Aliases for TDRD6 Gene
External Ids for TDRD6 Gene
Previous GeneCards Identifiers for TDRD6 Gene
This gene encodes a tudor domain-containing protein and component of the chromatoid body, a type of ribonucleoprotein granule present in male germ cells. Studies in rodents have demonstrated a role for the encoded protein in spermiogenesis and the nonsense mediated decay (NMD) pathway. This protein is a major autoantigen in human patients with autoimmune polyendocrine syndrome type 1 (APS1). [provided by RefSeq, Oct 2016]
GeneCards Summary for TDRD6 Gene
TDRD6 (Tudor Domain Containing 6) is a Protein Coding gene. Diseases associated with TDRD6 include Autoimmune Polyendocrine Syndrome Type 1 and Autoimmune Polyendocrine Syndrome. Among its related pathways are Mitotic Prophase and Gene Expression. An important paralog of this gene is TDRD15.
UniProtKB/Swiss-Prot for TDRD6 Gene
Involved in spermiogenesis, chromatoid body formation and for proper precursor and mature miRNA expression.