TEX11 Gene
protein-coding GIFtS: 49
GCID: GC0XM069748
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testis expressed 11(Previous name: testis expressed sequence 11 )
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Aliases
for TEX11 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Testis Expressed 111 2 | | TGC11 2 | | TSGA31 2 | | Testis Expressed Sequence 111 2 | | Testis-Expressed Sequence 11 Protein2 |
Export aliases for TEX11 gene to outside databasesPrevious GC identifers: GC0XM065926 GC0XM067226 GC0XM067982 GC0XM068615 GC0XM069531 GC0XM069665 GC0XM063570 |
Summaries
for TEX11 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TEX11:
This gene is X-linked and is expressed in only male germ cells. Two alternatively spliced transcript variants encodingdistinct isoforms have been found for this gene. (provided by RefSeq, Jul 2008)
|
Genomic Views
for TEX11 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_011669.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TEX11 gene promoter:
Brachyury FOXD3 NRSF form 2 AREB6 FOXC1 Nkx6-1 POU2F1 POU2F1a FOXJ2 (long isoform) FOXJ2
Other transcription factors
Search SABiosciences Chromatin IP Primers for TEX11
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX11 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq13.1 Ensembl cytogenetic band: Xq13.1 HGNC cytogenetic band: Xp11TEX11 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM069748: view genomic region
(about GC identifiers)
Start:
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69,748,790 bp from pter |
End:
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70,128,581 bp from pter |
Size:
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379,792 bases |
Orientation:
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minus strand |
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Proteins
for TEX11 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TEX11_HUMAN, Q8IYF3 (See
protein sequence)Recommended Name: Testis-expressed sequence 11 protein Size: 940 amino acids; 107889 Da
Sequence caution: Sequence=AAK31973.1; Type=Erroneous initiation; Sequence=CAI39958.1; Type=Erroneous initiation;Sequence=CAI40155.1; Type=Erroneous initiation; Sequence=CAI41496.1; Type=Erroneous initiation;
Secondary accessions: A8K8V6 Q5JQQ8 Q96LZ4 Q96M47 Q9BXU6Alternative splicing: 3 isoforms: Q8IYF3-1 Q8IYF3-2 Q8IYF3-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for TEX11: NX_Q8IYF3
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8IYF3
TEX11 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001003811.1 NP_112566.2
ENSEMBL proteins: ENSP00000363453 ENSP00000379226 ENSP00000363440 ENSP00000340995
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000794 | condensed nuclear chromosome |
-- | -- | | GO:0000801 | central element |
IEA | -- |
TEX11 for ontologies About GeneDecksing
TEX11 Antibody Products:
Assay Products for TEX11: |
Protein
Domains /
Families
for TEX11 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TEX11 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8IYF3ProtoNet protein and cluster: Q8IYF3 |
Function
for TEX11 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX11 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX11 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TEX11 (NM_001003811) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX11 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX11 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX11 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
TEX11 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for TEX11:
Animal Models:
Mouse knock-out Tex11tm1.1Jpt for TEX11
4 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Tex11):
TEX11 for phenotypes About GeneDecksing
|
Pathways & Interactions
for TEX11 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEX11
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/45 Interacting proteins for TEX11 (Q8IYF31, 2, 3 ENSP000003409954) via UniProtKB, MINT, STRING, and/or I2D (see all 45)| Interactant | Interaction Details |
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| GeneCard | External ID(s) |
|---|
| LIN37 | Q96GY31, 2, 3, ENSP000003011594 | EBI-742397,EBI-748884 MINT-67376 I2D:
score=6 STRING: ENSP00000301159 | | MAD1L1 | Q9Y6D92, 3, ENSP000003825624 | MINT-66279 I2D:
score=5 STRING: ENSP00000382562 | | SNX7 | Q9UNH62, 3, ENSP000003044294 | MINT-68351 I2D:
score=5 STRING: ENSP00000304429 | | TSC22D4 | Q9Y3Q82, 3, ENSP000003001814 | MINT-66758 I2D:
score=5 STRING: ENSP00000300181 | | CCDC11 | Q96M912, 3, ENSP000003815534 | MINT-66836 I2D:
score=4 STRING: ENSP00000381553 |
About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000712 | resolution of meiotic recombination intermediates |
IEA | -- | | GO:0007060 | male meiosis chromosome segregation |
IEA | -- | | GO:0007130 | synaptonemal complex assembly |
IEA | -- | | GO:0007140 | male meiosis |
-- | -- | | GO:0008584 | male gonad development |
IEA | -- |
TEX11 for ontologies About GeneDecksing
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Drugs & Compounds
for TEX11 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TEX11
Search CenterWatch for drugs/clinical trials and news about TEX11
|
Transcripts
for TEX11 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TEX11 gene (2 alternative transcripts): NM_001003811.1 NM_031276.2 Unigene Cluster for TEX11: Testis expressed 11 Hs.121776 [show with all ESTs]Unigene Representative Sequence: NM_0010038114 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000374333(uc004dym.3) ENST00000395889(uc004dyl.3) ENST00000374320(uc004dyk.3)
ENST00000344304
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX11 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX11 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): TEX11 (NM_001003811) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX11 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX11 |
Additional cDNA sequence: AF285594.1 AK057391.1 AK057523.1 AK292471.1 BC036016.1 4 DOTS entries: DT.100018091 DT.204933 DT.100749772 DT.100018092 1 AceView cDNA sequence: BG722191
GeneLoc Exon Structure
|
Expression
for TEX11 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TEX11 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGAAGATAC
About this image
See TEX11 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TEX11
SOURCE GeneReport for Unigene cluster: Hs.121776
SABiosciences Custom PCR Arrays for TEX11
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX11
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TEX11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX11 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX11 |
Orthologs
for TEX11 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TEX11 gene from 6/15 species (see all 15) About this table
ENSEMBL Gene Tree for TEX11 (if available)
TreeFam Gene Tree for TEX11 (if available) |
Paralogs
for TEX11 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TEX11 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TEX11 (69748790 - 69998790 bp, first 250kb of TEX11)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 14 variations for TEX11
8 CNVs: 7797 53032 53031 53030 53033 53027 53028 53029
6 Indels: 83581 96742 96744 83580 96743 83579
Locus Specific Mutation Databases (LSDB): TEX11
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX11 |
|
Disorders
/ Diseases
for TEX11 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TEX11 for disorders About GeneDecksing
OMIM gene information: 300311
OMIM disorders: --
2  diseases for TEX11: About MalaCardsazoospermia ataxia
1 disease from the University of Copenhagen DISEASES database for TEX11:Male infertility Human Genome Epidemiology (HuGE) Navigator: TEX11 (1 document)
Export disorders for TEX11 gene to outside databases
|
Publications
for TEX11 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TEX11 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TEX11) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- An abundance of X-linked genes expressed in spermatogonia. (PubMed id 11279525)1, 2, 3 Wang P.J.... Page D.C. (2001)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- Evaluation of 172 candidate polymorphisms for associa tion with oligozoospermia or azoospermia in a large cohort of men of European d escent. (PubMed id 20378615)1 Aston K.I....Carrell D.T. (2010)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)1 Lim J.... Zoghbi H.Y. (2006)
- The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
- Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)1 Rual J.F....Vidal M. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
- Creation of genome-wide protein expression libraries using random activation of gene expression. (PubMed id 11329013)1 Harrington J.J.... Ducar M. (2001)
|
External Searches for TEX11 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TEX11 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TEX11 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TEX11 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TEX11 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TEX11 gene:
Search GeneIP for patents involving TEX11
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TEX11 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TEX11 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TEX11 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX11 | | | OriGene Protein Over-expression Lysate for TEX11 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TEX11 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX11 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX11 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for TEX11 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TEX11 | | OriGene Custom Protein Services for TEX11 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TEX11 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX11 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX11 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEX11 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX11 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX11 |
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 |  |  |  | |
| | | | Search Tocris compounds for TEX11 |
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 | | | TEX11 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX11 |
|  |  |  | | | | Search ThermoFisher Antibodies for TEX11 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX11 |
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