External Ids for TECTB Gene
Previous GeneCards Identifiers for TECTB Gene
This gene encodes a non-collagenous glycoprotein component of the tectorial membrane, which covers the auditory hair cells in the cochlea of the inner ear. A similar protein in mouse functions in low-frequency hearing. [provided by RefSeq, Jul 2013]
GeneCards Summary for TECTB Gene
TECTB (Tectorin Beta) is a Protein Coding gene. Diseases associated with TECTB include Deafness, Autosomal Recessive 21 and Usher Syndrome, Type 1B. Among its related pathways are Post-translational modification- synthesis of GPI-anchored proteins and Metabolism of proteins. An important paralog of this gene is ZPLD1.
UniProtKB/Swiss-Prot for TECTB Gene
One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair-cell membrane potential, transducing sound into electrical signals.