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TDRD3 Gene

protein-coding GIFtS: 50
GCID: GC13P060970

Tudor Domain Containing 3

See related diseases
at

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Tudor Domain Containing 3¹ ²
Tudor Domain-Containing Protein 3²

External Ids:	HGNC: 20612¹	Entrez Gene: 81550²	Ensembl: ENSG00000083544⁷	OMIM: 614392⁵	UniProtKB: Q9H7E2³

Export aliases for TDRD3 gene to outside databases

Previous GC identifers: GC13P054966 GC13P059907 GC13P058768 GC13P058769 GC13P059868 GC13P041662

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TDRD3 Gene:

TDRD3 (tudor domain containing 3) is a protein-coding gene. Diseases associated with TDRD3 include sertoli cell-only syndrome, and fragile x syndrome. GO annotations related to this gene include chromatin binding and methylated histone residue binding. An important paralog of this gene is RMI1.

UniProtKB/Swiss-Prot: TDRD3_HUMAN, Q9H7E2

Function: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In

nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails

associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these

arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress

granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in

dimethylarginine-containing proteins

Gene Wiki entry for TDRD3 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:

NC_000013.11 NT_024524.15 NC_018924.2

Regulatory elements:

Regulatory transcription factor binding sites in the TDRD3 gene promoter:
TBP Sox5 AP-4 NF-kappaB Evi-1 MEF-2A SRY HFH-1 aMEF-2 NF-kappaB1
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TDRD3 promoter sequence

Search Chromatin IP Primers for TDRD3

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TDRD3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 13q21.2 Ensembl cytogenetic band: 13q21.2 HGNC cytogenetic band: 13q14.3

TDRD3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TDRD3 gene location

GeneLoc information about chromosome 13 GeneLoc Exon Structure

GeneLoc location for GC13P060970: view genomic region (about GC identifiers)

Start:	60,970,591 bp from pter	End:	61,148,013 bp from pter
Size:	177,423 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: TDRD3_HUMAN, Q9H7E2 (See protein sequence)

Recommended Name: Tudor domain-containing protein 3

Size: 651 amino acids; 73185 Da

Subunit: Component of mRNA stress granules. Interacts with FMR1, FXR1, FXR2, EWSR1, FUS, SERBP1, EEF1A1 and DDX3X

or DDX3Y, and with the small nuclear ribonucleoprotein-associated proteins SNRPB and SNRPN. Interacts with

'Lys-48'-linked tetra-ubiquitin, but not with monoubiquitin or 'Lys-63'-linked ubiquitin chains. May interact

with the exon junction complex (EJC) composed at least of CASC3, EIF4A3, MAGOH and RBM8A

5 PDB 3D structures from and Proteopedia for TDRD3:

1WJI (3D)

2LTO (3D)

3PMT (3D)

3PNW (3D)

3S6W (3D)

Secondary accessions: B2MWP9 Q53XA6 Q6P992

Alternative splicing: 3 isoforms: Q9H7E2-1 Q9H7E2-2 Q9H7E2-3

Explore the universe of human proteins at neXtProt for TDRD3: NX_Q9H7E2

Explore proteomics data for TDRD3 at MOPED

Post-translational modifications:

Modification sites at neXtProt

Modification sites at PhosphoSitePlus

See TDRD3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (3 alternative transcripts):

NP_001139542.1 NP_001139543.1 NP_110421.1

ENSEMBL proteins:

ENSP00000432703 ENSP00000367126 ENSP00000367113 ENSP00000367114 ENSP00000440190

ENSP00000196169

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:

TDRD: Tudor domain containing

4 InterPro protein domains:

IPR000449 UBA/Ts_N

IPR015940 UBA/transl_elong_EF1B_N_euk

IPR002999 Tudor

IPR009060 UBA-like

Graphical View of Domain Structure for InterPro Entry Q9H7E2

ProtoNet protein and cluster: Q9H7E2

1 Blocks protein domain: IPB008191 Maternal tudor protein

UniProtKB/Swiss-Prot: TDRD3_HUMAN, Q9H7E2

Domain: The Tudor domain specifically recognizes and binds asymmetric dimethylation of histone H3 'Arg-17'

(H3R17me2a) and histones H4 'Arg-3', 2 tags for epigenetic transcriptional activation

Similarity: Contains 1 Tudor domain

Similarity: Contains 1 UBA domain

TDRD3 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: TDRD3_HUMAN, Q9H7E2

Function: Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In

nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails

associated with transcriptional activation (H3R17me2a and H4R3me2a) and recruits proteins at these

arginine-methylated loci. In cytoplasm, may play a role in the assembly and/or disassembly of mRNA stress

granules and in the regulation of translation of target mRNAs by binding Arg/Gly-rich motifs (GAR) in

dimethylarginine-containing proteins

Gene Ontology (GO): Selected molecular function terms (see all 6): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003682	chromatin binding	IDA	--
GO:0003713	transcription coactivator activity	IDA	--
GO:0003723	RNA binding	--	--
GO:0005515	protein binding	--	--
GO:0035064	methylated histone residue binding	IDA	--

TDRD3 for ontologies About GeneDecksing

Phenotypes:
2 GenomeRNAi human phenotypes for TDRD3:

Decreased number of cells in m

Increased cell death in HCC-19

Animal Models:

inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TDRD3

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Gene Editing
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In Situ Assay
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(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

TDRD3_HUMAN, Q9H7E2: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Associated with actively translating

polyribosomes and with mRNA stress granules

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
nucleus	5
cytoskeleton	1
cytosol	1

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Gene Ontology (GO): 3 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	--
GO:0005737	cytoplasm	IEA	--
GO:0035145	colocalizes with exon-exon junction complex	IDA	--

TDRD3 for ontologies About GeneDecksing

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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Custom Pathway & Disease-focused RT² Profiler PCR Arrays for TDRD3
Interactions:

Search GeneGlobe Interaction Network for TDRD3

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for TDRD3 (Q9H7E2³ ENSP00000196169⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 59)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
HIST3H3	Q16695³, ENSP00000355657⁴	I2D: score=1 STRING: ENSP00000355657
FMR1	ENSP00000359506⁴	STRING: ENSP00000359506
FUS	ENSP00000254108⁴	STRING: ENSP00000254108
FXR1	ENSP00000350170⁴	STRING: ENSP00000350170
FXR2	ENSP00000250113⁴	STRING: ENSP00000250113

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Gene Ontology (GO): 3 biological process terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006397	mRNA processing	--	--
GO:0016568	chromatin modification	IEA	--
GO:2001141	regulation of RNA biosynthetic process	IDA	--

TDRD3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for TDRD3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for TDRD3 gene (3 alternative transcripts):

NM_001146070.1 NM_001146071.1 NM_030794.2

Unigene Cluster for TDRD3:

Tudor domain containing 3

Hs.525061 [show with all ESTs]

Unigene Representative Sequence: NM_001146071

8 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000484389 ENST00000377894 ENST00000377881 ENST00000377882 ENST00000463109

ENST00000471710 ENST00000535286(uc010aeg.3 uc001vib.4) ENST00000196169(uc010aef.2 uc001vhz.4 uc001via.3)

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Additional mRNA sequence:

AK023578.1 AK024660.1 BC020604.1 BC030514.1 BC060876.1 BX537910.1 EU643838.1

15 DOTS entries:

DT.100736815 DT.120775377 DT.92453974 DT.116068 DT.97843170 DT.97843173 DT.100783955 DT.100026255

DT.100783957 DT.95262705 DT.95166958 DT.121609917 DT.92453975 DT.95219820 DT.120775370

Selected AceView cDNA sequences (see all 250):

AI394194 AI086727 BC030514 AA417561 BM699010 AA805345 BP370193 BM700162

BC020604 CB149421 NM_030794 AI342429 AI091156 AI373857 W76301 BM982157

AK124246 BQ439903 CA308840 BM741596 AW089362 BU682955 T54090 AI096823

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for TDRD3 (see all 8) About this scheme

ExUns:	1	^	2	^	3	^	4a	·	4b	^	5	^	6a	·	6b	^	7	^	8	^	9	^	10	^	11	^	12	^	13a	·	13b	^	14a	·	14b	^	15	^	16	^	17	^	18
SP1:			-		-										-																				-		-		-
SP2:															-																				-		-		-
SP3:															-																				-		-		-
SP4:
SP5:

ECgene alternative splicing isoforms for TDRD3

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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TDRD3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: GGAGGAAGAA

About this image

TDRD3 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

About this image

TDRD3 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.525061

UniProtKB/Swiss-Prot: TDRD3_HUMAN, Q9H7E2

Tissue specificity: Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas

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In Situ
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(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for TDRD3 gene from Selected species (see all 15) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Tdrd3^{1 , 5}	tudor domain containing 3^{1, 5}	85.6(n)¹ 85.06(a)¹		14 (44.17 cM)⁵ 219249¹ NM_172605.3¹ NP_766193.3¹ 87416639⁵
chicken (Gallus gallus)	Aves	TDRD3¹	tudor domain containing 3	77(n) 76.59(a)		418823 NM_001030822.1 NP_001025993.1
lizard (Anolis carolinensis)	Reptilia	TDRD3⁶	tudor domain containing 3	73(a)	1 ↔ 1	3(75722697-75809685)
African clawed frog (Xenopus laevis)	Amphibia	Xl.8087²	Xenopus laevis transcribed sequence with weak similarity more	80.23(n)		BJ057467.1
zebrafish (Danio rerio)	Actinopterygii	Dr.16828²	Danio rerio cDNA clone IMAGE5604109, partial cds	74.07(n)		BC055609.1
fruit fly (Drosophila melanogaster)	Insecta	CG13472⁶	--	23(a)	1 ↔ 1	3L(14779891-14782765)
worm (Caenorhabditis elegans)	Secernentea	Y50D4C.3⁶	Protein Y50D4C.3 (Y50D4C.3) mRNA, complete cds	22(a)	1 ↔ 1	V(939151-945244) WBGene00021748

ENSEMBL Gene Tree for TDRD3 (if available)
TreeFam Gene Tree for TDRD3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for TDRD3 gene

RMI1²

TDRD3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 13 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs140988326^1,2	C,F	untested¹	61102603(+)	`TCCTCG/AAAATG`	6	/Q /R	mis¹		2		NA EU	5791
rs8002239^1,2	C,F,A	--	60968740(+)	`gaggcG/Cgaggt`	2	--	us2k¹		4		NA CSA	8
rs150392257^1,2		--	60968884(+)	`ATGTGC/TCTGCG`	2	--	us2k¹		0	--	--	--	--
rs138221017^1,2		--	60968903(+)	`TTTAAC/TTTGCT`	2	--	us2k¹		0	--	--	--	--
rs149155394^1,2		--	60969019(+)	`TTGTAG/TGATAT`	2	--	us2k¹		0	--	--	--	--
rs9528128^1,2	C,F,A,H	--	60969094(+)	`caaccT/Cagaca`	2	--	us2k¹		26		NS EA NA CSA WA	2764
rs73208048^1,2	C,F	--	60969158(+)	`GCTTGG/CTTAAA`	2	--	us2k¹		1		NA	120
rs11367306^1,2	C	--	60969295(+)	`AGTGA-/TTTTTT`	2	--	us2k¹ trp³		0	--	--	--	--
rs199924422^1,2	C	--	60969354(+)	`GGCTTG/TAAACT`	2	--	us2k¹		0	--	--	--	--
rs190957729^1,2		--	60969486(+)	`CATTTG/TTTCTA`	3	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TDRD3 (60970591 - 61148013 bp)

Structural Variations
Database of Genomic Variants (DGV) 3 variations for TDRD3: About this table

Variant ID	Type	Subtype	PubMed ID
nsv523359	CNV	Loss	19592680
nsv455903	CNV	Loss	19166990
esv29450	CNV	Gain	19812545

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing TDRD3

DNA2.0 Custom Variant and Variant Library Synthesis for TDRD3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 614392 OMIM disorders: --

3 diseases for TDRD3: About MalaCards

sertoli cell-only syndrome fragile x syndrome breast cancer

1 disease from the University of Copenhagen DISEASES database for TDRD3:

Sertoli cell-only syndrome

TDRD3 for disorders About GeneDecksing

Genetic Association Database (GAD): TDRD3

Export disorders for TDRD3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for TDRD3 gene, integrated from 10 sources (see all 24):
(articles sorted by number of sources associating them with TDRD3)

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Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways. (PubMed id 22267201)^{1, 4} Stolk L....Lunetta K.L. (Nat. Genet. 2012)
TDRD3 is an effector molecule for arginine-methylated histone marks. (PubMed id 21172665)^{1, 2} Yang Y.... Bedford M.T. (Mol. Cell 2010)
Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP. (PubMed id 18664458)^{1, 2} Linder B.... Fischer U. (Hum. Mol. Genet. 2008)
TDRD3, a novel Tudor domain-containing protein, localizes to cytoplasmic stress granules. (PubMed id 18632687)^{1, 2} Goulet I.... Cote J. (Hum. Mol. Genet. 2008)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30. (PubMed id 22363433)¹ Liu K....Min J. (PLoS ONE 2012)
Genetic variants associated with breast size also influence breast cancer risk. (PubMed id 22747683)¹ Eriksson N....Tung J.Y. (BMC Med. Genet. 2012)
Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)¹ Wang J....Yang X. (Mol. Syst. Biol. 2011)
SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay. (PubMed id 20930030)² Kashima I....Izaurralde E. (amp 2010)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 81550	HGNC: 20612	AceView: TDRD3	Ensembl:ENSG00000083544	euGenes: HUgn81550
ECgene: TDRD3	H-InvDB: TDRD3

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for TDRD3	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TDRD3 gene
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Patent Information for TDRD3 gene:
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