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TECPR2 Gene

protein-coding   GIFtS: 45
GCID: GC14P102829

Tectonin Beta-Propeller Repeat Containing 2

(Previous name: KIAA0329)
(Previous symbol: KIAA0329)
  See TECPR2-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tectonin Beta-Propeller Repeat Containing 21 2
KIAA03291 2 3 5
SPG492 5
Tectonin Beta-Propeller Repeat-Containing Protein 22
KIAA02973
WD Repeat-Containing Protein KIAA0329/KIAA02973

External Ids:    HGNC: 199571   Entrez Gene: 98952   Ensembl: ENSG000001966637   OMIM: 6150005   UniProtKB: O150403   

Export aliases for TECPR2 gene to outside databases

Previous GC identifers: GC14P101901 GC14P083006


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TECPR2 Gene:
TECPR2 (tectonin beta-propeller repeat containing 2) is a protein-coding gene. Diseases associated with TECPR2 include spastic paraplegia 49, autosomal recessive. An important paralog of this gene is HPS5.

UniProtKB/Swiss-Prot: TCPR2_HUMAN, O15040
Function: Probably plays a role as positive regulator of autophagy




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000014.8  NT_026437.13  NC_018925.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TECPR2 gene promoter:
         SRF   USF1   SRF (504 AA)   USF2   Olf-1   USF-1:USF-2   HEN1   PPAR-gamma1   USF-1   PPAR-gamma2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TECPR2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TECPR2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q32.31   Ensembl cytogenetic band:  14q32.31   HGNC cytogenetic band: 14q32.33

TECPR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TECPR2 gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14P102829:  view genomic region     (about GC identifiers)

Start:
102,829,300 bp from pter      End:
102,968,818 bp from pter
Size:
139,519 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TCPR2_HUMAN, O15040 (See protein sequence)
Recommended Name: Tectonin beta-propeller repeat-containing protein 2  
Size: 1411 amino acids; 153848 Da
Subunit: Interacts with the ATG8 family members GABARAP, GABARAPL1, GABARAPL2, MAP1LC3B and MAP1LC3C
Sequence caution: Sequence=BAA20787.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: A5PKY3 A6NFY9 A7E2X3 H0YMM9 Q9UEG6
Alternative splicing: 2 isoforms:  O15040-1   O15040-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TECPR2: NX_O15040

Explore proteomics data for TECPR2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TECPR2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001166102.1  NP_055659.2  

    ENSEMBL proteins: 
     ENSP00000352510   ENSP00000453671  

    TECPR2 Human Recombinant Protein Products:

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    Browse OriGene Protein Over-expression Lysates
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TECPR2

     
    Search eBioscience for Proteins for TECPR2 

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    Abcam antibodies for TECPR2
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    TECPR2 Assay Products:

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    Cloud-Clone Corp. ELISAs for TECPR2
    Cloud-Clone Corp. CLIAs for TECPR2
    Search eBioscience for ELISAs for TECPR2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    5 InterPro protein domains:
     IPR006624 Beta-propeller_rpt_TECPR
     IPR001680 WD40_repeat
     IPR009091 RCC1/BLIP-II
     IPR017986 WD40_repeat_dom
     IPR015943 WD40/YVTN_repeat-like_dom

    Graphical View of Domain Structure for InterPro Entry O15040

    ProtoNet protein and cluster: O15040

    2 Blocks protein domains:
    IPB001680 G-protein beta WD-40 repeat signature
    IPB006624 Beta-propeller repeat TECPR


    UniProtKB/Swiss-Prot: TCPR2_HUMAN, O15040
    Similarity: Belongs to the WD repeat KIAA0329 family
    Similarity: Contains 6 TECPR repeats
    Similarity: Contains 3 WD repeats


    Find genes that share domains with TECPR2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TCPR2_HUMAN, O15040
    Function: Probably plays a role as positive regulator of autophagy

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with TECPR2           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TECPR2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TECPR2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TECPR2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TECPR2

    miRNA
    Products:
        
    miRTarBase miRNAs that target TECPR2:
    hsa-mir-92a-3p (MIRT049520)

    Block miRNA regulation of human, mouse, rat TECPR2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TECPR2 (see all 39):
    hsa-let-7d hsa-miR-25 hsa-let-7g hsa-miR-374c hsa-miR-124 hsa-miR-4325 hsa-let-7a hsa-miR-330-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TECPR2

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    GenScript: all cDNA clones in your preferred vector (see all 2): TECPR2 (NM_014844)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TECPR2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TECPR2

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TECPR2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TECPR2
    Interactions:

        Search GeneGlobe Interaction Network for TECPR2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5 Interacting proteins for TECPR2 (O150401, 3 ENSP000003525104) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAP1LC3CQ9BXW41, 3, ENSP000003497854EBI-2946991,EBI-2603996 I2D: score=1 STRING: ENSP00000349785
    GABARAPO951661, 3EBI-2946991,EBI-712001 I2D: score=3 
    GABARAPL1Q9H0R81, 3EBI-2946991,EBI-746969 I2D: score=1 
    GABARAPL2P605201, 3EBI-2946991,EBI-720116 I2D: score=1 
    MAP1LC3BQ9GZQ83I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006914autophagy IEA--
    GO:0008219cell death IEA--

    Find genes that share ontologies with TECPR2           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TECPR2 (TCPR2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TECPR2 gene (2 alternative transcripts): 
    NM_001172631.1  NM_014844.3  

    Unigene Cluster for TECPR2:

    Tectonin beta-propeller repeat containing 2
    Hs.195667  [show with all ESTs]
    Unigene Representative Sequence: NM_014844
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000359520(uc010txw.2 uc001ylw.2 uc010txx.2) ENST00000561228
    ENST00000558678(uc010awl.3) ENST00000560060 ENST00000557786 ENST00000561099
    ENST00000559124
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TECPR2 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate TECPR2 (see all 39):
    hsa-let-7d hsa-miR-25 hsa-let-7g hsa-miR-374c hsa-miR-124 hsa-miR-4325 hsa-let-7a hsa-miR-330-3p
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TECPR2
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    GenScript: all cDNA clones in your preferred vector (see all 2): TECPR2 (NM_014844)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TECPR2
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TECPR2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TECPR2
      QuantiTect SYBR Green Assays in human, mouse, rat TECPR2
      QuantiFast Probe-based Assays in human, mouse, rat TECPR2

    Additional mRNA sequence: 

    AB002295.1 AB002327.1 AK127721.1 AK296395.1 AK299690.1 BC030791.1 BC136647.1 BC142667.1 
    BC142715.1 BC151230.1 

    7 DOTS entries:

    DT.315306  DT.101982198  DT.108044  DT.97826685  DT.120750215  DT.120750253  DT.91707976 

    Selected AceView cDNA sequences (see all 129):

    Z28886 BE905063 AW271524 CF130082 AI753137 AA468525 AW054894 BU632244 
    AI914649 AW168152 AA972038 BQ773045 CF553053 BQ023338 AI244826 AI753372 
    BQ025571 T64533 AB002295 C01547 AW006393 AI870614 AI026790 BM709324 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TECPR2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TECPR2 Expression
    About this image

    TECPR2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TECPR2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.195667

    UniProtKB/Swiss-Prot: TCPR2_HUMAN, O15040
    Tissue specificity: Detected in skin fibroblast (at protein level)

        Custom PCR Arrays for TECPR2
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TECPR2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TECPR2 gene from Selected species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tecpr21 , 5 tectonin beta-propeller repeat containing 21, 5 83.03(n)1
    82.7(a)1
      12 (60.86 cM)5
    1048591  NM_001081057.21  NP_001074526.11 
     1108892645 
    chicken
    (Gallus gallus)
    Aves TECPR21 tectonin beta-propeller repeat containing 2 70.36(n)
    73.5(a)
      423468  XM_421376.4  XP_421376.4 
    lizard
    (Anolis carolinensis)
    Reptilia TECPR26
    tectonin beta-propeller repeat containing 2
    62(a)
    1 ↔ 1
    GL343232.1(1755039-1800065)
    African clawed frog
    (Xenopus laevis)
    Amphibia BU906194.12   -- 76.06(n)    BU906194.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.253302 Transcribed sequence with weak similarity to protein more 73.58(n)    AL924656.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG111416
    --
    23(a)
    1 ↔ 1
    2R(3347936-3350900)


    ENSEMBL Gene Tree for TECPR2 (if available)
    TreeFam Gene Tree for TECPR2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TECPR2 gene
    HPS52  

    Find genes that share paralogs with TECPR2           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TECPR2 (see all 2870)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1113717111,2
    C,F--102831336(+) GCTGTC/TACTCA 2 -- int11Minor allele frequency- T:0.50CSA 2
    rs37595611,2
    C,F--102831348(+) GATGCA/GTGTTC 2 -- int13Minor allele frequency- G:0.08WA NA EA 358
    rs1430813371,2
    --102831368(+) TGAATA/GTATTC 2 -- int10--------
    rs1907374871,2
    --102831543(+) CACAAA/GGTATA 2 -- int10--------
    rs1830276851,2
    --102831695(+) ATGAAG/TGCTTC 2 -- int10--------
    rs1131740581,2
    C,F--102831731(+) AGGGCA/GCATGT 2 -- int11Minor allele frequency- G:0.03NA 120
    rs284138891,2
    C,F--102831756(+) GAGTGG/AAAAGG 2 -- int16Minor allele frequency- A:0.18NA WA CSA 246
    rs1386142721,2
    --102831784(+) ACATAC/GAGGTT 2 -- int10--------
    rs1147542971,2
    C,F--102831791(+) GGTTAT/CGGTGT 2 -- int11Minor allele frequency- C:0.01WA 118
    rs37595621,2
    C,F,A,H--102831817(+) TGGAAA/GGCTGA 2 -- int15Minor allele frequency- G:0.16NA WA EA 364

    HapMap Linkage Disequilibrium report for TECPR2 (102829300 - 102968818 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for TECPR2 (see all 12):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2676040CNV Deletion23128226
    esv2671371CNV Deletion23128226
    esv2670585CNV Deletion23128226
    esv2749150CNV Deletion23290073
    nsv832880CNV Loss17160897
    nsv902255CNV Loss21882294
    nsv522878CNV Loss19592680
    dgv1984n71CNV Loss21882294
    nsv470671CNV Gain18288195
    dgv263n27CNV Gain19166990

    Human Gene Mutation Database (HGMD): TECPR2
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TECPR2
    DNA2.0 Custom Variant and Variant Library Synthesis for TECPR2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 615000   
    OMIM disorders: 615031  
    UniProtKB/Swiss-Prot: TCPR2_HUMAN, O15040
  • Spastic paraplegia 49, autosomal recessive (SPG49) [MIM:615031]: A form of spastic paraplegia, a
    neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower
    limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include
    difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking.
    In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness
    may spread to other parts of the body. Complicated forms are characterized by the addition of such neurological
    features as spastic quadriparesis, seizures, dementia, amyotrophy, extrapyramidal disturbance, cerebral or
    cerebellar atrophy, optic atrophy, and peripheral neuropathy, as well as by extra neurological manifestations
    such as dysmorphism, albinism, retinitis pigmentosa, deafness, dementia, amyotrophy and ichthyosis. SPG49 is
    characterized by delayed psychomotor development, mental retardation, and onset of spastic paraplegia in the
    first decade. Affected individuals also have dysmorphic features, thin corpus callosum on brain imaging, and
    episodes of central apnea, which may be fatal. Note=The disease is caused by mutations affecting the gene
    represented in this entry

  • 1 disease for TECPR2:    
    About MalaCards
    spastic paraplegia 49, autosomal recessive


    Find genes that share disorders with TECPR2           About GenesLikeMe


    Export disorders for TECPR2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TECPR2 gene integrated from 10 sources:
    (articles sorted by number of sources associating them with TECPR2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. (PubMed id 9205841)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1997)
    2. Mutation in TECPR2 reveals a role for autophagy in hereditary spastic paraparesis. (PubMed id 23176824)1, 2 Oz-Levi D....Lancet D. (Am. J. Hum. Genet. 2012)
    3. Network organization of the human autophagy system. (PubMed id 20562859)1, 2 Behrends C....Harper J.W. (Nature 2010)
    4. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    5. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. The DNA sequence and analysis of human chromosome 14. (PubMed id 12508121)2 Heilig R.... Weissenbach J. (Nature 2003)
    8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9895 HGNC: 19957 AceView: KIAA0329 Ensembl:ENSG00000196663 euGenes: HUgn9895
    ECgene: TECPR2 H-InvDB: TECPR2

    (According to HUGE)
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    HUGE: KIAA0329 KIAA0297

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TECPR2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TECPR2 gene:
    Search GeneIP for patents involving TECPR2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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