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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TEAD3 Gene

protein-coding   GIFtS: 54
GCID: GC06M035441

TEA domain family member 3


(Previous symbol: TEAD5)
 Explore 3 diseases affiliated with
TEAD3 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TEAD3    

Aliases
for TEAD3 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
TEA Domain Family Member 31 2 3     TEAD-32 3
TEAD51 2 3 5     TEA Domain Family Member 52
TEF52 3 5     Transcriptional Enhancer Factor 52
ETFR-11 2     Transcriptional Enhancer Factor TEF-52
TEF-51 2     Transcriptional Enhancer Factor TEF-5 (DTEF-1)2
DTEF-12 3     

External Ids:    HGNC: 117161   Entrez Gene: 70052   Ensembl: ENSG000000078667   OMIM: 6031705   UniProtKB: Q995943   

Export aliases for TEAD3 gene to outside databases

Previous GC identifers: GC06M035443 GC06M035488 GC06M035549 GC06M035162


Summaries
for TEAD3 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TEAD3:
This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which
contain the TEA/ATTS DNA-binding domain. It is predominantly expressed in the placenta and is involved in the
transactivation of the chorionic somatomammotropin-B gene enhancer. Translation of this protein is initiated at a
non-AUG (AUA) start codon. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: TEAD3_HUMAN, Q99594
Function: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size
control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is
composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and
activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1
oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell
proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements
of the human chorionic somatomammotropin-B gene enhancer

Gene Wiki entry for TEAD3


Genomic Views
for TEAD3 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TEAD3 gene promoter:
         E2F-4   E2F-3a   E2F-5   E2F-1   E2F   E2F-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TEAD3 promoter sequence
   Search SABiosciences Chromatin IP Primers for TEAD3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEAD3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.2   Ensembl cytogenetic band:  6p21.31   HGNC cytogenetic band: 6p21.2

TEAD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TEAD3 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M035441:  view genomic region     (about GC identifiers)

Start:
 35,441,374 bp from pter      End:
 35,464,861 bp from pter
Size:
 23,488 bases      Orientation:
 minus strand

Proteins
for TEAD3 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TEAD3_HUMAN, Q99594 (See protein sequence)
Recommended Name: Transcriptional enhancer factor TEF-5  
Size: 435 amino acids; 48676 Da
Subunit: Interacts with YAP1 and WWTR1/TAZ
Subcellular location: Nucleus
Sequence caution: Sequence=AAH27877.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine
is coded by a non-canonical ATA isoleucine codon; Sequence=AAH91488.2; Type=Miscellaneous discrepancy; Note=Unusual
initiator. The initiator methionine is coded by a non-canonical ATA isoleucine codon; Sequence=CAA64213.2;
Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionine is coded by a non-canonical ATA
isoleucine codon;
Secondary accessions: O95910 Q5BJG7 Q8N6Y4

Explore the universe of human proteins at neXtProt for TEAD3: NX_Q99594

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q99594

    • TEAD3 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_003205.2  
    ENSEMBL proteins: 
     ENSP00000345772   ENSP00000384577   ENSP00000416400  
    Reactome Protein details: Q99594
    Human Recombinant Protein Products: 
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    Novus Biologicals TEAD3 Proteins
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TEAD3

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005654nucleoplasm TAS--
    GO:0005667transcription factor complex IEA--


    TEAD3 for ontologies           About GeneDecksing



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    Uscn Antibodies for TEAD3
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    Uscn ELISAs and CLIAs for TEAD3

    Protein Domains /
    Families
    for TEAD3 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TEAD3 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR027253 TEF-5
     IPR000818 TEA/ATTS
     IPR016361 TEF

    Graphical View of Domain Structure for InterPro Entry Q99594

    ProtoNet protein and cluster: Q99594

    1 Blocks protein family: IPB000818 TEA/ATTS family

    UniProtKB/Swiss-Prot: TEAD3_HUMAN, Q99594
    Similarity: Contains 1 TEA DNA-binding domain


    Function
    for TEAD3 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TEAD3_HUMAN, Q99594
    Function: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size
    control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is
    composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and
    activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1
    oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell
    proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to multiple functional elements
    of the human chorionic somatomammotropin-B gene enhancer

         Genatlas biochemistry entry for TEAD3:
    SV40-transcriptional enhancer factor 3 (TEF5),expressed in syncytiotrophoblast,where it binds to CSH2 enhancer

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TEAD3
    8/46 QIAGEN miScript miRNA Assays for microRNAs that regulate TEAD3 (see all 46):
    hsa-miR-323-3p hsa-miR-1321 hsa-let-7d hsa-miR-374a hsa-miR-3167 hsa-let-7g hsa-let-7a hsa-miR-518c
    SwitchGear 3'UTR luciferase reporter plasmid: TEAD3 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TEAD3 (see all 7)
    OriGene shRNA RFP: TEAD3
    OriGene siRNA: TEAD3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEAD3

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TEAD3

    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEAD3 (see all 4)
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEAD3 

    Cell Line
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    Search LifeMap BioReagents cell lines for TEAD3

    In Situ Assay
    Products:       
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    Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity IDA19324877
    GO:0005515protein binding IPI19324877


    TEAD3 for ontologies           About GeneDecksing



    Pathways & Interactions
    for TEAD3 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Generic Transcription Pathway
    		Generic Transcription Pathway1.00
    		Gene Expression0.46
    2YAP1- and WWTR1 (TAZ)-stimulated gene expression
    		YAP1- and WWTR1 (TAZ)-stimulated gene expression1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3        Reactome Pathways for TEAD3
        Generic Transcription Pathway
    Gene Expression
    YAP1- and WWTR1 (TAZ)-stimulated gene expression



    TEAD3 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TEAD3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/30 Interacting proteins for TEAD3 (Q995943 ENSP000003457724) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    WWTR1Q9GZV53, ENSP000003538474I2D: score=5 STRING: ENSP00000353847
    CTBP2P565453, ENSP000003118254I2D: score=4 STRING: ENSP00000311825
    E2F1Q010943, ENSP000003455714I2D: score=1 STRING: ENSP00000345571
    MYH7P128833, ENSP000003475074I2D: score=1 STRING: ENSP00000347507
    TNIKQ9UKE53, ENSP000003995114I2D: score=1 STRING: ENSP00000399511
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-dependent ----
    GO:0006357regulation of transcription from RNA polymerase II promoter TAS9148898
    GO:0006367transcription initiation from RNA polymerase II promoter TAS--
    GO:0007565female pregnancy TAS9148898
    GO:0010467gene expression TAS--


    TEAD3 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TEAD3 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TEAD3
    Search CenterWatch for drugs/clinical trials and news about TEAD3 

    Transcripts
    for TEAD3 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TEAD3 gene: 
    NM_003214.3  

    Unigene Cluster for TEAD3:

    TEA domain family member 3
    Hs.485205  [show with all ESTs]
    Unigene Representative Sequence: AK226144
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000338863(uc003okt.3 uc003oku.4 uc010jvx.3) ENST00000402886
    ENST00000433586

    miRNA
    Products:             		 OriGene 3'-UTR Clone: TEAD3
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TEAD3
    8/46 QIAGEN miScript miRNA Assays for microRNAs that regulate TEAD3 (see all 46):
    hsa-miR-323-3p hsa-miR-1321 hsa-let-7d hsa-miR-374a hsa-miR-3167 hsa-let-7g hsa-let-7a hsa-miR-518c
    SwitchGear 3'UTR luciferase reporter plasmid: TEAD3 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TEAD3 (see all 7)
    OriGene shRNA RFP: TEAD3
    OriGene siRNA: TEAD3
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEAD3
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEAD3
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    GenScript: all cDNA clones in your preferred vector: TEAD3 (NM_003214)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TEAD3
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEAD3 
    Primer
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    Browse OriGene validated miRNA SYBR primer pairs
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEAD3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEAD3

    Additional cDNA sequence: 

    AK226144.1 BC010053.2 BC027877.1 BC091488.1 X94439.1 

    14 DOTS entries:

    DT.91725897  DT.445213  DT.100785354  DT.92007915  DT.100736862  DT.100785346  DT.121360533  DT.40234273 
    DT.75104023  DT.91728703  DT.91979498  DT.99947586  DT.100785348  DT.435102 

    24/186 AceView cDNA sequences (see all 186):

    BE732045 AL047433 CA429546 X94439 BC010053 CD516212 AI571142 BX366766 
    BX355885 BM910398 BC027877 AU131365 NM_003214 BQ687363 BQ719548 BE731877 
    AI803742 BU162821 BF435305 AI219719 BM792363 AA852463 BM560903 BF083147 

    GeneLoc Exon Structure


    Expression
    for TEAD3 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TEAD3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAGAAGGGAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TEAD3 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    PureStem™ progenitor E69 (Embryonic Progenitor Cell)
    PureStem™ progenitor T36 (Embryonic Progenitor Cell)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See TEAD3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TEAD3

    SOURCE GeneReport for Unigene cluster: Hs.485205

    UniProtKB/Swiss-Prot: TEAD3_HUMAN, Q99594
    Tissue specificity: Preferentially expressed in the placenta

        SABiosciences Custom PCR Arrays for TEAD3
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEAD3

    Orthologs
    for TEAD3 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for TEAD3 gene from 5/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves TEAD31 TEA domain family member 3 82.76(n)
    90.53(a)    		   395810  XM_003642731.1  XP_003642779.1 
    lizard
    (Anolis carolinensis)    		 Reptilia TEAD36
    		 --
    		 83(a)
    		 1 ↔ 1
    		 4(124217145-124255451)
    zebrafish
    (Danio rerio)    		 Actinopterygii tead3a1 TEA domain family member 3 a 75.74(n)
    82.5(a)    		   386763  XM_003201166.1  XP_003201214.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta sd3 neurogenesis transcription factor 58(a)     --
    worm
    (Caenorhabditis elegans)    		 Secernentea egl-443 Expression: hyp3, hyp4, hyp6, hyp7,
    intestine, pharyngeal muscle, head, ventral
    ganglia, retrovesicular ganglion, preanal
    ganglion, lumbar neurons, hypodermal, tail,
    tail neurons, intestinal, all stages less    		 40(a)   II(5933501-5940191)   --


    ENSEMBL Gene Tree for TEAD3 (if available)
    TreeFam Gene Tree for TEAD3 (if available) 

    Paralogs
    for TEAD3 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TEAD3 gene
    TEAD12  TEAD42  TEAD22  
    3 SIMAP similar genes for TEAD3 using alignment to 4 protein entries:     TEAD3_HUMAN (see all proteins):
    TEAD4    TEAD1    TEAD2

    TEAD3 for paralogs           About GeneDecksing



    Genomic Variants
    for TEAD3 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/397 NCBI SNPs in TEAD3 are shown (see all 397)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1841052931,2
    		--35440910(+) GTGCCC/TGGCCG 1 -- ds50010--------
    rs569418391,2
    		--35440923(+) GAAAGT/GCTTGA 1 -- ds50012Minor allele frequency- G:0.17CSA WA 119
    rs1171551941,2
    		F,--35440929(+) CTTGAA/GCTATC 1 -- ds50011Minor allele frequency- G:0.05EA 120
    rs1168373581,2
    		--35441156(+) TGTGCG/AACCTT 1 -- ds50011Minor allele frequency- A:0.01WA 118
    rs119623351,2
    		C,F,A,H,--35441167(+) GAGCAA/CATCAC 1 -- ds500121Minor allele frequency- N:0.00EA NA NS WA CSA 1598
    rs1869652061,2
    		--35441304(+) GGTGAC/TGACAC 1 -- ds50010--------
    rs2002765101,2
    		C--35441405(+) ACTTTA/TATTTT 1 -- ut310--------
    rs1997823661,2
    		C--35441428(-) CTGCTA/CAAAAA 1 -- ut310--------
    rs1931990441,2
    		--35441607(+) AGCTCA/GGGCAG 1 -- ut310--------
    rs1849809921,2
    		--35441636(+) AAGGGA/GCACAG 1 -- ut310--------

    HapMap Linkage Disequilibrium report for TEAD3 (35441374 - 35464861 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 2 variations for TEAD3
         2 CNVs: 69486 3607

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    Disorders / Diseases
    for TEAD3 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TEAD3 for disorders           About GeneDecksing

    OMIM gene information: 603170    OMIM disorders: --

    3 diseases for TEAD3:    About MalaCards
    placental cancer    pharyngitis    neuronitis


    Export disorders for TEAD3 gene to outside databases

    Publications
    for TEAD3 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TEAD3 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with TEAD3)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Human TEF-5 is preferentially expressed in placenta and binds to multiple functional elements of the human chorionic somatomammotropin- B gene enhancer. (PubMed id 9148898)1, 2, 3, 9 Jacquemin P.... Davidson I. (1997)
    2. Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis. (PubMed id 9889009)1, 3, 9 Jacquemin P....Davidson I. (1999)
    3. TEAD transcription factors mediate the function of TA Z in cell growth and epithelial-mesenchymal transition. (PubMed id 19324877)1, 2 Zhang H....Guan K.L. (2009)
    4. TEAD mediates YAP-dependent gene induction and growth control. (PubMed id 18579750)1, 2 Zhao B.... Guan K.L. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    7. Human placental TEF-5 transactivates the human chorionic somatomammotropin gene enhancer. (PubMed id 10379887)1, 9 Jiang S.W.... Eberhardt N.L. (1999)
    8. Transcription enhancer factor-5 and a GATA-like protein determine placental-specific expression of the Type I human 3beta-hydroxysteroid dehydrogenase gene, HSD3B1. (PubMed id 15131259)1, 9 Peng L....Payne A.H. (2004)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)

    External Searches for TEAD3 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Genome Databases showing TEAD3 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 7005 HGNC: 11716 AceView: TEAD3 Ensembl:ENSG00000007866 euGenes: HUgn7005
    ECgene: TEAD3 H-InvDB: TEAD3

    Other Databases showing TEAD3 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TEAD3 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TEAD3 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TEAD3 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TEAD3 gene:
    Search GeneIP for patents involving TEAD3

    GeneCards and IP:
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