TEX101 Gene
protein-coding GIFtS: 43
GCID: GC19P043892
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|
testis expressed 101(Previous name: testis expressed sequence 101 )
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Aliases
for TEX101 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Testis Expressed 1011 2 | | MGC47661 | | SGRG1 2 3 5 | | GTPR8672 | | CT1311 2 | | NYD-SP82 | | Testis Expressed Sequence 1011 2 | | PRO18842 | | Cell Surface Receptor NYD-SP82 3 | | Cancer/Testis Antigen 1312 | | Scleroderma-Associated Autoantigen2 3 | | Testis-Expressed Protein 1012 | | Spermatogenesis-Related Gene Protein2 3 | | Testis-Expressed Sequence 101 Protein2 | | TES101RP2 5 | | Testis-Specific Protein TES101RP2 |
Export aliases for TEX101 gene to outside databasesPrevious GC identifers: GC00U920630 GC19P048585 GC19P040326 |
Summaries
for TEX101 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: TX101_HUMAN, Q9BY14Function: May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity)
|
Genomic Views
for TEX101 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TEX101 gene promoter:
SRF p53 GATA-3 GCNF SRF (504 AA) FOXD1 GCNF-1 GCNF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for TEX101
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX101 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.31 Ensembl cytogenetic band: 19q13.31 HGNC cytogenetic band: 19q13.31TEX101 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19P043892: view genomic region
(about GC identifiers)
Start:
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43,892,763 bp from pter |
End:
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43,922,767 bp from pter |
Size:
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30,005 bases |
Orientation:
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plus strand |
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Proteins
for TEX101 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TX101_HUMAN, Q9BY14 (See
protein sequence)Recommended Name: Testis-expressed sequence 101 protein precursor Size: 249 amino acids; 26667 Da
Subunit: Interacts with VAMP3 (By similarity)
Subcellular location: Cell membrane; Lipid-anchor, GPI-anchor (By similarity). Note=Associated with lipid rafts (Bysimilarity)
Secondary accessions: Q7L5R2 Q9BPY7Alternative splicing: 2 isoforms: Q9BY14-1 Q9BY14-2 (Variant in position: 4:R->M (in dbSNP:rs17849541))Explore the universe of human proteins at neXtProt for TEX101: NX_Q9BY14
Post-translational modifications:
N-glycosylated (By similarity)1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BY14
TEX101 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001123483.1 NP_113639.4
ENSEMBL proteins: ENSP00000253435
Human Recombinant Protein Products for TEX101:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
TEX101 for ontologies About GeneDecksing
TEX101 Antibody Products:
Assay Products for TEX101: |
Protein
Domains /
Families
for TEX101 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TEX101 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9BY14ProtoNet protein and cluster: Q9BY14 1 Blocks protein family: IPB001526 CD59 antigen
UniProtKB/Swiss-Prot: TX101_HUMAN, Q9BY14Similarity: Contains 1 UPAR/Ly6 domain |
Function
for TEX101 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: TX101_HUMAN, Q9BY14Function: May play a role in signal transduction and promote protein tyrosine phosphorylation (By similarity)Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX101 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX101 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TEX101 (NM_001130011) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX101 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX101 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX101 |
|
Pathways & Interactions
for TEX101 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEX101
|
Drugs & Compounds
for TEX101 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TEX101
Search CenterWatch for drugs/clinical trials and news about TEX101 / TX101
|
Transcripts
for TEX101 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TEX101 gene (2 alternative transcripts): NM_001130011.1 NM_031451.4 Unigene Cluster for TEX101: Testis expressed 101 Hs.97978 [show with all ESTs]Unigene Representative Sequence: AF2412681 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000253435(uc002owk.3 uc010xwo.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX101 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX101 (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): TEX101 (NM_001130011) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEX101 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX101 |
Additional cDNA sequence: AF241268.1 AF353396.1 AY014285.1 AY359077.1 BC001861.2 4 DOTS entries: DT.110914 DT.110915 DT.100744616 DT.95302089 24/43 AceView cDNA sequences (see all 43): AY359077 AA417291 CD360001 AA960901 AA953495 BM716836 AA405709 BM674514 BC001861 BI829445 BM701462 BM559890 AY014285 AI005430 BM553361 AA971007 BI464375 BI825558 BI548314 AW665972 AI149970 BM559583 AA405957 AW469755
GeneLoc Exon Structure
|
Expression
for TEX101 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TEX101 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTGTGGAAG
About this image
See TEX101 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TEX101
SOURCE GeneReport for Unigene cluster: Hs.97978
UniProtKB/Swiss-Prot: TX101_HUMAN, Q9BY14Tissue specificity: Detected in testis and spermatogonia. Not detected in spermatocytes. Detected in blood leukocytes
SABiosciences Custom PCR Arrays for TEX101
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX101
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TEX101 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX101 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX101 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX101 |
Orthologs
for TEX101 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for TEX101 gene from 2/6 species (see all 6) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Tex1011 , 5 |
testis expressed gene 1011, 5 |
66.94(n)1
55.87(a)1 |
|
7 (12.13 cM)5
567461 NM_019981.21 NP_064365.11
246680125 |
Alicante grape
(Vitis vinifera) |
eudicotyledons |
Vvi.74032 |
Vitis vinifera transcribed sequences |
78.64(n) |
|
BQ793166.1 |
ENSEMBL Gene Tree for TEX101 (if available)
TreeFam Gene Tree for TEX101 (if available) |
Paralogs
for TEX101 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TEX101 gene
- CD1772 CD177P12 LYPD42
1 SIMAP similar gene for TEX101 using alignment to 1 protein entry: TX101_HUMAN:CD177
TEX101 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for TEX101
PGOHUM00000241905
|
Genomic Variants
for TEX101 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TEX101 (43892763 - 43922767 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for TEX101
2 CNVs: 50177 4082 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX101 |
|
Disorders
/ Diseases
for TEX101 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TEX101 for disorders About GeneDecksing
OMIM gene information: 612665
OMIM disorders: --
3  diseases for TEX101: About MalaCardsscleroderma basal cell carcinoma carcinoma
Export disorders for TEX101 gene to outside databases
|
Publications
for TEX101 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TEX101 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with TEX101) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A novel spermatogenesis-specific uPAR gene expressed in human and mouse testis. (PubMed id 16516155)1, 2, 3 Teng X....Kong X. (2006)
- TEX101 is shed from the surface of sperm located in the caput epididymidis of the mouse. (PubMed id 16388701)1, 3 Takayama T....Takizawa T. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Expression of testis-specific genes, TEX101 and ODF4, in chronic myeloid leukemia and evaluation of TEX101 immunogenicity. (PubMed id 22588436)1 Ghafouri-Fard S....Yazarloo F. (2012)
- Preparation of anti-NYD-SP8 rabbit polyclonal antibody and its application in the analysis of NYD-SP8 expression in nasopharyngeal car cinoma cell lines and clinical tissues. (PubMed id 22158499)1 Yang L.L....Xia Y.F. (2011)
- Verification of male infertility biomarkers in seminal plasma by multiplex selected reaction monitoring assay. (PubMed id 21933954)1 Drabovich A.P....Diamandis E.P. (2011)
- Elevated expression levels of testis-specific genes T EX101 and SPATA19 in basal cell carcinoma and their correlation with clinical a nd pathological features. (PubMed id 19886887)1 Ghafouri-Fard S....Modarressi M.H. (2010)
- A sperm GPI-anchored protein elicits sperm-cumulus cross-talk leading to the acrosome reaction. (PubMed id 19153666)1 Yin L....Chan H.C. (2009)
|
External Searches for TEX101 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TEX101 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TEX101 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TEX101 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TEX101 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TEX101 gene:
Search GeneIP for patents involving TEX101
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TEX101 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TEX101 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TEX101 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEX101 | | | OriGene Protein Over-expression Lysate for TEX101 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TEX101 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEX101 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEX101 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TEX101 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEX101 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEX101 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEX101 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEX101 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEX101 |
| |
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| | | | Search Tocris compounds for TEX101 |
| |  |  |  |  | | | | |
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 |
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 | | | TEX101 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX101 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for TEX101 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX101 |
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