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Aliases for TEX12 Gene

Aliases for TEX12 Gene

  • Testis Expressed 12 2 3
  • Testis Expressed Sequence 12 2

External Ids for TEX12 Gene

Previous GeneCards Identifiers for TEX12 Gene

  • GC11U990274
  • GC11P113550
  • GC11P112071
  • GC11P111575
  • GC11P111543
  • GC11P112038
  • GC11P107962

Summaries for TEX12 Gene

Entrez Gene Summary for TEX12 Gene

  • This gene is similar to a mouse gene that is expressed in the testis. [provided by RefSeq, Jul 2008]

GeneCards Summary for TEX12 Gene

TEX12 (Testis Expressed 12) is a Protein Coding gene. Among its related pathways are Cell Cycle, Mitotic and Meiosis.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX12 Gene

Genomics for TEX12 Gene

Regulatory Elements for TEX12 Gene

Genomic Location for TEX12 Gene

Start:
112,167,372 bp from pter
End:
112,172,559 bp from pter
Size:
5,188 bases
Orientation:
Plus strand

Genomic View for TEX12 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TEX12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX12 Gene

Proteins for TEX12 Gene

  • Protein details for TEX12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BXU0-TEX12_HUMAN
    Recommended name:
    Testis-expressed sequence 12 protein
    Protein Accession:
    Q9BXU0
    Secondary Accessions:
    • A6NDL9
    • B0YIX3

    Protein attributes for TEX12 Gene

    Size:
    123 amino acids
    Molecular mass:
    14107 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX12 Gene

Proteomics data for TEX12 Gene at MOPED

Post-translational modifications for TEX12 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX12 Gene

ENSEMBL proteins:
Reactome Protein details:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX12 Gene

Domains for TEX12 Gene

Protein Domains for TEX12 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEX12 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX12: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEX12 Gene

Function for TEX12 Gene

Gene Ontology (GO) - Molecular Function for TEX12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with TEX12: view

Phenotypes for TEX12 Gene

genes like me logo Genes that share phenotypes with TEX12: view

Animal Models for TEX12 Gene

MGI Knock Outs for TEX12:

Animal Model Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TEX12

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , miRNA , Transcription Factor Targeting and HOMER Transcription for TEX12 Gene

Localization for TEX12 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TEX12 Gene COMPARTMENTS Subcellular localization image for TEX12 gene
Compartment Confidence
nucleus 2
cytoskeleton 1

Gene Ontology (GO) - Cellular Components for TEX12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000795 synaptonemal complex --
GO:0000801 central element IEA --
genes like me logo Genes that share ontologies with TEX12: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TEX12 Gene

Pathways for TEX12 Gene

genes like me logo Genes that share pathways with TEX12: view

Pathways by source for TEX12 Gene

4 Reactome pathways for TEX12 Gene

Interacting Proteins for TEX12 Gene

Gene Ontology (GO) - Biological Process for TEX12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000711 meiotic DNA repair synthesis IEA --
GO:0007130 synaptonemal complex assembly IEA --
genes like me logo Genes that share ontologies with TEX12: view

Transcripts for TEX12 Gene

mRNA/cDNA for TEX12 Gene

(1371) Selected AceView cDNA sequences:
(2) Additional mRNA sequences :
(1) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TEX12 Gene

Testis expressed 12:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TEX12

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX12 Gene

No ASD Table

Relevant External Links for TEX12 Gene

GeneLoc Exon Structure for
TEX12
ECgene alternative splicing isoforms for
TEX12

Expression for TEX12 Gene

mRNA expression in normal human tissues for TEX12 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TEX12 Gene

This gene is overexpressed in Testis (21.7).

Protein differential expression in normal tissues for TEX12 Gene

This gene is overexpressed in Fetal ovary (49.1) and Ovary (19.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for TEX12 Gene

SOURCE GeneReport for Unigene cluster for TEX12 Gene Hs.524039

mRNA Expression by UniProt/SwissProt for TEX12 Gene

Q9BXU0-TEX12_HUMAN
Tissue specificity: Testis specific
genes like me logo Genes that share expressions with TEX12: view

Expression partners for TEX12 Gene

In Situ Assay Products

Orthologs for TEX12 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEX12 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TEX12 35
  • 89.97 (n)
  • 88.62 (a)
TEX12 36
  • 89 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TEX12 35
  • 91.33 (n)
  • 89.43 (a)
TEX12 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tex12 35
  • 86.45 (n)
  • 84.55 (a)
Tex12 16
Tex12 36
  • 85 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TEX12 35
  • 100 (n)
  • 100 (a)
TEX12 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tex12 35
  • 85.91 (n)
  • 83.74 (a)
oppossum
(Monodelphis domestica)
Mammalia TEX12 36
  • 64 (a)
OneToOne
chicken
(Gallus gallus)
Aves TEX12 35
  • 58.4 (n)
  • 47.11 (a)
Species with no ortholog for TEX12:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX12 Gene

ENSEMBL:
Gene Tree for TEX12 (if available)
TreeFam:
Gene Tree for TEX12 (if available)

Paralogs for TEX12 Gene

No data available for Paralogs for TEX12 Gene

Variants for TEX12 Gene

Sequence variations from dbSNP and Humsavar for TEX12 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs360712 -- 112,169,304(-) CAATT(C/T)CTATT reference, synonymous-codon
rs360713 -- 112,168,110(-) TTGAA(A/T)GATGC intron-variant
rs730879 -- 112,169,987(-) TGCAG(C/T)GTTGC intron-variant
rs756571 -- 112,170,396(-) AGAAA(A/G)CAGGT intron-variant
rs795468 -- 112,171,474(-) TGTCC(A/G)GCAGT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TEX12 Gene

Variant ID Type Subtype PubMed ID
esv2745077 CNV Deletion 23290073
nsv519192 CNV Gain 19592680

Relevant External Links for TEX12 Gene

HapMap Linkage Disequilibrium report
TEX12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX12 Gene

Disorders for TEX12 Gene

(1) University of Copenhagen DISEASES for TEX12 Gene

Relevant External Links for TEX12

Genetic Association Database (GAD)
TEX12
Human Genome Epidemiology (HuGE) Navigator
TEX12
genes like me logo Genes that share disorders with TEX12: view

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , Novoseek inferred disease relationships and Genatlas for TEX12 Gene

Publications for TEX12 Gene

  1. An abundance of X-linked genes expressed in spermatogonia. (PMID: 11279525) Wang P.J. … Page D.C. (Nat. Genet. 2001) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3 48
  4. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3
  5. Structural analysis of the human SYCE2-TEX12 complex provides molecular insights into synaptonemal complex assembly. (PMID: 22870393) Davies O.R. … Pellegrini L. (Open Biol 2012) 3

Products for TEX12 Gene

Sources for TEX12 Gene

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