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TEFM Gene

protein-coding   GIFtS: 45
GCID: GC17M029227

Transcription Elongation Factor, Mitochondrial

(Previous name: chromosome 17 open reading frame 42)
(Previous symbol: C17orf42)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Transcription Elongation Factor, Mitochondrial1 2
C17orf421 2 3
Chromosome 17 Open Reading Frame 421
Transcription Elongation Factor Of Mitochondria2

External Ids:    HGNC: 262231   Entrez Gene: 797362   Ensembl: ENSG000001721717   UniProtKB: Q96QE53   

Export aliases for TEFM gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TEFM Gene:
TEFM (transcription elongation factor, mitochondrial) is a protein-coding gene. GO annotations related to this gene include DNA polymerase processivity factor activity and nucleic acid binding.

UniProtKB/Swiss-Prot: TEFM_HUMAN, Q96QE5
Function: Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates
transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000017.10  NT_010783.16  NC_018928.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for TEFM
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TEFM

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TEFM


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17q11.2

TEFM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TEFM gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M029227:  view genomic region     (about GC identifiers)

Start:
29,224,354 bp from pter      End:
29,233,838 bp from pter
Size:
9,485 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TEFM_HUMAN, Q96QE5 (See protein sequence)
Recommended Name: Transcription elongation factor, mitochondrial precursor  
Size: 360 amino acids; 41676 Da
Subunit: Interacts with POLRMT
Sequence caution: Sequence=AAH73169.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=BAB15468.1;
Type=Erroneous translation; Note=Wrong choice of CDS;
Secondary accessions: E1P655 Q6GPG5 Q6PJ19 Q96H04 Q9H5Z9
Alternative splicing: 2 isoforms:  Q96QE5-1   Q96QE5-4   

Explore the universe of human proteins at neXtProt for TEFM: NX_Q96QE5

Explore proteomics data for TEFM at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys124, Lys137, Lys310
  • Modification sites at PhosphoSitePlus

  • See TEFM Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_078959.3  
    ENSEMBL proteins: 
     ENSP00000462963   ENSP00000306574   ENSP00000462973  

    TEFM Human Recombinant Protein Products:

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    Novus Biologicals TEFM Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TEFM

     
    Search eBioscience for Proteins for TEFM 

     
    antibodies-online proteins for TEFM (4 products) 

     
    antibodies-online peptides for TEFM

    TEFM Antibody Products:

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    ThermoFisher Antibodies for TEFM
    LSBio Antibodies in human, mouse, rat for TEFM
    antibodies-online antibodies for TEFM (14 products) 

    TEFM Assay Products:

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    Cloud-Clone Corp. ELISAs for TEFM
    Cloud-Clone Corp. CLIAs for TEFM
    Search eBioscience for ELISAs for TEFM 
    Search antibodies-online for kits for TEFM 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR012337 RNaseH-like_dom
     IPR010994 RuvA_2-like
     IPR023097 Tex_RuvX-like_dom

    Graphical View of Domain Structure for InterPro Entry Q96QE5

    ProtoNet protein and cluster: Q96QE5

    UniProtKB/Swiss-Prot: TEFM_HUMAN, Q96QE5
    Similarity: Belongs to the TEFM family


    Find genes that share domains with TEFM           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TEFM_HUMAN, Q96QE5
    Function: Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates
    transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery

         Gene Ontology (GO): 5 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding ----
    GO:0005515protein binding IPI--
    GO:0008821NOT crossover junction endodeoxyribonuclease activity IDA--
    GO:0030337DNA polymerase processivity factor activity IDA--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with TEFM           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TEFM:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TEFM
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TEFM

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TEFM
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TEFM

    miRNA
    Products:
        
    miRTarBase miRNAs that target TEFM:
    hsa-mir-17-5p (MIRT050920)

    Block miRNA regulation of human, mouse, rat TEFM using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TEFM
    SwitchGear 3'UTR luciferase reporter plasmidTEFM 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TEFM

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEFM

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TEFM_HUMAN, Q96QE5: Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005759mitochondrial matrix IDA--
    GO:0030529ribonucleoprotein complex IDA--
    GO:0042645mitochondrial nucleoid IDA--

    Find genes that share ontologies with TEFM           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TEFM
    Interactions:

        Search GeneGlobe Interaction Network for TEFM

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for TEFM (Q96QE52, 3 ENSP000003065744) via UniProtKB, MINT, STRING, and/or I2D (see all 254)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SPCS2Q150052, 3, ENSP000002636724MINT-64585 I2D: score=4 STRING: ENSP00000263672
    KBTBD7Q8WVZ93, ENSP000003687974I2D: score=3 STRING: ENSP00000368797
    ICT1Q141972, ENSP000003015854MINT-8079030 STRING: ENSP00000301585
    GABARAPO951663I2D: score=1 
    GABARAPL1Q9H0R83I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006119oxidative phosphorylation IMP--
    GO:0006259DNA metabolic process IDA--
    GO:0006264NOT mitochondrial DNA replication IMP--
    GO:0006355regulation of transcription, DNA-templated IEA--
    GO:0006390transcription from mitochondrial promoter IMP--

    Find genes that share ontologies with TEFM           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TEFM



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TEFM gene: 
    NM_024683.3  

    Unigene Cluster for TEFM:

    Transcription elongation factor, mitochondrial
    Hs.317340  [show with all ESTs]
    Unigene Representative Sequence: BC064631
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000579183 ENST00000581216(uc002hfu.2 uc002hfv.2 uc010wbs.1)
    ENST00000306049 ENST00000580840(uc002hfw.2) ENST00000541382
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TEFM using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TEFM
    SwitchGear 3'UTR luciferase reporter plasmidTEFM 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TEFM
    Clone
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    GenScript Custom all cDNA clones Services for TEFM
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TEFM
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEFM
    Primer
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    OriGene qPCR primer pairs and template standards for TEFM
    OriGene qSTAR qPCR primer pairs in human, mouse for TEFM
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TEFM
      QuantiTect SYBR Green Assays in human, mouse, rat TEFM
      QuantiFast Probe-based Assays in human, mouse, rat TEFM

    Additional mRNA sequence: 

    AF086465.1 AJ314645.1 AK298495.1 BC009025.2 BC064631.1 BC073169.1 CR457360.1 

    10 DOTS entries:

    DT.100793086  DT.100793085  DT.120972603  DT.91748857  DT.410828  DT.305623  DT.120973080  DT.410829 
    DT.95372721  DT.120973129 

    Selected AceView cDNA sequences (see all 107):

    AI718270 BQ776248 AI718262 AW072389 CR602324 BE350591 BQ011872 AI081824 
    AI276174 AA251657 AA418363 BQ003763 AJ314645 AI084243 AK026382 AF086465 
    CA422718 W81379 BC009025 AI093701 AI140895 AA477289 AW510322 AA352491 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TEFM    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c
    SP1:                    -                                 
    SP2:                    -     -                           
    SP3:                    -                                 
    SP4:                                                      


    ECgene alternative splicing isoforms for TEFM

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TEFM expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTATTGGAAA
    TEFM Expression
    About this image

    TEFM Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TEFM Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.317340
        Custom PCR Arrays for TEFM
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEFM

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TEFM gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tefm1 , 5 RIKEN cDNA 1110002N22 gene5
    transcription elongation factor, mitochondrial1
    76.19(n)1
    68.51(a)1
      11 (47.53 cM)5
    685501  NM_183275.21  NP_899098.21 
     801366785 
    lizard
    (Anolis carolinensis)
    Reptilia TEFM6
    transcription elongation factor, mitochondrial
    54(a)
    1 ↔ 1
    GL343198.1(1552840-1557077)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.184642 Xenopus laevis transcribed sequence with moderate similarity more 79.62(n)    BG347812.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tefm1 transcription elongation factor, mitochondrial 55.97(n)
    48.46(a)
      566236  NM_001080026.1  NP_001073495.1 


    ENSEMBL Gene Tree for TEFM (if available)
    TreeFam Gene Tree for TEFM (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TEFM (see all 208)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1885117071,2
    --29225547(+) TTTTTC/TAGTAG 1 -- int10--------
    rs1931022591,2
    --29225663(+) CATGCA/GTGGCC 1 -- int10--------
    rs1840480481,2
    --29225717(+) CCCTAC/TTTTAA 1 -- int10--------
    rs1867894601,2
    --29225802(+) TGTCAA/GTTTGG 1 -- int10--------
    rs732656121,2
    C,F--29225983(+) AACACA/GTTAAC 1 -- int15Minor allele frequency- G:0.14WA NA EA 362
    rs1414362061,2
    --29226073(+) AGAATG/TTAAAC 1 -- ut310--------
    rs1998225651,2
    --29226143(+) TGTTAC/TGTTAG 1 -- ut310--------
    rs24331,2,,4
    C,F,H--29226228(-) AAGCTA/GTTGCC 2 I V mis125Minor allele frequency- G:0.12MN NS EA NA WA EU 4143
    rs31925481,2
    H--29226247(-) CTTTAT/AGATTC 2 /* /Y stg15Minor allele frequency- A:0.00MN NS EA 580
    rs617431571,2
    C,F--29226348(+) CAGTAT/AAGAAT 2 /I /L mis12Minor allele frequency- A:0.37NS WA 186

    HapMap Linkage Disequilibrium report for TEFM (29224354 - 29233838 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TEFM: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TEFM
    DNA2.0 Custom Variant and Variant Library Synthesis for TEFM

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TEFM gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with TEFM)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. TEFM (c17orf42) is necessary for transcription of human mtDNA. (PubMed id 21278163)1, 2, 3 Minczuk M.... Holt I.J. (Nucleic Acids Res. 2011)
    2. Molecular characterization and gene content of breakpoint boundaries in patients with neurofibromatosis type 1 with 17q11.2 microdeletions. (PubMed id 11468690)1, 2, 3 Jenne D.E.... Kehrer-Sawatzki H. (Am. J. Hum. Genet. 2001)
    3. A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions. (PubMed id 10843809)1, 3 Jenne D.E.... Thiel G. (Genomics 2000)
    4. Protein phosphatase 1I^ isoforms linked interactions in the brain. (PubMed id 23080069)1 Esteves S.L....da Cruz e Silva E.F. (J. Mol. Neurosci. 2013)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    6. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    7. Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (Nature 2010)
    8. Dynamics of cullin-RING ubiquitin ligase network revealed by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (Cell 2010)
    9. RNF135 mutations are not present in patients with Sotos syndrome-like features. (PubMed id 19291764)1 Visser R.... Losekoot M. (Am. J. Med. Genet. A 2009)
    10. Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth. (PubMed id 17632510)1 Douglas J.... Rahman N. (Nat. Genet. 2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 79736 HGNC: 26223 AceView: FLJ22729 Ensembl:ENSG00000172171 euGenes: HUgn79736
    ECgene: TEFM H-InvDB: TEFM

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TEFM Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TEFM gene:
    Search GeneIP for patents involving TEFM

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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