TEPP Gene
protein-coding GIFtS: 40
GCID: GC16P058010
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testis, prostate and placenta expressed
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Aliases
for TEPP gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Testis, Prostate And Placenta Expressed1 2 | | Testis, Prostate And Placenta-Expressed Protein2 | | Testis/Prostate/Placenta-Expressed Protein2 |
Export aliases for TEPP gene to outside databasesPrevious GC identifers: GC16P057785 GC16P056567 GC16P043877 |
Summaries
for TEPP gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TEPP gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000016.9 NC_018927.1 NT_010498.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TEPP gene promoter:
GATA-3 YY1 GATA-1 GATA-2 RORalpha1 SREBP-1a FOXO4 ZID
Other transcription factors
Search SABiosciences Chromatin IP Primers for TEPP
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEPP |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 16q21 Ensembl cytogenetic band: 16q21 HGNC cytogenetic band: 16q13TEPP Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 16 GeneLoc Exon Structure GeneLoc location for GC16P058010: view genomic region
(about GC identifiers)
Start:
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58,010,339 bp from pter |
End:
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58,022,020 bp from pter |
Size:
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11,682 bases |
Orientation:
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plus strand |
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Proteins
for TEPP gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TEPP_HUMAN, Q6URK8 (See
protein sequence)Recommended Name: Testis, prostate and placenta-expressed protein precursor Size: 271 amino acids; 30717 Da
Subcellular location: Secreted (Potential)
Secondary accessions: Q6URK7Alternative splicing: 2 isoforms: Q6URK8-1 Q6URK8-2 Explore the universe of human proteins at neXtProt for TEPP: NX_Q6URK8
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q6URK8
TEPP Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_950247.2 NP_955535.2
ENSEMBL proteins: ENSP00000290871 ENSP00000401917
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005576 | extracellular region |
IEA | -- |
TEPP for ontologies About GeneDecksing
TEPP Antibody Products:
Assay Products for TEPP: |
Protein
Domains /
Families
for TEPP gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q6URK8 |
Function
for TEPP gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEPP (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEPP (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TEPP (NM_199456) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEPP | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEPP |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEPP |
2 GenomeRNAi human phenotypes for TEPP:
|
Pathways & Interactions
for TEPP gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEPP
|
Drugs & Compounds
for TEPP gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TEPP
Search CenterWatch for drugs/clinical trials and news about TEPP
|
Transcripts
for TEPP gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TEPP gene (2 alternative transcripts): NM_199046.2 NM_199456.2 Unigene Cluster for TEPP: Testis, prostate and placenta expressed Hs.132976 [show with all ESTs]Unigene Representative Sequence: NM_1990464 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000290871(uc002emv.4) ENST00000441824(uc002emw.4) ENST00000569996
ENST00000562915
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEPP (see all 5)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEPP (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): TEPP (NM_199456) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEPP | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEPP |
Additional cDNA sequence: AY363222.1 AY363223.1 BC104458.1 BC104459.1 4 DOTS entries: DT.405285 DT.40129532 DT.70102525 DT.92416901 16 AceView cDNA sequences: BX111631 NM_199456 BE859006 BF447201 AI972582 NM_199046 AY363222 BX647108 AY363223 AI675324 BX100493 AA394194 AI028639 BF980073 AA398110 AW183262
GeneLoc Exon Structure
3 Alternative Splicing Database (ASD) splice patterns (SP) for TEPP About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 |
|---|
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| SP1: | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | |
| SP3: | | | | | - | | | | | | | | - | | | | | |
ECgene alternative splicing isoforms for TEPP
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Expression
for TEPP gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TEPP expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCATTTAAGC
About this image
See TEPP Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TEPP
SOURCE GeneReport for Unigene cluster: Hs.132976
UniProtKB/Swiss-Prot: TEPP_HUMAN, Q6URK8Tissue specificity: Expressed in testis, prostate and placenta
SABiosciences Custom PCR Arrays for TEPP
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEPP
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TEPP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEPP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEPP | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEPP |
Orthologs
for TEPP gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for TEPP gene from 1/9 species (see all 9) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Tepp1 , 5 |
testis, prostate and placenta expressed1, 5 |
81.79(n)1
79.17(a)1 |
|
8 (47.12 cM)5
734071 NM_199455.11 NP_955534.11
953105665 |
ENSEMBL Gene Tree for TEPP (if available)
TreeFam Gene Tree for TEPP (if available) |
Paralogs
for TEPP gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TEPP gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 16 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TEPP (58010339 - 58022020 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TEPP: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEPP |
|
Disorders
/ Diseases
for TEPP gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TEPP for disorders About GeneDecksing
OMIM gene information: 610264
OMIM disorders: --
1  disease for TEPP: About MalaCardsprostatitis
Export disorders for TEPP gene to outside databases
|
Publications
for TEPP gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TEPP gene integrated from 9 sources:
(articles sorted by number of sources associating them with TEPP) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- TEPP, a new gene specifically expressed in testis, prostate, and placenta and well conserved in chordates. (PubMed id 14652002)1, 2, 3 Bera T.K.... Pastan I.H. (2003)
- The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for TEPP gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TEPP gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TEPP gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TEPP gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TEPP | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TEPP gene:
Search GeneIP for patents involving TEPP
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TEPP gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TEPP | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TEPP | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEPP | | | OriGene Protein Over-expression Lysate for TEPP | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TEPP | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEPP | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEPP | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TEPP | | OriGene Custom Protein Services for TEPP | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TEPP | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEPP | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEPP | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEPP | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEPP | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEPP |
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 | | | TEPP Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEPP |
|  |  |  | | | | Search ThermoFisher Antibodies for TEPP |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEPP |
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