Aliases for TEP1 Gene
External Ids for TEP1 Gene
Previous GeneCards Identifiers for TEP1 Gene
This gene product is a component of the ribonucleoprotein complex responsible for telomerase activity which catalyzes the addition of new telomeres on the chromosome ends. The telomerase-associated proteins are conserved from ciliates to humans. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
GeneCards Summary for TEP1 Gene
TEP1 (Telomerase Associated Protein 1) is a Protein Coding gene. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts. GO annotations related to this gene include RNA binding and telomerase activity.
UniProtKB/Swiss-Prot for TEP1 Gene
Component of the telomerase ribonucleoprotein complex that is essential for the replication of chromosome termini. Also component of the ribonucleoprotein vaults particle, a multi-subunit structure involved in nucleo-cytoplasmic transport. Responsible for the localizing and stabilizing vault RNA (vRNA) association in the vault ribonucleoprotein particle. Binds to TERC (By similarity).