Aliases for TEN1 Gene
External Ids for TEN1 Gene
Previous Symbols for TEN1 Gene
C17ORF106, or TEN1, appears to function in a telomere-associated complex with STN1 (OBFC1; MIM 613128) and CTC1 (C17ORF68; MIM 613129) (Miyake et al., 2009 [PubMed 19854130]).[supplied by OMIM, Nov 2009]
GeneCards Summary for TEN1 Gene
TEN1 (TEN1 CST Complex Subunit) is a Protein Coding gene.
UniProtKB/Swiss-Prot for TEN1 Gene
Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.