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Aliases for TEDDM1 Gene

Aliases for TEDDM1 Gene

  • Transmembrane Epididymal Protein 1 2 3 5
  • Human Epididymis-Specific Protein 9 3 4
  • Putative Membrane Protein HE9 2 3
  • Transmembrane Protein 45C 2 3
  • Epididymal Protein 9 2 3
  • HE9 3 4
  • Epididymis Secretory Sperm Binding Protein Li 45e 3
  • HEL-S-45e 3
  • TMEM45C 3
  • EDDM9 3
  • Epdd1 3

External Ids for TEDDM1 Gene

Previous GeneCards Identifiers for TEDDM1 Gene

  • GC01M179100
  • GC01M180633
  • GC01M153603

Summaries for TEDDM1 Gene

GeneCards Summary for TEDDM1 Gene

TEDDM1 (Transmembrane Epididymal Protein 1) is a Protein Coding gene. An important paralog of this gene is TMEM45A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEDDM1 Gene

Genomics for TEDDM1 Gene

Regulatory Elements for TEDDM1 Gene

Enhancers for TEDDM1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F182142 1.8 FANTOM5 Ensembl ENCODE 12 +254.0 253955 7.9 PKNOX1 ATF1 ARNT WRNIP1 YY1 GATA2 ZNF143 NCOA1 REST TBX21 GLUL TEDDM1 RNU6-152P RPL18P2 RGS16 RGSL1 RNASEL ENSG00000232309 GC01M182183
GH01F182257 1.6 FANTOM5 Ensembl ENCODE 11.2 +141.3 141316 3.4 ATF1 PKNOX1 CREB3L1 FEZF1 CBX5 ELK1 GATA2 KLF13 REST CREB3 GLUL TEDDM1 RNU6-152P RPL18P2 RNASEL LOC105371641 LINC01344
GH01F182173 1.6 FANTOM5 Ensembl ENCODE 11 +225.8 225752 2.5 PKNOX1 ARNT FEZF1 GLI4 ZNF2 ZNF143 KLF7 DEK REST MIER2 GLUL TEDDM1 RNU6-152P RPL18P2 RNASEL GC01M182183 ENSG00000232309
GH01F182348 1 Ensembl ENCODE 15.5 +50.9 50866 3.1 BCOR SAP130 ZMYM3 CEBPB CEBPG THRB GATA3 ATF3 POLR2A ZNF692 TEDDM1 GLUL RNU6-152P RPL18P2 EIF1P3
GH01F182087 1.1 FANTOM5 Ensembl ENCODE 11.5 +312.5 312469 2.1 KLF1 GATA3 RFX1 ESRRA GATA2 FOS GABPA GLUL TEDDM1 RGSL1 NPL ENSG00000225982 LOC105371642
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TEDDM1 on UCSC Golden Path with GeneCards custom track

Genomic Location for TEDDM1 Gene

Chromosome:
1
Start:
182,398,117 bp from pter
End:
182,400,616 bp from pter
Size:
2,500 bases
Orientation:
Minus strand

Genomic View for TEDDM1 Gene

Genes around TEDDM1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEDDM1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEDDM1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEDDM1 Gene

Proteins for TEDDM1 Gene

  • Protein details for TEDDM1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T9Z0-TEDM1_HUMAN
    Recommended name:
    Transmembrane epididymal protein 1
    Protein Accession:
    Q5T9Z0
    Secondary Accessions:
    • Q8IVJ0

    Protein attributes for TEDDM1 Gene

    Size:
    273 amino acids
    Molecular mass:
    31315 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TEDDM1 Gene

Post-translational modifications for TEDDM1 Gene

No Post-translational modifications

Other Protein References for TEDDM1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TEDDM1 Gene

Domains & Families for TEDDM1 Gene

Protein Domains for TEDDM1 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for TEDDM1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5T9Z0

UniProtKB/Swiss-Prot:

TEDM1_HUMAN :
  • Belongs to the TMEM45 family.
Family:
  • Belongs to the TMEM45 family.
genes like me logo Genes that share domains with TEDDM1: view

No data available for Gene Families for TEDDM1 Gene

Function for TEDDM1 Gene

Phenotypes for TEDDM1 Gene

genes like me logo Genes that share phenotypes with TEDDM1: view

Animal Model Products

miRNA for TEDDM1 Gene

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TEDDM1 Gene

Localization for TEDDM1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEDDM1 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEDDM1 gene
Compartment Confidence
plasma membrane 3

Gene Ontology (GO) - Cellular Components for TEDDM1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TEDDM1: view

Pathways & Interactions for TEDDM1 Gene

SuperPathways for TEDDM1 Gene

No Data Available

Interacting Proteins for TEDDM1 Gene

Gene Ontology (GO) - Biological Process for TEDDM1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TEDDM1 Gene

Transcripts for TEDDM1 Gene

mRNA/cDNA for TEDDM1 Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(6) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for TEDDM1 Gene

Transmembrane epididymal protein 1:
Representative Sequences:

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TEDDM1 Gene

No ASD Table

Relevant External Links for TEDDM1 Gene

GeneLoc Exon Structure for
TEDDM1
ECgene alternative splicing isoforms for
TEDDM1

Expression for TEDDM1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TEDDM1 Gene

mRNA differential expression in normal tissues according to GTEx for TEDDM1 Gene

This gene is overexpressed in Testis (x7.3).

NURSA nuclear receptor signaling pathways regulating expression of TEDDM1 Gene:

TEDDM1

SOURCE GeneReport for Unigene cluster for TEDDM1 Gene:

Hs.156977
genes like me logo Genes that share expression patterns with TEDDM1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TEDDM1 Gene

Orthologs for TEDDM1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TEDDM1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC469606 34
  • 98.78 (n)
TEDDM1 35
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Gm5531 34 35
  • 81.57 (n)
Teddm1 35
  • 61 (a)
OneToMany
Teddm1b 16
rat
(Rattus norvegicus)
Mammalia LOC684709 34
  • 79.34 (n)
dog
(Canis familiaris)
Mammalia -- 35
  • 67 (a)
OneToMany
-- 35
  • 64 (a)
OneToMany
cow
(Bos Taurus)
Mammalia TEDDM1 35
  • 61 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TEDDM1 35
  • 26 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 25 (a)
OneToOne
Species where no ortholog for TEDDM1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TEDDM1 Gene

ENSEMBL:
Gene Tree for TEDDM1 (if available)
TreeFam:
Gene Tree for TEDDM1 (if available)

Paralogs for TEDDM1 Gene

Paralogs for TEDDM1 Gene

Pseudogenes.org Pseudogenes for TEDDM1 Gene

genes like me logo Genes that share paralogs with TEDDM1: view

Variants for TEDDM1 Gene

Sequence variations from dbSNP and Humsavar for TEDDM1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs10911071 -- 182,399,323(+) AATTA(A/G)AGGCT utr-variant-3-prime
rs111793307 -- 182,400,034(+) TGTTG(A/G)GAGCC reference, missense
rs111974002 -- 182,402,589(+) CATTT(-/TTTG)TTTGT upstream-variant-2KB
rs112140293 -- 182,400,413(+) TATTT(C/T)CCACA reference, missense
rs112817733 -- 182,400,035(+) GTTGG(G/T)AGCCC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for TEDDM1 Gene

Variant ID Type Subtype PubMed ID
nsv548358 CNV gain 21841781

Variation tolerance for TEDDM1 Gene

Residual Variation Intolerance Score: 42% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.59; 12.77% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEDDM1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEDDM1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEDDM1 Gene

Disorders for TEDDM1 Gene

Relevant External Links for TEDDM1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEDDM1

No disorders were found for TEDDM1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TEDDM1 Gene

Publications for TEDDM1 Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 4 64

Products for TEDDM1 Gene

Sources for TEDDM1 Gene

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