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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TDRD7 Gene

protein-coding GIFtS: 54
GCID: GC09P100174

tudor domain containing 7

Explore 7 diseases affiliated with
TDRD7 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Tudor Domain Containing 7¹ ²		RP11-508D10.1²
PCTAIRE2BP¹ ² ³		TRAP²
Tudor Repeat Associator With PCTAIRE-2² ³		Tudor Domain-Containing Protein 7²
PCTAIRE2-Binding Protein² ³		Tudor Repeat Associator With PCTAIRE 2²
CATC4²		Trap³

External Ids:	HGNC: 30831¹	Entrez Gene: 23424²	Ensembl: ENSG00000196116⁷	OMIM: 611258⁵	UniProtKB: Q8NHU6³

Export aliases for TDRD7 gene to outside databases

Previous GC identifers: GC09P095555 GC09P097253 GC09P099214 GC09P069775

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TDRD7:

This gene encodes a component of cytoplasmic RNA granules which are involved in determining the fate of mRNAs. Mutation

in this gene has been associated with pediatric cataracts. Mutation of the similar gene in mice has been associated

with cataracts, glaucoma and a block in spermatogenesis. (provided by RefSeq, May 2011)

UniProtKB/Swiss-Prot: TDRD7_HUMAN, Q8NHU6

Function: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes:

probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during

lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required

during spermatogenesis

Gene Wiki entry for TDRD7

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000009.11 NC_018920.1 NT_008470.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TDRD7 gene promoter:
USF1 RP58 MyoD Lmo2 CUTL1 NF-kappaB AREB6 USF-1 NF-kappaB1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TDRD7 promoter sequence

Search SABiosciences Chromatin IP Primers for TDRD7

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TDRD7

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.33 Ensembl cytogenetic band: 9q22.33 HGNC cytogenetic band: 9q22.33

TDRD7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TDRD7 gene location

GeneLoc information about chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09P100174: view genomic region (about GC identifiers)

Start:	100,174,232 bp from pter	End:	100,258,407 bp from pter
Size:	84,176 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TDRD7_HUMAN, Q8NHU6 (See protein sequence)

Recommended Name: Tudor domain-containing protein 7

Size: 1098 amino acids; 123586 Da

Subunit: Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. Found in a complex containing

CABLES1, CDK16 and CDK17. Interacts with CABLES1, CDK17 and PIWIL1 (By similarity)

Subcellular location: Cytoplasm. Note=Localizes to cytoplasmic RNA granules. Present in chromatoid body (CB) of

spermatids (mammalian counterpart of germplasm, pole plasm or polar granules in Drosophila germ cells), also named

processing bodies (P-bodies) in somatic cells. Detected in the multilobular cytoplasmic CBs (also called

intermitochondrial cementin) in pachytene spermatocytes and as a single perinuclear CB in haploid round spermatids (By

similarity)

1 PDB 3D structure from and Proteopedia for TDRD7:

3RCO (3D)

Secondary accessions: A6NCI6 B2RBX3 B4DG99 B4DXF7 E7EQD4 Q5VV27 Q96JT1 Q9UFF0 Q9Y2M3

Alternative splicing: 3 isoforms: Q8NHU6-1 Q8NHU6-2 Q8NHU6-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TDRD7: NX_Q8NHU6

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q8NHU6

TDRD7 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_055105.2

ENSEMBL proteins:

ENSP00000347444 ENSP00000413608 ENSP00000440717

Human Recombinant Protein Products for TDRD7:

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	Uscn Proteins for TDRD7

Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	ISS	--
GO:0005759	mitochondrial matrix	IEA	--
GO:0030529	ribonucleoprotein complex	--	--
GO:0033391	chromatoid body	ISS	--
GO:0035770	ribonucleoprotein granule	IDA	--

TDRD7 for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for TDRD7

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TDRD7 for domains About GeneDecksing

2 InterPro domains/families:

IPR025605 OST-HTH/LOTUS_dom

IPR002999 Tudor

Graphical View of Domain Structure for InterPro Entry Q8NHU6

ProtoNet protein and cluster: Q8NHU6

1 Blocks protein family: IPB008191 Maternal tudor protein

UniProtKB/Swiss-Prot: TDRD7_HUMAN, Q8NHU6

Similarity: Belongs to the TDRD7 family

Similarity: Contains 3 HTH OST-type domains

Similarity: Contains 2 Tudor domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: TDRD7_HUMAN, Q8NHU6

Function: Component of specific cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes:

probably acts by binding to specific mRNAs and regulating their translation. Required for lens transparency during

lens development, by regulating translation of genes such as CRYBB3 and HSPB1 in the developing lens. Also required

during spermatogenesis

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003729	mRNA binding	IDA	--
GO:0005515	protein binding	IPI	--
GO:0047485	protein N-terminus binding	IEA	--

TDRD7 for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for TDRD7:

Decreased DCP1a protein expres

Large nuclei

6 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Tdrd7):

cellular	endocrine/exocrine gland	immune system	nervous system	reproductive system
vision/eye

TDRD7 for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Tdrd7^tm1.1Chum for TDRD7

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for TDRD7

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		1 QIAGEN miScript miRNA Assays for microRNA that regulate TDRD7:
		hsa-miR-137
		SwitchGear 3'UTR luciferase reporter plasmid: TDRD7 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TDRD7

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Aurora A signaling

Aurora A signaling

1.00

1 BioSystems Pathway for TDRD7

Aurora A signaling

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for TDRD7

STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

5/12 Interacting proteins for TDRD7 (Q8NHU6^{1, 2, 3} ENSP00000347444⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 12)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TACC1	O75410¹^,³, ENSP00000321703⁴	EBI-624505,EBI-624237 I2D: score=4 STRING: ENSP00000321703
ATXN2	Q99700²^,³, ENSP00000366843⁴	MINT-2871018 I2D: score=3 STRING: ENSP00000366843
CDK17	Q00537³, ENSP00000261211⁴	I2D: score=4 STRING: ENSP00000261211
GABPB1	Q06547³, ENSP00000370259⁴	I2D: score=4 STRING: ENSP00000370259
CABLES1	Q8TDN4³, ENSP00000256925⁴	I2D: score=1 STRING: ENSP00000256925

About this table

Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0002089	lens morphogenesis in camera-type eye	IMP	--
GO:0007281	germ cell development	IEA	--
GO:0007283	spermatogenesis	ISS	--
GO:0010608	posttranscriptional regulation of gene expression	IMP	--
GO:0070306	lens fiber cell differentiation	IMP	--

TDRD7 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TDRD7
Search CenterWatch for drugs/clinical trials and news about TDRD7

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TDRD7 gene:

NM_014290.2

Unigene Cluster for TDRD7:

Tudor domain containing 7

Hs.193842 [show with all ESTs]

Unigene Representative Sequence: NM_014290

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000355295(uc004axj.3 uc011lux.2) ENST00000492428 ENST00000422139

ENST00000540902(uc010msp.1 uc011luy.2)

miRNA Products:		OriGene 3'-UTR Clone: TDRD7 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TDRD7
		1 QIAGEN miScript miRNA Assays for microRNA that regulate TDRD7:
		hsa-miR-137
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
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		GenScript: all cDNA clones in your preferred vector: TDRD7 (NM_014290)
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Additional cDNA sequence:

AB025254.1 AK294488.1 AK301954.1 AK310227.1 AK314853.1 AL122110.1 BC028694.1

3 DOTS entries:

DT.100025485 DT.97763231 DT.40305185

24/106 AceView cDNA sequences (see all 106):

BQ716290 CA440211 BM720435 BU741556 Z45201 AL122110 BM712170 AB025254

BQ937857 F07472 AW572604 BM714712 BU685944 BF727465 BM667819 BM676530

BU738752 BX441561 BM727879 AI923488 AA581819 BM669448 AI973259 AI367494

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for TDRD7 About this scheme

ExUns:	1	^	2	^	3	^	4	^	5	^	6	^	7	^	8	^	9	^	10	^	11a	·	11b	^	12	^	13	^	14	^	15a	·	15b	^	16a	·	16b	^	17	^	18
SP1:																	-														-
SP2:																			-
SP3:

ECgene alternative splicing isoforms for TDRD7

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TDRD7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTCTGACTG

About this image

TDRD7 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Outer Nuclear Layer

Mature Rod Cells

Photoreceptors, Retina

Neural Tube

Diencephalic Roof Plate

Neural Tube

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Definitive Endoderm (Generation of beta c...)

See TDRD7 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TDRD7

SOURCE GeneReport for Unigene cluster: Hs.193842

SABiosciences Custom PCR Arrays for TDRD7

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In Situ
Assay Products:

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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for TDRD7 gene from 6/18 species (see all 18) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Tdrd7^{1 , 5}	tudor domain containing 7^{1, 5}	83.61(n)¹ 84.81(a)¹		4 (24.48 cM)⁵ 100121¹ NM_146142.1¹ NP_666254.1¹ 45965334⁵
chicken (Gallus gallus)	Aves	TDRD7¹	tudor domain containing 7	63.35(n) 55.59(a)		430492 XM_428047.3 XP_428047.3
lizard (Anolis carolinensis)	Reptilia	TDRD7⁶	--	59(a)	1 ↔ 1	GL343391.1(76259-128702)
African clawed frog (Xenopus laevis)	Amphibia	Xl.3586²	Xenopus laevis transcribed sequence with weak similarity more	74.34(n)		CD256474.1
zebrafish (Danio rerio)	Actinopterygii	wufi12c12²	Danio rerio mRNA similar to tudor repeat associator more	76.6(n)		BC052137.1
fruit fly (Drosophila melanogaster)	Insecta	CG8920⁶	--	15(a)	1 ↔ 1	2R(16206712-16213478)

ENSEMBL Gene Tree for TDRD7 (if available)
TreeFam Gene Tree for TDRD7 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for TDRD7 gene

TDRD5² TDRKH²

TDRD7 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs78330897^1,2	F	--	69773498(+)	`TCACAA/GGGACG`	1	--	us2k¹		1		WA	118
rs72749670^1,2	C	--	69773516(+)	`CATGAC/TTTCTC`	1	--	us2k¹		0	--	--	--	--
rs113119365^1,2		--	69773583(+)	`GTAGGG/AACACA`	1	--	us2k¹		1		CSA	2
rs34112240^1,2	C,F	--	69774290(+)	`TTCCAT/AACATA`	1	--	us2k¹		3		NA	6
rs113001667^1,2		--	69774481(+)	`ATATAG/TATATA`	1	--	us2k¹		1		CSA	1
rs76308201^1,2	F	--	69774975(+)	`AGACAA/CTAAAA`	1	--	us2k¹		1		WA	118
rs62557473^1,2		--	69775078(+)	`ATGTTC/AGAGAC`	1	--	us2k¹		1		NA	2
rs7857995^1,2	C,F	--	69775350(+)	`GCCGCC/TGGCCG`	1	--	us2k¹		3		WA NA EA	358
rs10982012^1,2		--	69775548(+)	`CAAGCC/GGCGGG`	1	--	ut5¹ ese³		0	--	--	--	--
rs114192152^1,2	C,F	--	69776410(+)	`CTCCCA/GTTCAC`	1	--	int¹		1		WA	118

HapMap Linkage Disequilibrium report for TDRD7 (100174232 - 100258407 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TDRD7: --
Human Gene Mutation Database (HGMD): TDRD7

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TDRD7

DNA2.0 Custom Variant and Variant Library Synthesis for TDRD7

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TDRD7 for disorders About GeneDecksing

OMIM gene information: 611258 OMIM disorders: --

UniProtKB/Swiss-Prot: TDRD7_HUMAN, Q8NHU6

Defects in TDRD7 are the cause of cataract congenital autosomal recessive type 4 (CATC4) [MIM:613887]. An

opacification of the crystalline lens of the eye becoming evident at birth. It frequently results in visual impairment

or blindness. Opacities vary in morphology, are often confined to a portion of the lens, and may be static or

progressive. In general, the more posteriorly located and dense an opacity, the greater the impact on visual function

7 diseases for TDRD7: About MalaCards

cataract-glaucoma cataract glaucoma cataract, congenital, autosomal recessive

blindness breast cancer ataxia

Export disorders for TDRD7 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for TDRD7 gene, integrated from 9 sources (see all 16):
(articles sorted by number of sources associating them with TDRD7)

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Mutations in the RNA granule component TDRD7 cause cataract and glaucoma. (PubMed id 21436445)^{1, 2, 3} Lachke S.A.... Maas R.L. (2011)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Identification of tudor repeat associator with PCTAIRE 2 (Trap). A novel protein that interacts with the N-terminal domain of PCTAIRE 2 in rat brain. (PubMed id 10727952)^{1, 2} Hirose T.... Okada M. (2000)
Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
OST-HTH: a novel predicted RNA-binding domain. (PubMed id 20302647)² Anantharaman V.... Aravind L. (2010)
LOTUS, a new domain associated with small RNA pathways in the germline. (PubMed id 20305267)² Callebaut I. and Mornon J.P. (2010)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration. (PubMed id 16713569)¹ Lim J.... Zoghbi H.Y. (2006)
Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)¹ Rual J.F....Vidal M. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 23424	HGNC: 30831	AceView: TDRD7	Ensembl:ENSG00000196116	euGenes: HUgn23424
ECgene: TDRD7	H-InvDB: TDRD7

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TDRD7	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TDRD7 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TDRD7 gene:
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TDRD7 Gene

tudor domain containing 7

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tudor domain containing 7

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