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TEX10 Gene

protein-coding   GIFtS: 49
GCID: GC09M103064

Testis Expressed 10

(Previous names: testis expressed gene 10, testis expressed sequence 10)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Testis Expressed 101 2     Testis-Expressed Sequence 10 Protein2
Testis Expressed Gene 101 2     SGRG5
Testis Expressed Sequence 101 2     TES101RP5
Ipi12     TEX1015
bA208F1.22     

External Ids:    HGNC: 259881   Entrez Gene: 548812   Ensembl: ENSG000001368917   OMIM: 6126655   UniProtKB: Q9NXF13   

Export aliases for TEX10 gene to outside databases

Previous GC identifers: GC09M098445 GC09M100143 GC09M102104 GC09M072663


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TEX10 Gene:
TEX10 (testis expressed 10) is a protein-coding gene. Diseases associated with TEX10 include brain cancer, and neuroblastoma.

UniProtKB/Swiss-Prot: TEX10_HUMAN, Q9NXF1
Function: Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is
recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of
ZNF148 target genes

Gene Wiki entry for TEX10 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000009.12  NC_018920.2  NT_008470.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the TEX10 gene promoter:
         HOXA3   CUTL1   POU3F2 (N-Oct-5b)   POU3F2 (N-Oct-5a)   LCR-F1   POU3F2   C/EBPalpha   Meis-1b   Meis-1a   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTEX10 promoter sequence
   Search Chromatin IP Primers for TEX10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TEX10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q31.1   Ensembl cytogenetic band:  9q31.1   HGNC cytogenetic band: 9q31.1

TEX10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TEX10 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M103064:  view genomic region     (about GC identifiers)

Start:
103,064,357 bp from pter      End:
103,115,259 bp from pter
Size:
50,903 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TEX10_HUMAN, Q9NXF1 (See protein sequence)
Recommended Name: Testis-expressed sequence 10 protein  
Size: 929 amino acids; 105674 Da
Subunit: Component of some MLL1/MLL complex, at least composed of the core components KMT2A/MLL1, ASH2L,
HCFC1/HCF1, WDR5 and RBBP5, as well as the facultative components BAP18, CHD8, E2F6, HSP70, INO80C, KANSL1,
LAS1L, MAX, MCRS1, MGA, KAT8/MOF, PELP1, PHF20, PRP31, RING2, RUVB1/TIP49A, RUVB2/TIP49B, SENP3, TAF1, TAF4,
TAF6, TAF7, TAF9 and TEX10. Component of the 5FMC complex, at least composed of PELP1, LAS1L, TEX10, WDR18 and
SENP3; the complex interacts with methylated CHTOP and ZNF148
Sequence caution: Sequence=CAI12537.1; Type=Erroneous gene model prediction; Sequence=CAI39742.1; Type=Erroneous
gene model prediction;
Secondary accessions: B4DYV2 Q5T722 Q5T723 Q8NCN8 Q8TDY0
Alternative splicing: 2 isoforms:  Q9NXF1-1   Q9NXF1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TEX10: NX_Q9NXF1

Explore proteomics data for TEX10 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys197
  • Modification sites at PhosphoSitePlus

  • See TEX10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001155056.1  NP_060216.2  

    ENSEMBL proteins: 
     ENSP00000364037   ENSP00000399872   ENSP00000444555   ENSP00000438120  

    TEX10 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for TEX10
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TEX10
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    Novus Biologicals TEX10 Protein
    Novus Biologicals TEX10 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TEX10

    TEX10 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    OriGene Custom Antibody Services for TEX10
    Novus Biologicals TEX10 Antibody
    Search for Antibodies for TEX10 at Abcam
    Cloud-Clone Corp. Antibodies for TEX10
    Search ThermoFisher Antibodies for TEX10
    LSBio Antibodies in human, mouse, rat for TEX10

    TEX10 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TEX10
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TEX10
    Cloud-Clone Corp. CLIAs for TEX10


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR011989 ARM-like
     IPR021133 HEAT_type_2
     IPR024679 IPI1/TEX10
     IPR016024 ARM-type_fold

    Graphical View of Domain Structure for InterPro Entry Q9NXF1

    ProtoNet protein and cluster: Q9NXF1

    1 Blocks protein domain: IPB000357 HEAT repeat

    UniProtKB/Swiss-Prot: TEX10_HUMAN, Q9NXF1
    Similarity: Contains 1 HEAT repeat


    TEX10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TEX10_HUMAN, Q9NXF1
    Function: Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is
    recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of
    ZNF148 target genes

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005488binding ----
    GO:0005515protein binding IPI--
         
    TEX10 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TEX10:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TEX10
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TEX10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TEX10
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TEX10

    miRNA
    Products:
        
    miRTarBase miRNAs that target TEX10:
    hsa-mir-92a-3p (MIRT049147), hsa-mir-222-3p (MIRT046576), hsa-mir-98-5p (MIRT027630)

    Block miRNA regulation of human, mouse, rat TEX10 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TEX10
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TEX10

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TEX10

    Clone
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    OriGene clones in human, mouse for TEX10 (see all 13)
    OriGene ORF clones in mouse, rat for TEX10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TEX10 (NM_017746)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TEX10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX10

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for TEX10 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TEX10_HUMAN, Q9NXF1: Nucleus, nucleoplasm (By similarity). Cytoplasm (By similarity). Nucleus membrane;
    Multi-pass membrane protein. Nucleus, nucleolus. Note=Mainly found in the nucleoplasm, with low levels detected
    in the cytoplasmic and chromatin fractions (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    plasma membrane3
    cytosol2

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IEA--
    GO:0005737cytoplasm IEA--
    GO:0016021integral component of membrane IEA--
    GO:0031965nuclear membrane IEA--
    GO:0071339MLL1 complex IDA15960975

    TEX10 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TEX10
    Interactions:

        Search GeneGlobe Interaction Network for TEX10

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TEX10 (Q9NXF11, 2, 3 ENSP000003640374) via UniProtKB, MINT, STRING, and/or I2D (see all 185)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SENP3Q9H4L41, 2, 3, ENSP000003140294EBI-2371062,EBI-2880236 MINT-8151574 MINT-8151622 I2D: score=1 STRING: ENSP00000314029
    WDR18Q9BV382, 3, ENSP000002512894MINT-8150073 MINT-8149992 MINT-8150055 MINT-8151622 MINT-6488791 I2D: score=1 STRING: ENSP00000251289
    PTPN12Q052092, 3MINT-61771 I2D: score=3 
    PELP1Q8IZL82, 3, ENSP000003013964MINT-8150073 MINT-8150055 MINT-8149978 MINT-8151622 MINT-6488791 I2D: score=1 STRING: ENSP00000301396
    LAS1LQ9Y4W22, ENSP000003639444MINT-8151622 MINT-6488791 STRING: ENSP00000363944
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TEX10



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TEX10 gene (2 alternative transcripts): 
    NM_001161584.1  NM_017746.3  

    Unigene Cluster for TEX10:

    Testis expressed 10
    Hs.494648  [show with all ESTs]
    Unigene Representative Sequence: NM_017746
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000374902(uc011lvf.2 uc004bas.3) ENST00000477648 ENST00000429235
    ENST00000535814(uc011lvg.2) ENST00000537512(uc011lvh.1)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TEX10 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TEX10
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for TEX10
    Predesigned siRNA for gene silencing in human, mouse, rat TEX10
    Clone
    Products:
         
    OriGene clones in human, mouse for TEX10 (see all 13)
    OriGene ORF clones in mouse, rat for TEX10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TEX10 (NM_017746)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TEX10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEX10
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TEX10
    OriGene qSTAR qPCR primer pairs in human, mouse for TEX10
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TEX10
      QuantiTect SYBR Green Assays in human, mouse, rat TEX10
      QuantiFast Probe-based Assays in human, mouse, rat TEX10

    Additional mRNA sequence: 

    AB060968.1 AJ420436.1 AK000294.1 AK055719.1 AK298916.1 AK302619.1 AY598337.1 BC030652.2 

    12 DOTS entries:

    DT.449369  DT.100838042  DT.121159816  DT.100783364  DT.115451  DT.40133115  DT.91750849  DT.99971373 
    DT.95168444  DT.97772028  DT.91750846  DT.91750853 

    Selected AceView cDNA sequences (see all 200):

    AA233499 AA447126 CD642405 AA344742 AI374653 Z46082 BF795563 BM988665 
    AA173535 AA442625 AA233459 AW593024 AW440271 BQ017038 BM824688 BG285243 
    AI288689 CA312967 T34973 AW575752 BP375850 CA419187 CB136072 AI569471 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TEX10    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15
    SP1:                                                                                      -                           
    SP2:                                      -     -                                                                     
    SP3:                    -                                                                                             
    SP4:                                                                                                                  


    ECgene alternative splicing isoforms for TEX10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TEX10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CACCCCTCAG
    TEX10 Expression
    About this image

    TEX10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TEX10 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.494648
        Custom PCR Arrays for TEX10
    Primer
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    QuantiFast Probe-based Assays in human, mouse, rat TEX10
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEX10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TEX10 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tex101 , 5 testis expressed gene 101, 5 88.93(n)1
    88.78(a)1
      4 (26.13 cM)5
    2695361  NM_172304.31  NP_758508.21 
     484308585 
    chicken
    (Gallus gallus)
    Aves TEX101 testis expressed 10 73.05(n)
    73.24(a)
      420993  NM_001031008.2  NP_001026179.1 
    lizard
    (Anolis carolinensis)
    Reptilia TEX106
    testis expressed 10
    65(a)
    1 ↔ 1
    6(54968388-55022018)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.63812 Transcribed sequence with weak similarity to protein more 77.45(n)    BX714021.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.101722 Danio rerio mRNA similar to hypothetical protein FLJ2 more 71.75(n)    BC044417.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG15756
    --
    26(a)
    1 ↔ 1
    X(8011096-8013166)


    ENSEMBL Gene Tree for TEX10 (if available)
    TreeFam Gene Tree for TEX10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TEX10 (see all 987)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1404264981,2
    --103063954(+) TAAAC-/AGTGAT 2 -- int10--------
    rs1826678581,2
    --103063986(+) TGGGGA/GTTGCT 2 -- int10--------
    rs1862479211,2
    --103063991(+) GTTGCG/TTTCAT 2 -- int10--------
    rs1449788301,2
    C--103064034(+) GTAAG-/AGAT  
            
    AGATA
    2 -- int10--------
    rs1905679991,2
    --103064035(+) GTAAGA/CGATAG 2 -- int10--------
    rs120038111,2
    C,F,H--103064060(+) AAGTGT/CTCACT 2 -- int111Minor allele frequency- C:0.05NS EA NA WA CSA 546
    rs1839975441,2
    --103064120(+) GATCAC/TAAAAA 2 -- int10--------
    rs1390715571,2
    --103064125(+) CAAAAA/TCACAA 2 -- int10--------
    rs109890491,2
    C,F,A,H--103064153(+) GATGGG/AATTAC 2 -- int128Minor allele frequency- A:0.28NS EA NA WA CSA 2770
    rs356896591,2
    C--103064335(+) TCATA-/TTATCA 2 -- int10--------

    HapMap Linkage Disequilibrium report for TEX10 (103064357 - 103115259 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TEX10:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv507523CNV Insertion20534489
    nsv893623CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TEX10
    DNA2.0 Custom Variant and Variant Library Synthesis for TEX10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 612665    OMIM disorders: --

    5 diseases for TEX10:    
    About MalaCards
    brain cancer    neuroblastoma    lung cancer    squamous cell carcinoma
    malaria


    TEX10 for disorders           About GeneDecksing


    Export disorders for TEX10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TEX10 gene, integrated from 10 sources (see all 31):
    (articles sorted by number of sources associating them with TEX10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF. (PubMed id 15960975)1, 2 Dou Y.... Roeder R.G. (Cell 2005)
    2. Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer. (PubMed id 15334068)1, 2 Petroziello J.... Carter P. (Oncogene 2004)
    3. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (Nature 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. Neuroblastoma oligo-capping cDNA project: toward the understanding of the genesis and biology of neuroblastoma. (PubMed id 12880961)1, 2 Ohira M.... Nakagawara A. (Cancer Lett. 2003)
    7. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (Mol. Biol. Cell 2002)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. (PubMed id 23667531)1 Cox J.L....Rizzino A. (PLoS ONE 2013)
    10. LAS1L interacts with the mammalian Rix1 complex to regulate ribosome biogenesis. (PubMed id 22190735)1 Castle C.D....Denicourt C. (Mol. Biol. Cell 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 54881 HGNC: 25988 AceView: TEX10 Ensembl:ENSG00000136891 euGenes: HUgn54881
    ECgene: TEX10 H-InvDB: TEX10

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TEX10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TEX10 gene:
    Search GeneIP for patents involving TEX10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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