Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TDRD10 Gene

Aliases for TDRD10 Gene

  • Tudor Domain Containing 10 2 3

External Ids for TDRD10 Gene

Summaries for TDRD10 Gene

GeneCards Summary for TDRD10 Gene

TDRD10 (Tudor Domain Containing 10) is a Protein Coding gene. GO annotations related to this gene include RNA binding and nucleotide binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TDRD10 Gene

Genomics for TDRD10 Gene

Genomic Location for TDRD10 Gene

Start:
154,502,219 bp from pter
End:
154,548,148 bp from pter
Size:
45,930 bases
Orientation:
Plus strand

Genomic View for TDRD10 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TDRD10 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TDRD10 Gene

Regulatory Elements for TDRD10 Gene

Proteins for TDRD10 Gene

  • Protein details for TDRD10 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5VZ19-TDR10_HUMAN
    Recommended name:
    Tudor domain-containing protein 10
    Protein Accession:
    Q5VZ19
    Secondary Accessions:
    • A4FU09
    • B0QZ53
    • B4DXV4
    • Q3ZCP1
    • Q3ZCS7
    • Q5SXY7
    • Q6UXV2
    • Q8TCN3

    Protein attributes for TDRD10 Gene

    Size:
    366 amino acids
    Molecular mass:
    40941 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH44864.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI00896.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI00897.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI00898.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI00899.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAQ88562.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAD28538.1; Type=Frameshift; Positions=93, 242; Evidence={ECO:0000305}; Sequence=CAH72850.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI16182.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAI16188.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAQ08365.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAQ10669.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

    Alternative splice isoforms for TDRD10 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for TDRD10 Gene

Proteomics data for TDRD10 Gene at MOPED

Post-translational modifications for TDRD10 Gene

No Post-translational modifications

Other Protein References for TDRD10 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TDRD10 Gene

Domains for TDRD10 Gene

Gene Families for TDRD10 Gene

HGNC:
  • RBM :RNA binding motif (RRM) containing
  • TDRD :Tudor domain containing

Protein Domains for TDRD10 Gene

UniProtKB/Swiss-Prot:

TDR10_HUMAN
Domain:
  • Contains 1 RRM (RNA recognition motif) domain.:
    • Q5VZ19
  • Contains 1 Tudor domain.:
    • Q5VZ19
genes like me logo Genes that share domains with TDRD10: view

Function for TDRD10 Gene

Gene Ontology (GO) - Molecular Function for TDRD10 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0003676 nucleic acid binding --
GO:0003723 RNA binding IEA --
genes like me logo Genes that share ontologies with TDRD10: view

Phenotypes for TDRD10 Gene

genes like me logo Genes that share phenotypes with TDRD10: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TDRD10 Gene

Localization for TDRD10 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TDRD10 Gene COMPARTMENTS Subcellular localization image for TDRD10 gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1
plasma membrane 1

No data available for Gene Ontology (GO) - Cellular Components for TDRD10 Gene

Pathways for TDRD10 Gene

SuperPathways for TDRD10 Gene

No Data Available

Interacting Proteins for TDRD10 Gene

Gene Ontology (GO) - Biological Process for TDRD10 Gene

None

No data available for Pathways by source for TDRD10 Gene

Transcripts for TDRD10 Gene

Unigene Clusters for TDRD10 Gene

Tudor domain containing 10:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TDRD10 Gene

ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12
SP1: - - - - -
SP2: - - - -
SP3: - -
SP4: -
SP5:

Relevant External Links for TDRD10 Gene

GeneLoc Exon Structure for
TDRD10
ECgene alternative splicing isoforms for
TDRD10

Expression for TDRD10 Gene

mRNA expression in normal human tissues for TDRD10 Gene

mRNA differential expression in normal tissues according to GTEx for TDRD10 Gene

This gene is overexpressed in Testis (13.8).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TDRD10 Gene

SOURCE GeneReport for Unigene cluster for TDRD10 Gene Hs.387671

genes like me logo Genes that share expressions with TDRD10: view

Orthologs for TDRD10 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TDRD10 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TDRD10 36
  • 95.1 (n)
  • 93.37 (a)
TDRD10 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TDRD10 36
  • 81.73 (n)
  • 74.68 (a)
TDRD10 37
  • 72 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TDRD10 37
  • 55 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100490913 36
  • 51.3 (n)
  • 40 (a)
Species with no ortholog for TDRD10:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TDRD10 Gene

ENSEMBL:
Gene Tree for TDRD10 (if available)
TreeFam:
Gene Tree for TDRD10 (if available)

Paralogs for TDRD10 Gene

No data available for Paralogs for TDRD10 Gene

Variants for TDRD10 Gene

Sequence variations from dbSNP and Humsavar for TDRD10 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs3811448 - 154,544,102(+) TGCAC(A/G)TCACT missense, reference
rs3811449 -- 154,545,028(+) AGGAA(A/G)CAGCA intron-variant
rs4131514 -- 154,527,613(-) CTCAT(C/T)CTATC intron-variant
rs4240873 -- 154,537,248(+) CTCTT(A/G)CTGCC intron-variant
rs4269769 -- 154,521,606(+) GTCTC(C/G)GGTGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TDRD10 Gene

Variant ID Type Subtype PubMed ID
nsv521887 CNV Gain 19592680
esv23279 CNV Loss 19812545
nsv506960 CNV Insertion 20534489
nsv160554 CNV Loss 16902084

Relevant External Links for TDRD10 Gene

HapMap Linkage Disequilibrium report
TDRD10

Disorders for TDRD10 Gene

Relevant External Links for TDRD10

Genetic Association Database (GAD)
TDRD10
Human Genome Epidemiology (HuGE) Navigator
TDRD10
genes like me logo Genes that share disorders with TDRD10: view

No data available for UniProtKB/Swiss-Prot for TDRD10 Gene

Publications for TDRD10 Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 2 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 49
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4

Products for TDRD10 Gene

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat
  • QIAGEN qRT-PCR Assays for microRNAs that regulate TDRD10
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TDRD10
    • Block miRNA regulation of TDRD10 using miScript Target Protectors

    Sources for TDRD10 Gene

    Back to Top

    Content