TEAD1 Gene
protein-coding GIFtS: 60
GCID: GC11P012652
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|
TEA domain family member 1 (SV40 transcriptional enhancer...(Previous names: atrophia areata, peripapillary chorioretinal degeneration...)
(Previous symbols: TCF13, AA)
| |
Aliases
for TEAD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| TEA Domain Family Member 1 (SV40 Transcriptional Enhancer Factor)1 2 | | TEAD-12 3 | | TCF131 2 3 5 | | REF12 5 | | AA1 2 | | Atrophia Areata, Peripapillary Chorioretinal Degeneration1 | | TEF-11 2 | | Transcriptional Enhancer Factor 12 | | Protein GT-IIC2 3 | | Transcriptional Enhancer Factor TEF-12 | | Transcription Factor 132 3 | | TEF13 | | NTEF-12 3 | | TEA Domain Family Member 13 | | TCF-132 3 | | |
Export aliases for TEAD1 gene to outside databasesPrevious GC identifers: GC11P014056 GC11P013515 GC11P012737 GC11P012730 GC11P012660 GC11P012376 |
Summaries
for TEAD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for TEAD1:
This gene encodes a ubiquitous transcriptional enhancer factor that is a member of the TEA/ATTS domain family. Thisprotein directs the transactivation of a wide variety of genes and, in placental cells, also acts as a transcriptionalrepressor. Mutations in this gene cause Sveinsson's chorioretinal atrophy. Additional transcript variants have beendescribed but their full-length natures have not been experimentally verified. (provided by RefSeq, May 2010)
UniProtKB/Swiss-Prot: TEAD1_HUMAN, P28347Function: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ sizecontrol and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway iscomposed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates andactivates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cellproliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperativelyto the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. Theactivation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF).Involved in cardiac development. Binds to the M-CAT motif
Gene Wiki entry for TEAD1
|
Genomic Views
for TEAD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TEAD1 gene promoter:
Sp1 CUTL1 AP-2gamma SREBP-1a GATA-6 FOXO4 AP-2beta AP-2alpha AP-2alphaA Ik-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for TEAD1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEAD1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p15.2 Ensembl cytogenetic band: 11p15.3 HGNC cytogenetic band: 11p15.4TEAD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11P012652: view genomic region
(about GC identifiers)
Start:
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12,695,969 bp from pter |
End:
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12,966,298 bp from pter |
Size:
|
270,330 bases |
Orientation:
|
plus strand |
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Proteins
for TEAD1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TEAD1_HUMAN, P28347 (See
protein sequence)Recommended Name: Transcriptional enhancer factor TEF-1 Size: 426 amino acids; 47946 Da
Subunit: Interacts with YAP1 and WWTR1/TAZ
Subcellular location: Nucleus
Caution: It is uncertain whether Met-1 or Met-16 is the initiator
Sequence caution: Sequence=AAB00791.1; Type=Miscellaneous discrepancy; Note=Unusual initiator. The initiator methionineis coded by a non-canonical ATT isoleucine codon;
2 PDB 3D structures from  and Proteopedia  for TEAD1:2HZD (3D)
3KYS (3D)
Explore the universe of human proteins at neXtProt for TEAD1: NX_P28347
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P28347
TEAD1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_068780.2
ENSEMBL proteins: ENSP00000435233 ENSP00000432587 ENSP00000435977 ENSP00000435393 ENSP00000354588 ENSP00000355332 ENSP00000334754 Reactome Protein details: P28347
Human Recombinant Protein Products for TEAD1:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
TEAD1 for ontologies About GeneDecksing
TEAD1 Antibody Products:
Assay Products for TEAD1: |
Protein
Domains /
Families
for TEAD1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TEAD1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P28347ProtoNet protein and cluster: P28347 1 Blocks protein family: IPB000818 TEA/ATTS family
UniProtKB/Swiss-Prot: TEAD1_HUMAN, P28347Similarity: Contains 1 TEA DNA-binding domain |
Function
for TEAD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: TEAD1_HUMAN, P28347Function: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ sizecontrol and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway iscomposed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates andactivates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cellproliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperativelyto the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. Theactivation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF).Involved in cardiac development. Binds to the M-CAT motif Genatlas biochemistry entry for TEAD1:SV40-transcriptional enhancer factor 1,required for cardiac muscle specific genes expression
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
TEAD1 for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for TEAD1:
7 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Tead1):
TEAD1 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Tead1tm1Hssk for TEAD1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEAD1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEAD1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: TEAD1 (NM_021961) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEAD1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEAD1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEAD1 |
|
Pathways & Interactions
for TEAD1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways - 5/8 super-pathways (see all 8) About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Generic Transcription Pathway | | | 2 | Human Embryonic Stem Cell Pluripotency | | | 3 | Rho Family GTPases | | | 4 | Wnt / Hedgehog / Notch | | | 5 | YAP1- and WWTR1 (TAZ)-stimulated gene expression | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/7 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for TEAD1 (see all 7)
1 
Cell Signaling Technology (CST) Pathway for TEAD1
3 
Reactome Pathways for TEAD1
TEAD1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for TEAD1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/36 Interacting proteins for TEAD1 (P283471, 2, 3 ENSP000003545884) via UniProtKB, MINT, STRING, and/or I2D (see all 36)About this table
Gene Ontology (GO): 5/11 biological process terms (GO ID links to tree view) (see all 11): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003143 | embryonic heart tube morphogenesis |
-- | -- | | GO:0006355 | regulation of transcription, DNA-dependent |
-- | -- | | GO:0006367 | transcription initiation from RNA polymerase II promoter |
TAS | -- | | GO:0007507 | heart development |
-- | -- | | GO:0010467 | gene expression |
TAS | -- |
TEAD1 for ontologies About GeneDecksing
|
Drugs & Compounds
for TEAD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
TEAD1 for compounds About GeneDecksing
 Browse Tocris compounds for TEAD1
4 Novoseek chemical compound relationships for TEAD1 gene About this table
Search CenterWatch for drugs/clinical trials and news about TEAD1
|
Transcripts
for TEAD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for TEAD1 gene: NM_021961.5 Unigene Cluster for TEAD1: TEA domain family member 1 (SV40 transcriptional enhancer factor) Hs.655331 [show with all ESTs]Unigene Representative Sequence: NM_0219618 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000527636 ENST00000527376 ENST00000527575 ENST00000525312(uc009ygk.3)
ENST00000526600(uc001mkk.4) ENST00000361985 ENST00000361905(uc021qdx.1 uc009ygl.3)
ENST00000334310
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEAD1 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEAD1 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: TEAD1 (NM_021961) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TEAD1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEAD1 |
Additional cDNA sequence: AB209858.1 AK027342.1 AK075070.1 AK075176.1 AK075236.1 AK310928.1 AL117450.1 AL133574.1 AL833289.1 BC026959.1 BC115398.1 8 DOTS entries: DT.95165276 DT.211047 DT.91754982 DT.95149550 DT.95094369 DT.120680290 DT.40131519 DT.95210648 24/279 AceView cDNA sequences (see all 279): AA040787 AA311260 AA767678 BM314308 N99407 AW188012 CR617889 BM799501 BM314618 N73785 BQ716476 NM_021961 AW473734 BG656258 AI597851 AA151355 AI702532 AW304047 AI698059 BF447913 BF942458 AA041222 AI754735 AW070709
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for TEAD1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | - | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for TEAD1
|
Expression
for TEAD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TEAD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TCTTTGCAAA
About this image
See TEAD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TEAD1
SOURCE GeneReport for Unigene cluster: Hs.655331
UniProtKB/Swiss-Prot: TEAD1_HUMAN, P28347Tissue specificity: Preferentially expressed in skeletal muscle. Lower levels in pancreas, placenta, and heart
SABiosciences Custom PCR Arrays for TEAD1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEAD1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TEAD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEAD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEAD1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEAD1 |
Orthologs
for TEAD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TEAD1 gene from 6/23 species (see all 23) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
TEAD11 |
TEA domain family member 1 (SV40 transcriptional enhancer more |
87.66(n)
98.53(a) |
|
403089 NM_001199405.1 NP_001186334.1 |
lizard
(Anolis carolinensis) |
Reptilia |
TEAD16 |
-- |
91(a) |
1 ↔ 1 |
GL343237.1(1132976-1199621) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.290882 |
Xenopus laevis transcribed sequence with moderate similarity more |
75.66(n) |
|
BQ728229.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
LOC1005374671 |
transcriptional enhancer factor TEF-1-like |
80.52(n)
91.08(a) |
|
100537467 XM_003199012.1 XP_003199060.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
sd1 , 3 |
neurogenesis transcription factor3
scalloped1 |
60(a)3
63.32(n)1
69.29(a)1 |
|
325361 NM_001103520.21 NP_001096990.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
egl-446 |
Transcription enhancer factor-like protein egl-44 |
34(a) |
1 → many |
II(5933469-5940777) |
ENSEMBL Gene Tree for TEAD1 (if available)
TreeFam Gene Tree for TEAD1 (if available) |
Paralogs
for TEAD1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for TEAD1 gene
- TEAD42 TEAD22 TEAD32
3 SIMAP similar genes for TEAD1 using alignment to 6 protein entries: TEAD1_HUMAN (see all proteins):TEAD4 TEAD3 TEAD2
TEAD1 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for TEAD1
PGOHUM00000242532
|
Genomic Variants
for TEAD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TEAD1 (12695969 - 12945969 bp, first 250kb of TEAD1)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 5 variations for TEAD1
5 Indels: 61103 39806 11539 101141 44830
Human Gene Mutation Database (HGMD): TEAD1
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEAD1 |
|
Disorders
/ Diseases
for TEAD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TEAD1 for disorders About GeneDecksing
OMIM gene information: 189967
OMIM disorders: 108985
UniProtKB/Swiss-Prot: TEAD1_HUMAN, P28347
Defects in TEAD1 are the cause of Sveinsson chorioretinal atrophy (SCRA) [MIM:108985]; also known as atrophiaareata (AA) or helicoidal peripapillary chorioretinal degeneration (HPCD). SCRA is characterized by symmetricallesions radiating from the optic disk involving the retina and the choroid
14  diseases for TEAD1: About MalaCardschorioretinitis atrophia areata chorioretinal atrophy sveinsson choreoretinal atrophy
spontaneous abortion choriocarcinoma cervicitis cervical carcinoma
cervical cancer choroiditis prostate cancer prostatitis
carcinoma hepatitis
1 Novoseek disease relationship for TEAD1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| choriocarcinoma |
59 |
4 |
7775450 (1), 8621623 (1), 9259314 (1) |
Human Genome Epidemiology (HuGE) Navigator: TEAD1 (1 document)
Export disorders for TEAD1 gene to outside databases
|
Publications
for TEAD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TEAD1 gene, integrated from 9 sources (see all 113):
(articles sorted by number of sources associating them with TEAD1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1. (PubMed id 1851669)1, 2, 3, 9 Xiao J.H.... Chambon P. (1991)
- A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration). (PubMed id 15016762)1, 2, 3, 9 Fossdal R....Stefansson K. (2004)
- TEAD transcription factors mediate the function of TA Z in cell growth and epithelial-mesenchymal transition. (PubMed id 19324877)1, 2 Zhang H....Guan K.L. (2009)
- TEAD mediates YAP-dependent gene induction and growth control. (PubMed id 18579750)1, 2 Zhao B.... Guan K.L. (2008)
- Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis. (PubMed id 9889009)1, 3 Jacquemin P....Davidson I. (1999)
- Physical interaction between the MADS box of serum response factor and the TEA/ATTS DNA-binding domain of transcription enhancer factor-1. (PubMed id 11136726)1, 9 Gupta M....Gupta M.P. (2001)
- Transcriptional enhancer factor-1 in cardiac myocytes interacts with an alpha 1-adrenergic- and beta-protein kinase C-inducible element in the rat beta-myosin heavy chain promoter. (PubMed id 8253797)1, 9 Kariya K....Simpson P.C. (1993)
- Cloning of human RTEF-1, a transcriptional enhancer factor-1-related gene preferentially expressed in skeletal muscle: evidence for an ancient multigene family. (PubMed id 8921372)1, 9 Stewart A.F.R.... Adra C.N. (1996)
- Transcriptional enhancer factor 1 (TEF-1/TEAD1) mediates activation of IFITM3 gene by BRGl. (PubMed id 18177740)1, 9 Cuddapah S....Zhao K. (2008)
- Mammalian vestigial-like 2, a cofactor of TEF-1 and MEF2 transcription factors that promotes skeletal muscle differentiation. (PubMed id 12376544)1, 9 Maeda T.... Stewart A.F. (2002)
|
External Searches for TEAD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TEAD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TEAD1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TEAD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for TEAD1 | Pharmacogenomics, SNPs, Pathways |
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About This Section
| Patent Information for TEAD1 gene:
Search GeneIP for patents involving TEAD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for TEAD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
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| | |  | OriGene Antibodies for TEAD1 | | OriGene shRNA RFP for TEAD1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TEAD1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TEAD1 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for TEAD1 | | OriGene 3'-UTR Clone for TEAD1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TEAD1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TEAD1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for TEAD1 | | OriGene Custom Protein Services for TEAD1 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TEAD1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TEAD1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TEAD1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TEAD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TEAD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TEAD1 |
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| | Antibodies & Assays for TEAD1 |
| | | | Search Tocris compounds for TEAD1 |
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 | | | TEAD1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TEAD1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for TEAD1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TEAD1 |
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