TERF2IP Gene
protein-coding GIFtS: 54
GCID: GC16P075681
|
|
telomeric repeat binding factor 2, interacting protein
| |
Aliases
for TERF2IP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Telomeric Repeat Binding Factor 2, Interacting Protein1 2 | | RAP1 Homolog2 3 | | RAP11 2 3 5 | | TERF2-Interacting Telomeric Protein 12 3 | | Dopamine Receptor-Interacting Protein 52 3 | | TRF2-Interacting Telomeric Protein 12 3 | | Repressor/Activator Protein 1 Homolog2 3 | | Dopamine Receptor Interacting Protein 52 | | DRIP52 3 | | Telomeric Repeat-Binding Factor 2-Interacting Protein 12 | | HRap11 | | TRF2-Interacting Telomeric RAP1 Protein2 |
Export aliases for TERF2IP gene to outside databasesPrevious GC identifers: GC16P066611 GC16P076642 GC16P075420 GC16P075461 GC16P074239 GC16P061435 |
Summaries
for TERF2IP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TERF2IP:
The gene encodes a protein that is part of a complex involved in telomere length regulation. Pseudogenes are present onchromosomes 5 and 22. (provided by RefSeq, Apr 2010)
UniProtKB/Swiss-Prot: TE2IP_HUMAN, Q9NYB0Function: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation oftelomere length and protection as a component of the shelterin complex (telosome). In contrast to other components ofthe shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeresagainst non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomererecombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length. Doesnot bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with TERF2.Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric5'-TTAGGG-3' sites via its association with TERF2 or other factors, and regulates gene expression. When cytoplasmic,associates with the I-kappa-B-kinase (IKK) complex and acts as a regulator of the NF-kappa-B signaling by promotingIKK-mediated phosphorylation of RELA/p65, leading to activate expression of NF-kappa-B target genes
Gene Wiki entry for TERF2IP
|
Genomic Views
for TERF2IP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TERF2IP gene promoter:
HOXA9 HOXA9B Pax-5 Lmo2 Tal-1beta Egr-4 E47 Meis-1b Meis-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for TERF2IP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TERF2IP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q23.1 Ensembl cytogenetic band: 16q23.1 HGNC cytogenetic band: 16q23.1TERF2IP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P075681: view genomic region
(about GC identifiers)
Start:
|
75,681,635 bp from pter |
End:
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75,795,051 bp from pter |
Size:
|
113,417 bases |
Orientation:
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plus strand |
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Proteins
for TERF2IP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TE2IP_HUMAN, Q9NYB0 (See
protein sequence)Recommended Name: Telomeric repeat-binding factor 2-interacting protein 1 Size: 399 amino acids; 44260 Da
Subunit: Associates with the I-kappa-B-kinase (IKK) core complex, composed of CHUK, IKBKB and IKBKG (By similarity).Homodimer. Component of the shelterin complex (telosome) composed of TERF1, TERF2, TINF2, TERF2IP ACD and POT1.Interacts with TERF2; the interaction is direct. Does not interact with TERF1. Interacts with SLX4/BTBD12
Subcellular location: Nucleus. Cytoplasm (By similarity). Chromosome. Chromosome, telomere. Note=Associates withchromosomes, both at telomeres and in extratelomeric sites. Also exists as a cytoplasmic form, where it associateswith the IKK complex (By similarity)
Miscellaneous: Shares a bidirectional promoter with KARS (PubMed:14659874)
Caution: Was reported to participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediatedrepair in the absence of TERF2 (PubMed:19763083). However, this probably does not corresponds to its primary functionand experiments in mouse showed that it is dispensible for such process and is required for repressiion ofhomology-directed repair (HDR)
Sequence caution: Sequence=AAL55783.1; Type=Frameshift; Positions=151; Sequence=BAA91317.1; Type=Erroneous termination;Positions=299; Note=Translated as Glu; Sequence=BAG60996.1; Type=Erroneous initiation; Note=Translation N-terminallyextended;
2 PDB 3D structures from  and Proteopedia  for TERF2IP:1FEX (3D)
3K6G (3D)
Secondary accessions: B4DQN4 Q4W4Y2 Q8WYZ3 Q9NWR2Explore the universe of human proteins at neXtProt for TERF2IP: NX_Q9NYB0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NYB0
TERF2IP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_061848.2
ENSEMBL proteins: ENSP00000300086 ENSP00000454399 ENSP00000456092 Reactome Protein details: Q9NYB0
Human Recombinant Protein Products for TERF2IP:
Gene Ontology (GO): 5/8 cellular component terms (GO ID links to tree view) (see all 8): About this table
TERF2IP for ontologies About GeneDecksing
TERF2IP Antibody Products:
Assay Products for TERF2IP: |
Protein
Domains /
Families
for TERF2IP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TERF2IP for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NYB0ProtoNet protein and cluster: Q9NYB0 1 Blocks protein family: IPB001357 BRCT domain
UniProtKB/Swiss-Prot: TE2IP_HUMAN, Q9NYB0Similarity: Belongs to the RAP1 familySimilarity: Contains 1 BRCT domainSimilarity: Contains 1 Myb-like domain |
Function
for TERF2IP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: TE2IP_HUMAN, Q9NYB0Function: Acts both as a regulator of telomere function and as a transcription regulator. Involved in the regulation oftelomere length and protection as a component of the shelterin complex (telosome). In contrast to other components ofthe shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeresagainst non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomererecombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length. Doesnot bind DNA directly: recruited to telomeric double-stranded 5'-TTAGGG-3' repeats via its interaction with TERF2.Independently of its function in telomeres, also acts as a transcription regulator: recruited to extratelomeric5'-TTAGGG-3' sites via its association with TERF2 or other factors, and regulates gene expression. When cytoplasmic,associates with the I-kappa-B-kinase (IKK) complex and acts as a regulator of the NF-kappa-B signaling by promotingIKK-mediated phosphorylation of RELA/p65, leading to activate expression of NF-kappa-B target genes Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
TERF2IP for ontologies About GeneDecksing
Phenotypes:
7 MGI mutant phenotypes (inferred from 4 alleles ) (MGI details for Terf2ip):
TERF2IP for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Terf2iptm1.2Tdl for TERF2IP
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TERF2IP (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TERF2IP
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TERF2IP (NM_018975) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TERF2IP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TERF2IP |
|
Pathways & Interactions
for TERF2IP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Meiotic Synapsis | | | 2 | DNA Damage | | | 3 | Cell Cycle / Checkpoint Control | | | 4 | Cell Cycle | | | 5 | Telomere Extension by Telomerase | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for TERF2IP
3 
Cell Signaling Technology (CST) Pathways for TERF2IP
2  BioSystems Pathways for TERF2IP
5/7 
Reactome Pathways for TERF2IP (see all 7)
TERF2IP for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TERF2IP
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/167 Interacting proteins for TERF2IP (Q9NYB01, 2, 3 ENSP000003000864) via UniProtKB, MINT, STRING, and/or I2D (see all 167)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| TERF2 | Q155541, 2, 3, ENSP000002549424 | EBI-750109,EBI-706637 MINT-8286662 MINT-8286652 I2D:
score=6 STRING: ENSP00000254942 | | AP2B1 | P630102, 3, ENSP000003144144 | MINT-67704 I2D:
score=5 STRING: ENSP00000314414 | | ORC2 | Q134162, 3, ENSP000002342964 | MINT-2831429 I2D:
score=1 STRING: ENSP00000234296 | | SLX4 | Q8IY921, 3, ENSP000002940084 | EBI-750109,EBI-2560942 I2D:
score=2 STRING: ENSP00000294008 | | HSPA1A | P081073 | I2D:
score=3 |
About this table
Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000723 | telomere maintenance |
TAS | -- | | GO:0006351 | transcription, DNA-dependent |
IEA | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
ISS | -- | | GO:0007004 | telomere maintenance via telomerase |
TAS | 10850490 | | GO:0010569 | regulation of double-strand break repair via homologous recombination |
ISS | -- |
TERF2IP for ontologies About GeneDecksing
|
Drugs & Compounds
for TERF2IP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TERF2IP for compounds About GeneDecksing
 Browse Tocris compounds for TERF2IP
1 Novoseek chemical compound relationship for TERF2IP gene About this table
Search CenterWatch for drugs/clinical trials and news about TERF2IP / TE2IP
|
Transcripts
for TERF2IP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TERF2IP gene: NM_018975.3 Unigene Cluster for TERF2IP: Telomeric repeat binding factor 2, interacting protein Hs.301419 [show with all ESTs]Unigene Representative Sequence: NM_0189753 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000300086(uc002fet.2) ENST00000569234 ENST00000564671
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TERF2IP (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TERF2IP
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TERF2IP (NM_018975) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TERF2IP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TERF2IP |
Additional cDNA sequence: AF250393.1 AF262988.1 AF289599.1 AK298535.1 AK298880.1 AK307901.1 BC004465.1 BC005841.2 BC016739.1 BC022428.1 BC078171.1 24/27 DOTS entries (see all 27): DT.119914 DT.100764395 DT.455827 DT.100654768 DT.100887098 DT.100699573 DT.100887099 DT.92449074 DT.99975006 DT.120666393 DT.120666414 DT.95264203 DT.120666466 DT.120666444 DT.100662279 DT.100676787 DT.100836385 DT.100887097 DT.100887108 DT.100887112 DT.120666356 DT.95286125 DT.97859746 DT.100649696 24/467 AceView cDNA sequences (see all 467): BE858388 AA426157 AA399316 CR626430 BX108635 CB215825 BE858899 AW044227 AW088251 AA361398 AA382948 AA758367 AJ707088 BQ649773 AL535048 AA769291 AA663668 AA349406 AW028907 CB157489 AW163647 R17363 CD251204 BE855776
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for TERF2IP About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 |
|---|
|
| SP1: | | | | | - | | | | | | |
| SP2: | | | | | | | | | | |
ECgene alternative splicing isoforms for TERF2IP
|
Expression
for TERF2IP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TERF2IP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTAGGTGAGG
About this image
See TERF2IP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TERF2IP
SOURCE GeneReport for Unigene cluster: Hs.301419
UniProtKB/Swiss-Prot: TE2IP_HUMAN, Q9NYB0Tissue specificity: Ubiquitous. Highly expressed
SABiosciences Expression via Pathway-Focused PCR Arrays including TERF2IP:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TERF2IP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TERF2IP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TERF2IP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TERF2IP |
Orthologs
for TERF2IP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for TERF2IP gene from 4/13 species (see all 13) About this table
ENSEMBL Gene Tree for TERF2IP (if available)
TreeFam Gene Tree for TERF2IP (if available) |
Paralogs
for TERF2IP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TERF2IP gene
TERF2IP for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for TERF2IP
PGOHUM00000246392 PGOHUM00000235487
|
Genomic Variants
for TERF2IP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TERF2IP (75681635 - 75795051 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TERF2IP: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TERF2IP |
|
Disorders
/ Diseases
for TERF2IP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TERF2IP for disorders About GeneDecksing
OMIM gene information: 605061
OMIM disorders: --
20/23  diseases for TERF2IP (see all 23): About MalaCardsovarian sex cord tumors dyskeratosis congenita babesiosis tuberous sclerosis
chronic lymphocytic leukemia dyskeratosis lymphocytic leukemia ulcerative colitis
cerebrovascular disease crohn's disease colon carcinoma pancreatic carcinoma
gastric cancer leukemia osteosarcoma lung cancer
breast cancer pancreatitis carcinoma cholesterol
2 Novoseek disease relationships for TERF2IP gene About this table
Human Genome Epidemiology (HuGE) Navigator: TERF2IP (5 documents)
Export disorders for TERF2IP gene to outside databases
|
Publications
for TERF2IP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TERF2IP gene, integrated from 9 sources (see all 117):
(articles sorted by number of sources associating them with TERF2IP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Identification of human RAP1: implications for telomere evolution. (PubMed id 10850490)1, 2, 3, 9 Li B.... de Lange T. (2000)
- NMR structure of the hRap1 Myb motif reveals a canonical three-helix bundle lacking the positive surface charge typical of Myb DNA-binding domains. (PubMed id 11545594)1, 2, 9 Hanaoka S....Nishimura Y. (2001)
- Shelterin: the protein complex that shapes and safeguards human telomeres. (PubMed id 16166375)1, 2, 9 de Lange T. (2005)
- Telosome, a mammalian telomere-associated complex formed by multiple telomeric proteins. (PubMed id 15383534)1, 2, 9 Liu D.... Songyang Z. (2004)
- TIN2 binds TRF1 and TRF2 simultaneously and stabilizes the TRF2 complex on telomeres. (PubMed id 15316005)1, 2, 9 Ye J.Z.-S.... de Lange T. (2004)
- Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair. (PubMed id 19596235)1, 2 Svendsen J.M.... Harper J.W. (2009)
- A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (2006)
- Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)1, 2 Wan D....Gu J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
|
External Searches for TERF2IP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TERF2IP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TERF2IP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TERF2IP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for TERF2IP gene:
Search GeneIP for patents involving TERF2IP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TERF2IP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
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| | |  | OriGene Antibodies for TERF2IP | | OriGene shRNA RFP for TERF2IP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TERF2IP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TERF2IP | | | OriGene Protein Over-expression Lysate for TERF2IP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TERF2IP | | OriGene 3'-UTR Clone for TERF2IP | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TERF2IP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TERF2IP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TERF2IP | | OriGene Custom Protein Services for TERF2IP | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TERF2IP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TERF2IP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TERF2IP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TERF2IP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TERF2IP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TERF2IP |
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| | | | Search Tocris compounds for TERF2IP |
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 | | | TERF2IP Proteins, Antibodies, CLIAs, and ELISAs |
| | | |  |  |  |  | | | | ThermoFisher Antibodies for TERF2IP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TERF2IP |
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