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Aliases for TEX101 Gene

Aliases for TEX101 Gene

  • Testis Expressed 101 2 3 5
  • Spermatogenesis-Related Gene Protein 3 4
  • Scleroderma-Associated Autoantigen 3 4
  • Spermatogenesis Associated 44 2 3
  • Testis Expressed Sequence 101 2 3
  • Cell Surface Receptor NYD-SP8 3 4
  • Cancer/Testis Antigen 131 2 3
  • SGRG 3 4
  • Testis-Specific Protein TES101RP 3
  • Testis-Expressed Protein 101 3
  • TES101RP 3
  • GTPR867 3
  • NYD-SP8 3
  • PRO1884 3
  • SPATA44 3
  • CT131 3

External Ids for TEX101 Gene

Previous GeneCards Identifiers for TEX101 Gene

  • GC00U920630
  • GC19P048585
  • GC19P043892
  • GC19P040326

Summaries for TEX101 Gene

GeneCards Summary for TEX101 Gene

TEX101 (Testis Expressed 101) is a Protein Coding gene. An important paralog of this gene is LYPD4.

UniProtKB/Swiss-Prot for TEX101 Gene

  • May play a role in signal transduction and promote protein tyrosine phosphorylation.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEX101 Gene

Genomics for TEX101 Gene

Regulatory Elements for TEX101 Gene

Enhancers for TEX101 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TEX101 on UCSC Golden Path with GeneCards custom track

Genomic Location for TEX101 Gene

43,388,611 bp from pter
43,418,615 bp from pter
30,005 bases
Plus strand

Genomic View for TEX101 Gene

Genes around TEX101 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEX101 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEX101 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEX101 Gene

Proteins for TEX101 Gene

  • Protein details for TEX101 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Testis-expressed sequence 101 protein
    Protein Accession:
    Secondary Accessions:
    • Q7L5R2
    • Q9BPY7

    Protein attributes for TEX101 Gene

    249 amino acids
    Molecular mass:
    26667 Da
    Quaternary structure:
    • Interacts with VAMP3.

    Alternative splice isoforms for TEX101 Gene


neXtProt entry for TEX101 Gene

Proteomics data for TEX101 Gene at MOPED

Post-translational modifications for TEX101 Gene

Other Protein References for TEX101 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEX101 Gene

Domains & Families for TEX101 Gene

Gene Families for TEX101 Gene

Protein Domains for TEX101 Gene


Suggested Antigen Peptide Sequences for TEX101 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 UPAR/Ly6 domain.
  • Contains 1 UPAR/Ly6 domain.
genes like me logo Genes that share domains with TEX101: view

Function for TEX101 Gene

Molecular function for TEX101 Gene

UniProtKB/Swiss-Prot Function:
May play a role in signal transduction and promote protein tyrosine phosphorylation.
genes like me logo Genes that share phenotypes with TEX101: view

Animal Models for TEX101 Gene

MGI Knock Outs for TEX101:

Animal Model Products

miRNA for TEX101 Gene

miRTarBase miRNAs that target TEX101

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TEX101 Gene

Localization for TEX101 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEX101 Gene

Cell membrane; Lipid-anchor, GPI-anchor. Note=Associated with lipid rafts. {ECO:0000250}.

Subcellular locations from

Jensen Localization Image for TEX101 Gene COMPARTMENTS Subcellular localization image for TEX101 gene
Compartment Confidence
plasma membrane 5

Gene Ontology (GO) - Cellular Components for TEX101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002080 acrosomal membrane IEA --
GO:0031225 anchored component of membrane IEA --
genes like me logo Genes that share ontologies with TEX101: view

Pathways & Interactions for TEX101 Gene

SuperPathways for TEX101 Gene

No Data Available

Interacting Proteins for TEX101 Gene

Gene Ontology (GO) - Biological Process for TEX101 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002696 positive regulation of leukocyte activation IEA --
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IEA --
genes like me logo Genes that share ontologies with TEX101: view

No data available for Pathways by source and SIGNOR curated interactions for TEX101 Gene

Drugs & Compounds for TEX101 Gene

No Compound Related Data Available

Transcripts for TEX101 Gene

Unigene Clusters for TEX101 Gene

Testis expressed 101:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TEX101 Gene

No ASD Table

Relevant External Links for TEX101 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TEX101 Gene

mRNA expression in normal human tissues for TEX101 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TEX101 Gene

This gene is overexpressed in Testis (x49.0).

Protein differential expression in normal tissues from HIPED for TEX101 Gene

This gene is overexpressed in Testis (52.6) and Ovary (16.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TEX101 Gene

SOURCE GeneReport for Unigene cluster for TEX101 Gene Hs.97978

mRNA Expression by UniProt/SwissProt for TEX101 Gene

Tissue specificity: Detected in testis and spermatogonia. Not detected in spermatocytes. Detected in blood leukocytes.
genes like me logo Genes that share expression patterns with TEX101: view

Protein tissue co-expression partners for TEX101 Gene

- Elite partner

Primer Products

Orthologs for TEX101 Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for TEX101 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TEX101 35
  • 69.99 (n)
  • 54.55 (a)
TEX101 36
  • 52 (a)
(Canis familiaris)
Mammalia TEX101 35
  • 72.62 (n)
  • 60 (a)
TEX101 36
  • 59 (a)
(Mus musculus)
Mammalia Tex101 35
  • 67.1 (n)
  • 55.84 (a)
Tex101 16
Tex101 36
  • 54 (a)
(Pan troglodytes)
Mammalia TEX101 35
  • 99 (n)
  • 97.75 (a)
TEX101 36
  • 95 (a)
(Rattus norvegicus)
Mammalia Tex101 35
  • 64.78 (n)
  • 51.01 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 33 (a)
Alicante grape
(Vitis vinifera)
eudicotyledons Vvi.7403 35
Species with no ortholog for TEX101:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEX101 Gene

Gene Tree for TEX101 (if available)
Gene Tree for TEX101 (if available)

Paralogs for TEX101 Gene

Paralogs for TEX101 Gene

(1) SIMAP similar genes for TEX101 Gene using alignment to 1 proteins: Pseudogenes for TEX101 Gene

genes like me logo Genes that share paralogs with TEX101: view

Variants for TEX101 Gene

Sequence variations from dbSNP and Humsavar for TEX101 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs35033974 - 43,416,460(+) TCCCG(G/T)CCTGA reference, missense
rs12976187 -- 43,398,010(+) tatat(A/T)aaaat intron-variant
rs12976581 -- 43,405,397(+) ATATA(A/G)TGAAA intron-variant
rs12976609 -- 43,389,433(+) TTCTG(C/G)ACTCC intron-variant
rs12976861 -- 43,405,506(+) GCAGA(A/G)GTTGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TEX101 Gene

Variant ID Type Subtype PubMed ID
dgv1087e1 CNV Complex 17122850
essv22369 CNV CNV 17122850
nsv469666 CNV Complex 16826518
nsv520852 CNV Gain+Loss 19592680
esv1342569 CNV Deletion 17803354
nsv509744 CNV Insertion 20534489

Variation tolerance for TEX101 Gene

Residual Variation Intolerance Score: 60.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.90; 59.30% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TEX101 Gene

Disorders for TEX101 Gene

Relevant External Links for TEX101

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TEX101 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEX101 Gene

Publications for TEX101 Gene

  1. A novel spermatogenesis-specific uPAR gene expressed in human and mouse testis. (PMID: 16516155) Teng X. … Kong X. (Biochem. Biophys. Res. Commun. 2006) 2 3 4 67
  2. TEX101 is shed from the surface of sperm located in the caput epididymidis of the mouse. (PMID: 16388701) Takayama T. … Takizawa T. (Zygote 2005) 2 3
  3. The contribution of common genetic variation to nicotine and cotinine glucuronidation in multiple ethnic/racial populations. (PMID: 25293881) Patel Y.M. … Murphy S.E. (Cancer Epidemiol. Biomarkers Prev. 2015) 3
  4. Transcriptome analysis of the cancer/testis genes, DAZ1, AURKC, and TEX101, in breast tumors and six breast cancer cell lines. (PMID: 25994570) Mobasheri M.B. … Modarressi M.H. (Tumour Biol. 2015) 3
  5. Differential diagnosis of azoospermia with proteomic biomarkers ECM1 and TEX101 quantified in seminal plasma. (PMID: 24259048) Drabovich A.P. … Diamandis E.P. (Sci Transl Med 2013) 3

Products for TEX101 Gene

Sources for TEX101 Gene