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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TDRD5 Gene

protein-coding   GIFtS: 43
GCID: GC01P179560

Tudor Domain Containing 5

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tudor Domain Containing 51 2
RP11-427G13.12
TUDOR32
Tudor Domain-Containing Protein 52

External Ids:    HGNC: 206141   Entrez Gene: 1635892   Ensembl: ENSG000001627827   UniProtKB: Q8NAT23   

Export aliases for TDRD5 gene to outside databases

Previous GC identifers: GC01P174993 GC01P176085 GC01P176814 GC01P176800 GC01P176292 GC01P177827 GC01P150787


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TDRD5 Gene: 
TDRD5 (tudor domain containing 5) is a protein-coding gene. Diseases associated with TDRD5 include essential hypertension, and hypertension. An important paralog of this gene is TDRD1.

UniProtKB/Swiss-Prot: TDRD5_HUMAN, Q8NAT2
Function: Required during spermiogenesis to participate in the repression transposable elements and prevent their
mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which
mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi
proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB)
assembly (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_004487.19  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TDRD5 gene promoter:
         MAZR   POU6F1 (c2)   AP-2gamma   HNF-1A   Egr-2   Ik-2   HNF-1   AP-2beta   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTDRD5 promoter sequence
   Search SABiosciences Chromatin IP Primers for TDRD5

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TDRD5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q25.2   Ensembl cytogenetic band:  1q25.2   HGNC cytogenetic band: 1q24.2

TDRD5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TDRD5 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P179560:  view genomic region     (about GC identifiers)

Start:
179,560,748 bp from pter      End:
179,660,407 bp from pter
Size:
99,660 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TDRD5_HUMAN, Q8NAT2 (See protein sequence)
Recommended Name: Tudor domain-containing protein 5  
Size: 981 amino acids; 109737 Da
Subcellular location: Cytoplasm (By similarity). Note=Localizes to chromatoid body (CB) and pi-body (also called
intermitochondrial cementin), 2 cytoplasmic ribonucleoprotein granules involved in RNA processing for
spermatogenesis (By similarity)
Sequence caution: Sequence=BAC03815.1; Type=Frameshift; Positions=819;
1 PDB 3D structure from and Proteopedia for TDRD5:
3S93 (3D)    
Secondary accessions: A1L4G5 B7ZLV0 Q5EBN4 Q5VTV0 Q6ZSK2
Alternative splicing: 2 isoforms:  Q8NAT2-3   Q8NAT2-1   

Explore the universe of human proteins at neXtProt for TDRD5: NX_Q8NAT2

Explore proteomics data for TDRD5 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NAT2

  • TDRD5 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TDRD5 Protein Expression
    REFSEQ proteins (5 alternative transcripts): 
    NP_001186014.1  NP_001186018.1  NP_001186020.1  NP_001186021.1  NP_775804.2  

    ENSEMBL proteins: 
     ENSP00000356586   ENSP00000294848   ENSP00000410744   ENSP00000406052  

    Human Recombinant Protein Products for TDRD5: 
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    OriGene Protein Over-expression Lysate for TDRD5
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for TDRD5
    GenScript Custom Purified and Recombinant Proteins Services for TDRD5
    Novus Biologicals TDRD5 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TDRD5 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0033391chromatoid body ISS--
    GO:0071546pi-body ISS--

    TDRD5 for ontologies           About GeneDecksing



    TDRD5 Antibody Products: 
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    Assay Products for TDRD5: 
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TDRD5 
    Cloud-Clone Corp. CLIAs for TDRD5


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TDRD: Tudor domain containing

    2 InterPro protein domains:
     IPR025605 OST-HTH/LOTUS_dom
     IPR002999 Tudor

    Graphical View of Domain Structure for InterPro Entry Q8NAT2

    ProtoNet protein and cluster: Q8NAT2

    1 Blocks protein domain: IPB008191 Maternal tudor protein

    UniProtKB/Swiss-Prot: TDRD5_HUMAN, Q8NAT2
    Similarity: Belongs to the TDRD5 family
    Similarity: Contains 3 HTH OST-type domains
    Similarity: Contains 1 Tudor domain


    TDRD5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TDRD5_HUMAN, Q8NAT2
    Function: Required during spermiogenesis to participate in the repression transposable elements and prevent their
    mobilization, which is essential for the germline integrity. Probably acts via the piRNA metabolic process, which
    mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi
    proteins and govern the methylation and subsequent repression of transposons. Required for chromatoid body (CB)
    assembly (By similarity)

    Phenotypes:
         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Tdrd5):

     cellular  endocrine/exocrine gland  reproductive system 

    TDRD5 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Tdrd5tm1Sait for TDRD5

       inGenious Targeting Laboratory - Custom generated mouse model solutions for TDRD5 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TDRD5

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TDRD5 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TDRD5 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TDRD5
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate TDRD5:
    hsa-miR-374a* hsa-miR-433
    SwitchGear 3'UTR luciferase reporter plasmidTDRD5 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of TDRD5

    Clone
    Products:
         
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): TDRD5 (NM_001199092)
    Browse Sino Biological Human cDNA Clones
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                         Customized lentivirus expression plasmids for stable overexpression of TDRD5 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for TDRD5
    Search LifeMap BioReagents cell lines for TDRD5
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TDRD5


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TDRD5

    1 Interacting protein for TDRD5 (Q8NAT23) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBR7Q8N8063I2D: score=2 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007286spermatid development ISS--
    GO:0030719P granule organization ISS--
    GO:0043046DNA methylation involved in gamete generation ISS--

    TDRD5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TDRD5

    Search CenterWatch for drugs/clinical trials and news about TDRD5

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TDRD5 gene (5 alternative transcripts): 
    NM_001199085.1  NM_001199089.1  NM_001199091.1  NM_001199092.1  NM_173533.3  

    Unigene Cluster for TDRD5:

    Tudor domain containing 5
    Hs.197354  [show with all ESTs]
    Unigene Representative Sequence: NM_001199085
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000367614(uc021pfm.1) ENST00000294848(uc001gnf.2 uc001gnh.2)
    ENST00000417329 ENST00000444136(uc010pnp.2 uc021pfn.1)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TDRD5
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate TDRD5:
    hsa-miR-374a* hsa-miR-433
    SwitchGear 3'UTR luciferase reporter plasmidTDRD5 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TDRD5
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TDRD5
    Clone
    Products:
         
    OriGene clones in human, mouse for TDRD5 (see all 13)
    OriGene ORF clones in mouse, rat for TDRD5
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 5): TDRD5 (NM_001199092)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TDRD5
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TDRD5
    Sirion Biotech Customized lentivirus for stable overexpression of TDRD5 
                         Customized lentivirus expression plasmids for stable overexpression of TDRD5 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TDRD5
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TDRD5
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TDRD5
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TDRD5

    Additional mRNA sequence: 

    AK092142.1 AK126889.1 AK127370.1 BC043368.1 BC065707.1 BC089387.1 BC130532.1 BC144058.1 

    7 DOTS entries:

    DT.40297531  DT.121345022  DT.95232844  DT.99978871  DT.121345030  DT.121345031  DT.91683930 

    24/26 AceView cDNA sequences (see all 26):

    NM_173533 BE673670 BE674279 AK127370 BC043368 AI630765 BE217803 AW452292 
    AK092142 BG055328 BI520089 BX112064 CD557653 BC065707 BU852780 AX747378 
    AI702961 AK126889 AW589750 AA931671 AW341780 CD706642 BF335791 BF512009 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TDRD5 expression in normal human tissues (normalized intensities)      TDRD5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTGATAAAT
    TDRD5 Expression
    About this image


    TDRD5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/6 selected tissues (see all 6) fully expand
     
     Kidney (Urinary System)    fully expand to see all 6 entries
             Presumptive Podocytes Podocyte Layer
             Metanephros
             visceral organ/metanephros/renal cortex   
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Pre-Granulosa Cells Primordial Follicle
     
     Lower Urinary Tract (Urinary System)    fully expand to see all 2 entries
             visceral organ   
     
     Testis (Reproductive System)
             XY Germ Cells Testis Cord
     
     Gonad
             XY Germ Cells Testis Cord

    See TDRD5 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TDRD5

    SOURCE GeneReport for Unigene cluster: Hs.197354
        SABiosciences Custom PCR Arrays for TDRD5
    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TDRD5
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TDRD5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TDRD5 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Tdrd51 , 5 tudor domain containing 51, 5 82.69(n)1
    79.8(a)1
      1 (67.71 cM)5
    2145751  NM_001134741.11  NP_001128213.11 
     1562552965 
    chicken
    (Gallus gallus)
    Aves TDRD51 tudor domain containing 5 53.6(n)
    43.19(a)
      424421  XM_422264.3  XP_422264.2 
    lizard
    (Anolis carolinensis)
    Reptilia TDRD56
    Uncharacterized protein
    49(a)
    1 ↔ 1
    4(70967973-71014839)
    zebrafish
    (Danio rerio)
    Actinopterygii tdrd51 tudor domain containing 5 46.39(n)
    36.52(a)
      557999  NM_001044850.1  NP_001038315.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG89206
    --
    10(a)
    1 → many
    2R(16206712-16213478)


    ENSEMBL Gene Tree for TDRD5 (if available)
    TreeFam Gene Tree for TDRD5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TDRD5 gene
    TDRD12  TDRD62  TDRD152  RNF172  TDRKH2  

    TDRD5 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2100 SNPs in TDRD5 are shown (see all 2100)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1457980731,2
    Cuntested1179604984(+) AGGGAT/CTCGTC 10 /D syn11Minor allele frequency- C:0.00NA 4550
    rs9135141,2
    C,F,H--179558801(+) TGTCAA/GGTCAG 3 -- us2k120Minor allele frequency- G:0.31NA NS EA WA CSA 1686
    rs1416752951,2
    --179558962(+) TGATCA/GCCACA 3 -- us2k10--------
    rs1179542891,2
    C,F--179559166(+) ATAAAT/GAAGAA 4 -- us2k11Minor allele frequency- G:0.05EA 120
    rs124050141,2
    H--179559322(+) TCTCAG/AGCCCT 4 -- us2k14Minor allele frequency- A:0.00NS EA 386
    rs46524171,2
    C,F,A,H--179559456(+) CACCTC/TTCTTA 4 -- us2k121Minor allele frequency- T:0.05NA NS EA WA CSA 1549
    rs1385823361,2
    --179559508(+) AGTTGA/GGATAA 4 -- us2k10--------
    rs107531991,2
    C,F,A,H--179559632(+) CTTGTC/TAAAAT 4 -- us2k127Minor allele frequency- T:0.40NS EA NA WA 2774
    rs1148620511,2
    C,F--179559802(+) CCTTAC/TGAAGG 4 -- us2k11Minor allele frequency- T:0.09WA 118
    rs730359491,2
    C,F--179559856(+) CAGACG/AACCTT 4 -- us2k13Minor allele frequency- A:0.24WA CSA 122

    HapMap Linkage Disequilibrium report for TDRD5 (179560748 - 179660407 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10/13 variations for TDRD5 (see all 13):    About this table     
    Variant IDTypeSubtypePubMed ID
    esv5000CNV Deletion18987735
    esv2244958CNV Deletion18987734
    esv2719895CNV Deletion23290073
    esv2677942CNV Deletion23128226
    nsv821315CNV Deletion20802225
    esv2544242CNV Deletion19546169
    nsv3732CNV Insertion18451855
    nsv512751CNV Insertion21212237
    esv2598318CNV Insertion19546169
    nsv511720CNV Loss21212237

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TDRD5
    DNA2.0 Custom Variant and Variant Library Synthesis for TDRD5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    2 diseases for TDRD5:    About MalaCards
    essential hypertension    hypertension


    TDRD5 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TDRD5
    Human Genome Epidemiology (HuGE) Navigator: TDRD5 (3 documents)

    Export disorders for TDRD5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TDRD5 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with TDRD5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    2. Follow-up of a major linkage peak on chromosome 1 rev eals suggestive QTLs associated with essential hypertension: GenNet study. (PubMed id 19536175)1, 4 Ehret G.B....Chakravarti A. (2009)
    3. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. (PubMed id 18519826)1, 4 Uhl G.R....Lerman C. (2008)
    4. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. OST-HTH: a novel predicted RNA-binding domain. (PubMed id 20302647)2 Anantharaman V.... Aravind L. (2010)
    8. LOTUS, a new domain associated with small RNA pathways in the germline. (PubMed id 20305267)2 Callebaut I. and Mornon J.P. (2010)
    9. Genome-wide association to body mass index and waist circumference: the Framingham Heart Study 100K project. (PubMed id 17903300)4 Fox C.S....Atwood L.D. (2007)
    10. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1 Olsen J.V....Mann M. (2006)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 163589 HGNC: 20614 AceView: TDRD5 Ensembl:ENSG00000162782 euGenes: HUgn163589
    ECgene: TDRD5 H-InvDB: TDRD5

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TDRD5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TDRD5 gene:
    Search GeneIP for patents involving TDRD5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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