|
|
testis development related 1 (non-protein coding)
| |
Aliases
for TDRG1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
Subcategory (RNA class): lncRNA
Quality score for this RNA gene is 8
| Aliases |
|---|
| Testis Development Related 1 (Non-Protein Coding)1 2 | | LINC005321 2 |
| External Ids: | HGNC: 436421 | Entrez Gene: 7322532 | Ensembl: ENSG000002040917 | UniProtKB: Q3Y4523 | | ORGUL members: | |
|---|
| NONCODE:n369376 n368726 n368608 n369375 n368727 | see all 7 |
Export aliases for TDRG1 gene to outside databasesPrevious GC identifer: GC06P040456
|---|
Summaries
for TDRG1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for TDRG1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000006.11 NC_018917.1 NT_007592.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the TDRG1 gene promoter:
AP-2rep TBP STAT1 GATA-1 E47 POU2F1 POU2F1a Hand1 c-Myb
Other transcription factors
Search SABiosciences Chromatin IP Primers for TDRG1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TDRG1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 6p21.2 Ensembl cytogenetic band: 6p21.2 HGNC cytogenetic band: 6p21.2TDRG1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 6 GeneLoc Exon Structure GeneLoc location for GC06P040303: view genomic region
(about GC identifiers)
Start:
|
40,302,693 bp from pter |
End:
|
40,347,631 bp from pter |
Size:
|
44,939 bases |
Orientation:
|
plus strand |
ORGUL member locations:
Legend (see complete legend)
 |
Proteins
for TDRG1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: TDRG1_HUMAN, Q3Y452 (See
protein sequence)Recommended Name: Testis development-related protein 1 Size: 100 amino acids; 10472 Da
Subcellular location: Cytoplasm
Developmental stage: Undetectable in the fetal testis, shows the highest expression level in post-puberty testis, withthe expression levels decreasing afterwards with agingExplore the universe of human proteins at neXtProt for TDRG1: NX_Q3Y452
TDRG1 Protein expression data from MOPED and PaxDb: --
Human Recombinant Protein Products for TDRG1:
TDRG1 Antibody Products:
Assay Products for TDRG1: |
Protein
Domains /
Families
for TDRG1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q3Y452 |
Function
for TDRG1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Animal Models:
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TDRG1 |
|
Pathways & Interactions
for TDRG1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TDRG1
|
Drugs & Compounds
for TDRG1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for TDRG1
Search CenterWatch for drugs/clinical trials and news about TDRG1 
|
Transcripts
for TDRG1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
Unigene Cluster for TDRG1: Testis development related 1 (non-protein coding) Hs.180197 [show with all ESTs]Unigene Representative Sequence: BC0718204 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000448433 ENST00000373170(uc003opg.2) ENST00000451810 ENST00000448559
Additional cDNA sequence: BC033995.2 BC042123.1 BC071820.1 DQ168992.1 NR_024015.1 6 DOTS entries: DT.413661 DT.40112098 DT.92417437 DT.100739587 DT.121396029 DT.99930416
GeneLoc Exon Structure
|
Expression
for TDRG1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| Expression evidence for TDRG1:NONCODE
TDRG1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTCTTGTTGA
About this image
Genevestigator expression for TDRG1
SOURCE GeneReport for Unigene cluster: Hs.180197
UniProtKB/Swiss-Prot: TDRG1_HUMAN, Q3Y452Tissue specificity: Expressed in the testis but not in any other non-reproductive tissues (at protein level). Mainlylocated in spermatogenic cells in seminiferous tubules of adult testis
SABiosciences Custom PCR Arrays for TDRG1
Primer
Products: |  | Browse OriGene genome-wide validated SYBR primer pairs
Browse OriGene validated miRNA SYBR primer pairs
| | | Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TDRG1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TDRG1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TDRG1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TDRG1 |
Orthologs
for TDRG1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
--
ENSEMBL Gene Tree for TDRG1 (if available)
TreeFam Gene Tree for TDRG1 (if available) |
Paralogs
for TDRG1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for TDRG1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 6 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for TDRG1 (40302693 - 40347631 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TDRG1: -- | SABiosciences Cancer Mutation PCR Assays |
|
Disorders
/ Diseases
for TDRG1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TDRG1 for disorders About GeneDecksing
1  disease for TDRG1: About MalaCardstesticular cancer
Export disorders for TDRG1 gene to outside databases
|
Publications
for TDRG1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TDRG1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with TDRG1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of a novel human testis-specific gen e: testis developmental related gene 1 (TDRG1). (PubMed id 22123530)1, 2, 3 Jiang X....Tang Y. (2011)
- [Expression of human testis development related gene 1 in testicular cancer detected by tissue microarray]. (PubMed id 21243750)1 Chen H.Y....Tang Y.X. (2010)
- [Molecular cloning of a novel human testis-specific g ene TDRG1]. (PubMed id 19403381)3 Yin G.M....Zeng Q. (2009)
- The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (2003)
|
External Searches for TDRG1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing TDRG1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TDRG1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing TDRG1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for TDRG1 gene:
Search GeneIP for patents involving TDRG1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for TDRG1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 |
| | | | |
 |
 |
|  | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TDRG1 | | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TDRG1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TDRG1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TDRG1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TDRG1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TDRG1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for TDRG1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TDRG1 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for TDRG1 |
| | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TDRG1 |
| |  | |
|
|
|
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