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TECPR1 Gene

protein-coding   GIFtS: 48
GCID: GC07M097843

Tectonin Beta-Propeller Repeat Containing 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tectonin Beta-Propeller Repeat Containing 11 2
KIAA13583 5
Tectonin Beta-Propeller Repeat-Containing Protein 12

External Ids:    HGNC: 222141   Entrez Gene: 258512   Ensembl: ENSG000002053567   OMIM: 6147815   UniProtKB: Q7Z6L13   

Export aliases for TECPR1 gene to outside databases

Previous GC identifers: GC07M097684 GC07M092446


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TECPR1 Gene:
This gene encodes a tethering factor involved in autophagy. The encoded protein is found at autolysosomes, and is
involved in targeting protein aggregates, damaged mitochondria, and bacterial pathogens for autophagy (provided
by RefSeq, Nov 2012)

GeneCards Summary for TECPR1 Gene:
TECPR1 (tectonin beta-propeller repeat containing 1) is a protein-coding gene. GO annotations related to this gene include phosphatidylinositol-3-phosphate binding.

UniProtKB/Swiss-Prot: TCPR1_HUMAN, Q7Z6L1
Function: Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the
autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and
phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in
selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure
biogenesis and maturation




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000007.13  NT_007933.16  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TECPR1 gene promoter:
         TBP   NCX/Ncx   CUTL1   Arnt   Max   PPAR-gamma1   FAC1   TFIID   PPAR-gamma2   c-Myc   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for TECPR1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TECPR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q21.3   Ensembl cytogenetic band:  7q21.3   HGNC cytogenetic band: 7q21.3

TECPR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TECPR1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M097843:  view genomic region     (about GC identifiers)

Start:
97,843,936 bp from pter      End:
97,881,563 bp from pter
Size:
37,628 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 97,170,912-97,206,345     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TCPR1_HUMAN, Q7Z6L1 (See protein sequence)
Recommended Name: Tectonin beta-propeller repeat-containing protein 1  
Size: 1165 amino acids; 129696 Da
Subunit: Interacts with ATG5; the interaction is direct. Interacts with WIPI2. Interacts with the ATG5-ATG12
conjugate, the interaction is however mutually exclusive with ATG16, since it does not interact with
ATG12-ATG5-ATG16 complex
Secondary accessions: A8KAD1 B3KPZ1 C9J024 F5GX57 Q96EB0 Q9P2I9 Q9UFR6
Alternative splicing: 4 isoforms:  Q7Z6L1-1   Q7Z6L1-2   Q7Z6L1-3   Q7Z6L1-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TECPR1: NX_Q7Z6L1

Explore proteomics data for TECPR1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TECPR1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_056210.1  
    ENSEMBL proteins: 
     ENSP00000404923   ENSP00000407471   ENSP00000412675   ENSP00000396076   ENSP00000369121  
     ENSP00000441121  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    5 InterPro protein domains:
     IPR006624 Beta-propeller_rpt_TECPR
     IPR006614 Peroxin/Ferlin
     IPR010482 Peroxin/Dysferlin
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry Q7Z6L1

    ProtoNet protein and cluster: Q7Z6L1

    3 Blocks protein domains:
    IPB001849 Pleckstrin-like
    IPB006614 Dysferlin
    IPB006624 Beta-propeller repeat TECPR


    UniProtKB/Swiss-Prot: TCPR1_HUMAN, Q7Z6L1
    Domain: The PH domain mediates the binding to phosphatidylinositol-3-phosphate (PtdIns(3)P). While full-length
    protein is unable to bind PtdIns(3)P in vitro, it is assumed that the binding to the ATG5-ATG12 conjugate exposes
    the PH domain, allowing the association with PtdIns(3)P (PubMed:22342342)
    Similarity: Belongs to the TECPR1 family
    Similarity: Contains 1 PH domain
    Similarity: Contains 9 TECPR repeats


    Find genes that share domains with TECPR1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TCPR1_HUMAN, Q7Z6L1
    Function: Tethering factor involved in autophagy. Involved in autophagosome maturation by promoting the
    autophagosome fusion with lysosomes: acts by associating with both the ATG5-ATG12 conjugate and
    phosphatidylinositol-3-phosphate (PtdIns(3)P) present at the surface of autophagosomes. Also involved in
    selective autophagy against bacterial pathogens, by being required for phagophore/preautophagosomal structure
    biogenesis and maturation

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0032266phosphatidylinositol-3-phosphate binding IDA--
         
    Find genes that share ontologies with TECPR1           About GenesLikeMe


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tecpr1):
     cellular  immune system 

    Find genes that share phenotypes with TECPR1           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Tecpr1tm1Chsa for TECPR1

       genOway: Develop your customized and physiologically relevant rodent model for TECPR1

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    miRTarBase miRNAs that target TECPR1:
    hsa-mir-335-5p (MIRT018009)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TCPR1_HUMAN, Q7Z6L1: Cytoplasmic vesicle, autophagosome membrane. Lysosome membrane. Note=Localizes to Lysosome
    membranes, and binds PtdIns(3)P at the surface of autophagosome. Localizes to autolysosomes, a vesicle formed by
    the fusion between autophagosomes and lysosomes
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    lysosome5
    vacuole5
    cytosol2
    nucleus2
    plasma membrane2
    extracellular1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000421autophagic vacuole membrane IDA--
    GO:0005765lysosomal membrane IDA--
    GO:0016021integral component of membrane IEA--
    GO:0031410cytoplasmic vesicle IEA--

    Find genes that share ontologies with TECPR1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TECPR1
    Interactions:

        Search GeneGlobe Interaction Network for TECPR1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 12)

    Selected Interacting proteins for TECPR1 (Q7Z6L11, 3 ENSP000004049234) via UniProtKB, MINT, STRING, and/or I2D (see all 256)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000212866P081073I2D: score=1 
    ENSG00000215328P081073I2D: score=1 
    ENSG00000224501P081073I2D: score=1 
    ENSG00000231555P081073I2D: score=1 
    ENSG00000232804P081073I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000046autophagic vacuole fusion IMP--
    GO:0006914autophagy IDA--

    Find genes that share ontologies with TECPR1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TECPR1 (TCPR1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TECPR1 gene: 
    NM_015395.2  

    Unigene Cluster for TECPR1:

    Tectonin beta-propeller repeat containing 1
    Hs.592281  [show with all ESTs]
    Unigene Representative Sequence: NM_015395
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 19):
    ENST00000447648(uc003upg.3) ENST00000490842 ENST00000463402 ENST00000485716
    ENST00000462511 ENST00000474915 ENST00000479975 ENST00000476659 ENST00000479911
    ENST00000483740 ENST00000471397 ENST00000463648 ENST00000472845 ENST00000423128
    ENST00000415086 ENST00000420697 ENST00000488667 ENST00000379795
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    Additional mRNA sequence: 

    AB037779.1 AK027072.1 AK057048.1 AK057618.1 AK075074.1 AK292996.1 AL117495.1 BC012529.2 
    BC053591.1 

    10 DOTS entries:

    DT.108826  DT.100752287  DT.100721618  DT.100752285  DT.95139381  DT.121050234  DT.121050257  DT.121050356 
    DT.99949757  DT.121050263 

    Selected AceView cDNA sequences (see all 128):

    BM910478 BC012529 NM_015395 BM452283 BM662816 AB037779 BQ956423 AW160792 
    BX954629 BQ448449 AI632431 AI420450 AW272594 BM677431 BU161142 BC053591 
    CB266686 AI871183 AI969609 AI129711 CD514435 AK027072 BU615847 BG828845 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TECPR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGGTGAGGC
    TECPR1 Expression
    About this image


    TECPR1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Thalamus
     
     Neural Tube (Nervous System)
             Metencephalon
     
     Spinal Cord (Nervous System)
    TECPR1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TECPR1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.592281
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TECPR1 gene from Selected species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tecpr11 , 5 tectonin beta-propeller repeat containing 11, 5 84.7(n)1
    87.17(a)1
      5 (83.07 cM)5
    703811  NM_027410.11  NP_081686.11 
     1441944425 
    chicken
    (Gallus gallus)
    Aves TECPR11 tectonin beta-propeller repeat containing 1 71.08(n)
    74.57(a)
      416436  XM_004945102.1  XP_004945159.1 
    lizard
    (Anolis carolinensis)
    Reptilia TECPR16
    tectonin beta-propeller repeat containing 1
    67(a)
    1 ↔ 1
    GL344247.1(30071-50738)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.99122 Xenopus laevis transcribed sequence with moderate similarity more 75.56(n)    BX853186.1 
    zebrafish
    (Danio rerio)
    Actinopterygii tecpr1a1 tectonin beta-propeller repeat containing 1a 66.18(n)
    68.64(a)
      556500  XM_003199588.2  XP_003199636.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta Pex231 Peroxin 23 52.43(n)
    42.08(a)
      40229  NM_168841.2  NP_730508.1 
    worm
    (Caenorhabditis elegans)
    Secernentea T01H3.26
    Protein T01H3.2 (T01H3.2) mRNA, complete cds
    23(a)
    1 ↔ 1
    II(7874232-7877994) WBGene00011348


    ENSEMBL Gene Tree for TECPR1 (if available)
    TreeFam Gene Tree for TECPR1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TECPR1 (see all 1004)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs789926791,2
    C--97844328(+) TCCCTA/TGGCCC 1 -- ds50010--------
    rs731511681,2
    C,F--97844411(+) GGTCCC/TTCAAG 1 -- ds50011Minor allele frequency- T:0.05NA 120
    rs1136569131,2
    C,F--97844454(+) ATGCCG/ATTCCT 1 -- ds50011Minor allele frequency- A:0.50CSA 2
    rs1502634391,2
    --97844481(+) CATCCC/TCCGGG 1 -- ds50010--------
    rs1379103131,2
    C--97844509(+) CCCCCA/GACAGA 1 -- ds50010--------
    rs31481,2
    C,F,O,A,H--97844578(-) ACAATC/TGCGGT 1 -- ds500131Minor allele frequency- T:0.16EA MN NS NA CSA WA 7778
    rs1494471771,2
    --97844610(+) GGAGCC/TGAACG 1 -- ds50010--------
    rs1459370501,2
    --97844619(+) CGGCCC/TGTGCC 1 -- ds50010--------
    rs1398912561,2
    --97844754(+) CAGCAA/GTGTCT 1 -- ds50010--------
    rs1908070051,2
    --97844770(+) AGGCAC/TACGGG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TECPR1 (97843936 - 97881563 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for TECPR1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv512916CNV Insertion21212237
    nsv888760CNV Loss21882294
    nsv831066CNV Loss17160897
    nsv831067CNV Loss17160897
    nsv888762CNV Loss21882294
    nsv525934CNV Loss19592680
    nsv888763CNV Loss21882294
    nsv888765CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614781    OMIM disorders: --


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    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TECPR1 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with TECPR1)
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    world of online information

    1. A mammalian autophagosome maturation mechanism mediated by TECPR1 and the Atg12-Atg5 conjugate. (PubMed id 22342342)1, 2 Chen D.... Zhong Q. (Mol. Cell 2012)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
    4. Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10718198)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    5. A Tecpr1-dependent selective autophagy pathway targets bacterial pathogens. (PubMed id 21575909)2 Ogawa M....Sasakawa C. (Cell Host Microbe 2011)
    6. The role of Tecpr1 in selective autophagy as a cargo receptor. (PubMed id 21795850)1 Ogawa M. and Sasakawa C. (Autophagy 2011)
    7. Network organization of the human autophagy system. (PubMed id 20562859)1 Behrends C....Harper J.W. (Nature 2010)
    8. A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)2 Dephoure N.... Gygi S.P. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    9. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    OMIM
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 25851 HGNC: 22214 AceView: DKFZP434B0335 Ensembl:ENSG00000205356 euGenes: HUgn25851
    ECgene: TECPR1 H-InvDB: TECPR1

    (According to HUGE)
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    HUGE: KIAA1358

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TECPR1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TECPR1 gene:
    Search GeneIP for patents involving TECPR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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