TEX12 Gene
protein-coding GIFtS: 44
GCID: GC11P112038
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testis expressed 12(Previous name: testis expressed sequence 12 )
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Aliases
for TEX12 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Testis Expressed 121 2 | | Testis Expressed Sequence 121 2 | | Testis-Expressed Sequence 12 Protein2 | | Testis-Expressed Sequence 12 Protein Variant 22 | | Testis-Expressed Sequence 12 Protein Variant 32 |
Export aliases for TEX12 gene to outside databasesPrevious GC identifers: GC11U990274 GC11P113550 GC11P112071 GC11P111575 GC11P111543 GC11P107962 |
Summaries
for TEX12 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TEX12:
This gene is similar to a mouse gene that is expressed in the testis. (provided by RefSeq, Jul 2008)
|
Genomic Views
for TEX12 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_033899.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TEX12 gene promoter:
TBP ATF-2 IRF-7A NF-kappaB NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for TEX12
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX12 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q22 Ensembl cytogenetic band: 11q23.1 HGNC chromosome: 11TEX12 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P112038: view genomic region
(about GC identifiers)
Start:
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112,038,095 bp from pter |
End:
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112,043,282 bp from pter |
Size:
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5,188 bases |
Orientation:
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plus strand |
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Proteins
for TEX12 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TEX12_HUMAN, Q9BXU0 (See
protein sequence)Recommended Name: Testis-expressed sequence 12 protein Size: 123 amino acids; 14107 Da
Secondary accessions: A6NDL9 B0YIX3Explore the universe of human proteins at neXtProt for TEX12: NX_Q9BXU0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BXU0
TEX12 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_112565.1
ENSEMBL proteins: ENSP00000436893 ENSP00000280358 Reactome Protein details: Q9BXU0
Human Recombinant Protein Products for TEX12:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000795 | synaptonemal complex |
IEA | -- |
TEX12 for ontologies About GeneDecksing
TEX12 Antibody Products:
Assay Products for TEX12: |
Protein
Domains /
Families
for TEX12 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q9BXU0 |
Function
for TEX12 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005515 | protein binding |
-- | -- |
TEX12 for ontologies About GeneDecksing
Phenotypes:
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Tex12):
TEX12 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Tex12tm1Hoog for TEX12
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX12 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX12
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TEX12 (NM_031275) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX12 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX12 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX12 |
|
Pathways & Interactions
for TEX12 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Meiotic Synapsis | | | 2 | Synapsis | | | 3 | Cell Cycle | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 
Reactome Pathways for TEX12
TEX12 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEX12
STRING Interaction
Network Preview (showing 5 interactants - click image to see 22)
5/22 Interacting proteins for TEX12 (ENSP000002803584) via UniProtKB, MINT, STRING, and/or I2D (see all 22)About this table
|
Drugs & Compounds
for TEX12 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TEX12
Search CenterWatch for drugs/clinical trials and news about TEX12
|
Transcripts
for TEX12 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TEX12 gene: NM_031275.4 Unigene Cluster for TEX12: Testis expressed 12 Hs.524039 [show with all ESTs]Unigene Representative Sequence: BC0295062 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000530752 ENST00000280358(uc001pnc.3 uc001pnd.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX12 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX12
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TEX12 (NM_031275) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX12 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX12 |
Additional cDNA sequence: AF285600.1 BC029506.1 2 DOTS entries: DT.40119013 DT.97801556 24/1371 AceView cDNA sequences (see all 1371): BU660434 NM_031938 BE905245 CB157471 AA298733 BM823116 BQ229571 CB269669 AJ709307 AA421012 CB162567 AA315473 BG569394 BM476425 BC015188 BU839269 CA947141 BX354210 BQ962548 BE207116 AA302990 BG106140 BX476384 BG741173
GeneLoc Exon Structure
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Expression
for TEX12 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TEX12 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AACTACGTCA
About this image
See TEX12 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TEX12
SOURCE GeneReport for Unigene cluster: Hs.524039
UniProtKB/Swiss-Prot: TEX12_HUMAN, Q9BXU0Tissue specificity: Testis specific
SABiosciences Custom PCR Arrays for TEX12
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX12
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TEX12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX12 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX12 |
Orthologs
for TEX12 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TEX12 gene from 2/7 species (see all 7) About this table
ENSEMBL Gene Tree for TEX12 (if available)
TreeFam Gene Tree for TEX12 (if available) |
Paralogs
for TEX12 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TEX12 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TEX12 (112038095 - 112043282 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TEX12: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX12 |
|
Disorders
/ Diseases
for TEX12 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
 TEX12 for disorders About MalaCards
TEX12 for disorders About GeneDecksing
OMIM gene information: 605791
OMIM disorders: --
1 disease from the University of Copenhagen DISEASES database for TEX12:Infertility Human Genome Epidemiology (HuGE) Navigator: TEX12 (1 document)
Export disorders for TEX12 gene to outside databases
|
Publications
for TEX12 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TEX12 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TEX12) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- An abundance of X-linked genes expressed in spermatogonia. (PubMed id 11279525)1, 2, 3 Wang P.J.... Page D.C. (2001)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PubMed id 20967262)1 Prakash T....Taylor T.D. (2010)
- Association between genetic variants in VEGF, ERCC3 a nd occupational benzene haematotoxicity. (PubMed id 19773279)1 Hosgood H.D....Lan Q. (2009)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- Human chromosome 11 DNA sequence and analysis including novel gene identification. (PubMed id 16554811)2 Taylor T.D....Sakaki Y. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for TEX12 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing TEX12 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TEX12 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TEX12 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TEX12 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TEX12 gene:
Search GeneIP for patents involving TEX12
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TEX12 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TEX12 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TEX12 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX12 | | | OriGene Protein Over-expression Lysate for TEX12 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TEX12 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX12 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX12 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TEX12 | | OriGene Custom Protein Services for TEX12 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TEX12 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX12 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX12 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEX12 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX12 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX12 |
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 |  |  |  | |
| | | | Search Tocris compounds for TEX12 |
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 | | | TEX12 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX12 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for TEX12 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX12 |
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