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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TDRKH Gene

protein-coding GIFtS: 51
GCID: GC01M151745

tudor and KH domain containing

(Previous name: tudor and KH domain containing )

Explore 9 diseases affiliated with
TDRKH via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Tudor And KH Domain Containing¹ ²		Tudor And KH Domain Containing Protein²
TDRD2¹ ² ³		Tudor And KH Domain-Containing Protein²
Tudor Domain-Containing Protein 2² ³		Tudor Domain Containing 2²
Putative RNA Binding Protein²

External Ids:	HGNC: 11713¹	Entrez Gene: 11022²	Ensembl: ENSG00000182134⁷	OMIM: 609501⁵	UniProtKB: Q9Y2W6³

Export aliases for TDRKH gene to outside databases

Previous GC identifers: GC01M149584 GC01M147526 GC01M148517 GC01M148960 GC01M148557 GC01M150010 GC01M123120

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Gene Wiki entry for TDRKH

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TDRKH gene promoter:
Elk-1 AP-1 p53 AP-4 AREB6 c-Rel HOXA5 Pax-4a NF-Y CBF(2)
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TDRKH promoter sequence

Search SABiosciences Chromatin IP Primers for TDRKH

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TDRKH

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21 Ensembl cytogenetic band: 1q21.3 HGNC cytogenetic band: 1q21

TDRKH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TDRKH gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M151745: view genomic region (about GC identifiers)

Start:	151,742,583 bp from pter	End:	151,763,892 bp from pter
Size:	21,310 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TDRKH_HUMAN, Q9Y2W6 (See protein sequence)

Recommended Name: Tudor and KH domain-containing protein

Size: 561 amino acids; 62046 Da

Subunit: Interacts with PIWIL1 and PIWIL4 (By similarity)

Sequence caution: Sequence=AAD30971.1; Type=Erroneous termination; Positions=562; Note=Translated as stop;

Sequence=BC022467; Type=Erroneous termination; Positions=175; Note=Translated as Lys;

2 PDB 3D structures from and Proteopedia for TDRKH:

2DIQ (3D)

3FDR (3D)

Secondary accessions: D3DV24 Q5SZR3 Q5SZR5 Q8N582 Q9NYV5

Alternative splicing: 2 isoforms: Q9Y2W6-2 Q9Y2W6-3

Explore the universe of human proteins at neXtProt for TDRKH: NX_Q9Y2W6

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9Y2W6

TDRKH Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (4 alternative transcripts):

NP_001077432.1 NP_001077433.1 NP_001077434.1 NP_006853.2

ENSEMBL proteins:

ENSP00000437147 ENSP00000357819 ENSP00000357817 ENSP00000357815 ENSP00000357813

ENSP00000357812 ENSP00000395718 ENSP00000433678 ENSP00000431557 ENSP00000432452

ENSP00000416645

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	Uscn Proteins for TDRKH

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	--	--
GO:0005739	mitochondrion	IEA	--

TDRKH for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for TDRKH

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TDRKH for domains About GeneDecksing

3 InterPro domains/families:

IPR004087 KH_dom

IPR004088 KH_dom_type_1

IPR002999 Tudor

Graphical View of Domain Structure for InterPro Entry Q9Y2W6

ProtoNet protein and cluster: Q9Y2W6

4 Blocks protein families:

IPB002999 Tudor domain

IPB004087 KH domain

IPB004088 KH

IPB008191 Maternal tudor protein

UniProtKB/Swiss-Prot: TDRKH_HUMAN, Q9Y2W6

Similarity: Contains 2 KH domains

Similarity: Contains 1 Tudor domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003723	RNA binding	IEA	--
GO:0005515	protein binding	--	--

TDRKH for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TDRKH

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		hsa-miR-485-5p hsa-miR-146a hsa-miR-548v hsa-miR-1205 hsa-miR-1184 hsa-miR-3622b-3p hsa-miR-205* hsa-miR-330-3p

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TDRKH

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TDRKH

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for TDRKH (Q9Y2W6³ ENSP00000357812⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PIWIL1	Q96J94³, ENSP00000245255⁴	I2D: score=1 STRING: ENSP00000245255
--	ENSP00000406965⁴	STRING: ENSP00000406965

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TDRKH
Search CenterWatch for drugs/clinical trials and news about TDRKH

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TDRKH gene (4 alternative transcripts):

NM_001083963.1 NM_001083964.1 NM_001083965.1 NM_006862.3

Unigene Cluster for TDRKH:

Tudor and KH domain containing

Hs.144439 [show with all ESTs]

Unigene Representative Sequence: AK225160

15 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000525790(uc001eyy.2) ENST00000368827(uc009wnb.1) ENST00000368825

ENST00000368824(uc001ezb.4 uc001ezc.4 uc001eza.4 uc001ezd.4 uc010pdn.1)

ENST00000368823 ENST00000368822 ENST00000458431 ENST00000526413 ENST00000484421

ENST00000486986 ENST00000526378 ENST00000494725 ENST00000530202 ENST00000463553

ENST00000440583

miRNA Products:		OriGene 3'-UTR Clone (see all 4): TDRKH Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TDRKH
		8/21 QIAGEN miScript miRNA Assays for microRNAs that regulate TDRKH (see all 21):
		hsa-miR-485-5p hsa-miR-146a hsa-miR-548v hsa-miR-1205 hsa-miR-1184 hsa-miR-3622b-3p hsa-miR-205* hsa-miR-330-3p

		SwitchGear 3'UTR luciferase reporter plasmid: TDRKH 3' UTR sequence

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Additional cDNA sequence:

AF119121.2 AF227192.1 AK056402.1 AK225160.1 AK226092.1 AK295948.1 AK303063.1 AK316279.1

BC022467.1 BC032690.1

11 DOTS entries:

DT.309114 DT.100780973 DT.40129661 DT.102842755 DT.95167247 DT.452303 DT.121399300 DT.121399340

DT.422794 DT.91704117 DT.95237379

24/97 AceView cDNA sequences (see all 97):

CA416063 BQ613819 BE890740 AF119121 AA883334 BU542162 AI621078 BI914192

CF141109 CR601319 AL598977 BI554111 CB164159 AI561125 BQ434621 BQ024437

BQ185258 AI381919 NM_006862 CB122701 AI923858 AW296176 AI632917 AA360929

GeneLoc Exon Structure

5/10 Alternative Splicing Database (ASD) splice patterns (SP) for TDRKH (see all 10) About this scheme

ExUns:	1a	·	1b	·	1c	·	1d	·	1e	·	1f	^	2	^	3a	·	3b	^	4	^	5a	·	5b	·	5c	·	5d	·	5e	^	6a	·	6b	·	6c	^	7a	·	7b	^	8	^	9	^	10	^	11	^	12a	·	12b	^
SP1:													-		-														-
SP2:													-		-														-
SP3:											-		-		-						-								-
SP4:											-		-		-														-
SP5:													-		-										-		-		-

ExUns:	13	^	14	^	15a	·	15b	·	15c	^	16
SP1:					-		-		-
SP2:
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for TDRKH

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TDRKH expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CTCGTTAAGA

About this image

TDRKH expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Primordial germ cell-like cells (Reconstitution of mo...)

Epiblast-like cells (Reconstitution of mo...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TDRKH Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TDRKH

SOURCE GeneReport for Unigene cluster: Hs.144439

SABiosciences Custom PCR Arrays for TDRKH

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for TDRKH gene from 6/19 species (see all 19) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Tdrkh^{1 , 5}	tudor and KH domain containing protein^{1, 5}	89.96(n)¹ 91.76(a)¹		3 (40.62 cM)⁵ 72634¹ NM_028307.1¹ NP_082583.1¹ 94413318⁵
chicken (Gallus gallus)	Aves	TDRKH¹	tudor and KH domain containing	61.11(n) 59.74(a)		425667 XM_423400.3 XP_423400.3
lizard (Anolis carolinensis)	Reptilia	TDRKH⁶	--	58(a)	1 ↔ 1	AAWZ02036993(2827-19564)
African clawed frog (Xenopus laevis)	Amphibia	48048892²	--	74.26(n)		48048892
zebrafish (Danio rerio)	Actinopterygii	zgc:113056¹	zgc:113056	52.64(n) 45.17(a)		541541 NM_001014355.1 NP_001014377.1
fruit fly (Drosophila melanogaster)	Insecta	CG7082¹	CG7082	44.91(n) 34.73(a)		33401 NM_134813.2 NP_608657.1

ENSEMBL Gene Tree for TDRKH (if available)
TreeFam Gene Tree for TDRKH (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TDRKH gene

TDRD7² TDRD5²

1 SIMAP similar gene for TDRKH using alignment to 6 protein entries: TDRKH_HUMAN (see all proteins):

NOVA1

TDRKH for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs75093131^1,2		--	123120728(+)	`TCTTGG/CGGGGG`	2	--	ds500¹		1		NA	120
rs114262920^1,2	C,F	--	123120978(+)	`GAGGTG/ACTATA`	2	--	ds500¹		1		WA	118
rs11579856^1,2	H	--	123121127(+)	`CAAAGA/GACCCA`	2	--	ds500¹ ese³		0	--	--	--	--
rs146266963^1,2		--	151743735(+)	`CCTTGA/CCACAT`	1	--	int¹		0	--	--	--	--
rs201991085^1,2		--	151743826(+)	`TTCTT-/GGGGGG`	1	--	int¹		0	--	--	--	--
rs148465533^1,2		--	151743827(+)	`TTCTTG/TGGGGG`	1	--	int¹		0	--	--	--	--
rs3833528^1,2	C	--	151743871(-)	`TCTGT-/TAAGGT`	3	--	int¹ ds500¹		2		NA	4
rs184645265^1,2		--	151743963(+)	`CATGCA/CCCAAA`	1	--	int¹		0	--	--	--	--
rs3790514^1,2	C,F,A,H	--	151744168(-)	`CTTCTA/GTGTTA`	1	--	ut3¹		24		EA NS NA WA CSA	3980
rs190374997^1,2		--	151744251(+)	`GTAAAC/TAGGTA`	1	--	ut3¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TDRKH (151742583 - 151763892 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TDRKH: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TDRKH

DNA2.0 Custom Variant and Variant Library Synthesis for TDRKH

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TDRKH for disorders           About GeneDecksing

OMIM gene information: 609501    OMIM disorders: --

9 diseases for TDRKH:    About MalaCards

extraskeletal myxoid chondrosarcoma myxoid chondrosarcoma chondrosarcoma chronic myeloid leukemia

myeloid leukemia sarcoma leukemia hypoxia

spermatogenic failure

4 Novoseek disease relationships for TDRKH gene About this table

Disease	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
ewings sarcoma	53.9	1	8336942 (1)
sarcoma	10.7	1	10602519 (1)
tumors	0	1	7503813 (1)
cancer	0	1	15917470 (1)

Human Genome Epidemiology (HuGE) Navigator: TDRKH (1 document)

Export disorders for TDRKH gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TDRKH gene, integrated from 9 sources (see all 56):
(articles sorted by number of sources associating them with TDRKH)

Utopia: connect your pdf to the dynamic
world of online information

Complex RNA processing of TDRKH, a novel gene encoding the putative RNA-binding tudor and KH domains. (PubMed id 10767542)^{1, 2, 3} Lamb F.S....Schutte B.C. (2000)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)¹ Hendrickson S.L....O'Brien S.J. (2010)
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)² Gregory S.G.... Bentley D.R. (2006)
Tudor domains bind symmetrical dimethylated arginines. (PubMed id 15955813)¹ Cote J. and Richard S. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. (PubMed id 8125298)¹ Maruyama K. and Sugano S. (1994)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Disorders
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 11022	HGNC: 11713	AceView: TDRKH	Ensembl:ENSG00000182134	euGenes: HUgn11022
ECgene: TDRKH	H-InvDB: TDRKH

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TDRKH	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TDRKH gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TDRKH gene:
Search GeneIP for patents involving TDRKH

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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