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TENM1 Gene

protein-coding   GIFtS: 41
GCID: GC0XM123511

Teneurin Transmembrane Protein 1

(Previous names: tenascin M, odz, odd Oz/ten-m homolog 1 (Drosophila))
(Previous symbols: ODZ3, TNM, ODZ1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Teneurin Transmembrane Protein 11 2 3     Odz, Odd Oz/Ten-M Homolog 12
ODZ11 2 3 5     Odz, Odd Oz/Ten-M Homolog 1(Drosophila)2
TNM12 3 5     ten-12
ODZ31 2     Tenascin M12
TNM1 2     tenascin-M12
Protein Odd Oz/Ten-M Homolog 12 3     Teneurin 12
Odz, Odd Oz/Ten-M Homolog 1 (Drosophila)1     teneurin-12
Tenascin M1     Ten-13
TEN-M12     Ten-m13
Odz (Odd Oz/Ten-M, Drosophila) Homolog 32     Tenascin-M13

External Ids:    HGNC: 81171   Entrez Gene: 101782   Ensembl: ENSG000000096947   OMIM: 3005885   UniProtKB: Q9UKZ43   

Export aliases for TENM1 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TENM1 Gene:
The protein encoded by this gene belongs to the tenascin family and teneurin subfamily. It is expressed in the
neurons and may function as a cellular signal transducer. Several alternatively spliced transcript variants
encoding different isoforms have been found for this gene. (provided by RefSeq, Sep 2009)

GeneCards Summary for TENM1 Gene:
TENM1 (teneurin transmembrane protein 1) is a protein-coding gene. GO annotations related to this gene include heparin binding and protein homodimerization activity. An important paralog of this gene is TENM2.

UniProtKB/Swiss-Prot: TEN1_HUMAN, Q9UKZ4
Function: Involved in neural development, regulating the establishment of proper connectivity within the nervous
system. May function as a cellular signal transducer (By similarity)
Function: Teneurin C-terminal-associated peptide: Plays a role in the regulation of neuroplasticity in the limbic
system. Mediates a rapid reorganization of actin- and tubulin-based cytoskeleton elements with an increase in
dendritic arborization and spine density formation of neurons in the hippocampus and amygdala. Induces BDNF
transcription inhibition in neurons. Activates the mitogen-activated protein (MAP) kinase 2 (MEK2) and
extracellular signal-regulated kinase (ERK) cascade. Acts also as a bioactive neuroprotective peptide on limbic
neurons of the brain and regulates stress-induced behavior: attenuates alkalosis-associated necrotic cell death
and the effects of corticotropin-releasing factor (CRF) on c-fos/FOS induction and on the reinstatement of
cocaine seeking (By similarity)
Function: Ten-1 intracellular domain: Induces gene transcription activation (By similarity)

Gene Wiki entry for TENM1 (ODZ1) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_011786.17  NC_018934.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for TENM1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTENM1 promoter sequence
   Search Chromatin IP Primers for TENM1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TENM1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq25   Ensembl cytogenetic band:  Xq25   HGNC cytogenetic band: Xq25

TENM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TENM1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM123511:  view genomic region     (about GC identifiers)

Start:
123,509,753 bp from pter      End:
124,097,666 bp from pter
Size:
587,914 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TEN1_HUMAN, Q9UKZ4 (See protein sequence)
Recommended Name: Teneurin-1  
Size: 2725 amino acids; 305011 Da
Subunit: Homodimer; disulfide-linked. Heterodimer with either TENM2 or TENM3. May also form heterodimer with
TENM4. Ten-1 ICD interacts with SORBS1 (via third SH3 domain). Interacts with MBD1 (By similarity)
Miscellaneous: Teneurin C-terminal-associated peptide: Binds to the plasma membrane and may be internalized by a
receptor- and caveolae-mediated endocytosis manner to reach cytosolic compartments in a dynamin-dependent manner
(By similarity)
Secondary accessions: B2RTR5 Q5JZ17
Alternative splicing: 2 isoforms:  Q9UKZ4-1   Q9UKZ4-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TENM1: NX_Q9UKZ4

Explore proteomics data for TENM1 at MOPED

Post-translational modifications: 

  • Teneurin C-terminal-associated peptide: Derives from the plasma membrane form by proteolytic processing. Further
    proteolytic cleavage may be generated (By similarity)1
  • Glycosylation2 at Asn433, Asn905, Asn1084, Asn1550, Asn1567, Asn1663, Asn1699, Asn1757, Asn1781, Asn1842,
                                 Asn2145, Asn2285, Asn2602
  • Modification sites at PhosphoSitePlus

  • See TENM1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001156750.1  NP_001156751.1  NP_055068.2  

    ENSEMBL proteins: 
     ENSP00000360171   ENSP00000403954  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 6):
     IPR000742 EG-like_dom
     IPR027688 TENM1
     IPR011042 6-blade_b-propeller_TolB-like
     IPR013032 EGF-like_CS
     IPR009471 Ten_N

    Graphical View of Domain Structure for InterPro Entry Q9UKZ4

    ProtoNet protein and cluster: Q9UKZ4

    UniProtKB/Swiss-Prot: TEN1_HUMAN, Q9UKZ4
    Domain: EGF-like domains 2 and 5 which have an odd number of cysteines might enable the formation of
    intermolecular disulfide bonds
    Domain: Cytoplasmic proline-rich regions could serve as docking domains for intracellular SH3-containing proteins
    Similarity: Belongs to the tenascin family. Teneurin subfamily
    Similarity: Contains 8 EGF-like domains
    Similarity: Contains 5 NHL repeats
    Similarity: Contains 1 teneurin N-terminal domain
    Similarity: Contains 23 YD repeats


    Find genes that share domains with TENM1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TEN1_HUMAN, Q9UKZ4
    Function: Involved in neural development, regulating the establishment of proper connectivity within the nervous
    system. May function as a cellular signal transducer (By similarity)
    Function: Teneurin C-terminal-associated peptide: Plays a role in the regulation of neuroplasticity in the limbic
    system. Mediates a rapid reorganization of actin- and tubulin-based cytoskeleton elements with an increase in
    dendritic arborization and spine density formation of neurons in the hippocampus and amygdala. Induces BDNF
    transcription inhibition in neurons. Activates the mitogen-activated protein (MAP) kinase 2 (MEK2) and
    extracellular signal-regulated kinase (ERK) cascade. Acts also as a bioactive neuroprotective peptide on limbic
    neurons of the brain and regulates stress-induced behavior: attenuates alkalosis-associated necrotic cell death
    and the effects of corticotropin-releasing factor (CRF) on c-fos/FOS induction and on the reinstatement of
    cocaine seeking (By similarity)
    Function: Ten-1 intracellular domain: Induces gene transcription activation (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008201heparin binding TAS10341219
    GO:0042803protein homodimerization activity ISS--
    GO:0046982protein heterodimerization activity ISS--
         
    Find genes that share ontologies with TENM1           About GenesLikeMe


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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TEN1_HUMAN, Q9UKZ4: Cell membrane; Single-pass membrane protein (By similarity)
    TEN1_HUMAN, Q9UKZ4: Ten-1 intracellular domain: Nucleus (By similarity). Nucleus speckle (By similarity).
    Nucleus matrix (By similarity). Cytoplasm, cytoskeleton (By similarity)
    TEN1_HUMAN, Q9UKZ4: Teneurin C-terminal-associated peptide: Nucleus (By similarity). Cytoplasm (By similarity).
    Cell membrane (By similarity). Note=Colocalizes with the dystroglycan complex at the cell membrane in hippocampal
    cells. Binds hippocampal cell membranes and is incorporated in the cytoplasm by endocytosis in a
    caveoli-dependent manner. Upon cell internalization is transported arround and in the nucleus (By similarity)

    Gene Ontology (GO): Selected cellular component terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region TAS10341219
    GO:0005634nucleus ISS--
    GO:0005737cytoplasm ISS--
    GO:0005783endoplasmic reticulum ISS--
    GO:0005794Golgi apparatus ISS--

    Find genes that share ontologies with TENM1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TENM1
    Interactions:

        Search GeneGlobe Interaction Network for TENM1

    Gene Ontology (GO): Selected biological process terms (see all 13):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-templated IEA--
    GO:0006359regulation of transcription from RNA polymerase III promoter ISS--
    GO:0006950response to stress IEA--
    GO:0006955immune response TAS10556288
    GO:0007165signal transduction ----

    Find genes that share ontologies with TENM1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for TENM1 (TEN1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TENM1 gene (3 alternative transcripts): 
    NM_001163278.1  NM_001163279.1  NM_014253.3  

    Unigene Cluster for TENM1:

    Teneurin transmembrane protein 1
    Hs.23796  [show with all ESTs]
    Unigene Representative Sequence: NM_001163278
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000371130(uc004euj.3) ENST00000461429 ENST00000422452(uc011muj.2 uc010nqy.3)

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    Additional mRNA sequence: 

    AF100772.1 BC030766.2 BC140783.1 BC144542.1 BC144543.1 HE578281.1 

    5 DOTS entries:

    DT.91785063  DT.100009321  DT.100847364  DT.95174592  DT.95106234 

    Selected AceView cDNA sequences (see all 48):

    AA331486 AI498402 AW779760 AA323193 BX506934 AA235370 AK055765 AL602335 
    AI016320 BX478232 AI375997 AF100772 BX951531 CF454574 N45526 NM_014253 
    BC030766 BX457474 BX470621 BE168542 AI913631 F07491 AW296554 BX494675 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TENM1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TENM1 Expression
    About this image


    TENM1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Brain (Nervous System)
             Adult Dopaminergic Neurons Ventral Tegmental Area
     
     Neurons
             Adult Dopaminergic Neurons Ventral Tegmental Area
    TENM1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TENM1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.23796

    UniProtKB/Swiss-Prot: TEN1_HUMAN, Q9UKZ4
    Tissue specificity: Expressed in fetal brain

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TENM1 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tenm11 , 5 odd Oz/ten-m homolog 1 (Drosophila)5
    teneurin transmembrane protein 11
    91.33(n)1
    97(a)1
      X (23.21 cM)5
    239631  NM_011855.31  NP_035985.21 
     425278665 
    chicken
    (Gallus gallus)
    Aves ODZ11 odz, odd Oz/ten-m homolog 1 (Drosophila) 80.15(n)
    89.91(a)
      395668  NM_204862.1  NP_990193.1 
    lizard
    (Anolis carolinensis)
    Reptilia TENM16
    teneurin transmembrane protein 1
    88(a)
    1 ↔ 1
    GL343202.1(2315634-2670635)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia tenm11 teneurin transmembrane protein 1 75.25(n)
    83(a)
      100493796  XM_002931822.2  XP_002931868.2 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5630941 novel protein similar to vertebrate odz, odd Oz/ten-m more 64.38(n)
    66.49(a)
      563094  XM_686460.6  XP_691552.5 


    ENSEMBL Gene Tree for TENM1 (if available)
    TreeFam Gene Tree for TENM1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TENM1 gene
    TENM22  WIF12  TENM42  TENM32  VWDE2  
    4 SIMAP similar genes for TENM1 using alignment to 1 protein entry:     TEN1_HUMAN:
    ODZ1    TENM4    TENM3    TENM2

    Find genes that share paralogs with TENM1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TENM1 (see all 7971)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0365964
    A breast cancer sample4--see VAR_0365962 L F mis40--------
    VAR_0365994
    A breast cancer sample4--see VAR_0365992 Q H mis40--------
    VAR_0365974
    A breast cancer sample4--see VAR_0365972 V I mis40--------
    VAR_0366004
    A colorectal cancer sample4--see VAR_0366002 L F mis40--------
    VAR_0365984
    A colorectal cancer sample4--see VAR_0365982 F V mis40--------
    rs1811845411,2
    --123464429(+) AAATGG/TTCACT 3 -- ds50010--------
    rs66492081,2
    C--123464676(+) AAAGTA/GCTTTT 3 -- ut310--------
    rs1842908761,2
    --123464851(+) TTCAGC/TACAGG 3 -- ut310--------
    rs1887353551,2
    --123465126(+) CATGAA/TTCATA 3 -- ut310--------
    rs1814476251,2
    --123465189(+) AGGTTA/GAAGTC 3 -- ut310--------

    HapMap Linkage Disequilibrium report for TENM1 (123509753 - 123759753 bp, first 250kb of TENM1)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TENM1: --
    Human Gene Mutation Database (HGMD): TENM1
    Locus Specific Mutation Databases (LSDB): TENM1

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300588    OMIM disorders: --


    Find genes that share disorders with TENM1           About GenesLikeMe


    Export disorders for TENM1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TENM1 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with TENM1)
        Utopia: connect your pdf to the dynamic
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    1. Teneurin-1, a vertebrate homologue of the Drosophila pair-rule gene ten-m, is a neuronal protein with a novel type of heparin-binding domain. (PubMed id 10341219)1, 2, 3, 9 Minet A.D....Chiquet-Ehrismann R. (J. Cell Sci. 1999)
    2. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    3. Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25. (PubMed id 10331952)1, 3 Ben-Zur T. and Wides R. (Genomics 1999)
    4. Epstein-Barr virus-negative boys with non-Hodgkin lymphoma are mutated in the SH2D1A gene, as are patients with X-linked lymphoproliferative disease (XLP). (PubMed id 10556288)1, 2 Brandau O....Meindl A. (Hum. Mol. Genet. 1999)
    5. The intracellular domain of teneurin-1 interacts with MBD1 and CAP/ponsin resulting in subcellular codistribution and translocation to the nuclear matrix. (PubMed id 15777793)1, 9 Nunes S.M....Chiquet-Ehrismann R. (Exp. Cell Res. 2005)
    6. Genome-wide meta-analysis of systolic blood pressure in children with sickle cell disease. (PubMed id 24058526)1 Bhatnagar P....Arking D.E. (PLoS ONE 2013)
    7. Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13). (PubMed id 22952603)1 Hart A.B....Palmer A.A. (PLoS ONE 2012)
    8. Skin lesions in a boy with X-linked lymphoproliferative disorder: comparison of 5 SH2D1A deletion cases. (PubMed id 22271700)1 MejstrA-kovA! E....SedlA!cek Z. (Pediatrics 2012)
    9. Genome-wide analysis of polymorphisms associated with cytokine responses in smallpox vaccine recipients. (PubMed id 22610502)1 Kennedy R.B....Poland G.A. (Hum. Genet. 2012)
    10. Human teneurin-1 is a direct target of the homeobox transcription factor EMX2 at a novel alternate promoter. (PubMed id 21651764)1 Beckmann J....Chiquet-Ehrismann R. (BMC Dev. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10178 HGNC: 8117 AceView: ODZ1 Ensembl:ENSG00000009694 euGenes: HUgn10178
    ECgene: TENM1 H-InvDB: TENM1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TENM1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TENM1 gene:
    Search GeneIP for patents involving TENM1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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