Aliases for TDRD6 Gene
External Ids for TDRD6 Gene
Previous GeneCards Identifiers for TDRD6 Gene
This gene encodes a tudor domain-containing protein and component of the chromatoid body, a type of ribonucleoprotein granule present in male germ cells. Studies in rodents have demonstrated a role for the encoded protein in spermiogenesis and the nonsense mediated decay (NMD) pathway. This protein is a major autoantigen in human patients with autoimmune polyendocrine syndrome type 1 (APS1). [provided by RefSeq, Oct 2016]
GeneCards Summary for TDRD6 Gene
TDRD6 (Tudor Domain Containing 6) is a Protein Coding gene. Diseases associated with TDRD6 include Autoimmune Polyendocrine Syndrome and Autoimmune Polyendocrine Syndrome Type 1. Among its related pathways are Gene Expression and Mitotic Prophase. An important paralog of this gene is TDRD15.
UniProtKB/Swiss-Prot for TDRD6 Gene
Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression.