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Aliases for TEPP Gene

Aliases for TEPP Gene

  • Testis, Prostate And Placenta Expressed 2 3 5

External Ids for TEPP Gene

Previous GeneCards Identifiers for TEPP Gene

  • GC16P057785
  • GC16P056567
  • GC16P058010
  • GC16P043877

Summaries for TEPP Gene

GeneCards Summary for TEPP Gene

TEPP (Testis, Prostate And Placenta Expressed) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEPP Gene

Genomics for TEPP Gene

Regulatory Elements for TEPP Gene

Genomic Location for TEPP Gene

Chromosome:
16
Start:
57,976,435 bp from pter
End:
57,988,354 bp from pter
Size:
11,920 bases
Orientation:
Plus strand

Genomic View for TEPP Gene

Genes around TEPP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEPP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEPP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEPP Gene

Proteins for TEPP Gene

  • Protein details for TEPP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q6URK8-TEPP_HUMAN
    Recommended name:
    Testis, prostate and placenta-expressed protein
    Protein Accession:
    Q6URK8
    Secondary Accessions:
    • Q6URK7

    Protein attributes for TEPP Gene

    Size:
    271 amino acids
    Molecular mass:
    30717 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TEPP Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TEPP Gene

Proteomics data for TEPP Gene at MOPED

Post-translational modifications for TEPP Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEPP Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEPP Gene

Domains & Families for TEPP Gene

Protein Domains for TEPP Gene

ProtoNet:

Suggested Antigen Peptide Sequences for TEPP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEPP: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TEPP Gene

Function for TEPP Gene

Phenotypes for TEPP Gene

GenomeRNAi human phenotypes for TEPP:
genes like me logo Genes that share phenotypes with TEPP: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TEPP Gene

Localization for TEPP Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEPP Gene

Secreted.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TEPP Gene COMPARTMENTS Subcellular localization image for TEPP gene
Compartment Confidence
extracellular 4
lysosome 1
plasma membrane 1
vacuole 1

No data available for Gene Ontology (GO) - Cellular Components for TEPP Gene

Pathways & Interactions for TEPP Gene

SuperPathways for TEPP Gene

No Data Available

Interacting Proteins for TEPP Gene

Gene Ontology (GO) - Biological Process for TEPP Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEPP Gene

Drugs & Compounds for TEPP Gene

No Compound Related Data Available

Transcripts for TEPP Gene

mRNA/cDNA for TEPP Gene

Unigene Clusters for TEPP Gene

Testis, prostate and placenta expressed:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TEPP Gene

ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7
SP1:
SP2: -
SP3: - -

Relevant External Links for TEPP Gene

GeneLoc Exon Structure for
TEPP
ECgene alternative splicing isoforms for
TEPP

Expression for TEPP Gene

mRNA expression in normal human tissues for TEPP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for TEPP Gene

This gene is overexpressed in Testis (x21.6) and Thyroid (x4.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TEPP Gene



SOURCE GeneReport for Unigene cluster for TEPP Gene Hs.132976

mRNA Expression by UniProt/SwissProt for TEPP Gene

Q6URK8-TEPP_HUMAN
Tissue specificity: Expressed in testis, prostate and placenta.
genes like me logo Genes that share expression patterns with TEPP: view

Protein tissue co-expression partners for TEPP Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for Protein differential expression in normal tissues for TEPP Gene

Orthologs for TEPP Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEPP Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TEPP 35
  • 87.35 (n)
  • 87.5 (a)
TEPP 36
  • 88 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TEPP 35
  • 86.57 (n)
  • 82.87 (a)
TEPP 36
  • 73 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Tepp 35
  • 81.79 (n)
  • 79.17 (a)
Tepp 16
Tepp 36
  • 79 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia TEPP 35
  • 96.98 (n)
  • 95.97 (a)
TEPP 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tepp 35
  • 80.86 (n)
  • 75.46 (a)
oppossum
(Monodelphis domestica)
Mammalia TEPP 36
  • 67 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TEPP 36
  • 56 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tepp 35
  • 52.79 (n)
  • 45.41 (a)
Species with no ortholog for TEPP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEPP Gene

ENSEMBL:
Gene Tree for TEPP (if available)
TreeFam:
Gene Tree for TEPP (if available)

Paralogs for TEPP Gene

No data available for Paralogs for TEPP Gene

Variants for TEPP Gene

Sequence variations from dbSNP and Humsavar for TEPP Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs9934227 - 57,985,492(+) CCTCA(A/G)CCAGA reference, synonymous-codon, missense
rs2241771 -- 57,987,491(+) CAGAC(A/C)GAGGA reference, synonymous-codon, utr-variant-3-prime
rs2241772 -- 57,987,780(+) GCTCC(A/G)GCCCC utr-variant-3-prime
rs2304485 -- 57,985,166(+) TGGGG(A/C/G/T)GGGGC intron-variant
rs2304486 -- 57,985,349(+) TGAGG(C/G)GGGAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TEPP Gene

Variant ID Type Subtype PubMed ID
dgv2875n71 CNV Loss 21882294
nsv523659 CNV Loss 19592680
nsv1816 CNV Loss 18451855

Variation tolerance for TEPP Gene

Residual Variation Intolerance Score: 45.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.17; 23.59% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEPP Gene

HapMap Linkage Disequilibrium report
TEPP

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEPP Gene

Disorders for TEPP Gene

Relevant External Links for TEPP

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEPP

No disorders were found for TEPP Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEPP Gene

Publications for TEPP Gene

  1. TEPP, a new gene specifically expressed in testis, prostate, and placenta and well conserved in chordates. (PMID: 14652002) Bera T.K. … Pastan I.H. (Biochem. Biophys. Res. Commun. 2003) 2 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TEPP Gene

Sources for TEPP Gene

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