TEDDM1 Gene
protein-coding GIFtS: 35
GCID: GC01M182367
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transmembrane epididymal protein 1
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Aliases
for TEDDM1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Transmembrane Epididymal Protein 11 2 | | RP1-223H12.22 | | HE91 2 3 | | Epididymal Protein 92 | | EDDM91 2 | | Putative Membrane Protein HE92 | | Epdd11 2 | | Transmembrane Protein 45C2 | | TMEM45C1 2 | | He93 | | Human Epididymis-Specific Protein 92 3 | | |
Export aliases for TEDDM1 gene to outside databasesPrevious GC identifers: GC01M179100 GC01M180633 GC01M153603 |
Summaries
for TEDDM1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TEDDM1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004487.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TEDDM1 gene promoter:
AP-1 ATF-2 c-Jun
Other transcription factors
Search SABiosciences Chromatin IP Primers for TEDDM1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEDDM1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1q25.3 Ensembl cytogenetic band: 1q25.3 HGNC cytogenetic band: 1q25.3TEDDM1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01M182367: view genomic region
(about GC identifiers)
Start:
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182,367,252 bp from pter |
End:
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182,369,751 bp from pter |
Size:
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2,500 bases |
Orientation:
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minus strand |
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Proteins
for TEDDM1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TEDM1_HUMAN, Q5T9Z0 (See
protein sequence)Recommended Name: Transmembrane epididymal protein 1 Size: 273 amino acids; 31315 Da
Subcellular location: Membrane; Multi-pass membrane protein (Potential)
Secondary accessions: Q8IVJ0Explore the universe of human proteins at neXtProt for TEDDM1: NX_Q5T9Z0
TEDDM1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_741997.3
ENSEMBL proteins: ENSP00000356536
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016021 | integral to membrane |
IEA | -- |
TEDDM1 for ontologies About GeneDecksing
TEDDM1 Antibody Products:
Assay Products for TEDDM1: |
Protein
Domains /
Families
for TEDDM1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TEDDM1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q5T9Z0ProtoNet protein and cluster: Q5T9Z0 UniProtKB/Swiss-Prot: TEDM1_HUMAN, Q5T9Z0Similarity: Belongs to the TMEM45 family |
Function
for TEDDM1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEDDM1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEDDM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TEDDM1 (NM_172000) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEDDM1 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TEDDM1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEDDM1 |
|
Pathways & Interactions
for TEDDM1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEDDM1
|
Drugs & Compounds
for TEDDM1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TEDDM1
Search CenterWatch for drugs/clinical trials and news about TEDDM1 / TEDM1
|
Transcripts
for TEDDM1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TEDDM1 gene: NM_172000.3 Unigene Cluster for TEDDM1: Transmembrane epididymal protein 1 Hs.156977 [show with all ESTs]Unigene Representative Sequence: NM_1720001 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000367565(uc001gpe.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEDDM1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEDDM1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TEDDM1 (NM_172000) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEDDM1 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TEDDM1 |
Additional cDNA sequence: AJ515384.2 1 DOTS entry: DT.99999640 6 AceView cDNA sequences: BU570064 AA885195 BX089517 AA335545 AJ515384 NM_172000
GeneLoc Exon Structure
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Expression
for TEDDM1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TEDDM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTTATGTTTA
About this image
See TEDDM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TEDDM1
SOURCE GeneReport for Unigene cluster: Hs.156977
SABiosciences Custom PCR Arrays for TEDDM1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEDDM1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TEDDM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEDDM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEDDM1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEDDM1 |
Orthologs
for TEDDM1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
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ENSEMBL Gene Tree for TEDDM1 (if available)
TreeFam Gene Tree for TEDDM1 (if available) |
Paralogs
for TEDDM1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TEDDM1 gene
- TMEM45A2 TMEM45B2
TEDDM1 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for TEDDM1
PGOHUM00000245115 PGOHUM00000237894
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Genomic Variants
for TEDDM1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TEDDM1 (182367252 - 182369751 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TEDDM1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEDDM1 |
|
Disorders
/ Diseases
for TEDDM1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TEDDM1 for disorders About GeneDecksing
1  disease for TEDDM1: About MalaCardsepididymitis
Export disorders for TEDDM1 gene to outside databases
|
Publications
for TEDDM1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TEDDM1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TEDDM1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)2 Gregory S.G.... Bentley D.R. (2006)
- Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
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External Searches for TEDDM1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing TEDDM1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TEDDM1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TEDDM1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for TEDDM1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for TEDDM1 gene:
Search GeneIP for patents involving TEDDM1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TEDDM1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for TEDDM1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TEDDM1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEDDM1 | | | OriGene Protein Over-expression Lysate for TEDDM1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TEDDM1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEDDM1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEDDM1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TEDDM1 | | OriGene Custom Protein Services for TEDDM1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TEDDM1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEDDM1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEDDM1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEDDM1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEDDM1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEDDM1 |
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 |  |  |  | |
| | | | Search Tocris compounds for TEDDM1 |
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 | | | TEDDM1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEDDM1 |
|  |  |  | | | | Search ThermoFisher Antibodies for TEDDM1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TEDDM1 |
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