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Aliases for TEDDM1 Gene

Aliases for TEDDM1 Gene

  • Transmembrane Epididymal Protein 1 2 3 5
  • Human Epididymis-Specific Protein 9 3 4
  • Putative Membrane Protein HE9 2 3
  • Transmembrane Protein 45C 2 3
  • Epididymal Protein 9 2 3
  • HE9 3 4
  • Epididymis Secretory Sperm Binding Protein Li 45e 3
  • HEL-S-45e 3
  • TMEM45C 3
  • EDDM9 3
  • Epdd1 3

External Ids for TEDDM1 Gene

Previous GeneCards Identifiers for TEDDM1 Gene

  • GC01M179100
  • GC01M180633
  • GC01M153603

Summaries for TEDDM1 Gene

GeneCards Summary for TEDDM1 Gene

TEDDM1 (Transmembrane Epididymal Protein 1) is a Protein Coding gene. An important paralog of this gene is TMEM45B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEDDM1 Gene

Genomics for TEDDM1 Gene

Regulatory Elements for TEDDM1 Gene

Enhancers for TEDDM1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TEDDM1 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the TEDDM1 gene promoter:

Genomic Location for TEDDM1 Gene

Chromosome:
1
Start:
182,398,117 bp from pter
End:
182,400,616 bp from pter
Size:
2,500 bases
Orientation:
Minus strand

Genomic View for TEDDM1 Gene

Genes around TEDDM1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEDDM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEDDM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEDDM1 Gene

Proteins for TEDDM1 Gene

  • Protein details for TEDDM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T9Z0-TEDM1_HUMAN
    Recommended name:
    Transmembrane epididymal protein 1
    Protein Accession:
    Q5T9Z0
    Secondary Accessions:
    • Q8IVJ0

    Protein attributes for TEDDM1 Gene

    Size:
    273 amino acids
    Molecular mass:
    31315 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEDDM1 Gene

Proteomics data for TEDDM1 Gene at MOPED

Post-translational modifications for TEDDM1 Gene

No Post-translational modifications

Other Protein References for TEDDM1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEDDM1 Gene

Domains & Families for TEDDM1 Gene

Protein Domains for TEDDM1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEDDM1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5T9Z0

UniProtKB/Swiss-Prot:

TEDM1_HUMAN :
  • Belongs to the TMEM45 family.
Family:
  • Belongs to the TMEM45 family.
genes like me logo Genes that share domains with TEDDM1: view

No data available for Gene Families for TEDDM1 Gene

Function for TEDDM1 Gene

Phenotypes for TEDDM1 Gene

genes like me logo Genes that share phenotypes with TEDDM1: view

Animal Model Products

CRISPR Products

miRNA for TEDDM1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TEDDM1 Gene

Localization for TEDDM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEDDM1 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TEDDM1 Gene COMPARTMENTS Subcellular localization image for TEDDM1 gene
Compartment Confidence
plasma membrane 3

No data available for Gene Ontology (GO) - Cellular Components for TEDDM1 Gene

Pathways & Interactions for TEDDM1 Gene

SuperPathways for TEDDM1 Gene

No Data Available

Interacting Proteins for TEDDM1 Gene

Gene Ontology (GO) - Biological Process for TEDDM1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEDDM1 Gene

Drugs & Compounds for TEDDM1 Gene

No Compound Related Data Available

Transcripts for TEDDM1 Gene

mRNA/cDNA for TEDDM1 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TEDDM1 Gene

Transmembrane epididymal protein 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TEDDM1 Gene

No ASD Table

Relevant External Links for TEDDM1 Gene

GeneLoc Exon Structure for
TEDDM1
ECgene alternative splicing isoforms for
TEDDM1

Expression for TEDDM1 Gene

mRNA expression in normal human tissues for TEDDM1 Gene

mRNA differential expression in normal tissues according to GTEx for TEDDM1 Gene

This gene is overexpressed in Testis (x7.3).

SOURCE GeneReport for Unigene cluster for TEDDM1 Gene Hs.156977

genes like me logo Genes that share expression patterns with TEDDM1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TEDDM1 Gene

Orthologs for TEDDM1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEDDM1 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Gm5531 35
  • 81.57 (n)
  • 71.97 (a)
Teddm1b 16
Gm5531 36
  • 62 (a)
OneToMany
Teddm1 36
  • 61 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia LOC469606 35
  • 98.78 (n)
  • 97.44 (a)
TEDDM1 36
  • 96 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC684709 35
  • 79.34 (n)
  • 71.48 (a)
cow
(Bos Taurus)
Mammalia TEDDM1 36
  • 61 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 64 (a)
OneToMany
-- 36
  • 67 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia TEDDM1 36
  • 26 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 25 (a)
OneToOne
Species with no ortholog for TEDDM1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEDDM1 Gene

ENSEMBL:
Gene Tree for TEDDM1 (if available)
TreeFam:
Gene Tree for TEDDM1 (if available)

Paralogs for TEDDM1 Gene

Paralogs for TEDDM1 Gene

Pseudogenes.org Pseudogenes for TEDDM1 Gene

genes like me logo Genes that share paralogs with TEDDM1: view

Variants for TEDDM1 Gene

Sequence variations from dbSNP and Humsavar for TEDDM1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
VAR_035356 -

Variation tolerance for TEDDM1 Gene

Residual Variation Intolerance Score: 42% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.59; 12.77% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEDDM1 Gene

HapMap Linkage Disequilibrium report
TEDDM1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TEDDM1 Gene

Disorders for TEDDM1 Gene

Relevant External Links for TEDDM1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEDDM1

No disorders were found for TEDDM1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEDDM1 Gene

Publications for TEDDM1 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 67

Products for TEDDM1 Gene

Sources for TEDDM1 Gene

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