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Aliases for TEN1-CDK3 Gene

Subcategory (RNA class) for TEN1-CDK3 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for TEN1-CDK3 Gene

  • TEN1-CDK3 Readthrough (NMD Candidate) 2 3 5
  • TEN1-CDK3 Readthrough (Non-Protein Coding) 2 3
  • C17orf106-CDK3 3

External Ids for TEN1-CDK3 Gene

Previous GeneCards Identifiers for TEN1-CDK3 Gene

  • GC17U901665
  • GC17P073981

Summaries for TEN1-CDK3 Gene

Entrez Gene Summary for TEN1-CDK3 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring TEN1 telomerase capping complex subunit homolog (S. cerevisiae) and cyclin-dependent kinase 3 (CDK3) genes. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Oct 2011]

GeneCards Summary for TEN1-CDK3 Gene

TEN1-CDK3 (TEN1-CDK3 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is TEN1.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEN1-CDK3 Gene

Genomics for TEN1-CDK3 Gene

Regulatory Elements for TEN1-CDK3 Gene

Enhancers for TEN1-CDK3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G075969 1.2 Ensembl ENCODE 0.4 -9.0 -8993 1.7 ATF1 CREB3L1 ARNT TCF12 ZNF766 ELK1 GATA2 FOS NCOA1 REST UNK CDK3 ENSG00000267342 ACOX1 ENSG00000267801 TRIM65 NUP85 NT5C TEN1 TEN1-CDK3
GH17G075958 0.8 ENCODE 0.4 -19.4 -19438 1.9 CTCF PKNOX1 TFAP4 FOXA2 ATF1 SAP130 ARID4B ZNF2 RAD21 GATA3 CDK3 EVPL ACOX1 MRPL38 EXOC7 AANAT UBE2O TEN1-CDK3 TEN1 ENSG00000267615
GH17G075974 0.4 ENCODE 0.7 -4.5 -4463 0.2 ZBTB33 CDK3 TEN1-CDK3 TEN1 ENSG00000267615
GH17G075976 0.4 ENCODE 0.7 -4.7 -4683 0.2 HNF4A CREM TEN1-CDK3 TEN1 ENSG00000267615
GH17G075950 0.6 ENCODE 0.3 -28.2 -28183 0.2 PAF1 SMARCE1 GATA2 NCOR1 TAL1 MYC ENSG00000267615 TEN1-CDK3 TEN1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TEN1-CDK3 on UCSC Golden Path with GeneCards custom track

Promoters for TEN1-CDK3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000098484 -117 2601 MLX CREB3L1 ZFP64 DMAP1 YY1 SLC30A9 ZNF143 SP3 NFYC SSRP1

Genomic Location for TEN1-CDK3 Gene

Chromosome:
17
Start:
75,979,217 bp from pter
End:
76,005,999 bp from pter
Size:
26,783 bases
Orientation:
Plus strand

Genomic View for TEN1-CDK3 Gene

Genes around TEN1-CDK3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEN1-CDK3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEN1-CDK3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEN1-CDK3 Gene

Proteins for TEN1-CDK3 Gene

Post-translational modifications for TEN1-CDK3 Gene

No Post-translational modifications

Other Protein References for TEN1-CDK3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TEN1-CDK3 Gene

Domains & Families for TEN1-CDK3 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TEN1-CDK3 Gene

Function for TEN1-CDK3 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TEN1-CDK3 Gene

Localization for TEN1-CDK3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TEN1-CDK3 Gene

Pathways & Interactions for TEN1-CDK3 Gene

SuperPathways for TEN1-CDK3 Gene

No Data Available

Interacting Proteins for TEN1-CDK3 Gene

Gene Ontology (GO) - Biological Process for TEN1-CDK3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEN1-CDK3 Gene

Drugs & Compounds for TEN1-CDK3 Gene

No Compound Related Data Available

Transcripts for TEN1-CDK3 Gene

mRNA/cDNA for TEN1-CDK3 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TEN1-CDK3 Gene

No ASD Table

Relevant External Links for TEN1-CDK3 Gene

GeneLoc Exon Structure for
TEN1-CDK3
ECgene alternative splicing isoforms for
TEN1-CDK3

Expression for TEN1-CDK3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TEN1-CDK3 Gene

Protein differential expression in normal tissues from HIPED for TEN1-CDK3 Gene

This gene is overexpressed in Heart (37.8) and Brain (31.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for TEN1-CDK3 Gene



Protein tissue co-expression partners for TEN1-CDK3 Gene

genes like me logo Genes that share expression patterns with TEN1-CDK3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEN1-CDK3 Gene

Orthologs for TEN1-CDK3 Gene

Evolution for TEN1-CDK3 Gene

ENSEMBL:
Gene Tree for TEN1-CDK3 (if available)
TreeFam:
Gene Tree for TEN1-CDK3 (if available)

No data available for Orthologs for TEN1-CDK3 Gene

Paralogs for TEN1-CDK3 Gene

Paralogs for TEN1-CDK3 Gene

genes like me logo Genes that share paralogs with TEN1-CDK3: view

Variants for TEN1-CDK3 Gene

Sequence variations from dbSNP and Humsavar for TEN1-CDK3 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs777937235 Likely pathogenic 75,978,627(+) CATAA(C/G)GCTGG upstream-variant-2KB, reference, missense, utr-variant-5-prime
rs3760132 Likely benign 75,979,390(+) AGAAA(C/G/T)TGCCC nc-transcript-variant, utr-variant-5-prime
rs145082938 Uncertain significance 75,978,994(+) TCTCG(A/G)GGCTG upstream-variant-2KB, reference, missense, utr-variant-5-prime
rs543914514 Uncertain significance 75,979,259(+) GTGAC(A/T)GCGGC nc-transcript-variant, utr-variant-5-prime
rs575138461 Uncertain significance 75,979,246(+) CTTTG(A/G)CGCGT nc-transcript-variant, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for TEN1-CDK3 Gene

Variant ID Type Subtype PubMed ID
nsv833546 CNV loss 17160897

Relevant External Links for TEN1-CDK3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEN1-CDK3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TEN1-CDK3 Gene

Disorders for TEN1-CDK3 Gene

Relevant External Links for TEN1-CDK3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEN1-CDK3

No disorders were found for TEN1-CDK3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEN1-CDK3 Gene

Publications for TEN1-CDK3 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 64
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 64

Products for TEN1-CDK3 Gene

Sources for TEN1-CDK3 Gene

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