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Aliases for TDRP Gene

Aliases for TDRP Gene

  • Testis Development Related Protein 2 3
  • C8orf42 3 4
  • Chromosome 8 Open Reading Frame 42 2
  • Testis Development-Related Protein 3
  • Protein INM01 4
  • Inm01 3
  • TDRP1 3
  • TDRP2 3

External Ids for TDRP Gene

Previous HGNC Symbols for TDRP Gene

  • C8orf42

Previous GeneCards Identifiers for TDRP Gene

  • GC08M000440
  • GC08M000443

Summaries for TDRP Gene

GeneCards Summary for TDRP Gene

TDRP (Testis Development Related Protein) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TDRP Gene

Genomics for TDRP Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TDRP Gene

456,462 bp from pter
545,781 bp from pter
89,320 bases
Minus strand

Genomic View for TDRP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TDRP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TDRP Gene

No data available for Regulatory Elements for TDRP Gene

Proteins for TDRP Gene

  • Protein details for TDRP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Testis development-related protein
    Protein Accession:
    Secondary Accessions:
    • B6VF03
    • B9EG53

    Protein attributes for TDRP Gene

    185 amino acids
    Molecular mass:
    20403 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TDRP Gene


neXtProt entry for TDRP Gene

Proteomics data for TDRP Gene at MOPED

Post-translational modifications for TDRP Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TDRP Gene

No data available for DME Specific Peptides for TDRP Gene

Domains for TDRP Gene

Protein Domains for TDRP Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TDRP: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TDRP Gene

Function for TDRP Gene

Gene Ontology (GO) - Molecular Function for TDRP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with TDRP: view

Animal Model Products

miRNA for TDRP Gene

miRTarBase miRNAs that target TDRP

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TDRP Gene

Localization for TDRP Gene

Subcellular locations from UniProtKB/Swiss-Prot for TDRP Gene

Nucleus. Cytoplasm.

Gene Ontology (GO) - Cellular Components for TDRP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IDA 20170638
GO:0005737 cytoplasm IDA 20170638
genes like me logo Genes that share ontologies with TDRP: view

No data available for Subcellular locations from COMPARTMENTS for TDRP Gene

Pathways for TDRP Gene

SuperPathways for TDRP Gene

No Data Available

Interacting Proteins for TDRP Gene

Gene Ontology (GO) - Biological Process for TDRP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007283 spermatogenesis IDA 20170638
genes like me logo Genes that share ontologies with TDRP: view

No data available for Pathways by source for TDRP Gene

Transcripts for TDRP Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TDRP

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TDRP Gene

No ASD Table

Relevant External Links for TDRP Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TDRP Gene

mRNA expression in normal human tissues for TDRP Gene

Protein differential expression in normal tissues for TDRP Gene

This gene is overexpressed in Peripheral blood mononuclear cells (29.7), Platelet (21.4), and Placenta (11.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TDRP Gene

mRNA Expression by UniProt/SwissProt for TDRP Gene

Tissue specificity: Expressed in spermatogenic cells, especially in spermatocytes (at protein level).
genes like me logo Genes that share expressions with TDRP: view

Expression partners for TDRP Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for TDRP Gene

Orthologs for TDRP Gene

This gene was present in the common ancestor of chordates.

Orthologs for TDRP Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia C1H8orf42 35
  • 82.43 (n)
  • 78.26 (a)
  • 69 (a)
(Canis familiaris)
Mammalia C25H8orf42 35
  • 84.68 (n)
  • 82.16 (a)
  • 76 (a)
(Mus musculus)
Mammalia Tdrp 35
  • 78.45 (n)
  • 76.8 (a)
2610019F03Rik 16
Tdrp 36
  • 70 (a)
(Pan troglodytes)
Mammalia C8H8orf42 35
  • 99.46 (n)
  • 99.46 (a)
  • 98 (a)
(Rattus norvegicus)
Mammalia Tdrp 35
  • 77.9 (n)
  • 74.59 (a)
(Monodelphis domestica)
Mammalia TDRP 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia TDRP 36
  • 54 (a)
(Gallus gallus)
Aves C8ORF42 35
  • 72.41 (n)
  • 71.03 (a)
  • 54 (a)
(Anolis carolinensis)
Reptilia TDRP 36
  • 50 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia Str.15789 35
tdrp 35
  • 64.68 (n)
  • 57.84 (a)
African clawed frog
(Xenopus laevis)
Amphibia Xl.2936 35
Species with no ortholog for TDRP:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TDRP Gene

Gene Tree for TDRP (if available)
Gene Tree for TDRP (if available)

Paralogs for TDRP Gene

No data available for Paralogs for TDRP Gene

Variants for TDRP Gene

Polymorphic Variants from UniProtKB/Swiss-Prot for TDRP Gene

The poly-Ala region seems to be polymorphic and the number of Ala varies between 4 and 6

Sequence variations from dbSNP and Humsavar for TDRP Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type MAF
rs1760 -- 492,079(+) TGAAA(A/G)TCATT intron-variant, utr-variant-3-prime
rs2241 -- 505,383(+) AAAGG(A/G)TAAAT intron-variant
rs2242 -- 505,360(+) ACAGG(G/T)GTGGG intron-variant
rs7864 -- 477,913(+) CAACC(C/T)GATTT intron-variant
rs12209 -- 491,041(-) TTATG(C/G)AAAAA utr-variant-3-prime, intron-variant

Relevant External Links for TDRP Gene

HapMap Linkage Disequilibrium report

No data available for Structural Variations from Database of Genomic Variants (DGV) for TDRP Gene

Disorders for TDRP Gene

No disorders were found for TDRP Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TDRP Gene

Publications for TDRP Gene

  1. Molecular cloning of a novel nuclear factor, TDRP1, in spermatogenic cells of testis and its relationship with spermatogenesis. (PMID: 20170638) Wang X. … Hu R. (Biochem. Biophys. Res. Commun. 2010) 2 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3
  3. Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels. (PMID: 21646302) Bielinski S.J. … Chute C.G. (Mayo Clin. Proc. 2011) 3
  4. Association study of newly identified age-related macular degeneration susceptible loci SOD2, MBP, and C8orf42 in Han Chinese population. (PMID: 24667176) Kan M. … Liu Y. (Diagn Pathol 2014) 3
  5. Gene expression profiling in human insulinoma tissue: genes involved in the insulin secretion pathway and cloning of novel full-length cDNAs. (PMID: 15163304) Wang X.-C. … Hu R.-M. (Endocr. Relat. Cancer 2004) 4

Products for TDRP Gene

Sources for TDRP Gene

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