Aliases for TDRD9 Gene
External Ids for TDRD9 Gene
Previous HGNC Symbols for TDRD9 Gene
Previous GeneCards Identifiers for TDRD9 Gene
GeneCards Summary for TDRD9 Gene
TDRD9 (Tudor Domain Containing 9) is a Protein Coding gene. Among its related pathways are Mitotic Prophase and PIWI-interacting RNA (piRNA) biogenesis. GO annotations related to this gene include nucleic acid binding and helicase activity. An important paralog of this gene is YTHDC2.
UniProtKB/Swiss-Prot for TDRD9 Gene
Probable ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with PIWIL4 and the piP-bodies suggests a participation in the secondary piRNAs metabolic process (By similarity).