Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



TECTB Gene

protein-coding   GIFtS: 47
GCID: GC10P114033

Tectorin Beta

  See TECTB-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Tectorin Beta1 2
beta-tectorin2

External Ids:    HGNC: 117211   Entrez Gene: 69752   Ensembl: ENSG000001199137   OMIM: 6026535   UniProtKB: Q96PL23   

Export aliases for TECTB gene to outside databases

Previous GC identifers: GC10P112936 GC10P113277 GC10P114174 GC10P113708 GC10P107671


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

Entrez Gene summary for TECTB Gene:
This gene encodes a non-collagenous glycoprotein component of the tectorial membrane, which covers the auditory
hair cells in the cochlea of the inner ear. A similar protein in mouse functions in low-frequency hearing.
(provided by RefSeq, Jul 2013)

GeneCards Summary for TECTB Gene:
TECTB (tectorin beta) is a protein-coding gene. Diseases associated with TECTB include enlarged vestibular aqueduct. GO annotations related to this gene include extracellular matrix structural constituent. An important paralog of this gene is ZPLD1.

UniProtKB/Swiss-Prot: TECTB_HUMAN, Q96PL2
Function: One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial
membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts
the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to
the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential,
transducing sound into electrical signals

Gene Wiki entry for TECTB Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_030059.14  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TECTB gene promoter:
         ER-alpha   TBP   HSF1 (long)   LCR-F1   Tal-1beta   RORalpha2   Egr-4   TFIID   HSF1short   ITF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TECTB promoter sequence
   Search Chromatin IP Primers for TECTB

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TECTB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25-q26   Ensembl cytogenetic band:  10q25.2   HGNC cytogenetic band: 10q25-q26

TECTB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TECTB gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P114033:  view genomic region     (about GC identifiers)

Start:
114,043,493 bp from pter      End:
114,064,793 bp from pter
Size:
21,301 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: TECTB_HUMAN, Q96PL2 (See protein sequence)
Recommended Name: Beta-tectorin precursor  
Size: 329 amino acids; 36956 Da
Subunit: May form homomeric filament after self-association or heteromeric filament after association with
alpha-tectorin
Secondary accessions: Q5VW53

Explore the universe of human proteins at neXtProt for TECTB: NX_Q96PL2

Explore proteomics data for TECTB at MOPED

Post-translational modifications: 

  • The presence of a hydrophobic C-terminus preceded by a potential cleavage site strongly suggests that tectorins
    are synthesized as glycosylphosphatidylinositol-linked, membrane-bound precursors. Tectorins are targeted to the
    apical surface of the inner ear epithelia by the lipid and proteolytically released into the extracellular
    compartment1
  • Glycosylation2 at Asn80, Asn104, Asn116, Asn145

  • See TECTB Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_478129.1  
    ENSEMBL proteins: 
     ENSP00000358430  

    TECTB Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    Browse OriGene Protein Over-expression Lysates
    OriGene Custom MassSpec
    OriGene Custom Protein Services for TECTB
    GenScript Custom Purified and Recombinant Proteins Services for TECTB
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for TECTB 

     
    antibodies-online proteins for TECTB (3 products) 

     
    antibodies-online peptides for TECTB

    TECTB Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for TECTB
    Abcam antibodies for TECTB
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for TECTB
    antibodies-online antibodies for TECTB (21 products) 

    TECTB Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TECTB
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TECTB
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for TECTB 
    antibodies-online kits for TECTB (6 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR017977 ZP_dom_CS
     IPR001507 ZP_dom

    Graphical View of Domain Structure for InterPro Entry Q96PL2

    ProtoNet protein and cluster: Q96PL2

    UniProtKB/Swiss-Prot: TECTB_HUMAN, Q96PL2
    Domain: Zona pellucida domain may enable to form filaments
    Similarity: Contains 1 ZP domain


    Find genes that share domains with TECTB           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TECTB_HUMAN, Q96PL2
    Function: One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial
    membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts
    the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to
    the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential,
    transducing sound into electrical signals

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005201extracellular matrix structural constituent ----
         
    Find genes that share ontologies with TECTB           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tectb):
     hearing/vestibular/ear  nervous system 

    Find genes that share phenotypes with TECTB           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Tectbtm1Gpr for TECTB

       genOway: Develop your customized and physiologically relevant rodent model for TECTB

    miRNA
    Products:
        
    miRTarBase miRNAs that target TECTB:
    hsa-mir-335-5p (MIRT018143)

    Block miRNA regulation of human, mouse, rat TECTB using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TECTB
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TECTB
    Predesigned siRNA for gene silencing in human, mouse, rat TECTB

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TECTB

    Clone
    Products:
         
    OriGene clones in human, mouse for TECTB (see all 5)
    OriGene ORF clones in mouse, rat for TECTB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TECTB (NM_058222)
    Sino Biological Human cDNA Clone for TECTB
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TECTB
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TECTB

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TECTB
    Browse ESI BIO Cell Lines and PureStem Progenitors for TECTB 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TECTB


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from UniProtKB/Swiss-Prot
    TECTB_HUMAN, Q96PL2: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side (Probable). Secreted,
    extracellular space, extracellular matrix. Note=Found in the non-collagenous matrix of the tectorial membrane (By
    similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular5
    plasma membrane5
    golgi apparatus1
    lysosome1
    mitochondrion1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005578proteinaceous extracellular matrix IEA--
    GO:0005886plasma membrane IEA--
    GO:0031225anchored component of membrane IEA--

    Find genes that share ontologies with TECTB           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TECTB
    Interactions:

        Search GeneGlobe Interaction Network for TECTB

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TECTB



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for TECTB gene: 
    NM_058222.2  

    Unigene Cluster for TECTB:

    Tectorin beta
    Hs.348615  [show with all ESTs]
    Unigene Representative Sequence: BC113497
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369422(uc001kzr.1) ENST00000494328
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TECTB using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate TECTB
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TECTB
    Predesigned siRNA for gene silencing in human, mouse, rat TECTB
    Clone
    Products:
         
    OriGene clones in human, mouse for TECTB (see all 5)
    OriGene ORF clones in mouse, rat for TECTB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TECTB (NM_058222)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TECTB
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TECTB
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TECTB
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TECTB
      QuantiTect SYBR Green Assays in human, mouse, rat TECTB
      QuantiFast Probe-based Assays in human, mouse, rat TECTB

    Additional mRNA sequence: 

    AF312827.1 BC113497.1 BC113499.1 

    2 DOTS entries:

    DT.97788079  DT.97814614 

    4 AceView cDNA sequences:

    AF312827 NM_058222 BQ185496 BQ187858 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    TECTB expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGAATGGGAG
    TECTB Expression
    About this image

    TECTB Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TECTB Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.348615
        Custom PCR Arrays for TECTB
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TECTB
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TECTB
    QuantiTect SYBR Green Assays in human, mouse, rat TECTB
    QuantiFast Probe-based Assays in human, mouse, rat TECTB
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TECTB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for TECTB gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tectb1 , 5 tectorin beta1, 5 88.04(n)1
    94.22(a)1
      19 (51.13 cM)5
    216841  NM_009348.31  NP_033374.21 
     551807335 
    chicken
    (Gallus gallus)
    Aves TECTB1 tectorin beta 74.19(n)
    73.78(a)
      396320  NM_205363.1  NP_990694.1 
    lizard
    (Anolis carolinensis)
    Reptilia TECTB6
    tectorin beta
    71(a)
    1 ↔ 1
    GL343204.1(2077739-2103366)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.57072 Transcribed sequence with moderate similarity to protein more 75.8(n)    BX707514.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tectb1 tectorin beta 57.38(n)
    56.04(a)
      494051  NM_001008594.1  NP_001008594.1 


    ENSEMBL Gene Tree for TECTB (if available)
    TreeFam Gene Tree for TECTB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for TECTB gene
    ZPLD12  

    Find genes that share paralogs with TECTB           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for TECTB (see all 597)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1486701371,2
    --114041595(+) GATGAC/TGCTGG 1 -- us2k10--------
    rs1842349311,2
    --114041704(+) AGGGAA/GGGGAA 1 -- us2k10--------
    rs1885684471,2
    --114041717(+) TCACAC/TACCAG 1 -- us2k10--------
    rs1809835231,2
    C--114041778(+) CCTAAC/TGTAGA 1 -- us2k10--------
    rs1852636801,2
    --114041845(+) CCTGCA/TCGTTC 1 -- us2k10--------
    rs1421472911,2
    C--114041866(+) CCCCAC/GAACTT 1 -- us2k10--------
    rs1512769721,2
    --114041875(+) TTAAAA/GTATAA 1 -- us2k10--------
    rs1996485481,2
    --114041941(+) TGTTT-/AAAAAA 1 -- us2k10--------
    rs728196291,2
    C,F--114041948(+) AAAAAT/ATTTTT 1 -- us2k15Minor allele frequency- A:0.24WA CSA NA EA 362
    rs1995700911,2
    C--114041993(+) TTGTT-/CATCAT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TECTB (114043493 - 114064793 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for TECTB:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv526495CNV Loss19592680
    nsv510233CNV Loss20534489
    nsv471669CNV Gain15918152
    nsv831989CNV Gain17160897
    nsv7211OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TECTB
    DNA2.0 Custom Variant and Variant Library Synthesis for TECTB

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 602653    OMIM disorders: --

    1 disease for TECTB:    
    About MalaCards
    enlarged vestibular aqueduct

    3 diseases from the University of Copenhagen DISEASES database for TECTB:
    Enlarged vestibular aqueduct     Sensorineural hearing loss     Nonsyndromic deafness

    Find genes that share disorders with TECTB           About GenesLikeMe

    Genetic Association Database (GAD): TECTB
    Human Genome Epidemiology (HuGE) Navigator: TECTB (2 documents)

    Export disorders for TECTB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for TECTB gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with TECTB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    2. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    5. The mouse tectorins. Modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system. (PubMed id 9079715)1, 3 Legan P.K....Richardson G.P. (J. Biol. Chem. 1997)
    6. Loss of mammal-specific tectorial membrane component carcinoembryonic antigen cell adhesion molecule 16 (CEACAM16) leads to hearing impairment at low and high frequencies. (PubMed id 22544735)1 Kammerer R....Zimmermann W. (J. Biol. Chem. 2012)
    7. Identification of polymorphisms in ultraconserved elements associated with clinical outcomes in locally advanced colorectal adenocarcinoma. (PubMed id 22673945)1 Lin M....Wu X. (Cancer 2012)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    9. Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening. (PubMed id 7829101)1 Robertson N.G....Morton C.C. (Genomics 1994)
    10. (PubMed id )2 

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 6975 HGNC: 11721 AceView: TECTB Ensembl:ENSG00000119913 euGenes: HUgn6975
    ECgene: TECTB H-InvDB: TECTB

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for TECTB Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for TECTB gene:
    Search GeneIP for patents involving TECTB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for TECTB  
     Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for TECTB  
     OriGene qSTAR qPCR primer pairs in human, mouse for TECTB   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for TECTB   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for TECTB   OriGene Custom Protein Services for TECTB  

     
     
     Block miRNA regulation of human, mouse, rat TECTB using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TECTB
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TECTB Predesigned siRNA for gene silencing in human, mouse, rat TECTB
     QuantiFast Probe-based Assays in human, mouse, rat TECTB QuantiTect SYBR Green Assays in human, mouse, rat TECTB
     Custom PCR Arrays for TECTB Search Chromatin IP Primers for TECTB
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TECTB  Search GeneGlobe Interaction Network for TECTB
     Regulatory tfbs in TECTB promoter
     GenScript Custom Purified and Recombinant Proteins Services for TECTB GenScript cDNA clones with any tag delivered in your preferred vector for TECTB
     GenScript Custom Assay Services for TECTB GenScript Custom overexpressing Cell Line Services for TECTB
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for TECTB
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for TECTB
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Biologicals
     Novus Tissue Slides
     Antibodies for TECTB
     See all of Abcam's Antibodies, Kits and Proteins for TECTB
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for TECTB
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TECTB
     Browse SwitchGear 3'UTR luciferase reporter plasmids for TECTB
     SwitchGear Promoter luciferase reporter plasmids for TECTB
     ThermoFisher Antibodies for TECTB
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TECTB
     Browse compounds at ApexBio
     Search Addgene for plasmids for TECTB
      Search eBioscience for proteins for TECTB
      Search eBioscience for elisas for TECTB
      eBioscience FlowRNA Probe Sets
     genOway: Develop your customized and physiologically relevant rodent model for TECTB
     antibodies-online antibodies for TECTB (21 products)
     antibodies-online kits for TECTB (6 products)
     antibodies-online peptides for TECTB
     antibodies-online proteins for TECTB (3 products)
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014 , 7 Oct 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      TECTB gene at Home site.
    Version: 3.12.258 10 Dec 2014
    hostname: 356980-web2.xennexinc.com index build: 128 solr: 1.4