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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TEAD3 Gene

protein-coding   GIFtS: 56
GCID: GC06M035441

TEA Domain Family Member 3


(Previous symbol: TEAD5)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
TEA Domain Family Member 31 2 3     TEF-52
TEAD51 2 3 5     TEA Domain Family Member 52
TEF52 3 5     Transcriptional Enhancer Factor 52
DTEF-12 3     Transcriptional Enhancer Factor TEF-52
TEAD-32 3     Transcriptional Enhancer Factor TEF-5 (DTEF-1)2
ETFR-12     

External Ids:    HGNC: 117161   Entrez Gene: 70052   Ensembl: ENSG000000078667   OMIM: 6031705   UniProtKB: Q995943   

Export aliases for TEAD3 gene to outside databases

Previous GC identifers: GC06M035443 GC06M035488 GC06M035549 GC06M035162


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TEAD3 Gene:
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which
contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and is involved in the
transactivation of the chorionic somatomammotropin-B gene enhancer. Translation of this protein is initiated at a
non-AUG (AUA) start codon. (provided by RefSeq, Jul 2008)

GeneCards Summary for TEAD3 Gene: 
TEAD3 (TEA domain family member 3) is a protein-coding gene. Diseases associated with TEAD3 include pharyngitis, and neuronitis, and among its related super-pathways are Gene Expression. GO annotations related to this gene include DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is TEAD1.

UniProtKB/Swiss-Prot: TEAD3_HUMAN, Q99594
Function: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ
size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway
is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates
and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates
YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell
proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional
elements of the human chorionic somatomammotropin-B gene enhancer

Gene Wiki entry for TEAD3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TEAD3 gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-1   E2F   E2F-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTEAD3 promoter sequence
   Search SABiosciences Chromatin IP Primers for TEAD3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEAD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.2   Ensembl cytogenetic band:  6p21.31   HGNC cytogenetic band: 6p21.2

TEAD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TEAD3 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M035441:  view genomic region     (about GC identifiers)

Start:
35,441,374 bp from pter      End:
35,464,861 bp from pter
Size:
23,488 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TEAD3_HUMAN, Q99594 (See protein sequence)
Recommended Name: Transcriptional enhancer factor TEF-5  
Size: 435 amino acids; 48676 Da
Subunit: Interacts with YAP1 and WWTR1/TAZ
Subcellular location: Nucleus
Sequence caution: Sequence=AAH27877.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator
methionine is coded by a non-canonical ATA isoleucine codon; Sequence=AAH91488.2; Type=Miscellaneous discrepancy;
Note=Unusual initiator. The initiator methionine is coded by a non-canonical ATA isoleucine codon;
Sequence=CAA64213.2; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by
a non-canonical ATA isoleucine codon;
Secondary accessions: O95910 Q5BJG7 Q8N6Y4

Explore the universe of human proteins at neXtProt for TEAD3: NX_Q99594

Explore proteomics data for TEAD3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q99594

  • TEAD3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TEAD3 Protein Expression
    REFSEQ proteins: NP_003205.2  
    ENSEMBL proteins: 
     ENSP00000384577   ENSP00000345772   ENSP00000416400  
    Reactome Protein details: Q99594
    Human Recombinant Protein Products for TEAD3: 
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    Novus Biologicals TEAD3 Proteins
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TEAD3 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005667transcription factor complex IEA--

    TEAD3 for ontologies           About GeneDecksing



    TEAD3 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    3 InterPro protein domains:
     IPR027253 TEF-5
     IPR000818 TEA/ATTS
     IPR016361 TEF

    Graphical View of Domain Structure for InterPro Entry Q99594

    ProtoNet protein and cluster: Q99594

    1 Blocks protein domain: IPB000818 TEA/ATTS family

    UniProtKB/Swiss-Prot: TEAD3_HUMAN, Q99594
    Similarity: Contains 1 TEA DNA-binding domain


    TEAD3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TEAD3_HUMAN, Q99594
    Function: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ
    size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway
    is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates
    and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates
    YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell
    proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional
    elements of the human chorionic somatomammotropin-B gene enhancer

         Genatlas biochemistry entry for TEAD3:
    SV40-transcriptional enhancer factor 3 (TEF5),expressed in syncytiotrophoblast,where it binds to CSH2 enhancer

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IDA18579750
    GO:0005515protein binding IPI18579750
         
    TEAD3 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TEAD3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TEAD3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TEAD3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TEAD3 

    miRNA
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    8/46 QIAGEN miScript miRNA Assays for microRNAs that regulate TEAD3 (see all 46):
    hsa-miR-323-3p hsa-miR-1321 hsa-let-7d hsa-miR-374a hsa-miR-3167 hsa-let-7g hsa-let-7a hsa-miR-518c
    SwitchGear 3'UTR luciferase reporter plasmidTEAD3 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEAD3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for TEAD3 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Generic Transcription Pathway
    Gene Expression0.47
    Generic Transcription Pathway0.47
    2Hippo signaling pathway
    Hippo signaling pathway
    3YAP1- and WWTR1 (TAZ)-stimulated gene expression
    YAP1- and WWTR1 (TAZ)-stimulated gene expression

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    3        Reactome Pathways for TEAD3
        Generic Transcription Pathway
    Gene Expression
    YAP1- and WWTR1 (TAZ)-stimulated gene expression


    1         Kegg Pathway  (Kegg details for TEAD3):
        Hippo signaling pathway


    TEAD3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEAD3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/30 Interacting proteins for TEAD3 (Q995943 ENSP000003457724) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    WWTR1Q9GZV53, ENSP000003538474I2D: score=5 STRING: ENSP00000353847
    CTBP2P565453, ENSP000003118254I2D: score=4 STRING: ENSP00000311825
    E2F1Q010943, ENSP000003455714I2D: score=1 STRING: ENSP00000345571
    MYH7P128833, ENSP000003475074I2D: score=1 STRING: ENSP00000347507
    TNIKQ9UKE53, ENSP000003995114I2D: score=1 STRING: ENSP00000399511
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS9148898
    GO:0006367transcription initiation from RNA polymerase II promoter TAS--
    GO:0007565female pregnancy TAS9148898
    GO:0010467gene expression TAS--

    TEAD3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TEAD3

    Search CenterWatch for drugs/clinical trials and news about TEAD3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TEAD3 gene: 
    NM_003214.3  

    Unigene Cluster for TEAD3:

    TEA domain family member 3
    Hs.485205  [show with all ESTs]
    Unigene Representative Sequence: AK226144
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000402886 ENST00000338863(uc003okt.3 uc003oku.4 uc010jvx.3)
    ENST00000433586
    miRNA
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    8/46 QIAGEN miScript miRNA Assays for microRNAs that regulate TEAD3 (see all 46):
    hsa-miR-323-3p hsa-miR-1321 hsa-let-7d hsa-miR-374a hsa-miR-3167 hsa-let-7g hsa-let-7a hsa-miR-518c
    SwitchGear 3'UTR luciferase reporter plasmidTEAD3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEAD3
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TEAD3 (NM_003214)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TEAD3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEAD3
    Sirion Biotech Customized lentivirus for stable overexpression of TEAD3 
                         Customized lentivirus expression plasmids for stable overexpression of TEAD3 
    Primer
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    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TEAD3
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEAD3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEAD3

    Additional mRNA sequence: 

    AK226144.1 BC010053.2 BC027877.1 BC091488.1 X94439.1 

    14 DOTS entries:

    DT.91725897  DT.445213  DT.100785354  DT.92007915  DT.100736862  DT.100785346  DT.121360533  DT.40234273 
    DT.75104023  DT.91728703  DT.91979498  DT.99947586  DT.100785348  DT.435102 

    24/186 AceView cDNA sequences (see all 186):

    BF435305 BC010053 CD516212 BE731877 BU944693 BM792363 AA852463 BC027877 
    BM910398 CA429546 BE732045 BX366766 AU131365 AI803742 X94439 AL047433 
    BX355885 BQ687363 AI571142 BM560903 AI219719 BQ719548 NM_003214 BU162821 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TEAD3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGAAGGGAG
    TEAD3 Expression
    About this image


    See TEAD3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TEAD3

    SOURCE GeneReport for Unigene cluster: Hs.485205

    UniProtKB/Swiss-Prot: TEAD3_HUMAN, Q99594
    Tissue specificity: Preferentially expressed in the placenta

        SABiosciences Custom PCR Arrays for TEAD3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEAD3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TEAD3 gene from 6/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tead31 , 5 TEA domain family member 31, 5 90.42(n)1
    97.7(a)1
      17 (14.66 cM)5
    216781  NM_001098226.31  NP_001091696.21 
     283316715 
    chicken
    (Gallus gallus)
    Aves TEAD31 TEA domain family member 3 82.76(n)
    90.53(a)
      395810  XM_003642731.1  XP_003642779.1 
    lizard
    (Anolis carolinensis)
    Reptilia TEAD36
    Uncharacterized protein
    84(a)
    1 ↔ 1
    4(124217125-124255451)
    zebrafish
    (Danio rerio)
    Actinopterygii tead3a1 TEA domain family member 3 a 75.74(n)
    82.5(a)
      386763  XM_003201166.1  XP_003201214.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta sd3 neurogenesis transcription factor 58(a)     --
    worm
    (Caenorhabditis elegans)
    Secernentea egl-443 Expression: hyp3, hyp4, hyp6, hyp7,
    intestine, pharyngeal muscle, head,
    ventral ganglia, retrovesicular
    ganglion, preanal ganglion, lumbar
    neurons, hypodermal, tail, tail
    neurons, intestinal, all stages less
    40(a)   II(5933501-5940191)   --


    ENSEMBL Gene Tree for TEAD3 (if available)
    TreeFam Gene Tree for TEAD3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TEAD3 gene
    TEAD12  TEAD42  TEAD22  
    3 SIMAP similar genes for TEAD3 using alignment to 4 protein entries:     TEAD3_HUMAN (see all proteins):
    TEAD4    TEAD1    TEAD2

    TEAD3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/538 SNPs in TEAD3 are shown (see all 538)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1841052931,2
    --35440910(+) GTGCCC/TGGCCG 1 -- ds50010--------
    rs569418391,2
    C,F--35440923(+) GAAAGT/GCTTGA 1 -- ds50012Minor allele frequency- G:0.17CSA WA 119
    rs1171551941,2
    C,F--35440929(+) CTTGAA/GCTATC 1 -- ds50011Minor allele frequency- G:0.05EA 120
    rs1168373581,2
    C,F--35441156(+) TGTGCG/AACCTT 1 -- ds50011Minor allele frequency- A:0.01WA 118
    rs119623351,2
    C,F,A,H--35441167(+) GAGCAA/CATCAC 1 -- ds500121Minor allele frequency- N:0.00EA NA NS WA CSA 1598
    rs1869652061,2
    --35441304(+) GGTGAC/TGACAC 1 -- ds50010--------
    rs2002765101,2
    C--35441405(+) ACTTTA/TATTTT 1 -- ut310--------
    rs1997823661,2
    C--35441428(-) CTGCTA/CAAAAA 1 -- ut310--------
    rs1931990441,2
    --35441607(+) AGCTCA/GGGCAG 1 -- ut310--------
    rs1849809921,2
    --35441636(+) AAGGGA/GCACAG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TEAD3 (35441374 - 35464861 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for TEAD3:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv528351CNV Loss19592680
    esv23268CNV Loss19812545
    nsv462909CNV Loss19166990
    nsv885799CNV Loss21882294
    nsv519370CNV Loss19592680
    dgv1940e1CNV Complex17122850

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 603170    OMIM disorders: --

    2 diseases for TEAD3:    About MalaCards
    pharyngitis    neuronitis


    TEAD3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TEAD3

    Export disorders for TEAD3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TEAD3 gene, integrated from 9 sources (see all 29):
    (articles sorted by number of sources associating them with TEAD3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human TEF-5 is preferentially expressed in placenta and binds to multiple functional elements of the human chorionic somatomammotropin- B gene enhancer. (PubMed id 9148898)1, 2, 3, 9 Jacquemin P.... Davidson I. (1997)
    2. Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis. (PubMed id 9889009)1, 3, 9 Jacquemin P....Davidson I. (1999)
    3. TEAD transcription factors mediate the function of TA Z in cell growth and epithelial-mesenchymal transition. (PubMed id 19324877)1, 2 Zhang H....Guan K.L. (2009)
    4. TEAD mediates YAP-dependent gene induction and growth control. (PubMed id 18579750)1, 2 Zhao B.... Guan K.L. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    7. Human placental TEF-5 transactivates the human chorionic somatomammotropin gene enhancer. (PubMed id 10379887)1, 9 Jiang S.W.... Eberhardt N.L. (1999)
    8. Transcription enhancer factor-5 and a GATA-like protein determine placental-specific expression of the Type I human 3beta-hydroxysteroid dehydrogenase gene, HSD3B1. (PubMed id 15131259)1, 9 Peng L....Payne A.H. (2004)
    9. YAP/TEAD-mediated transcription controls cellular sene scence. (PubMed id 23576552)1 Xie Q....Yuan Z. (2013)
    10. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7005 HGNC: 11716 AceView: TEAD3 Ensembl:ENSG00000007866 euGenes: HUgn7005
    ECgene: TEAD3 Kegg: 7005 H-InvDB: TEAD3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TEAD3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TEAD3 gene:
    Search GeneIP for patents involving TEAD3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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