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Aliases for TEX12 Gene

Aliases for TEX12 Gene

  • Testis Expressed 12 2 3 5
  • Testis Expressed Sequence 12 2

External Ids for TEX12 Gene

Previous GeneCards Identifiers for TEX12 Gene

  • GC11U990274
  • GC11P113550
  • GC11P112071
  • GC11P111575
  • GC11P111543
  • GC11P112038
  • GC11P107962

Summaries for TEX12 Gene

Entrez Gene Summary for TEX12 Gene

  • This gene is similar to a mouse gene that is expressed in the testis. [provided by RefSeq, Jul 2008]

GeneCards Summary for TEX12 Gene

TEX12 (Testis Expressed 12) is a Protein Coding gene. Among its related pathways are Cell Cycle, Mitotic and Meiosis.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX12 Gene

Genomics for TEX12 Gene

Regulatory Elements for TEX12 Gene

Enhancers for TEX12 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G112119 1.4 FANTOM5 Ensembl ENCODE 11.3 -46.5 -46502 3.1 BCOR PKNOX1 ZNF146 JUN ZMYM3 GATA2 EED FOS JUNB CEBPB IL18 TIMM8B SDHD TEX12 BCO2 LOC101928847 ALG9
GH11G112289 1.5 Ensembl ENCODE dbSUPER 9.4 +124.7 124671 4.8 ATF1 ARNT CREB3L1 SIN3A FEZF1 GLIS2 GATA2 ZNF143 ZNF207 KLF7 LOC283140 RNU6-44P TEX12 PIH1D2 C11orf57 BCO2 GC11M112270 GC11P112339
GH11G112128 1 Ensembl ENCODE 11.3 -38.3 -38290 2.2 KLF1 NFIB JUN KLF17 FOSL1 GATA3 ZBTB48 FOS PRDM10 TCF7L2 BCO2 IL18 TEX12 ENSG00000254638 SDHD TIMM8B C11orf57 PIH1D2 CRYAB HSPB2
GH11G112240 1.1 ENCODE dbSUPER 10.1 +74.1 74075 2.1 FOXA2 RCOR1 ZNF680 ZBTB11 ZNF426 CEBPB ZNF623 ZNF781 ZNF518A ZNF555 TEX12 PIH1D2 LOC101928847 RNU6-44P BCO2 RPS6P16 LOC100132686
GH11G112195 0.7 ENCODE 10.8 +28.7 28735 0.8 TBP KLF1 CEBPB KLF4 RAD21 EP300 BRCA1 RFX5 MAFF ZNF512 BCO2 ENSG00000254638 TEX12 SDHD TIMM8B RNU6-44P MRPS36P4 KCTD9P4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TEX12 on UCSC Golden Path with GeneCards custom track

Genomic Location for TEX12 Gene

112,167,372 bp from pter
112,172,559 bp from pter
5,188 bases
Plus strand

Genomic View for TEX12 Gene

Genes around TEX12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX12 Gene

Proteins for TEX12 Gene

  • Protein details for TEX12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Testis-expressed protein 12
    Protein Accession:
    Secondary Accessions:
    • A6NDL9
    • B0YIX3

    Protein attributes for TEX12 Gene

    123 amino acids
    Molecular mass:
    14107 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEX12 Gene

Post-translational modifications for TEX12 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEX12 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX12 Gene

Domains & Families for TEX12 Gene

Protein Domains for TEX12 Gene


Suggested Antigen Peptide Sequences for TEX12 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEX12: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEX12 Gene

Function for TEX12 Gene

Phenotypes for TEX12 Gene

genes like me logo Genes that share phenotypes with TEX12: view

Animal Models for TEX12 Gene

MGI Knock Outs for TEX12:

Animal Model Products

CRISPR Products

miRNA for TEX12 Gene

Inhibitory RNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TEX12 Gene

Localization for TEX12 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEX12 gene
Compartment Confidence
nucleus 4

Gene Ontology (GO) - Cellular Components for TEX12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000801 central element IBA --
genes like me logo Genes that share ontologies with TEX12: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TEX12 Gene

Pathways & Interactions for TEX12 Gene

SuperPathways for TEX12 Gene

SuperPathway Contained pathways
1 Meiosis
2 Cell Cycle, Mitotic
genes like me logo Genes that share pathways with TEX12: view

Pathways by source for TEX12 Gene

3 Reactome pathways for TEX12 Gene

Interacting Proteins for TEX12 Gene

Gene Ontology (GO) - Biological Process for TEX12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000711 meiotic DNA repair synthesis IEA --
GO:0007130 synaptonemal complex assembly IBA --
genes like me logo Genes that share ontologies with TEX12: view

No data available for SIGNOR curated interactions for TEX12 Gene

Drugs & Compounds for TEX12 Gene

No Compound Related Data Available

Transcripts for TEX12 Gene

mRNA/cDNA for TEX12 Gene

(1) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(1371) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TEX12 Gene

Testis expressed 12:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEX12 Gene

No ASD Table

Relevant External Links for TEX12 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TEX12 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TEX12 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TEX12 Gene

This gene is overexpressed in Testis (x21.7).

Protein differential expression in normal tissues from HIPED for TEX12 Gene

This gene is overexpressed in Fetal ovary (49.1) and Ovary (19.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for TEX12 Gene

Protein tissue co-expression partners for TEX12 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TEX12 Gene:


SOURCE GeneReport for Unigene cluster for TEX12 Gene:


mRNA Expression by UniProt/SwissProt for TEX12 Gene:

Tissue specificity: Testis specific.
genes like me logo Genes that share expression patterns with TEX12: view

Primer Products

No data available for Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEX12 Gene

Orthologs for TEX12 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEX12 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TEX12 34 35
  • 100 (n)
(Canis familiaris)
Mammalia TEX12 34 35
  • 91.33 (n)
(Bos Taurus)
Mammalia TEX12 34 35
  • 89.97 (n)
(Mus musculus)
Mammalia Tex12 34 16 35
  • 86.45 (n)
(Rattus norvegicus)
Mammalia Tex12 34
  • 85.91 (n)
(Monodelphis domestica)
Mammalia TEX12 35
  • 64 (a)
(Gallus gallus)
Aves TEX12 34
  • 58.4 (n)
Species where no ortholog for TEX12 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX12 Gene

Gene Tree for TEX12 (if available)
Gene Tree for TEX12 (if available)

Paralogs for TEX12 Gene

No data available for Paralogs for TEX12 Gene

Variants for TEX12 Gene

Sequence variations from dbSNP and Humsavar for TEX12 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000638355 -- 112,172,351(+) TGAAA(-/T)TTTTT utr-variant-3-prime
rs1000974740 -- 112,172,244(+) AGTGT(C/T)TCTGA utr-variant-3-prime
rs1000987659 -- 112,172,046(+) CTCCT(C/T)GAATT utr-variant-3-prime
rs1001115507 -- 112,165,457(+) GTGAT(C/T)AGAAG nc-transcript-variant, upstream-variant-2KB
rs1001346612 -- 112,166,485(+) TTTAA(A/T)CAAGC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TEX12 Gene

Variant ID Type Subtype PubMed ID
esv2745077 CNV deletion 23290073
nsv519192 CNV gain 19592680

Variation tolerance for TEX12 Gene

Residual Variation Intolerance Score: 56.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.55; 11.97% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEX12 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEX12 Gene

Disorders for TEX12 Gene

Relevant External Links for TEX12

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TEX12 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX12 Gene

Publications for TEX12 Gene

  1. An abundance of X-linked genes expressed in spermatogonia. (PMID: 11279525) Wang P.J. … Page D.C. (Nat. Genet. 2001) 2 3 4 64
  2. Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. (PMID: 19773279) Hosgood H.D. … Lan Q. (Occup Environ Med 2009) 3 46 64
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  4. Novel gene variants predict serum levels of the cytokines IL-18 and IL-1ra in older adults. (PMID: 24182552) Matteini A.M. … Walston J.D. (Cytokine 2014) 3 64
  5. Structural analysis of the human SYCE2-TEX12 complex provides molecular insights into synaptonemal complex assembly. (PMID: 22870393) Davies O.R. … Pellegrini L. (Open Biol 2012) 3 64

Products for TEX12 Gene

Sources for TEX12 Gene

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