Aliases for TESPA1 Gene
External Ids for TESPA1 Gene
Previous Symbols for TESPA1 Gene
GeneCards Summary for TESPA1 Gene
TESPA1 (Thymocyte Expressed, Positive Selection Associated 1) is a Protein Coding gene. An important paralog of this gene is SSFA2.
UniProtKB/Swiss-Prot for TESPA1 Gene
Required for the development and maturation of T-cells, its function being essential for the late stages of thymocyte development (By similarity). Plays a role in T-cell antigen receptor (TCR)-mediated activation of the ERK and NFAT signaling pathways, possibly by serving as a scaffolding protein that promotes the assembly of the LAT signalosome in thymocytes. May play a role in the regulation of inositol 1,4,5-trisphosphate receptor-mediated Ca(2+) release and mitochondrial Ca(2+) uptake via the mitochondria-associated endoplasmic reticulum membrane (MAM) compartment.