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Aliases for TEN1-CDK3 Gene

Subcategory (RNA class) for TEN1-CDK3 Gene

ncRNA

Quality Score for this RNA gene is

3

Aliases for TEN1-CDK3 Gene

  • TEN1-CDK3 Readthrough (NMD Candidate) 2 3 5
  • TEN1-CDK3 Readthrough (Non-Protein Coding) 2 3
  • C17orf106-CDK3 3

External Ids for TEN1-CDK3 Gene

Previous GeneCards Identifiers for TEN1-CDK3 Gene

  • GC17U901665
  • GC17P073981

Summaries for TEN1-CDK3 Gene

Entrez Gene Summary for TEN1-CDK3 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring TEN1 telomerase capping complex subunit homolog (S. cerevisiae) and cyclin-dependent kinase 3 (CDK3) genes. The read-through transcript is a candidate for nonsense-mediated mRNA decay (NMD), and is therefore unlikely to produce a protein product. [provided by RefSeq, Oct 2011]

GeneCards Summary for TEN1-CDK3 Gene

TEN1-CDK3 (TEN1-CDK3 Readthrough (NMD Candidate)) is an RNA Gene, and is affiliated with the ncRNA class. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is TEN1.

Additional gene information for TEN1-CDK3 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEN1-CDK3 Gene

Genomics for TEN1-CDK3 Gene

GeneHancer (GH) Regulatory Elements for TEN1-CDK3 Gene

Promoters and enhancers for TEN1-CDK3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I075975 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE dbSUPER 550.8 +1.0 977 10.1 CLOCK MLX ZFP64 YBX1 DMAP1 YY1 SLC30A9 ZNF213 ZNF143 SP3 ACOX1 TEN1 TEN1-CDK3 SRSF2 UBE2O H3F3B UNK ENSG00000267342 GGA3 SAP30BP
GH17I075999 Promoter/Enhancer 1.5 EPDnew ENCODE dbSUPER 550.3 +21.3 21303 1.3 HDGF FOXA2 ARID4B ZNF2 ZNF48 RAD21 RARA ETS1 GLIS2 HSF1 CDK3 TEN1-CDK3 TEN1 ACOX1
GH17I075995 Enhancer 1.4 Ensembl ENCODE dbSUPER 0.4 +18.0 18048 4.1 HDGF FOXA2 MLX ZFP64 ARID4B DMAP1 ZNF48 ETS1 YY1 SLC30A9 TEN1 CDK3 MRPS7 TEN1-CDK3 ACOX1
GH17I075969 Enhancer 1.1 Ensembl ENCODE 0.4 -9.0 -8992 1.7 SMAD1 ATF1 ARNT TCF12 ZNF766 GATA2 E2F8 ATF7 NCOA1 REST ACOX1 TSEN54 ARMC7 CDK3 TEN1 TEN1-CDK3 ENSG00000267615
GH17I076002 Enhancer 1.4 Ensembl ENCODE dbSUPER 0.3 +25.2 25249 3.5 FOXA2 MLX ZFP64 ARID4B DMAP1 ZNF48 ETS1 YY1 TCF12 SLC30A9 TEN1 ACOX1 CDK3 TRIM65 PIR42105 EVPL TEN1-CDK3
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TEN1-CDK3 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TEN1-CDK3 Gene

Genomic Locations for TEN1-CDK3 Gene
chr17:75,979,217-76,005,999
(GRCh38/hg38)
Size:
26,783 bases
Orientation:
Plus strand
chr17:73,975,298-74,002,080
(GRCh37/hg19)

Genomic View for TEN1-CDK3 Gene

Genes around TEN1-CDK3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEN1-CDK3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEN1-CDK3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEN1-CDK3 Gene

Proteins for TEN1-CDK3 Gene

Post-translational modifications for TEN1-CDK3 Gene

No Post-translational modifications

Other Protein References for TEN1-CDK3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TEN1-CDK3 Gene

Domains & Families for TEN1-CDK3 Gene

Gene Families for TEN1-CDK3 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TEN1-CDK3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TEN1-CDK3 Gene

Function for TEN1-CDK3 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TEN1-CDK3 Gene

Localization for TEN1-CDK3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for TEN1-CDK3 Gene

Pathways & Interactions for TEN1-CDK3 Gene

SuperPathways for TEN1-CDK3 Gene

No Data Available

Interacting Proteins for TEN1-CDK3 Gene

Gene Ontology (GO) - Biological Process for TEN1-CDK3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEN1-CDK3 Gene

Drugs & Compounds for TEN1-CDK3 Gene

No Compound Related Data Available

Transcripts for TEN1-CDK3 Gene

mRNA/cDNA for TEN1-CDK3 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TEN1-CDK3 Gene

No ASD Table

Relevant External Links for TEN1-CDK3 Gene

GeneLoc Exon Structure for
TEN1-CDK3
ECgene alternative splicing isoforms for
TEN1-CDK3

Expression for TEN1-CDK3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TEN1-CDK3 Gene

Protein differential expression in normal tissues from HIPED for TEN1-CDK3 Gene

This gene is overexpressed in Heart (37.8) and Brain (31.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for TEN1-CDK3 Gene



Protein tissue co-expression partners for TEN1-CDK3 Gene

genes like me logo Genes that share expression patterns with TEN1-CDK3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEN1-CDK3 Gene

Orthologs for TEN1-CDK3 Gene

Evolution for TEN1-CDK3 Gene

ENSEMBL:
Gene Tree for TEN1-CDK3 (if available)
TreeFam:
Gene Tree for TEN1-CDK3 (if available)

No data available for Orthologs for TEN1-CDK3 Gene

Paralogs for TEN1-CDK3 Gene

Paralogs for TEN1-CDK3 Gene

genes like me logo Genes that share paralogs with TEN1-CDK3: view

Variants for TEN1-CDK3 Gene

Sequence variations from dbSNP and Humsavar for TEN1-CDK3 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs145082938 likely-benign, uncertain-significance, not provided, Pseudoneonatal adrenoleukodystrophy 75,978,994(+) G/A upstream_transcript_variant
rs3760132 likely-benign, Pseudoneonatal adrenoleukodystrophy 75,979,390(+) C/G/T non_coding_transcript_variant
rs543914514 uncertain-significance, Pseudoneonatal adrenoleukodystrophy 75,979,259(+) A/T non_coding_transcript_variant
rs575138461 uncertain-significance, Pseudoneonatal adrenoleukodystrophy 75,979,246(+) G/A non_coding_transcript_variant
rs777937235 likely-pathogenic, Pseudoneonatal adrenoleukodystrophy 75,978,627(+) C/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for TEN1-CDK3 Gene

Variant ID Type Subtype PubMed ID
nsv833546 CNV loss 17160897

Additional Variant Information for TEN1-CDK3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEN1-CDK3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for TEN1-CDK3 Gene

Disorders for TEN1-CDK3 Gene

Additional Disease Information for TEN1-CDK3

No disorders were found for TEN1-CDK3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEN1-CDK3 Gene

Publications for TEN1-CDK3 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 58
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 58

Products for TEN1-CDK3 Gene

Sources for TEN1-CDK3 Gene

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