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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TDH Gene

pseudogene   GIFtS: 38
GCID: GC08P011198

L-Threonine Dehydrogenase (Pseudogene)

(Previous name: L-threonine dehydrogenase)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 8

Aliases
L-Threonine Dehydrogenase (Pseudogene)1 2
L-Threonine Dehydrogenase1
Member 1 (Pseudogene)1
Short Chain Dehydrogenase/Reductase Family 14E1
SDR14E1P2

External Ids:    HGNC: 155471   Entrez Gene: 1577392   Ensembl: ENSG000001543167   OMIM: 6151745   UniProtKB: Q8IZJ63   
ORGUL members:         
NONCODE14:n370150 n385351 n385350      

Export aliases for TDH gene to outside databases

Previous GC identifers: GC00U990976 GC08P011076 GC08P011242 GC08P011234 GC08P010127


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TDH Gene:
This gene appears to be an evolving pseudogene of L-threonine 3-dehydrogenase (TDH). In both prokaryotes and
eukaryotes, TDH catalyzes the first of two steps in one of two L-threonine degradation pathways. However, in
human, the single gene with sequence similarity to TDH is not capable of encoding a functional TDH protein; the
predicted protein lacks most of the C-terminus and parts of the NAD+ binding motif when compared to other
species' TDH proteins. This suggests that the human gene is therefore a pseudogene. Transcripts of this gene are
found in all tissues and alternatively spliced transcripts have been described. It is not known if these
transcripts are translated, or if the possible protein product provides any functional role. (provided by RefSeq,
Jul 2008)

GeneCards Summary for TDH Gene: 
TDH (L-threonine dehydrogenase (pseudogene)) is a pseudogene, and is affiliated with the lncRNA class. Diseases associated with TDH include acalculous cholecystitis, and keratolytic winter erythema. GO annotations related to this gene include coenzyme binding and nucleotide binding.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000008.10  NC_018919.2  NT_077531.4  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TDH gene promoter:
         GR   C/EBPbeta   AML1a   p53   Ik-3   GATA-1   E47   Hand1   GR-alpha   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for TDH

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TDH


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8p23.1   Ensembl cytogenetic band:  8p23.1   HGNC cytogenetic band: 8p23.1

TDH Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TDH gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P011198:  view genomic region     (about GC identifiers)

Start:
11,197,146 bp from pter      End:
11,225,961 bp from pter
Size:
28,816 bases      Orientation:
plus strand
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for TDH

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TDH_HUMAN, Q8IZJ6 (See protein sequence)
Recommended Name: Inactive L-threonine 3-dehydrogenase, mitochondrial precursor  
Size: 230 amino acids; 25407 Da
Subcellular location: Mitochondrion (By similarity)
Caution: According to PubMed:12361482, the human TDH gene is an expressed pseudogene encoding non-functional
truncated proteins that are unable to make appropriate contacts with the substrates, L-threonine and NAD(+).
Although all exons expected to encode a functional L-threonine 3-dehydrogenase of 369 residues are present in the
human genome, all transcripts described encode truncated proteins that result from mutations within the gene
causing the loss of acceptor splice site preceding exon 4 and exon 6
Secondary accessions: Q8IZJ5 Q96LV6
Alternative splicing: 3 isoforms:  Q8IZJ6-1   Q8IZJ6-2   Q8IZJ6-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TDH: NX_Q8IZJ6

TDH Protein expression data from MOPED1, PaxDb2 and MAXQB3 : --

Human Recombinant Protein Products for TDH: 

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Cloud-Clone Corp. Proteins for TDH 

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005739mitochondrion IEA--

TDH for ontologies           About GeneDecksing



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Cloud-Clone Corp. CLIAs for TDH


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
SDRE: Short chain dehydrogenase/reductase superfamily / Extended SDR fold

2 InterPro protein domains:
 IPR001509 Epimerase_deHydtase
 IPR016040 NAD(P)-bd_dom

Graphical View of Domain Structure for InterPro Entry Q8IZJ6

ProtoNet protein and cluster: Q8IZJ6

UniProtKB/Swiss-Prot: TDH_HUMAN, Q8IZJ6
Similarity: Belongs to the sugar epimerase family


TDH for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003824catalytic activity IEA--
GO:0050662coenzyme binding IEA--
     
TDH for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for TDH 
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(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TDH

1 Interacting protein for TDH (Q8IZJ63) via UniProtKB, MINT, STRING, and/or I2D
InteractantInteraction Details
GeneCardExternal ID(s)
ADD1P356113I2D: score=4 
About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0044237cellular metabolic process IEA--

TDH for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

TDH for compounds           About GeneDecksing

Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TDH

2 HMDB Compounds for TDH    About this table
CompoundSynonyms CAS #PubMed Ids
2-Hydroxybutyric acid(RS)-2-Hydroxybutyrate (see all 29)600-15-711731084
NAD3-Carbamoyl-1-D-ribofuranosylpyridinium hydroxide 5'-ester with adenosine 5'-pyrophosphate (see all 28)53-84-9--

4 Novoseek inferred chemical compound relationships for TDH gene    About this table
Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
2-amino-3-ketobutyrate 92.6 1 8439306 (1)
threonine 36 9 12867457 (4), 12361482 (2), 10476630 (1), 8439306 (1)
nadh 23.8 1 12361482 (1)
oligonucleotide 20 2 8126441 (1), 10379807 (1)

Search CenterWatch for drugs/clinical trials and news about TDH

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

Unigene Cluster for TDH:

L-threonine dehydrogenase
Hs.583896  [show with all ESTs]
Unigene Representative Sequence: AK057762
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000525246(uc003wtt.1 uc003wtq.1) ENST00000534302(uc003wts.1)
ENST00000531764 ENST00000525664 ENST00000326605
miRNA
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Inhib. RNA
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OriGene ORF clones in mouse, rat for TDH
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GenScript: all cDNA clones in your preferred vector: TDH (NM_178812)
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                     Customized lentivirus expression plasmids for stable overexpression of TDH 
Primer
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  Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TDH
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TDH

Additional mRNA sequence: 

AJ301562.1 AJ301563.1 AK057762.1 AY101186.1 AY101187.1 BC074983.2 BC080558.1 NR_001578.1 
NR_026814.1 

7 DOTS entries:

DT.97841330  DT.70104426  DT.95103741  DT.91750010  DT.100019866  DT.95265121  DT.99948767 

24/43 AceView cDNA sequences (see all 43):

BQ062075 BQ055552 AJ301562 NM_054017 AI474649 BQ059744 BQ057711 AJ301563 
BQ063270 BQ063907 BQ642283 NR_001578 BQ056232 AY101186 BC080558 BQ062689 
BX091784 BM051842 AW193679 BE514180 BI226083 AI439868 AY101187 AK057762 

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for TDH    About this scheme

ExUns: 1 ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12a · 12b · 12c ^ 13
SP1:        -     -                                         -     -                       -         
SP2:                                            -           -     -                                 
SP3:                                            -                 -                                 
SP4:                                                                                                


ECgene alternative splicing isoforms for TDH

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TDH expression in normal human tissues (normalized intensities)      TDH embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ATATATTCCT
TDH Expression
About this image


TDH expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/3 selected tissues (see all 3) fully expand
 
 Nose (Sensory Organs)    fully expand to see all 2 entries
         sensory organ/nose/nasal cavity   
 
 Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
         Sox17-GFP genetically modified stem cells
 
 Lymph (Hematopoietic System)
         LYMPH NODE   

Genevestigator expression for TDH

SOURCE GeneReport for Unigene cluster: Hs.583896

UniProtKB/Swiss-Prot: TDH_HUMAN, Q8IZJ6
Tissue specificity: Expressed in all tissues examined. Detected in most cell types examined, but not observed in
endothelial cells, glioma cell lines and some leukemia cell lines

    SABiosciences Custom PCR Arrays for TDH
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In Situ
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TDH

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and mouse.

Orthologs for TDH gene from 1 species (see representative species )    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Tdh5 L-threonine dehydrogenase   --   14 (33.31 cM) 63492347 


ENSEMBL Gene Tree for TDH (if available)
TreeFam Gene Tree for TDH (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/664 SNPs in TDH are shown (see all 664)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 8 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1489599481,2
--11195177(+) AAGTAA/GACTCG 1 -- us2k10--------
rs1437503331,2
--11195248(+) ATTTGA/CCATAT 1 -- us2k10--------
rs117863131,2
C,F,H--11195250(+) ttgccA/Gtatct 1 -- us2k16Minor allele frequency- G:0.01NS EA NA 424
rs1908237071,2
--11195409(+) ACTGCC/GACCAC 1 -- us2k10--------
rs1477261331,2
--11195504(+) AGCAGC/TTTCAG 1 -- us2k10--------
rs1818482661,2
--11195601(+) AGGAGC/TAATGA 1 -- us2k10--------
rs1426202711,2
--11195605(+) GCAATA/GATTTG 1 -- us2k10--------
rs9566631,2
H--11195632(-) AAATTC/TTGAGT 1 -- us2k16Minor allele frequency- T:0.00EA NS 600
rs9566621,2
C,F,O,A--11195641(-) CAGGAC/TGCTAA 1 -- us2k19Minor allele frequency- T:0.07NA EA 695
rs1859989311,2
--11195690(+) TCTTTA/GGTAAA 1 -- us2k10--------

HapMap Linkage Disequilibrium report for TDH (11197146 - 11225961 bp)

Structural Variations
     Database of Genomic Variants (DGV) 8 variations for TDH:    About this table     
Variant IDTypeSubtypePubMed ID
esv2658364CNV Deletion23128226
esv2661653CNV Deletion23128226
esv273248CNV Insertion20981092
esv269551CNV Insertion20981092
dgv7703n71CNV Loss21882294
esv34097CNV Loss18971310
nsv831233CNV Gain17160897
nsv890354CNV Gain21882294

SABiosciences Cancer Mutation PCR Assays
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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 615174    OMIM disorders: --

11 diseases for TDH:    About MalaCards
acalculous cholecystitis    keratolytic winter erythema    cholecystitis    gastroenteritis
congenital diaphragmatic hernia    hernia    diarrhea    cholera
endotheliitis    breast cancer    leukemia

1 disease from the University of Copenhagen DISEASES database for TDH:
Acalculous cholecystitis

TDH for disorders           About GeneDecksing

2 Novoseek inferred disease relationships for TDH gene    About this table

Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
gastroenteritis 59.8 1 8126441 (1)
poisoning 25.2 3 15182493 (2), 8593076 (1)


Export disorders for TDH gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for TDH gene, integrated from 9 sources (see all 42):
(articles sorted by number of sources associating them with TDH)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The human L-threonine 3-dehydrogenase gene is an expressed pseudogene. (PubMed id 12361482)1, 2, 3, 9 Edgar A.J. (2002)
  2. The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative. (PubMed id 19027726)1, 3 Persson B.... Oppermann U. (2009)
  3. Physical and transcriptional map of the critical region for keratolytic winter erythema (KWE) on chromosome 8p22-p23 between D8S550 and D8S1759. (PubMed id 11896452)1, 3 Appel S.... Rosenthal A. (2002)
  4. DNA sequence and analysis of human chromosome 8. (PubMed id 16421571)2 Nusbaum C....Lander E.S. (2006)
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
  6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
  7. Inhibition and regulation of rat liver L-threonine de hydrogenase by different fatty acids and their derivatives. (PubMed id 11731084)6 Guerranti R....Marinello E. (2001)
  8. Interaction between L-threonine dehydrogenase and aminoacetone synthetase and mechanism of aminoacetone production. (PubMed id 3536927)1 Tressel T....Davis L. (1986)
  9. The thermostable direct hemolysin gene (tdh) of Vibri o hollisae is dissimilar in prevalence to and phylogenetically distant from the tdh genes of other vibrios: implications in the horizontal transfer of the tdh gene. (PubMed id 8871530)9 Nishibuchi M....Ezaki T. (1996)
  10. Detection of a functional insertion sequence responsi ble for deletion of the thermostable direct hemolysin gene (tdh) in Vibrio para haemolyticus. (PubMed id 18598741)9 Kamruzzaman M....Nishibuchi M. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Disorders
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 157739 HGNC: 15547 AceView: C8orf12 Ensembl:ENSG00000154316 euGenes: HUgn157739
ECgene: TDH H-InvDB: TDH

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for TDH Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for TDH gene:
Search GeneIP for patents involving TDH

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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