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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TDRD1 Gene

protein-coding   GIFtS: 51
GCID: GC10P115929

tudor domain containing 1
 Explore 3 diseases affiliated with
TDRD1 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for TDRD1    

Aliases
for TDRD1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Tudor Domain Containing 11 2
CT41.11 2 3
Cancer/Testis Antigen 41.12 3
Tudor Domain Containing Protein 12
Tudor Domain-Containing Protein 12

External Ids:    HGNC: 117121   Entrez Gene: 561652   Ensembl: ENSG000000956277   OMIM: 6057965   UniProtKB: Q9BXT43   

Export aliases for TDRD1 gene to outside databases

Previous GC identifers: GC10P114870 GC10P115172 GC10P116070 GC10P115627 GC10P115603 GC10P109566


Summaries
for TDRD1 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TDRD1:
This gene is similar to a mouse gene that encodes a tudor domain protein. Alternatively spliced transcript variants
have been described but their full length sequences have not been determined. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: TDRD1_HUMAN, Q9BXT4
Function: Plays a central role during spermatogenesis by participating in the repression transposable elements and
prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which
mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi
proteins and govern the methylation and subsequent repression of transposons. Required for the localization of Piwi
proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts
into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing
the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into
Piwi proteins (By similarity)




Genomic Views
for TDRD1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000010.10  NC_018921.1  NT_030059.13  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TDRD1 gene promoter:
         Egr-3   ISGF-3   Gfi-1   FOXL1   RORalpha1   Egr-2   Max   ARP-1   Pax-4a   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TDRD1 promoter sequence
   Search SABiosciences Chromatin IP Primers for TDRD1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TDRD1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q25.3   Ensembl cytogenetic band:  10q25.3   HGNC cytogenetic band: 10q26.11

TDRD1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TDRD1 gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10P115929:  view genomic region     (about GC identifiers)

Start:
 115,939,029 bp from pter      End:
 115,992,063 bp from pter
Size:
 53,035 bases      Orientation:
 plus strand

Proteins
for TDRD1 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: TDRD1_HUMAN, Q9BXT4 (See protein sequence)
Recommended Name: Tudor domain-containing protein 1  
Size: 1180 amino acids; 132024 Da
Subunit: Found in a mRNP complex, at least composed of TDRD1, TDRD6, TDRD7 and DDX4. Interacts with MAEL. Interacts
with PIWIL1, PIWIL2 and PIWIL4 (when methylated on arginine residues) (By similarity)
Subcellular location: Cytoplasm (By similarity). Note=Component of the meiotic nuage, also named P granule, a
germ-cell-specific organelle required to repress transposon during meiosis (By similarity). Also present in chromatoid
body (By similarity)
Sequence caution: Sequence=AAH35010.1; Type=Miscellaneous discrepancy; Note=Potential poly-A sequence;
Sequence=AAK31985.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAK31985.1;
Type=Miscellaneous discrepancy; Note=Contaminating sequence; Sequence=BAB14982.1; Type=Erroneous initiation;
Note=Translation N-terminally extended; Sequence=BAB14982.1; Type=Miscellaneous discrepancy; Note=Potential poly-A
sequence;
Secondary accessions: A6NEN3 A6NMN2 B3KVI4 B4E2L5 D3DRC2 Q4G0Y8 Q6P518 Q9H7B3
Alternative splicing: 4 isoforms:  Q9BXT4-1   Q9BXT4-2   Q9BXT4-3   Q9BXT4-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TDRD1: NX_Q9BXT4

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BXT4

    • TDRD1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_942090.1  
    ENSEMBL proteins: 
     ENSP00000358288   ENSP00000358286   ENSP00000251864   ENSP00000358287   ENSP00000402794  

    Human Recombinant Protein Products: 
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    Novus Biologicals TDRD1 Protein
    Novus Biologicals TDRD1 Lysates
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for TDRD1

    Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ISS--
    GO:0030529ribonucleoprotein complex ----
    GO:0033391chromatoid body IEA--
    GO:0043186P granule ISS--
    GO:0071546pi-body ISS--


    TDRD1 for ontologies           About GeneDecksing



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    Uscn Antibodies for TDRD1
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    Uscn ELISAs and CLIAs for TDRD1

    Protein Domains /
    Families
    for TDRD1 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    TDRD1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR002893 Znf_MYND
     IPR002999 Tudor

    Graphical View of Domain Structure for InterPro Entry Q9BXT4

    ProtoNet protein and cluster: Q9BXT4

    2 Blocks protein families:
    IPB002999 Tudor domain
    IPB008191 Maternal tudor protein


    UniProtKB/Swiss-Prot: TDRD1_HUMAN, Q9BXT4
    Similarity: Belongs to the TDRD1 family
    Similarity: Contains 1 MYND-type zinc finger
    Similarity: Contains 4 Tudor domains


    Function
    for TDRD1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: TDRD1_HUMAN, Q9BXT4
    Function: Plays a central role during spermatogenesis by participating in the repression transposable elements and
    prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which
    mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi
    proteins and govern the methylation and subsequent repression of transposons. Required for the localization of Piwi
    proteins to the meiotic nuage. Involved in the piRNA metabolic process by ensuring the entry of correct transcripts
    into the normal piRNA pool and limiting the entry of cellular transcripts into the piRNA pathway. May act by allowing
    the recruitment of piRNA biogenesis or loading factors that ensure the correct entry of transcripts and piRNAs into
    Piwi proteins (By similarity)

    miRNA
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    Inhib. RNA
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    OriGene shRNA RFP: TDRD1
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    Gene Editing
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    Clone
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    Cell Line
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    Search LifeMap BioReagents cell lines for TDRD1

    In Situ Assay
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         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TDRD1

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--


    TDRD1 for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Tdrd1tm1Chum for TDRD1
         3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Tdrd1):
     cellular  endocrine/exocrine gland  reproductive system 

    TDRD1 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for TDRD1 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TDRD1

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/6 Interacting proteins for TDRD1 (Q9BXT42, 3 ENSP000002518644) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FYNP062412, 3, ENSP000003576564MINT-8111595 I2D: score=3 STRING: ENSP00000357656
    PLCG1P191742, 3, ENSP000002440074MINT-8112831 I2D: score=3 STRING: ENSP00000244007
    MAELQ96JY03, ENSP000003568464I2D: score=1 STRING: ENSP00000356846
    PPME1Q9Y5703, ENSP000003814614I2D: score=1 STRING: ENSP00000381461
    PIWIL1Q96J943I2D: score=2 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007126meiosis IEA--
    GO:0007275multicellular organismal development IEA--
    GO:0007281germ cell development ISS--
    GO:0007283spermatogenesis ISS--
    GO:0031047gene silencing by RNA ISS--


    TDRD1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TDRD1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TDRD1
    Search CenterWatch for drugs/clinical trials and news about TDRD1 

    Transcripts
    for TDRD1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TDRD1 gene: 
    NM_198795.1  

    Unigene Cluster for TDRD1:

    Tudor domain containing 1
    Hs.333132  [show with all ESTs]
    Unigene Representative Sequence: NM_198795
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000369282 ENST00000369280(uc001lbi.1 uc010qsc.2 uc001lbj.3)
    ENST00000251864(uc001lbg.1 uc001lbh.1) ENST00000369281(uc001lbf.3)
    ENST00000422662

    miRNA
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    hsa-miR-3614-3p hsa-miR-1827 hsa-miR-3190
    SwitchGear 3'UTR luciferase reporter plasmid: TDRD1 3' UTR sequence
    Inhib. RNA
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    Clone
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TDRD1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TDRD1

    Additional cDNA sequence: 

    AF285606.1 AK024735.1 AK122916.1 AK304331.1 AL833340.1 BC035010.2 BC063133.1 BX648664.1 

    4 DOTS entries:

    DT.425526  DT.101981701  DT.95177594  DT.101981702 

    22 AceView cDNA sequences:

    AK024735 AL044913 BX648664 AK122916 NM_198795 BC063133 AI692786 BC035010 
    BG771552 AF285606 AL833340 BP370743 BU561773 CA453178 BV180537 CB136029 
    BQ882979 AA531597 AL044914 AA531454 AW973066 BU561753 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for TDRD1    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b ^ 22 ^
    SP1:                          -                                                                                                                                 
    SP2:                    -     -                                                                                                                 -               
    SP3:                                                                                                                                                            
    SP4:                          -                                                                             -                       -                           

    ExUns: 23 ^ 24 ^ 25 ^ 26a · 26b · 26c ^ 27
    SP1:                                -         
    SP2:                                          
    SP3:                                          
    SP4:                                          


    ECgene alternative splicing isoforms for TDRD1

    Expression
    for TDRD1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TDRD1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AACATATTCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    TDRD1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    1 LifeMap In Vivo Development Anatomical Compartment/Cell 
    Tissue Anatomical Compartment CellCategory (developmental path)
    TestisSeminiferous TubulesSecondary SpermatocyteGerm Cells, Male Gametocytes
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    ES-J1 (Embryonic Stem Cell)Early Embryo, Inner Cell Mass
    Short-term differentiated embryoid bodies (Derivation of embryo...)
    Embryoid bodies (Derivation of embryo...)

    See TDRD1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TDRD1

    SOURCE GeneReport for Unigene cluster: Hs.333132

    UniProtKB/Swiss-Prot: TDRD1_HUMAN, Q9BXT4
    Tissue specificity: Testis and ovary specific. Also expressed in several cancers

        SABiosciences Custom PCR Arrays for TDRD1
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    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TDRD1

    Orthologs
    for TDRD1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for TDRD1 gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Tdrd11 , 5 tudor domain containing 11, 5 76.66(n)1
    72.17(a)1    		   19 (52.00 cM)5
    835611  NM_001002238.21  NP_001002238.11 
     568262095 
    chicken
    (Gallus gallus)    		 Aves TDRD11 tudor domain containing 1 59.43(n)
    48.17(a)    		   423906  XM_421768.3  XP_421768.3 
    lizard
    (Anolis carolinensis)    		 Reptilia TDRD16
    		 --
    		 41(a)
    		 1 ↔ 1
    		 GL343204.1(74738-115161)
    zebrafish
    (Danio rerio)    		 Actinopterygii tdrd11 tudor domain containing 1 51.01(n)
    40.18(a)    		   553522  NM_001164028.1  NP_001157500.1 


    ENSEMBL Gene Tree for TDRD1 (if available)
    TreeFam Gene Tree for TDRD1 (if available) 

    Paralogs
    for TDRD1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TDRD1 gene
    TDRD62  TDRD152  RNF172  
    1 SIMAP similar gene for TDRD1 using alignment to 5 protein entries:     TDRD1_HUMAN (see all proteins):
    CBFA2T1

    TDRD1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for TDRD1
    PGOHUM00000246002


    Genomic Variants
    for TDRD1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/980 NCBI SNPs in TDRD1 are shown (see all 980)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 10 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1832492481,2
    		--115937205(+) TAACCC/TGTAAC 1 -- us2k10--------
    rs1381730901,2
    		--115937273(+) AAGGCC/TTGAGA 1 -- us2k10--------
    rs1865050871,2
    		--115937387(+) TCCTGA/CTGAGA 1 -- us2k10--------
    rs1914424061,2
    		--115937539(+) GAAACC/GATGTG 1 -- us2k10--------
    rs1848756251,2
    		--115937567(+) GTACAG/TCACCT 1 -- us2k10--------
    rs341897561,2
    		C--115937594(+) TTTTC-/TTTTTT 1 -- us2k10--------
    rs1897142011,2
    		--115937618(+) GACAGC/TCTTGC 1 -- us2k10--------
    rs1930844351,2
    		--115937621(+) AGTCTC/TGCTCT 1 -- us2k10--------
    rs1181916891,2
    		F,--115937665(+) TGGCTC/TGGTGA 1 -- us2k11Minor allele frequency- T:0.05EA 120
    rs1850433111,2
    		--115937677(+) ACCTCC/TGCCTC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for TDRD1 (115939029 - 115992063 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TDRD1: --

    SABiosciences Cancer Mutation PCR Assays
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    Disorders / Diseases
    for TDRD1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TDRD1 for disorders           About GeneDecksing

    OMIM gene information: 605796    OMIM disorders: --

    3 diseases for TDRD1:    About MalaCards
    intrahepatic cholangiocarcinoma    cholangiocarcinoma    alzheimer's disease

    1 disease from the University of Copenhagen DISEASES database for TDRD1:
    Sertoli cell-only syndrome
    Human Genome Epidemiology (HuGE) Navigator: TDRD1 (1 document)

    Export disorders for TDRD1 gene to outside databases

    Publications
    for TDRD1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TDRD1 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with TDRD1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. An abundance of X-linked genes expressed in spermatogonia. (PubMed id 11279525)1, 2, 3 Wang P.J.... Page D.C. (2001)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. (PubMed id 22360420)1 Martins-de-Souza D....Bahn S. (2012)
    4. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    5. An integrated workflow for charting the human interac tion proteome: insights into the PP2A system. (PubMed id 19156129)1 Glatter T....Gstaiger M. (2009)
    6. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (2007)
    7. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (2006)
    8. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1 Grupe A....Goate A. (2006)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    10. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)2 Deloukas P.... Rogers J. (2004)

    External Searches for TDRD1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
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    Genome Databases showing TDRD1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56165 HGNC: 11712 AceView: TDRD1 Ensembl:ENSG00000095627 euGenes: HUgn56165
    ECgene: TDRD1 H-InvDB: TDRD1

    Other Databases showing TDRD1 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing TDRD1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TDRD1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TDRD1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TDRD1 gene:
    Search GeneIP for patents involving TDRD1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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