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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TEFM Gene

protein-coding   GIFtS: 45
GCID: GC17M029227

Transcription Elongation Factor, Mitochondrial

(Previous name: chromosome 17 open reading frame 42)
(Previous symbol: C17orf42)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Transcription Elongation Factor, Mitochondrial1 2
C17orf421 2 3
Chromosome 17 Open Reading Frame 421
Transcription Elongation Factor Of Mitochondria2

External Ids:    HGNC: 262231   Entrez Gene: 797362   Ensembl: ENSG000001721717   UniProtKB: Q96QE53   

Export aliases for TEFM gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TEFM Gene: 
TEFM (transcription elongation factor, mitochondrial) is a protein-coding gene. Diseases associated with TEFM include sotos syndrome, and neurofibromatosis. GO annotations related to this gene include DNA polymerase processivity factor activity and nucleic acid binding.

UniProtKB/Swiss-Prot: TEFM_HUMAN, Q96QE5
Function: Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates
transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NC_018928.2  NT_010799.15  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for TEFM
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TEFM

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEFM


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Ensembl cytogenetic band:  17q11.2   HGNC cytogenetic band: 17q11.2

TEFM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TEFM gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M029227:  view genomic region     (about GC identifiers)

Start:
29,224,354 bp from pter      End:
29,233,838 bp from pter
Size:
9,485 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TEFM_HUMAN, Q96QE5 (See protein sequence)
Recommended Name: Transcription elongation factor, mitochondrial precursor  
Size: 360 amino acids; 41676 Da
Subunit: Interacts with POLRMT
Subcellular location: Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid
Sequence caution: Sequence=AAH73169.1; Type=Erroneous translation; Note=Wrong choice of CDS; Sequence=BAB15468.1;
Type=Erroneous translation; Note=Wrong choice of CDS;
Secondary accessions: E1P655 Q6GPG5 Q6PJ19 Q96H04 Q9H5Z9
Alternative splicing: 2 isoforms:  Q96QE5-1   Q96QE5-4   

Explore the universe of human proteins at neXtProt for TEFM: NX_Q96QE5

Explore proteomics data for TEFM at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96QE5

  • TEFM Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TEFM Protein Expression
    REFSEQ proteins: NP_078959.3  
    ENSEMBL proteins: 
     ENSP00000462963   ENSP00000306574   ENSP00000462973  

    Human Recombinant Protein Products for TEFM: 
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    Novus Biologicals TEFM Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TEFM 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005759mitochondrial matrix IDA--
    GO:0030529ribonucleoprotein complex IDA--
    GO:0042645mitochondrial nucleoid IDA--

    TEFM for ontologies           About GeneDecksing



    TEFM Antibody Products: 
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    Cloud-Clone Corp. ELISAs for TEFM 
    Cloud-Clone Corp. CLIAs for TEFM


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR012337 RNaseH-like_dom
     IPR023097 Tex_RuvX-like_dom

    Graphical View of Domain Structure for InterPro Entry Q96QE5

    ProtoNet protein and cluster: Q96QE5

    UniProtKB/Swiss-Prot: TEFM_HUMAN, Q96QE5
    Similarity: Belongs to the TEFM family


    TEFM for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TEFM_HUMAN, Q96QE5
    Function: Transcription elongation factor which increases mitochondrial RNA polymerase processivity. Regulates
    transcription of the mitochondrial genome, including genes important for the oxidative phosphorylation machinery

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0005515protein binding IPI--
    GO:0008821NOT crossover junction endodeoxyribonuclease activity IDA--
    GO:0030337DNA polymerase processivity factor activity IDA--
         
    TEFM for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for TEFM:
     Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TEFM 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TEFM

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TEFM 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TEFM 

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidTEFM 3' UTR sequence
    Inhib. RNA
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                         Customized lentivirus expression plasmids for stable overexpression of TEFM 

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEFM


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEFM

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    5/250 Interacting proteins for TEFM (Q96QE52, 3 ENSP000003065744) via UniProtKB, MINT, STRING, and/or I2D (see all 250)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SPCS2Q150052, 3, ENSP000002636724MINT-64585 I2D: score=4 STRING: ENSP00000263672
    KBTBD7Q8WVZ93, ENSP000003687974I2D: score=3 STRING: ENSP00000368797
    ICT1Q141972, ENSP000003015854MINT-8079030 STRING: ENSP00000301585
    GABARAPO951663I2D: score=1 
    GABARAPL1Q9H0R83I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006119oxidative phosphorylation IMP--
    GO:0006264NOT mitochondrial DNA replication IMP--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0006390transcription from mitochondrial promoter IMP--

    TEFM for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TEFM

    Search CenterWatch for drugs/clinical trials and news about TEFM

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TEFM gene: 
    NM_024683.3  

    Unigene Cluster for TEFM:

    Transcription elongation factor, mitochondrial
    Hs.317340  [show with all ESTs]
    Unigene Representative Sequence: BC064631
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000579183 ENST00000581216(uc002hfu.2 uc002hfv.2 uc010wbs.1)
    ENST00000306049 ENST00000580840(uc002hfw.2) ENST00000541382
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TEFM
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TEFM
    SwitchGear 3'UTR luciferase reporter plasmidTEFM 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TEFM
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEFM
    Clone
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    OriGene ORF clones in mouse, rat for TEFM
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TEFM
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEFM
    Sirion Biotech Customized lentivirus for stable overexpression of TEFM 
                         Customized lentivirus expression plasmids for stable overexpression of TEFM 
    Primer
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    OriGene qPCR primer pairs and template standards for TEFM
    OriGene qSTAR qPCR primer pairs in human, mouse for TEFM
    Search SABiosciences RT2 qPCR Primer Assays in human, mouse, rat TEFM
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEFM
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEFM

    Additional mRNA sequence: 

    AF086465.1 AJ314645.1 AK298495.1 BC009025.2 BC064631.1 BC073169.1 CR457360.1 

    10 DOTS entries:

    DT.100793086  DT.100793085  DT.120972603  DT.91748857  DT.410828  DT.305623  DT.120973080  DT.410829 
    DT.95372721  DT.120973129 

    24/107 AceView cDNA sequences (see all 107):

    BE350591 AA352491 AI718270 AA251657 BQ776248 AA454582 AW510322 CR602324 
    AW072389 NM_024683 CR619488 N72094 W81379 AI276174 AI084243 CD364654 
    AI718262 BQ011872 CR590477 AI093701 BQ003763 BM561651 CA422718 AI140895 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TEFM    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b · 4c
    SP1:                    -                                 
    SP2:                    -     -                           
    SP3:                    -                                 
    SP4:                                                      


    ECgene alternative splicing isoforms for TEFM

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TEFM expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTATTGGAAA
    TEFM Expression
    About this image


    See TEFM Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TEFM

    SOURCE GeneReport for Unigene cluster: Hs.317340
        SABiosciences Custom PCR Arrays for TEFM
    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEFM

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TEFM gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tefm1 , 5 RIKEN cDNA 1110002N22 gene5
    transcription elongation factor, mitochondrial1
    76.76(n)1
    69.12(a)1
      11 (47.53 cM)5
    685501  NM_183275.21  NP_899098.21 
     801366785 
    lizard
    (Anolis carolinensis)
    Reptilia TEFM6
    Uncharacterized protein
    50(a)
    1 ↔ 1
    GL343198.1(1552840-1557077)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.184642 Xenopus laevis transcribed sequence with moderate similarity more 79.62(n)    BG347812.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tefm1 transcription elongation factor, mitochondrial 55.97(n)
    48.46(a)
      566236  NM_001080026.1  NP_001073495.1 


    ENSEMBL Gene Tree for TEFM (if available)
    TreeFam Gene Tree for TEFM (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/208 SNPs in TEFM are shown (see all 208)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1885117071,2
    --29225547(+) TTTTTC/TAGTAG 1 -- int10--------
    rs1931022591,2
    --29225663(+) CATGCA/GTGGCC 1 -- int10--------
    rs1840480481,2
    --29225717(+) CCCTAC/TTTTAA 1 -- int10--------
    rs1867894601,2
    --29225802(+) TGTCAA/GTTTGG 1 -- int10--------
    rs732656121,2
    C,F--29225983(+) AACACA/GTTAAC 1 -- int15Minor allele frequency- G:0.14WA NA EA 362
    rs1414362061,2
    --29226073(+) AGAATG/TTAAAC 1 -- ut310--------
    rs1998225651,2
    --29226143(+) TGTTAC/TGTTAG 1 -- ut310--------
    rs24331,2,4
    C,F,H--29226228(-) AAGCTA/GTTGCC 2 I V mis125Minor allele frequency- G:0.12MN NS EA NA WA EU 4143
    rs31925481,2
    H--29226247(-) CTTTAT/AGATTC 2 /* /Y stg15Minor allele frequency- A:0.00MN NS EA 580
    rs617431571,2
    C,F--29226348(+) CAGTAT/AAGAAT 2 /I /L mis12Minor allele frequency- A:0.37NS WA 186

    HapMap Linkage Disequilibrium report for TEFM (29224354 - 29233838 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TEFM: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TEFM
    DNA2.0 Custom Variant and Variant Library Synthesis for TEFM

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for TEFM:    About MalaCards
    sotos syndrome    neurofibromatosis


    TEFM for disorders           About GeneDecksing


    Export disorders for TEFM gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TEFM gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with TEFM)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. TEFM (c17orf42) is necessary for transcription of human mtDNA. (PubMed id 21278163)1, 2, 3 Minczuk M.... Holt I.J. (2011)
    2. Molecular characterization and gene content of breakpoint boundaries in patients with neurofibromatosis type 1 with 17q11.2 microdeletions. (PubMed id 11468690)1, 2, 3 Jenne D.E....Kehrer-Sawatzki H. (2001)
    3. A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions. (PubMed id 10843809)1, 3 Jenne D.E.... Thiel G. (2000)
    4. Protein phosphatase 1g isoforms linked interactions in the brain. (PubMed id 23080069)1 Esteves S.L....da Cruz e Silva E.F. (2013)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    7. Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (2010)
    8. Dynamics of cullin-RING ubiquitin ligase network revea led by systematic quantitative proteomics. (PubMed id 21145461)1 Bennett E.J....Harper J.W. (2010)
    9. RNF135 mutations are not present in patients with Sotos syndrome-like features. (PubMed id 19291764)1 Visser R....Losekoot M. (2009)
    10. Mutations in RNF135, a gene within the NF1 microdeletion region, cause phenotypic abnormalities including overgrowth. (PubMed id 17632510)1 Douglas J.... Rahman N. (2007)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 79736 HGNC: 26223 AceView: FLJ22729 Ensembl:ENSG00000172171 euGenes: HUgn79736
    ECgene: TEFM H-InvDB: TEFM

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TEFM Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TEFM gene:
    Search GeneIP for patents involving TEFM

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     EMD Millipore Custom Antibody & Bulk Services
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     Proteins for TEFM
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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