Aliases for TDRD12 Gene
External Ids for TDRD12 Gene
GeneCards Summary for TDRD12 Gene
TDRD12 (Tudor Domain Containing 12) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and ATP-dependent helicase activity.
UniProtKB/Swiss-Prot for TDRD12 Gene
Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process (By similarity).