TEX12 36
  • 64 (a)
OneToOne
chicken
(Gallus gallus)
Aves TEX12 35
  • 58.4 (n)
  • 47.11 (a)
Species with no ortholog for TEX12:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX12 Gene

ENSEMBL:
Gene Tree for TEX12 (if available)
TreeFam:
Gene Tree for TEX12 (if available)

Paralogs for TEX12 Gene

No data available for Paralogs for TEX12 Gene

Variants for TEX12 Gene

Sequence variations from dbSNP and Humsavar for TEX12 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs360712 -- 112,169,304(-) CAATT(C/T)CTATT reference, synonymous-codon
rs360713 -- 112,168,110(-) TTGAA(A/T)GATGC intron-variant
rs756571 -- 112,170,396(-) AGAAA(A/G)CAGGT intron-variant
rs795468 -- 112,171,474(-) TGTCC(A/G)GCAGT intron-variant
rs730879 -- 112,169,987(-) TGCAG(C/T)GTTGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TEX12 Gene

Variant ID Type Subtype PubMed ID
esv2745077 CNV Deletion 23290073
nsv519192 CNV Gain 19592680

Variation tolerance for TEX12 Gene

Residual Variation Intolerance Score: 56.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.55; 11.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX12 Gene

HapMap Linkage Disequilibrium report
TEX12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX12 Gene

Disorders for TEX12 Gene

Relevant External Links for TEX12

Genetic Association Database (GAD)
TEX12
Human Genome Epidemiology (HuGE) Navigator
TEX12
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEX12

No disorders were found for TEX12 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX12 Gene

Publications for TEX12 Gene

  1. An abundance of X-linked genes expressed in spermatogonia. (PMID: 11279525) Wang P.J. … Page D.C. (Nat. Genet. 2001) 2 3 4 67
  2. Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults. (PMID: 24182552) Matteini A.M. … Walston J.D. (Cytokine 2014) 3
  3. Structural analysis of the human SYCE2-TEX12 complex provides molecular insights into synaptonemal complex assembly. (PMID: 22870393) Davies O.R. … Pellegrini L. (Open Biol 2012) 3
  4. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3
  5. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3

Products for TEX12 Gene

Sources for TEX12 Gene

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