Aliases for TEP1 Gene
External Ids for TEP1 Gene
Previous GeneCards Identifiers for TEP1 Gene
This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
GeneCards Summary for TEP1 Gene
TEP1 (Telomerase Associated Protein 1) is a Protein Coding gene. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts. GO annotations related to this gene include RNA binding and telomerase activity. An important paralog of this gene is APAF1.
UniProtKB/Swiss-Prot for TEP1 Gene
Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity).