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Aliases for TEC Gene

Aliases for TEC Gene

  • Tec Protein Tyrosine Kinase 2 3 5
  • EC 2.7.10.2 4 58
  • PSCTK4 3 4
  • Tyrosine-Protein Kinase Tec 3
  • EC 2.7.10 58

External Ids for TEC Gene

Previous GeneCards Identifiers for TEC Gene

  • GC04M048214
  • GC04M048447
  • GC04M047987
  • GC04M048053
  • GC04M047978
  • GC04M047832
  • GC04M047457

Summaries for TEC Gene

Entrez Gene Summary for TEC Gene

  • The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq, Jul 2008]

GeneCards Summary for TEC Gene

TEC (Tec Protein Tyrosine Kinase) is a Protein Coding gene. Diseases associated with TEC include Transient Erythroblastopenia Of Childhood. Among its related pathways are RET signaling and Development EPO-induced Jak-STAT pathway. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is ITK.

UniProtKB/Swiss-Prot for TEC Gene

  • Non-receptor tyrosine kinase that contributes to signaling from many receptors and participates as a signal transducer in multiple downstream pathways, including regulation of the actin cytoskeleton. Plays a redundant role to ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. Required for TCR-dependent IL2 gene induction. Phosphorylates DOK1, one CD28-specific substrate, and contributes to CD28-signaling. Mediates signals that negatively regulate IL2RA expression induced by TCR cross-linking. Plays a redundant role to BTK in BCR-signaling for B-cell development and activation, especially by phosphorylating STAP1, a BCR-signaling protein. Required in mast cells for efficient cytokine production. Involved in both growth and differentiation mechanisms of myeloid cells through activation by the granulocyte colony-stimulating factor CSF3, a critical cytokine to promoting the growth, differentiation, and functional activation of myeloid cells. Participates in platelet signaling downstream of integrin activation. Cooperates with JAK2 through reciprocal phosphorylation to mediate cytokine-driven activation of FOS transcription. GRB10, a negative modifier of the FOS activation pathway, is another substrate of TEC. TEC is involved in G protein-coupled receptor- and integrin-mediated signalings in blood platelets. Plays a role in hepatocyte proliferation and liver regeneration and is involved in HGF-induced ERK signaling pathway. TEC regulates also FGF2 unconventional secretion (endoplasmic reticulum (ER)/Golgi-independent mechanism) under various physiological conditions through phosphorylation of FGF2 Tyr-215. May also be involved in the regulation of osteoclast differentiation.

Gene Wiki entry for TEC Gene

Additional gene information for TEC Gene

No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TEC Gene

Genomics for TEC Gene

Regulatory Elements for TEC Gene

Enhancers for TEC Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04H048242 0.9 dbSUPER 27.1 +26.5 26521 1 HDAC1 ATF1 TBL1XR1 ARNT FEZF1 CHAMP1 TCF12 GATA2 ELK1 ATF7 TEC TXK GC04M048219
GH04H048126 1.8 FANTOM5 Ensembl ENCODE dbSUPER 12.6 +139.2 139245 8 HDGF PKNOX1 FOXA2 ATF1 ARNT BRCA1 TCF12 GATA2 ZNF143 ATF7 TEC TXK RNU6-838P ENSG00000248254 CNGA1 ZAR1 ENSG00000283499
GH04H048267 1.3 ENCODE dbSUPER 17.3 +0.3 308 4 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF207 SP3 TEC SLAIN2 GC04M048219
GH04H048336 1.4 FANTOM5 ENCODE 14.1 -70.4 -70423 6 HDGF ARNT ARID4B SIN3A DMAP1 YY1 ZNF766 ZNF143 SP3 SP5 TEC ZAR1 TXK SLAIN2 SLC10A4 GC04M048291
GH04H048209 1.5 Ensembl ENCODE dbSUPER 12.1 +58.2 58237 3 HDGF PKNOX1 ATF1 ARNT YY1 TCF12 ZNF766 CBX5 GATA2 ELK1 SLAIN2 TEC NFXL1 PIR56443 GC04M048219
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TEC on UCSC Golden Path with GeneCards custom track

Promoters for TEC Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000168113 164 1801 HDGF ARID4B SIN3A DMAP1 ZNF2 YY1 ZNF143 ZNF207 SP3 SP5

Genomic Location for TEC Gene

Chromosome:
4
Start:
48,135,783 bp from pter
End:
48,269,864 bp from pter
Size:
134,082 bases
Orientation:
Minus strand

Genomic View for TEC Gene

Genes around TEC on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TEC Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TEC Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TEC Gene

Proteins for TEC Gene

  • Protein details for TEC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P42680-TEC_HUMAN
    Recommended name:
    Tyrosine-protein kinase Tec
    Protein Accession:
    P42680
    Secondary Accessions:
    • B7ZKZ6
    • Q3MIS5

    Protein attributes for TEC Gene

    Size:
    631 amino acids
    Molecular mass:
    73581 Da
    Cofactor:
    Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
    Quaternary structure:
    • Interacts with INPP5D/SHIP1 and INPPL1/SHIP2. Interacts with CD28, FASLG, FGF2, GRB10, LYN and KIT. Interacts with VAV1 and JAK2 (By similarity).

    Three dimensional structures from OCA and Proteopedia for TEC Gene

neXtProt entry for TEC Gene

Selected DME Specific Peptides for TEC Gene

P42680:
  • SSKSDVWSFGVLMWE
  • RDLAARN
  • SDVWSFGVLMWE
  • PIYIVTE
  • LVQLYGVC
  • KSDVWSFG
  • YYLAEKH

Post-translational modifications for TEC Gene

  • Following B-cell or T-cell receptors engagement, translocates to the plasma membrane where it gets phosphorylated at Tyr-519. Undergoes also tyrosine phosphorylation during platelet activation.
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TEC Gene

Domains & Families for TEC Gene

Gene Families for TEC Gene

Suggested Antigen Peptide Sequences for TEC Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P42680

UniProtKB/Swiss-Prot:

TEC_HUMAN :
  • The PH domain mediates the binding to inositol polyphosphate and phosphoinositides, leading to its targeting to the plasma membrane. It is extended in the BTK kinase family by a region designated the TH (Tec homology) domain, which consists of about 80 residues preceding the SH3 domain.
  • Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.
Domain:
  • The PH domain mediates the binding to inositol polyphosphate and phosphoinositides, leading to its targeting to the plasma membrane. It is extended in the BTK kinase family by a region designated the TH (Tec homology) domain, which consists of about 80 residues preceding the SH3 domain.
  • The SH3 domain is essential for its targeting to activated CD28 costimulatory molecule.
Family:
  • Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily.
genes like me logo Genes that share domains with TEC: view

Function for TEC Gene

Molecular function for TEC Gene

GENATLAS Biochemistry:
Tec non receptor protein tyrosine kinase,73.6kDa
UniProtKB/Swiss-Prot CatalyticActivity:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.
UniProtKB/Swiss-Prot EnzymeRegulation:
Activated by tyrosine phosphorylation by a wide range of cytokine stimulations. When T-cells or B-cells receptors are activated, a series of phosphorylation leads to the recruitment of TEC to the cell membrane, where it is phosphorylated at Tyr-519. Also activated in response to SCF. Integrin engagement induces tyrosine phosphorylation of TEC in platelets. STAP1 participates in a positive feedback loop by increasing the activity of TEC. SOCS1 is an inhibitor of TEC kinase activity.
UniProtKB/Swiss-Prot Function:
Non-receptor tyrosine kinase that contributes to signaling from many receptors and participates as a signal transducer in multiple downstream pathways, including regulation of the actin cytoskeleton. Plays a redundant role to ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. Required for TCR-dependent IL2 gene induction. Phosphorylates DOK1, one CD28-specific substrate, and contributes to CD28-signaling. Mediates signals that negatively regulate IL2RA expression induced by TCR cross-linking. Plays a redundant role to BTK in BCR-signaling for B-cell development and activation, especially by phosphorylating STAP1, a BCR-signaling protein. Required in mast cells for efficient cytokine production. Involved in both growth and differentiation mechanisms of myeloid cells through activation by the granulocyte colony-stimulating factor CSF3, a critical cytokine to promoting the growth, differentiation, and functional activation of myeloid cells. Participates in platelet signaling downstream of integrin activation. Cooperates with JAK2 through reciprocal phosphorylation to mediate cytokine-driven activation of FOS transcription. GRB10, a negative modifier of the FOS activation pathway, is another substrate of TEC. TEC is involved in G protein-coupled receptor- and integrin-mediated signalings in blood platelets. Plays a role in hepatocyte proliferation and liver regeneration and is involved in HGF-induced ERK signaling pathway. TEC regulates also FGF2 unconventional secretion (endoplasmic reticulum (ER)/Golgi-independent mechanism) under various physiological conditions through phosphorylation of FGF2 Tyr-215. May also be involved in the regulation of osteoclast differentiation.

Enzyme Numbers (IUBMB) for TEC Gene

Phenotypes From GWAS Catalog for TEC Gene

Gene Ontology (GO) - Molecular Function for TEC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004672 protein kinase activity IEA --
GO:0004713 protein tyrosine kinase activity IEA --
GO:0004715 non-membrane spanning protein tyrosine kinase activity IDA,TAS 10518561
GO:0005102 NOT receptor binding IBA --
GO:0005515 protein binding IPI 8892607
genes like me logo Genes that share ontologies with TEC: view
genes like me logo Genes that share phenotypes with TEC: view

Animal Models for TEC Gene

MGI Knock Outs for TEC:

Animal Model Products

CRISPR Products

miRNA for TEC Gene

miRTarBase miRNAs that target TEC

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for TEC
  • Applied Biological Materials Clones for TEC
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for TEC Gene

Localization for TEC Gene

Subcellular locations from UniProtKB/Swiss-Prot for TEC Gene

Cytoplasm. Cell membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Following B-cell or T-cell receptors activation by antigen, translocates to the plasma membrane through its PH domain. Thrombin and integrin engagement induces translocation of TEC to the cytoskeleton during platelet activation. In cardiac myocytes, assumes a diffuse intracellular localization under basal conditions but is recruited to striated structures upon various stimuli, including ATP (By similarity). {ECO:0000250}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TEC gene
Compartment Confidence
plasma membrane 5
cytoskeleton 5
cytosol 5
nucleus 2
peroxisome 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Plasma membrane (3)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for TEC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol TAS --
GO:0005856 cytoskeleton IDA,IEA 9299487
GO:0005886 plasma membrane IEA,IDA --
GO:0016020 membrane IEA --
genes like me logo Genes that share ontologies with TEC: view

Pathways & Interactions for TEC Gene

genes like me logo Genes that share pathways with TEC: view

SIGNOR curated interactions for TEC Gene

Activates:
Is activated by:

Gene Ontology (GO) - Biological Process for TEC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002250 adaptive immune response IEA --
GO:0002376 immune system process IEA --
GO:0006468 protein phosphorylation TAS,IEA 7934162
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA --
GO:0007229 integrin-mediated signaling pathway IDA 9652744
genes like me logo Genes that share ontologies with TEC: view

Drugs & Compounds for TEC Gene

(7) Drugs for TEC Gene - From: HMDB and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
ATP Nutra Agonist 0

(5) Additional Compounds for TEC Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
ADP
  • Adenosindiphosphorsaeure
  • Adenosine 5'-pyrophosphate
  • Adenosine diphosphate
  • Adenosine pyrophosphate
  • Adenosine-5'-diphosphate
Full agonist, Agonist 58-64-0
genes like me logo Genes that share compounds with TEC: view

Transcripts for TEC Gene

Unigene Clusters for TEC Gene

Tec protein tyrosine kinase:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Addgene plasmids for TEC
  • Applied Biological Materials Clones for TEC
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for TEC Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9 ^ 10 ^ 11a · 11b ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b
SP1: - -
SP2:
SP3: -
SP4:
SP5: -
SP6:

Relevant External Links for TEC Gene

GeneLoc Exon Structure for
TEC
ECgene alternative splicing isoforms for
TEC

Expression for TEC Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TEC Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for TEC Gene

This gene is overexpressed in Peripheral blood mononuclear cells (64.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TEC Gene



Protein tissue co-expression partners for TEC Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TEC Gene:

TEC

SOURCE GeneReport for Unigene cluster for TEC Gene:

Hs.479670

mRNA Expression by UniProt/SwissProt for TEC Gene:

P42680-TEC_HUMAN
Tissue specificity: Expressed in a wide range of cells, including hematopoietic cell lines like myeloid, B-, and T-cell lineages.

Evidence on tissue expression from TISSUES for TEC Gene

  • Blood(4.3)
  • Liver(4.1)
genes like me logo Genes that share expression patterns with TEC: view

Primer Products

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for TEC Gene

Orthologs for TEC Gene

This gene was present in the common ancestor of animals.

Orthologs for TEC Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TEC 34 33
  • 99.74 (n)
OneToOne
dog
(Canis familiaris)
Mammalia TEC 34 33
  • 92.02 (n)
OneToOne
cow
(Bos Taurus)
Mammalia TEC 34 33
  • 91.9 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Tec 33 16 34
  • 88.99 (n)
oppossum
(Monodelphis domestica)
Mammalia TEC 34
  • 88 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Tec 33
  • 87.76 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia TEC 34
  • 85 (a)
OneToOne
chicken
(Gallus gallus)
Aves TEC 34 33
  • 78.72 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TEC 34
  • 83 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia tec 33
  • 73.6 (n)
zebrafish
(Danio rerio)
Actinopterygii tec 34 33
  • 65.99 (n)
OneToOne
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.13650 33
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP008317 33
  • 55.74 (n)
fruit fly
(Drosophila melanogaster)
Insecta Btk29A 35 33 34
  • 52.72 (n)
worm
(Caenorhabditis elegans)
Secernentea spe-8 35
  • 32 (a)
F22B3.8 35
  • 28 (a)
kin-24 35
  • 25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.1818 34
  • 43 (a)
ManyToMany
-- 34
  • 34 (a)
ManyToMany
Species where no ortholog for TEC was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for TEC Gene

ENSEMBL:
Gene Tree for TEC (if available)
TreeFam:
Gene Tree for TEC (if available)

Paralogs for TEC Gene

Paralogs for TEC Gene

Pseudogenes.org Pseudogenes for TEC Gene

genes like me logo Genes that share paralogs with TEC: view

Variants for TEC Gene

Sequence variations from dbSNP and Humsavar for TEC Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
VAR_041851 A lung adenocarcinoma sample
rs1000047218 -- 48,248,700(+) ACTGT(A/G)AGATG intron-variant
rs1000050915 -- 48,148,519(+) AGAGA(G/T)TCAAG intron-variant
rs10000735 -- 48,186,953(+) gagaa(C/T)gggcc intron-variant
rs1000169638 -- 48,148,898(+) TAGCT(C/T)CCACT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TEC Gene

Variant ID Type Subtype PubMed ID
dgv5203n100 CNV loss 25217958
esv275189 CNV loss 21479260
esv2763359 CNV gain 21179565
nsv1006853 CNV gain 25217958
nsv1114520 CNV deletion 24896259
nsv4329 CNV deletion 18451855
nsv461357 CNV gain 19166990
nsv461358 CNV loss 19166990
nsv470032 CNV gain 18288195
nsv509003 CNV insertion 20534489
nsv594119 CNV gain 21841781
nsv594120 CNV loss 21841781
nsv819666 CNV loss 19587683
nsv819982 CNV loss 19587683
nsv820308 CNV loss 19587683

Variation tolerance for TEC Gene

Residual Variation Intolerance Score: 10.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.27; 25.43% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TEC Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TEC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TEC Gene

Disorders for TEC Gene

MalaCards: The human disease database

(1) MalaCards diseases for TEC Gene - From: OMIM

Disorder Aliases PubMed IDs
transient erythroblastopenia of childhood
  • erythroblastopenia, transient
- elite association - COSMIC cancer census association via MalaCards
Search TEC in MalaCards View complete list of genes associated with diseases

Relevant External Links for TEC

Genetic Association Database (GAD)
TEC
Human Genome Epidemiology (HuGE) Navigator
TEC
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TEC
genes like me logo Genes that share disorders with TEC: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TEC Gene

Publications for TEC Gene

  1. Molecular cloning and analysis of the human Tec protein-tyrosine kinase. (PMID: 7934162) Sato K … Hirai H (Leukemia 1994) 2 3 4 22 60
  2. Tec protein tyrosine kinase inhibits CD25 expression in human T-lymphocyte. (PMID: 19883687) Susaki K … Ishida T (Immunology letters 2010) 3 4 22 60
  3. SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase. (PMID: 15492005) Tomlinson MG … Weiss A (The Journal of biological chemistry 2004) 3 4 22 60
  4. Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases. (PMID: 12573241) Nore BF … Smith CI (Biochimica et biophysica acta 2003) 3 4 22 60
  5. Molecular cloning of a docking protein, BRDG1, that acts downstream of the Tec tyrosine kinase. (PMID: 10518561) Ohya K … Mano H (Proceedings of the National Academy of Sciences of the United States of America 1999) 3 4 22 60

Products for TEC Gene

  • Addgene plasmids for TEC

Sources for TEC Gene

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