TET1 Gene
protein-coding GIFtS : 48 GCID: GC10 P070320
tet methylcytosine dioxygenase 1 CXXC zinc finger 6, tet oncogene 1 )CXXC6 )
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Aliasesfor TET1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Tet Methylcytosine Dioxygenase 1 1 2 Leukemia-Associated Protein With A CXXC Domain2 3 CXXC61 2 3 5 Ten-Eleven Translocation 1 Gene Protein2 3 LCX1 2 3 5 CXXC-Type Zinc Finger Protein 62 3 KIAA16761 3 5 EC 1.14.11.N21 BA119F7.11 CXXC Finger 62 CXXC Zinc Finger 61 2 Methylcytosine Dioxygenase TET12 Tet Oncogene 11 2 Ten-Eleven Translocation-12
Export aliases for TET1 gene to outside databases Previous GC identifers: GC10P069991 GC10P064321
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Summariesfor TET1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: TET1_HUMAN, Q8NFU7 Function : Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into5-hydroxymethylcytosine (5hmC). Might initiate a process leading to cytosine demethylation through deamination into 5-hydroxymethyluracil (5hmU) and subsequent replacement by unmethylated cytosine by the base excision repair system. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. Preferentially binds to CpG-rich sequences at promoters of both transcriptionally active and polycomb-repressed genes. By controlling the levels of 5mC and 5hmC at gene promoters, it may regulate the gene expression silencing induced by cytosine methylation. May have a dual function by also repressing the expression of a subset of genes through recruitment of transcriptional repressors to promoters. Involved in the balance between pluripotency and lineage commitment of cells it plays a role in embryonic stem cells maintenance and inner cell mass cell specification
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Genomic Viewsfor TET1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000010.10 NC_018921.1 NT_030059.13 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the TET1 gene promoter:STAT1 RREB-1 Pax-6 STAT1beta FOXO3 STAT1alpha FOXO3b MZF-1 FOXO3a ATF6 Other transcription factors Search SABiosciences Chromatin IP Primers for TET1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TET1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 10q21 Ensembl cytogenetic band: 10q21.3 HGNC cytogenetic band: 10q21 TET1 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 10 GeneLoc Exon Structure
GeneLoc location for GC10P070320: view genomic region
(about GC identifiers )
Start: 70,320,117 bp from pter End:
70,454,239 bp from pter
Size: 134,123 bases Orientation:
plus strand
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Proteinsfor TET1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: TET1_HUMAN, Q8NFU7 See
protein sequence )Recommended Name: Size : 2136 amino acids; 235309 DaCofactor : Binds 1 Fe(2+) ion per subunitSubunit : Interacts with SIN3A; recruits the transcriptional co-repressor SIN3A to gene promotersSubcellular location : Nucleus (Probable)Sequence caution : Sequence=CAD28467.3; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence;
Secondary accessions : Q5VUP7 Q7Z6B6 Q8TCR1 Q9C0I7Explore the universe of human proteins at neXtProt for TET1: NX_Q8NFU7 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q8NFU7 4 DME Specific Peptides for TET1 (Q8NFU7 ) TET1 Protein expression data from MOPED and PaxDb : About this image REFSEQ proteins: NP_085128.2 ENSEMBL proteins: ENSP00000362748 Human Recombinant Protein Products for TET1: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
About GeneDecksing TET1 Antibody Products: Assay Products for TET1:
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Protein
Domains /for TET1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 2 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q8NFU7 ProtoNet protein and cluster: Q8NFU7
UniProtKB/Swiss-Prot: TET1_HUMAN, Q8NFU7 Similarity : Belongs to the TET familySimilarity : Contains 1 CXXC-type zinc finger
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Functionfor TET1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Molecular Function: UniProtKB/Swiss-Prot Summary: TET1_HUMAN, Q8NFU7 Function : Dioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into5-hydroxymethylcytosine (5hmC). Might initiate a process leading to cytosine demethylation through deamination into 5-hydroxymethyluracil (5hmU) and subsequent replacement by unmethylated cytosine by the base excision repair system. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. Preferentially binds to CpG-rich sequences at promoters of both transcriptionally active and polycomb-repressed genes. By controlling the levels of 5mC and 5hmC at gene promoters, it may regulate the gene expression silencing induced by cytosine methylation. May have a dual function by also repressing the expression of a subset of genes through recruitment of transcriptional repressors to promoters. Involved in the balance between pluripotency and lineage commitment of cells it plays a role in embryonic stem cells maintenance and inner cell mass cell specification Catalytic activity : DNA 5-methylcytosine + 2-oxoglutarate + O(2) = DNA 5-hydroxymethylcytosine + succinate + CO(2) Enzyme Number (IUBMB): EC 1.14.11.n2 1 2
Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005506 iron ion binding
IDA 19372391 GO:0008270 zinc ion binding
IEA -- GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
IEA -- GO:0043566 structure-specific DNA binding
IDA 19372391 GO:0070579 methylcytosine dioxygenase activity
IMP --
About GeneDecksing Phenotypes: 2 GenomeRNAi human phenotypes for TET1 :5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tet1) :About GeneDecksing Animal Models: Tet1 tm1.1Jae for TET1Clone Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 2 )human mouse rat OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: TET1 (NM_030625 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TET1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse rat TET1
In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TET1
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Pathways & Interactionsfor TET1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TET1 STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)1 Interacting protein for TET1 (ENSP00000362748 4 via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7 ): About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0001826 inner cell mass cell differentiation
ISS -- GO:0006351 transcription, DNA-dependent
IEA -- GO:0016568 chromatin modification
IEA -- GO:0019827 stem cell maintenance
ISS -- GO:0044030 regulation of DNA methylation
IEA --
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Drugs & Compoundsfor TET1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for TET1 TET1
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Transcriptsfor TET1 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for TET1 gene: NM_030625.2 Unigene Cluster for TET1:
Tet methylcytosine dioxygenase 1 Hs.567594 [show with all ESTs ] Unigene Representative Sequence: NM_030625 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000373644 (uc001jok.4 uc009xpw.1 ) Clone OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat see all 2 )human mouse rat OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: TET1 (NM_030625 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TET1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse rat TET1
Additional cDNA sequence: AB051463.1 AF430147.1 AK123436.1 AL832334.1 AL832337.1 BC053905.1 FM165197.1
4 DOTS entries : DT.432626 DT.101972582
DT.91951770 DT.121238941 24/52 AceView cDNA sequences (see all 52 ):
AF430147 CA412990 AW025923 AK123436 AI652906 BX955006 AI741535 W93385 AL713658 W94969 AB051463 NM_030625 AI637887 AL832337 AW339808 BE463873 BX103926 AI625029 BM698070 BC053905 CD652797 BP871022 CD643453 C05315 GeneLoc Exon Structure
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Expression for TET1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section TET1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: -- About this image TET1 expression in embryonic tissues and stem cells About this table
Stem Cell Differentiation: 2 LifeMap Cells Name Category Line H9 (WA09) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass Sox17-GFP genetically modified stem cells (Embryonic Stem Cell)Early Embryo, Inner Cell Mass Expression: Experimental details:
In-situ hybridization
See TET1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TET1 SOURCE GeneReport for Unigene cluster: Hs.567594 UniProtKB/Swiss-Prot: TET1_HUMAN, Q8NFU7 Tissue specificity : Expressed in fetal heart, lung and brain, and in adult skeletal muscle, thymus and ovary. Notdetected in adult heart, lung or brain SABiosciences Custom PCR Arrays for TET1 Primer OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TET1
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Orthologsfor TET1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for TET1 gene from 5/16 species (see all 16 ) About this table
ENSEMBL Gene Tree for TET1 (if available)TreeFam Gene Tree for TET1 (if available)
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Paralogsfor TET1 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for TET1 gene TET2 2 TET3 2 1 SIMAP similar gene for TET1 using alignment to 1 protein entry: TET1_HUMAN :CXXC4 About GeneDecksing 1 Pseudogenes.org Pseudogene for TET1 PGOHUM00000248454
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Genomic Variantsfor TET1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical Chr 10 pos Sequence # AA Type More # Allele Pop Total More
HapMap Linkage Disequilibrium report for TET1 (70320117 - 70454239 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for TET1: -- Human Gene Mutation Database (HGMD) : TET1 SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human mouse rat
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Disorders
/ Diseasesfor TET1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section About GeneDecksing OMIM gene information: 607790
OMIM disorders : --UniProtKB/Swiss-Prot: TET1_HUMAN, Q8NFU7 Note=A chromosomal aberration involving TET1 may be a cause of acute leukemias. Translocation t(10;11)(q22;q23) with MLL. This is a rare chromosomal translocation 5' MLL-TET1 3' 8 : About MalaCards leukemia acute myeloid leukemia myeloid leukemia myeloid malignancy hematopoiesis alzheimer's disease tuberculosis neuronitis Human Genome Epidemiology (HuGE) Navigator: TET1 (3 documents) Export disorders for TET1 gene to outside databases
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Publicationsfor TET1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for TET1 gene, integrated from 9 sources (see all 21 ):(articles sorted by number of sources associating them with TET1) Utopia : connect your pdf to the dynamic
TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23). (PubMed id 12646957) 1 , 2 , 3(2003) LCX, leukemia-associated protein with a CXXC domain, is fused to MLL in acute myeloid leukemia with trilineage dysplasia having t(10;11)(q22;q23). (PubMed id 12124344) 1 , 2 , 3(2002) Hydroxylation of 5-methylcytosine by TET1 promotes ac tive DNA demethylation in the adult brain. (PubMed id 21496894) 1 , 2 (2011) Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by the MLL fusion partner TET1. (PubMed id 19372391) 1 , 2 (2009) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 1 , 2 (2004) The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054) 1 , 2 (2004) Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11214970) 1 , 2 (2000) Loss of 5-hydroxymethylcytosine is accompanied with ma lignant cellular transformation. (PubMed id 22320381) 1 (2012) Nuclear exclusion of TET1 is associated with loss of 5 -hydroxymethylcytosine in IDH1 wild-type gliomas. (PubMed id 22688054) 1 (2012) Oncometabolite 2-hydroxyglutarate is a competitive in hibitor of I+-ketoglutarate-dependent dioxygenases. (PubMed id 21251613) 1 (2011)
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External Searches for TET1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing TET1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing TET1 gene
(According to HUGE )
About This Section
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Specialized Databases showing TET1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for TET1 Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for TET1 gene: TET1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TET1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
OriGene Antibodies for TET1 OriGene shRNA RFP for TET1 OriGene 29mer shRNA kits in GFP-retroviral vector in human mouse rat OriGene genome-wide validated SYBR primer pairs in human mouse rat Browse OriGene Protein Over-expression Lysates Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for TET1 OriGene 3'-UTR Clone for TET1 OriGene untagged cDNA clones in CMV expression vector in human mouse rat OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human mouse rat Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for TET1 OriGene Custom Protein Services for TET1 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TET1 QIAGEN SeqTarget long-range PCR primers in human mouse rat QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TET1 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human mouse rat QIAGEN QuantiFast Probe-based Assays in human mouse rat QIAGEN QuantiTect SYBR Green Assays in human mouse rat
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TET1 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TET1
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Vector BioLabs ready-to-use adenovirus/AAV for human , mouse rat TET1
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Aliases for TET1
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Disorders / Diseases for TET1
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Expression for TET1
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Genomic Views for TET1
Intellectual Property for TET1
Orthologs for TET1
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Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine 
Negative
Selective marker
Curated
In-situ hybridization
